The IMPC applies a panel of phenotyping screens to characterise single-gene knockout mice by comparison to wild types. Click on the different tabs to visualise significant phenotypes identified by the IMPC, as well as all data that was measured.
An assay measuring the expression of lacZ shows the tissue where the gene is expressed.
Anatomy
Images
Zygosity
Mutant Expr
Brain
N/A
heterozygote
100% (2 of 2)
Ear
N/A
heterozygote
50% (1 of 2)
Embryo
N/A
heterozygote
100% (2 of 2)
Eye
N/A
heterozygote
100% (2 of 2)
Footplate
N/A
heterozygote
100% (2 of 2)
Forebrain
N/A
heterozygote
100% (2 of 2)
Forelimb
N/A
heterozygote
100% (2 of 2)
Handplate
N/A
heterozygote
100% (2 of 2)
Head
N/A
heterozygote
100% (2 of 2)
Heart
N/A
heterozygote
50% (1 of 2)
Hindbrain
N/A
heterozygote
100% (2 of 2)
Hindlimb
N/A
heterozygote
100% (2 of 2)
Liver
N/A
heterozygote
50% (1 of 2)
Lung
N/A
heterozygote
50% (1 of 2)
Mandibular process
N/A
heterozygote
50% (1 of 2)
Maxillary process
N/A
heterozygote
50% (1 of 2)
Midbrain
N/A
heterozygote
100% (2 of 2)
Oral cavity
N/A
heterozygote
50% (1 of 2)
Skin
N/A
heterozygote
50% (1 of 2)
Tail somite
N/A
heterozygote
50% (1 of 2)
Tail
N/A
heterozygote
100% (2 of 2)
Background staining occurs in wild type mice and embryos at an incidental rate.
Anatomy
Background staining in controls (WT)
adrenal gland
0.0%
aorta
0.0%
bone
0.0%
brain
0.0%
brainstem
0.0%
brown adipose tissue
0.0%
cartilage tissue
0.0%
cerebellum
0.0%
cerebral cortex
0.0%
esophagus
0.0%
eye
0.0%
gall bladder
0.0%
heart
0.0%
hippocampus
0.0%
hypothalamus
0.0%
kidney
0.0%
large intestine
0.0%
liver
0.0%
lower urinary tract
0.0%
lung
0.0%
lymph node
0.0%
mammary gland
0.0%
olfactory lobe
0.0%
oral epithelium
0.0%
ovary
0.0%
oviduct
0.0%
pancreas
0.0%
parathyroid gland
0.0%
peripheral nervous system
0.0%
peyers patch
0.0%
pituitary gland
0.0%
prostate gland
0.0%
skeletal muscle
0.0%
skin
0.0%
small intestine
0.0%
spinal cord
0.0%
spleen
0.0%
stomach
0.0%
striatum
0.0%
testis
0.0%
thymus
0.0%
thyroid gland
0.0%
trachea
0.0%
uterus
0.0%
vascular system
0.0%
white adipose tissue
0.0%
Background staining occurs in wild type mice and embryos at an incidental rate.
Background staining occurs in wild type embryos at a measurable rate.
Anatomy
Background staining in controls(WT)
brain
0.0%
ear
0.0%
embryo
0.0%
eye
0.0%
footplate
0.0%
forebrain
0.0%
forelimb
0.0%
handplate
0.0%
head
0.0%
heart
0.0%
hindbrain
0.0%
hindlimb
0.0%
liver
0.0%
lung
0.0%
mandibular process
0.0%
maxillary process
0.0%
midbrain
0.0%
oral cavity
0.0%
skin
0.0%
tail
0.0%
tail somite group
0.0%
Associated Images
Images submitted by IMPC centres for a selection of procedures. Each set of images is available to view in our image comparator.
Echo
M-Mode Images
29 Images
Adult LacZ
LacZ Images Wholemount
28 Images
X-ray
XRay Images Whole Body Lateral Orientation
10 Images
X-ray
XRay Images Skull Dorso Ventral Orientation
10 Images
OPT E9.5
Embryo reconstruction
3 Images
X-ray
XRay Images Whole Body Dorso Ventral
10 Images
Embryo LacZ
LacZ images wholemount
4 Images
Immunophenotyping
Panel A FCS file(s)
8 Images
Immunophenotyping
Panel B FCS file(s)
8 Images
Auditory Brain Stem Response
Click-evoked + 6 to 30kHz tone waveforms (pdf format)
4 Images
Human diseases caused by Coq2 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
Summary table of phenotypes displayed during the Histopathology procedure which are considered significant. Full histopathology data table, including submitted images, can be accessed by clicking any row in this table.
There is no histopathology data for Coq2
IMPC related publications
The table below lists publications which used either products generated by the IMPC or data produced by the phenotyping efforts of the IMPC. These publications have also been associated to Coq2.
No publications found that use IMPC mice or data for Coq2.
Order Mouse and ES Cells
All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.
MGI Allele
Allele Type
Produced
Coq2tm1e(EUCOMM)Hmgu
Targeted, non-conditional allele
ES Cells
Coq2tm1a(EUCOMM)Hmgu
KO first allele (reporter-tagged insertion with conditional potential)
