Nbas | neuroblastoma amplified sequence

GeneMGI:1918419Synonyms: 4933425L03Rik

Physiological systems

19 / 24 physiological systems tested

5 Significantly impacted by the knock-out

 Adipose tissue Nervous system Vision/eye Mortality/aging Cardiovascular system

14 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:8Significant phenotypes
4Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

persistence of hyaloid vascular system1 supporting datasetNbastm1b(EUCOMM)HmguheterozygoteEarly adult8.17x10-6 
decreased total body fat amount1 supporting datasetNbastm1b(EUCOMM)HmguheterozygoteEarly adult1.12x10-5 
abnormal vitreous body morphology1 supporting datasetNbastm1b(EUCOMM)HmguheterozygoteEarly adult1.15x10-8 
preweaning lethality, complete penetrance1 supporting datasetNbastm1b(EUCOMM)HmguhomozygoteEarly adultN/A * 
abnormal retina morphology1 supporting datasetNbastm1b(EUCOMM)HmguheterozygoteEarly adult5.33x10-10 
abnormal retina blood vessel morphology1 supporting datasetNbastm1b(EUCOMM)HmguheterozygoteEarly adult2.15x10-7 
abnormal retina vasculature morphology1 supporting datasetNbastm1b(EUCOMM)HmguheterozygoteEarly adult4.23x10-8 
abnormal optic disk morphology1 supporting datasetNbastm1b(EUCOMM)HmguheterozygoteEarly adult7.69x10-16 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Nbastm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Nbastm1b(EUCOMM)HmguReporter-tagged deletion allele (with selection cassette)mouse
Nbastm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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