Genes Phenotypes

Gene: Tmprss6

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Name
transmembrane serine protease 6
MGI ID
MGI:1919003
Synonyms
1300008A22Rik matriptase-2
Viability
N/A
Embryo viewer
N/A
Other links
MGI   Ensembl  
Significant phenotypes (13) Measurements chart (188) All data table (446)
Expression & images (0) Disease models (0) Order (3)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
abnormal behavior Tmprss6tm1b(EUCOMM)Wtsi HOM Early adult 8.05×10-07
abnormal skin morphology Tmprss6tm1b(EUCOMM)Wtsi HOM Early adult 0.00
short tibia Tmprss6tm1b(EUCOMM)Wtsi HOM Early adult 0.00
increased circulating alkaline phosphatase level Tmprss6tm1b(EUCOMM)Wtsi HOM Early adult 9.40×10-05
decreased grip strength Tmprss6tm1b(EUCOMM)Wtsi HOM Early adult 4.55×10-05
abnormal coat/hair pigmentation Tmprss6tm1b(EUCOMM)Wtsi HOM Early adult 2.76×10-09
decreased bone mineral density Tmprss6tm1b(EUCOMM)Wtsi HOM Early adult 2.02×10-05
decreased circulating alkaline phosphatase level Tmprss6tm1b(EUCOMM)Wtsi HOM Early adult 9.40×10-05
increased fasting circulating glucose level Tmprss6tm1b(EUCOMM)Wtsi HOM Early adult 2.06×10-10
decreased prepulse inhibition Tmprss6tm1b(EUCOMM)Wtsi HOM Early adult 4.07×10-13
hypoactivity Tmprss6tm1b(EUCOMM)Wtsi HOM Early adult 1.59×10-10
abnormal coat/ hair morphology Tmprss6tm1b(EUCOMM)Wtsi HOM Early adult 4.11×10-08
abnormal coat appearance Tmprss6tm1b(EUCOMM)Wtsi HOM Early adult 2.76×10-09

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 Expression

Expression data not available

 Associated Images

Gross Pathology and Tissue Collection
4 Images

 Disease Models

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MGI Allele Allele Type Produced
Tmprss6tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Tmprss6tm1b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre) Mice
Tmprss6tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Targeting vectors, ES Cells