Tmem106b | transmembrane protein 106B
Physiological systems
21 / 24 physiological systems tested
5 Significantly impacted by the knock-out
Homeostasis/metabolism Reproductive system Growth/size/body region Vision/eye Skeleton
16 No significant impact
3 Not tested
Data collections
Gene metrics:7Significant phenotypes
4Associated diseases
Expression examined in:73Adult tissues
0Embryo tissues
increased circulating alkaline phosphatase level | 1 supporting dataset | Tmem106btm2b(KOMP)Wtsi | homozygote | Early adult | 9.24x10-62 | ||
enlarged epididymis | 1 supporting dataset | Tmem106btm2b(KOMP)Wtsi | homozygote | Early adult | N/A * | ||
decreased body length | 2 supporting datasets | Tmem106btm2b(KOMP)Wtsi | homozygote | Early adult | 1.91x10-6 | ||
increased bone mineral content | 1 supporting dataset | Tmem106btm2b(KOMP)Wtsi | homozygote | Early adult | 6.42x10-5 | ||
abnormal retina inner nuclear layer morphology | 1 supporting dataset | Tmem106bem1(IMPC)Bay | homozygote | Early adult | 2.85x10-7 | ||
decreased total retina thickness | 1 supporting dataset | Tmem106bem1(IMPC)Bay | homozygote | Early adult | 5.69x10-6 | ||
abnormal epididymis morphology | 1 supporting dataset | Tmem106btm2b(KOMP)Wtsi | homozygote | Early adult | N/A * |
| | | | | | | | | |
External links
No external links available for Tmem106b.
All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.
Tmem106bem1(IMPC)Bay | Exon Deletion | | mouse |
Tmem106btm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector es cell |
Tmem106btm1e(KOMP)Wtsi | Targeted, non-conditional allele | | es cell |
Tmem106btm2a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector es cell mouse |
Tmem106btm2b(KOMP)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | mouse |