Gene: Gimap6

Name
GTPase, IMAP family member 6
MGI ID
MGI:1918876
Synonyms
4833419H03Rik Ian6
Viability
Homozygous - Viable
Other links
View data by physiological system
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
increased memory-marker CD4-negative NK T cell number Gimap6tm1a(KOMP)Wtsi HOM postnatal 0.00
decreased mean corpuscular volume Gimap6tm1b(KOMP)Wtsi HOM postnatal 1.79×10-14
decreased circulating glucose level Gimap6tm1b(KOMP)Wtsi HOM postnatal 9.46×10-05
increased circulating HDL cholesterol level Gimap6tm1b(KOMP)Wtsi HOM postnatal 1.68×10-05
decreased circulating amylase level Gimap6tm1a(KOMP)Wtsi HOM postnatal 1.74×10-08
decreased mean corpuscular hemoglobin Gimap6tm1b(KOMP)Wtsi HOM postnatal 2.60×10-31
decreased memory-marker CD4-negative NK T cell number Gimap6tm1a(KOMP)Wtsi HOM postnatal 0.00
increased blood urea nitrogen level Gimap6tm1b(KOMP)Wtsi HOM postnatal 6.63×10-11
increased monocyte cell number Gimap6tm1a(KOMP)Wtsi HOM postnatal 2.26×10-05
decreased total body fat amount Gimap6tm1b(KOMP)Wtsi HOM postnatal 9.11×10-07
increased fasted circulating glucose level Gimap6tm1b(KOMP)Wtsi HOM postnatal 6.04×10-06
decreased circulating iron level Gimap6tm1b(KOMP)Wtsi HOM postnatal 6.94×10-05
decreased CD4-negative NK T cell number Gimap6tm1a(KOMP)Wtsi HOM postnatal 0.00
decreased NK T cell number Gimap6tm1a(KOMP)Wtsi HOM postnatal 1.60×10-06
increased circulating cholesterol level Gimap6tm1b(KOMP)Wtsi HOM postnatal 4.79×10-06
increased heart weight Gimap6tm1b(KOMP)Wtsi HOM postnatal 8.01×10-07

Download data as:  TSV  XLS

Filtered by: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584) N/A
Aorta 2 No N/A
Brain 2 No  (2/2) N/A
Brainstem 2 No  (2/2) N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No N/A
Cerebellum 2 No N/A
Cerebral cortex 2 No N/A
Epididymis 2 No  (18/134) N/A
Esophagus 2 No  (7/415)  (2/2) N/A
Eye 2 No N/A
Heart 2 No  (2/2) N/A
Hippocampus 2 No N/A
Hypothalamus 2 No N/A
Kidney 2 No  (18/584)  (2/2) N/A
Large intestine 2 No  (10/584)  (2/2) N/A
Liver 2 No N/A
Lower urinary tract 2 No N/A
Lung 2 No N/A
Lymph node 2 No  (2/2) N/A
Mammary gland 2 No N/A
Midbrain 2 No N/A
Olfactory lobe 2 No N/A
Ovary 2 No  (1/584)  (1/2) N/A
Oviduct 2 No  (1/2) N/A
Pancreas 2 No  (5/584)  (2/2) N/A
Peripheral nervous system 2 No N/A
Peyer's patch 2 No  (2/2) N/A
Pituitary gland 2 No  (2/2) N/A
Prostate gland 2 No  (12/584) N/A
Skeletal muscle 2 No N/A
Skin 2 No N/A
Small intestine 2 No  (9/584)  (2/2) N/A
Spinal cord 2 No N/A
Spleen 2 No  (2/584)  (2/2) N/A
Stomach 2 No  (12/584) N/A
Striatum 2 No N/A
Submandibular gland 2 No  (2/132)  (1/2) N/A
Testis 2 No  (2/584)  (1/2) N/A
Thalamus 2 No N/A
Thymus 2 No  (2/2) N/A
Thyroid gland 2 No  (15/584)  (2/2) N/A
Trachea 2 No N/A
Urinary bladder 2 No N/A
Uterus 2 No  (1/2) N/A
Vascular system 2 No  (1/2) N/A
Vesicular gland 2 No N/A
White adipose tissue 2 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2  (6/485)  (1/3) N/A
Dorsal root ganglion 1  (1/47) Image Only N/A
Ear 2  (1/485) N/A
Embryo 2  (1/485)  (2/3)  Wholemount images
Eye 2  (1/485) N/A
Foot 2  (1/485)  (1/3) N/A
Forebrain 2  (1/485) N/A
Forelimb 2  (1/485)  (1/3) N/A
Fronto-nasal process 1  (1/48) N/A
Gut 1  (1/50)  (1/1) N/A
Hand 2  (1/485)  (1/3) N/A
Head 2  (5/485)  (2/3) N/A
Heart 2  (1/485)  (2/3) N/A
Hindbrain 2  (6/485)  (1/3) N/A
Hindlimb 2  (1/485)  (1/3) N/A
Liver 2  (1/485) N/A
Lung 2  (1/485) N/A
Mandibular process 2  (1/485)  (2/3) N/A
Maxillary process 2  (1/485)  (2/3) N/A
Midbrain 2  (1/485) N/A
Nose 2  (1/51)  (2/2) N/A
Oral cavity 2  (1/485) N/A
Skin 2  (1/485) N/A
Spinal cord 2  (1/50)  (1/2) N/A
Tail 2  (1/485)  (2/3) N/A
Tail somite 2  (1/485) N/A
Thoracic vertebral cartilage condensation 1  (1/46)  (1/1) N/A

 Associated Images

Spleen Immunophenotyping: Images associated with FACS analysis
6 Images
Sleep Wake: Wake state (bmp file)
11 Images
X-ray: XRay Images Skull Lateral Orientation
24 Images
Embryo LacZ: LacZ images wholemount
16 Images
X-ray: XRay Images Dorso Ventral
51 Images
X-ray: XRay Images Lateral Orientation
38 Images
X-ray: XRay Images Forepaw
24 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
23 Images
Anti-nuclear antibody assay
6 Images
DSS Histology
8 Images

 Disease Models

No associations by disease annotation and gene orthology found.
Please visit the desktop version to see this section

 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Gimap6tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Gimap6tm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre) Mice
Gimap6tm45182(L1L2_gt0) Targeting vectors

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