Gene: Tmprss6

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Name
transmembrane serine protease 6
MGI ID
MGI:1919003
Synonyms
matriptase-2 1300008A22Rik
Viability
N/A
Embryo viewer
N/A
Other links
Expression & images (0) Disease models (0) Order (3)
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
abnormal coat/hair pigmentation Tmprss6tm1b(EUCOMM)Wtsi HOM Early adult 8.26×10-09
increased fasting circulating glucose level Tmprss6tm1b(EUCOMM)Wtsi HOM Early adult 1.92×10-05
increased circulating calcium level Tmprss6tm1b(EUCOMM)Wtsi HOM Early adult 1.54×10-08
decreased grip strength Tmprss6tm1b(EUCOMM)Wtsi HOM   Early adult 1.48×10-05
hypoactivity Tmprss6tm1b(EUCOMM)Wtsi HOM   Early adult 1.38×10-10
increased memory-marker CD4-negative NK T cell number Tmprss6tm1b(EUCOMM)Wtsi HOM Early adult 4.52×10-06
abnormal coat appearance Tmprss6tm1b(EUCOMM)Wtsi HOM Early adult 8.26×10-09
decreased circulating triglyceride level Tmprss6tm1b(EUCOMM)Wtsi HOM Early adult 4.70×10-07
decreased CD8-positive, alpha-beta T cell number Tmprss6tm1b(EUCOMM)Wtsi HOM Early adult 3.60×10-06
immune system phenotype Tmprss6tm1b(EUCOMM)Wtsi HOM   Early adult 5.61×10-07
increased thigmotaxis Tmprss6tm1b(EUCOMM)Wtsi HOM Early adult 9.30×10-07
decreased prepulse inhibition Tmprss6tm1b(EUCOMM)Wtsi HOM   Early adult 1.14×10-09
abnormal behavior Tmprss6tm1b(EUCOMM)Wtsi HOM Early adult 9.30×10-07
abnormal skin morphology Tmprss6tm1b(EUCOMM)Wtsi HOM Early adult 0.00
increased startle reflex Tmprss6tm1b(EUCOMM)Wtsi HOM Early adult 6.36×10-05
short tibia Tmprss6tm1b(EUCOMM)Wtsi HOM Early adult 5.75×10-37
decreased exploration in new environment Tmprss6tm1b(EUCOMM)Wtsi HOM Early adult 7.17×10-08
increased Ly6C-positive mature NK cell number Tmprss6tm1b(EUCOMM)Wtsi HOM Early adult 2.61×10-06
increased effector memory CD8-positive, alpha-beta T cell number Tmprss6tm1b(EUCOMM)Wtsi HOM Early adult 8.97×10-07
increased anxiety-related response Tmprss6tm1b(EUCOMM)Wtsi HOM Early adult 2.42×10-08
abnormal coat/ hair morphology Tmprss6tm1b(EUCOMM)Wtsi HOM Early adult 4.11×10-08
decreased NK cell number Tmprss6tm1b(EUCOMM)Wtsi HOM Early adult 1.33×10-08

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 Expression

Expression data not available

 Associated Images

X-ray: XRay Images Whole Body Lateral Orientation
16 Images
X-ray: XRay Images Whole Body Dorso Ventral
16 Images
Gross Pathology and Tissue Collection
4 Images
Immunophenotyping: Panel B FCS file(s)
12 Images
Immunophenotyping: Panel A FCS file(s)
12 Images

 Disease Models

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MGI Allele Allele Type Produced
Tmprss6tm1b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre) Mice
Tmprss6tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Tmprss6tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Targeting vectors, ES Cells