Gene: Ints10

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Name
integrator complex subunit 10
MGI ID
MGI:1918135
Synonyms
4921521J11Rik
Embryo viewer
N/A
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
microphthalmia Ints10tm1b(KOMP)Wtsi HET E12.5 0.00
preweaning lethality, complete penetrance Ints10tm1b(KOMP)Wtsi HOM Early adult 0.00
embryonic growth retardation Ints10tm1b(KOMP)Wtsi HET E12.5 0.00
abnormal embryo turning Ints10tm1b(KOMP)Wtsi HOM E9.5 0.00
abnormal heart morphology Ints10tm1b(KOMP)Wtsi HOM E9.5 0.00
abnormal neural tube closure Ints10tm1b(KOMP)Wtsi HET E9.5 0.00
abnormal embryo turning Ints10tm1b(KOMP)Wtsi HET E9.5 0.00
abnormal chorioallantoic fusion Ints10tm1b(KOMP)Wtsi HOM E9.5 0.00
persistence of hyaloid vascular system Ints10tm1b(KOMP)Wtsi HET Early adult 6.40×10-05
embryonic growth retardation Ints10tm1b(KOMP)Wtsi HET E9.5 0.00
abnormal neural tube closure Ints10tm1b(KOMP)Wtsi HOM E9.5 0.00
abnormal embryo size Ints10tm1b(KOMP)Wtsi HOM E9.5 0.00
abnormal embryo size Ints10tm1b(KOMP)Wtsi HET E12.5 0.00
embryonic growth retardation Ints10tm1b(KOMP)Wtsi HOM E9.5 0.00
impaired pupillary reflex Ints10tm1b(KOMP)Wtsi HET Early adult 1.57×10-10

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 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584)  (2/2)  Section images
Aorta 2 No  (2/2)  Section images
Brain 2 No  (2/2)  Section images
Brainstem 2 No  (2/2)  Section images
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No  (2/2)  Section images
Cerebellum 2 No  (2/2)  Section images
Cerebral cortex 2 No  (2/2)  Section images
Epididymis 2 No  (18/134)  (1/2)  Section images
Esophagus 2 No  (7/415)  (2/2)  Section images
Eye 2 No  (2/2)  Section images
Heart 2 No  (2/2)  Section images
Hippocampus 2 No  (2/2)  Section images
Hypothalamus 2 No  (2/2)  Section images
Kidney 2 No  (18/584)  (2/2)  Section images
Large intestine 2 No  (10/584) N/A
Liver 2 No N/A
Lower urinary tract 2 No N/A
Lung 2 No  (2/2)  Section images
Lymph node 2 No N/A
Mammary gland 2 No N/A
Midbrain 2 No  (2/2)  Section images
Olfactory lobe 2 No  (2/2)  Section images
Ovary 2 No  (1/584)  (1/2)  Section images
Oviduct 2 No  (1/2)  Section images
Pancreas 2 No  (5/584)  (2/2)  Section images
Peripheral nervous system 2 No  (2/2)  Section images
Peyer's patch 2 No N/A
Pituitary gland 2 No  (1/2)  Section images
Prostate gland 2 No  (12/584) N/A
Skeletal muscle 2 No  (2/2)  Section images
Skin 2 No N/A
Small intestine 2 No  (9/584)  (2/2)  Section images
Spinal cord 2 No  (2/2)  Section images
Spleen 2 No  (2/584)  (2/2)  Section images
Stomach 2 No  (12/584)  (2/2)  Section images
Striatum 2 No  (2/2)  Section images
Submandibular gland 2 No  (2/132)  Section images
Testis 2 No  (2/584)  (1/2)  Section images
Thalamus 2 No  (2/2)  Section images
Thymus 2 No  (2/2)  Section images
Thyroid gland 2 No  (15/584) N/A
Trachea 2 No  (2/2)  Section images
Urinary bladder 2 No  (2/2)  Section images
Uterus 2 No  (1/2)  Section images
Vascular system 2 No  (2/2)  Section images
Vesicular gland 2 No N/A
White adipose tissue 2 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2  (6/504)  (2/2) N/A
Dorsal root ganglion 2  (1/57) Image Only N/A
Ear 2  (1/504)  (2/2) N/A
Embryo 2  (1/505)  (2/2)  Wholemount images
Eye 2  (1/504)  (2/2) N/A
Foot 2  (1/504)  (2/2) N/A
Forebrain 2  (1/504)  (2/2) N/A
Forelimb 2  (1/504)  (2/2) N/A
Fronto-nasal process 2  (1/58)  (2/2) N/A
Hand 2  (1/503)  (2/2) N/A
Head 2  (5/504)  (2/2) N/A
Heart 2  (1/504)  (2/2) N/A
Hindbrain 2  (6/504)  (2/2) N/A
Hindlimb 2  (1/503)  (2/2) N/A
Liver 2  (1/504) N/A
Lung 2  (1/500) Image Only N/A
Mandibular process 2  (1/504)  (2/2) N/A
Maxillary process 2  (1/504)  (2/2) N/A
Midbrain 2  (1/504)  (2/2) N/A
Nose 2  (1/70)  (2/2) N/A
Oral cavity 2  (1/504) Image Only N/A
Skin 2  (1/504)  (2/2) N/A
Spinal cord 2  (1/69)  (2/2) N/A
Tail 2  (1/504)  (2/2) N/A
Tail somite 2  (1/504) Image Only N/A

 Associated Images

X-ray: XRay Images Whole Body Dorso Ventral
8 Images
X-ray: XRay Images Forepaw
8 Images
Original Image
Adult LacZ: LacZ Images Section
36 Images
X-ray: XRay Images Whole Body Lateral Orientation
8 Images
X-ray: XRay Images Skull Lateral Orientation
8 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
8 Images
Embryo LacZ: LacZ images wholemount
8 Images
Gross Morphology Embryo E9.5
7 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Ints10tm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre) Mice
Ints10tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Ints10tm3a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells
Ints10tm42337(L1L2_Pgk_PM) Targeting vectors

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