Sfpq | splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated)

GeneMGI:1918764Synonyms: 2810416M14Rik, 5730453G22Rik, +5 more

Physiological systems

15 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Homeostasis/metabolism Growth/size/body region Craniofacial

12 No significant impact

9 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Viability data
Body weight measurements
Embryo imaging data
Gene metrics:2Significant phenotypes
1Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased circulating amylase level1 supporting datasetSfpqtm1a(EUCOMM)WtsiheterozygoteEarly adult8.47x10-5 
abnormal snout morphology1 supporting datasetSfpqtm1a(EUCOMM)WtsiheterozygoteEarly adult5.59x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Sfpqtm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Sfpqtm1e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell

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