Zmynd8 | zinc finger, MYND-type containing 8

GeneMGI:1918025Synonyms: Prkcbp1, 3632413B07Rik, +4 more

Physiological systems

20 / 24 physiological systems tested

5 Significantly impacted by the knock-out

 Homeostasis/metabolism Growth/size/body region Hematopoietic system Cardiovascular system Mortality/aging

15 No significant impact

4 Not tested

Gene metrics:7Significant phenotypes
0Associated diseases
Expression examined in:45Adult tissues
0Embryo tissues

Phenotypes

preweaning lethality, complete penetrance1 supporting datasetZmynd8tm1a(EUCOMM)WtsihomozygoteEarly adultN/A * 
decreased circulating magnesium level1 supporting datasetZmynd8tm1a(EUCOMM)WtsiheterozygoteEarly adult1.14x10-5 
increased heart weight1 supporting datasetZmynd8tm1a(EUCOMM)WtsiheterozygoteEarly adult6.9x10-5 
decreased mean corpuscular volume1 supporting datasetZmynd8tm1a(EUCOMM)WtsiheterozygoteEarly adult1.73x10-5 
thrombocytosis1 supporting datasetZmynd8tm1a(EUCOMM)WtsiheterozygoteEarly adult1.52x10-5 
decreased body weight2 supporting datasetsZmynd8tm1a(EUCOMM)WtsiheterozygoteEarly adult6.93x10-10 
decreased mean corpuscular hemoglobin1 supporting datasetZmynd8tm1a(EUCOMM)WtsiheterozygoteEarly adult1.94x10-6 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Zmynd8tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Zmynd8tm1e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell

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