Piezo2 | piezo-type mechanosensitive ion channel component 2
Physiological systems
19 / 24 physiological systems tested
5 Significantly impacted by the knock-out
Homeostasis/metabolism Embryo Growth/size/body region Behavior/neurological Mortality/aging
14 No significant impact
5 Not tested
Data collections
Gene metrics:4Significant phenotypes
7Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
preweaning lethality, complete penetrance | 1 supporting dataset | Piezo2em1(IMPC)J | homozygote | Early adult | N/A * | ||
increased vertical activity | 1 supporting dataset | Piezo2em2(IMPC)J | heterozygote | Early adult | 7.33x10-6 | ||
preweaning lethality, complete penetrance | 1 supporting dataset | Piezo2em2(IMPC)J | homozygote | Early adult | N/A * | ||
abnormal embryo size | 1 supporting dataset | Piezo2em2(IMPC)J | homozygote | E18.5 | N/A * | ||
increased circulating triglyceride level | 1 supporting dataset | Piezo2em2(IMPC)J | heterozygote | Early adult | 7.9x10-5 |
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External links
No external links available for Piezo2.
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Piezo2em1(IMPC)J | Exon Deletion | | mouse |
Piezo2em2(IMPC)J | Exon Deletion | | mouse |
Piezo2tm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
Piezo2tm1e(KOMP)Wtsi | Targeted, non-conditional allele | | ES Cell |