Genes Phenotypes

Gene: Tmprss6

Name
transmembrane serine protease 6
MGI ID
MGI:1919003
Synonyms
matriptase-2 1300008A22Rik
Viability
N/A
View
N/A
Other links
MGI   Ensembl  
Significant phenotypes (13) Measurements chart (188) All data table (328)
Expression & images (0) Disease models (0) Order (3)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
increased circulating alkaline phosphatase level Tmprss6tm1b(EUCOMM)Wtsi HOM postnatal 9.40×10-05
decreased circulating alkaline phosphatase level Tmprss6tm1b(EUCOMM)Wtsi HOM postnatal 9.40×10-05
abnormal behavior Tmprss6tm1b(EUCOMM)Wtsi HOM postnatal 1.04×10-06
abnormal skin morphology Tmprss6tm1b(EUCOMM)Wtsi HOM postnatal 0.00
decreased grip strength Tmprss6tm1b(EUCOMM)Wtsi HOM postnatal 7.86×10-05
decreased prepulse inhibition Tmprss6tm1b(EUCOMM)Wtsi HOM postnatal 4.63×10-13
increased fasted circulating glucose level Tmprss6tm1b(EUCOMM)Wtsi HOM postnatal 9.36×10-11
abnormal coat appearance Tmprss6tm1b(EUCOMM)Wtsi HOM postnatal 4.13×10-09
abnormal coat/hair pigmentation Tmprss6tm1b(EUCOMM)Wtsi HOM postnatal 4.13×10-09
short tibia Tmprss6tm1b(EUCOMM)Wtsi HOM postnatal 8.14×10-39
hypoactivity Tmprss6tm1b(EUCOMM)Wtsi HOM postnatal 1.93×10-10
decreased bone mineral density Tmprss6tm1b(EUCOMM)Wtsi HOM postnatal 5.29×10-05
abnormal coat/ hair morphology Tmprss6tm1b(EUCOMM)Wtsi HOM postnatal 6.15×10-08

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 Expression

Expression data not available

 Associated Images

X-ray: XRay Images Dorso Ventral
8 Images
X-ray: XRay Images Lateral Orientation
8 Images
Gross Pathology and Tissue Collection
4 Images

 Disease Models

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 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Tmprss6tm1b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre) Mice
Tmprss6tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Tmprss6tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Targeting vectors, ES Cells