Gene: Ints12

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Name
integrator complex subunit 12
MGI ID
MGI:1919043
Synonyms
A230056J18Rik 4930529N21Rik 2810027J24Rik 1110020M19Rik Phf22
Viability
Embryo viewer
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
decreased red blood cell distribution width Ints12tm1b(EUCOMM)Wtsi HET Early adult 7.70×10-08
increased circulating magnesium level Ints12tm1a(EUCOMM)Wtsi HET Early adult 1.19×10-05
preweaning lethality, complete penetrance Ints12tm1a(EUCOMM)Wtsi HOM   Early adult 0.00
preweaning lethality, complete penetrance Ints12tm1b(EUCOMM)Wtsi HOM   Early adult 0.00

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Select physiological systems to view:
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 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 4 No  (4/583)  (4/4)  Wholemount images
Aorta 4 No  (1/583)  (2/4)  Wholemount images
Blood vessel 2 No N/A
Bone 4 No N/A
Brain 4 No  (4/583)  (4/4)  Wholemount images
Brainstem 4 No  (2/583)  (2/4)  Wholemount images
Brown adipose tissue 4 No N/A
Cartilage tissue 4 No  (1/583)  (4/4)  Wholemount images
Cerebellum 4 No  (3/583)  (2/4)  Wholemount images
Cerebral cortex 4 No  (2/583)  (2/4)  Wholemount images
Esophagus 2 No  (7/407)  (2/2)  Wholemount images
Eye 4 No  (2/4)  Wholemount images
Gall bladder 4 No  (2/4)  Wholemount images
Heart 4 No  (2/583)  (4/4)  Wholemount images
Hippocampus 4 No  (3/583)  (2/4)  Wholemount images
Hypothalamus 4 No  (2/583)  (2/4)  Wholemount images
Kidney 4 No  (21/583)  (2/4)  Wholemount images
Large intestine 4 No  (10/583)  (3/4)  Wholemount images
Liver 4 No  (1/4)  Wholemount images
Lower urinary tract 4 No  (1/583)  (3/4)  Wholemount images
Lung 4 No  (2/583)  (4/4)  Wholemount images
Lymph node 4 No  (1/583)  (1/4)  Wholemount images
Mammary gland 4 No  (1/4)  Wholemount images
Esophagus 2 No  (2/2) N/A
Olfactory lobe 4 No  (2/583)  (2/4)  Wholemount images
Oral epithelium 2 No N/A
Ovary 4 No  (1/583)  (2/4)  Wholemount images
Oviduct 4 No  (2/4)  Wholemount images
Pancreas 4 No  (5/583)  (1/4) N/A
Parathyroid gland 4 No  (1/563)  (3/4)  Wholemount images
Peripheral nervous system 4 No  (2/583)  (4/4)  Wholemount images
Peyer's patch 2 No  (1/176) N/A
Peyer's patch 2 No  (2/2)  Wholemount images
Pituitary gland 4 No  (1/583)  (3/4)  Wholemount images
Prostate gland 4 No  (12/583) N/A
Skeletal muscle 2 No  (2/2)  Wholemount images
Skeletal muscle tissue 2 No  (2/2) N/A
Skin 4 No  (1/583)  (2/4)  Wholemount images
Small intestine 4 No  (9/583)  (4/4)  Wholemount images
Spinal cord 4 No  (3/583)  (4/4)  Wholemount images
Spleen 4 No  (3/583)  (2/4) N/A
Stomach 4 No  (13/583)  (3/4)  Wholemount images
Striatum 4 No  (3/583)  (2/4)  Wholemount images
Testis 4 No  (6/583)  (2/4)  Wholemount images
Thymus 4 No  (1/583)  (2/4)  Wholemount images
Thyroid gland 4 No  (17/583)  (2/4)  Wholemount images
Trachea 4 No  (3/583)  (4/4)  Wholemount images
Uterus 4 No  (2/4)  Wholemount images
Vascular system 2 No  (2/2)  Wholemount images
White adipose tissue 4 No N/A
LacZ Section Images

View all 20 images

View all 13 images

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
3  (6/505)  (1/3) N/A
3  (1/505)  (1/3) N/A
3  (1/506)  (3/3) N/A
3  (1/505)  (1/3) N/A
3  (1/505)  (1/3) N/A
3  (1/505)  (1/3) N/A
3  (1/505)  (3/3) N/A
3  (1/505)  (1/3) N/A
3  (5/505)  (3/3) N/A
3  (1/505)  (1/3) N/A
3  (6/505)  (1/3) N/A
3  (1/505)  (3/3) N/A
3  (1/503)  (1/3) N/A
3  (1/503)  (1/3) N/A
3  (1/505)  (1/3) N/A
3  (1/505)  (1/3) N/A
3  (1/505)  (1/3) N/A
3  (1/503)  (1/3) N/A
3  (1/505)  (3/3) N/A
3  (1/505)  (3/3) N/A
3  (1/505)  (1/3) N/A

 Associated Images

Echo: M-Mode Images
32 Images
Adult LacZ: LacZ Images Wholemount
23 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
10 Images
X-ray: XRay Images Whole Body Dorso Ventral
10 Images
X-ray: XRay Images Whole Body Lateral Orientation
10 Images
Embryo LacZ: LacZ images wholemount
4 Images
Immunophenotyping: Panel B FCS file(s)
8 Images
Immunophenotyping: Panel A FCS file(s)
8 Images
Auditory Brain Stem Response: Click-evoked + 6 to 30kHz tone waveforms (pdf format)
4 Images
Legacy Phenotype Associated Images

View all 96 images

 Disease Models

No associations by disease annotation and gene orthology found.
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MGI Allele Allele Type Produced
Ints12tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Ints12tm1b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre) Mice
Ints12tm1c(EUCOMM)Wtsi Wild type floxed exon (post-Flp) Mice

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