Gene: Setd2

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Name
SET domain containing 2
MGI ID
MGI:1918177
Synonyms
4921524K10Rik KMT3A
Viability
Embryo viewer
N/A
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
prolonged QRS complex duration Setd2tm1b(NCOM)Mfgc HOM Early adult 6.13×10-05
short tibia Setd2tm1b(NCOM)Mfgc HOM Early adult 3.36×10-07
decreased exploration in new environment Setd2tm1b(NCOM)Mfgc HOM Early adult 6.95×10-05
decreased mean corpuscular volume Setd2tm1b(NCOM)Mfgc HOM Early adult 2.29×10-05
increased grip strength Setd2tm1b(NCOM)Mfgc HOM Early adult 5.43×10-05
increased heart weight Setd2tm1b(NCOM)Mfgc HOM Early adult 6.87×10-05
decreased prepulse inhibition Setd2tm1b(NCOM)Mfgc HOM   Early adult 2.47×10-05

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Viewing: all phenotypes

 Expression

Expression data not available

 Associated Images

X-ray: XRay Images Whole Body Dorso Ventral
10 Images
X-ray: XRay Images Whole Body Lateral Orientation
10 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
10 Images
X-ray: XRay Images Skull Lateral Orientation
10 Images
Eye Morphology: Images Ophthalmoscopy
21 Images
Gross Pathology and Tissue Collection
8 Images
Histopathology
7 Images
Immunophenotyping: Panel A FCS file(s)
2 Images
Immunophenotyping: Panel B FCS file(s)
2 Images

 Disease Models

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 Histopathology

Phenotype Allele Zygosity Sex Life Stage
Femur - developmental hypertrophy Setd2tm1b(NCOM)Mfgc HOM Early adult
Tibia - developmental hypertrophy Setd2tm1b(NCOM)Mfgc HOM Early adult
Eye with optic nerve - developmental and structural abnormality Setd2tm1b(NCOM)Mfgc HOM Early adult

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MGI Allele Allele Type Produced
Setd2tm1a(NCOM)Mfgc KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Setd2tm1b(NCOM)Mfgc Reporter-tagged deletion allele (post-Cre) Mice, Tissue

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