Not currently registered for phenotyping at IMPC
Phenotyping is currently not planned for a knockout strain of this gene.
Gene Summary
IMPC Data Collections
- No Body Weight Data
- No Embryo Imaging Data
- No Viability Data
Phenotyping is currently not planned for a knockout strain of this gene.
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
The table below shows human diseases predicted to be associated to Tspan2 by phenotypic similarity.
Disease | Similarity of phenotypes |
Matching phenotypes | Source |
---|---|---|---|
Focal Cortical Dysplasia, Type Ii | Astrocytosis | OMIM:607341 | |
Neutropenia-Monocytopenia-Deafness Syndrome | Abnormality of neutrophils, Abnormal macrophage morphology | ORPHA:2690 | |
Progressive Non-Fluent Aphasia | Astrocytosis | ORPHA:100070 | |
Frontotemporal Dementia And/Or Amyotrophic Lateral Sclerosis 7 | Astrocytosis | OMIM:600795 | |
Sporadic Creutzfeldt-Jakob Disease | Astrocytosis, Gliosis | ORPHA:204 | |
Familial Infantile Bilateral Striatal Necrosis | Astrocytosis, Basal ganglia gliosis | ORPHA:225154 | |
Behavioral Variant Of Frontotemporal Dementia | Astrocytosis | ORPHA:275864 | |
Polyhydramnios, Megalencephaly, And Symptomatic Epilepsy | Astrocytosis | OMIM:611087 | |
Inherited Creutzfeldt-Jakob Disease | Astrocytosis | ORPHA:282166 | |
Cirrhosis-Dystonia-Polycythemia-Hypermanganesemia Syndrome | Splenomegaly, Astrocytosis, Polycythemia | ORPHA:309854 | |
Laminin Subunit Alpha 2-Related Congenital Muscular Dystrophy | Astrocytosis | ORPHA:258 | |
Mitochondrial Dna Depletion Syndrome 4A (Alpers Type) | Astrocytosis, Gliosis | OMIM:203700 | |
Supranuclear Palsy, Progressive, 1 | Astrocytosis, Gliosis | OMIM:601104 | |
Cockayne Syndrome Type 3 | Astrocytosis, Splenomegaly | ORPHA:90324 |
Get highlights of the most important data releases, news and events, delivered straight to your email inbox
Subscribe to newsletter