Gene: Medag

Name
mesenteric estrogen dependent adipogenesis
MGI ID
MGI:1917967
Synonyms
MEDA-4 6330406I15Rik
Viability
Homozygous - Viable
Other links
Significant phenotypes (0) All measurements (540) Expression & images (45) Disease models (0) Order (4)
View data by physiological system
Significant
Not Significant
Not tested

Filtered by: all phenotypes

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Allele Center Procedure / Parameter Zygosity Mutants Statistical
Method
P Value Status
Medagtm2b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Total T cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Forepaw footpad size HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Medagtm2b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Effector gd cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Eye Morphology / Bulging eye HOM 7f:7m Fisher Exact Test framework 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / External genitalia morphology HOM 7f:7m Fisher Exact Test framework 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Total CD4+ NKT cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / B cell number HOM 7f:7m 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / NKT cell number HOM 7f:7m 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Bone marrow immunophenotyping / Pre-pro B cells (Hardy fraction A) - % of B220+ HOM 6f:6m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Spleen Immunophenotyping / KLRG1+ Treg cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Eye Morphology / Iris/Pupil HOM 7f:7m Fisher Exact Test framework 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Snout morphology HOM 7f:7m Fisher Exact Test framework 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Hematology / Mean cell hemoglobin concentration HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.480 Success
Medagtm2b(KOMP)Wtsi WTSI X-ray / Kyphosis HOM 7f:7m Fisher Exact Test framework 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI X-ray / Lumbar processes HOM 7f:7m Fisher Exact Test framework 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Incisors morphology HOM 7f:7m Fisher Exact Test framework 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Total B cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Indirect Calorimetry / Total food intake HOM 0f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.160 Success
Medagtm2b(KOMP)Wtsi WTSI X-ray / Fibula HOM 7f:7m Fisher Exact Test framework 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI X-ray / Shape of vertebrae HOM 7f:7m Fisher Exact Test framework 0.123 Success
Medagtm2b(KOMP)Wtsi WTSI Auditory Brain Stem Response / 6kHz-evoked ABR Threshold HOM 4f:0m 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Trunk curl HOM 7f:7m Fisher Exact Test framework 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Naive CD8+ T cells - % of CD8+ HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Effector gd T cells - % of gd T cells HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Body Composition (DEXA lean/fat) / Body length HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.337 Success
Medagtm2b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / KLRG1+ gd T cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Cortical Bone MicroCT / Cortical Bone Mineral Density HOM 2f:0m Not processed 1.00 FAILED - Not enough mutant or control data
Medagtm2b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Plasmacytoid DC - % of DC HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Eye Morphology / Lens Opacity HOM 7f:7m Fisher Exact Test framework 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Ly6C+ mature NK cells - % of mature NK cells HOM 0f:0m Manual Success
Medagtm2b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Limb skin appearance HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Medagtm2b(KOMP)Wtsi WTSI Clinical Chemistry / LDL-cholesterol HOM 7f:6m Mixed Model framework, linear mixed-effects model, equation withWeight 0.662 Success
Medagtm2b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Conventional DC (cDC) - % of CD45+ HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / Ly6Clow monocyte percentage HOM 7f:7m 0.309 Success
Medagtm2b(KOMP)Wtsi WTSI Vertebral Microradiography / Vertebral Height HOM 2f:0m Not processed 1.00 FAILED - Not enough mutant or control data
Medagtm2b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Follicular B cells - % of B2 cells HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Hindlimb size HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Medagtm2b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Forepaw morphology HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Medagtm2b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Effector CD4+ T helper cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Follicular B cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / KLRG1+ Treg cells - % of Treg HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI X-ray / Zygomatic bone HOM 7f:7m Fisher Exact Test framework 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Head skin colour HOM 7f:7m Fisher Exact Test framework 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Head coat/hair length HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Medagtm2b(KOMP)Wtsi WTSI Clinical Chemistry / Calcium HOM 7f:6m Mixed Model framework, linear mixed-effects model, equation withWeight 0.989 Success
Medagtm2b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Ventral coat/hair colour pattern HOM 7f:7m Fisher Exact Test framework 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Limb coat/hair length HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Medagtm2b(KOMP)Wtsi WTSI X-ray / Shape of ribs HOM 7f:7m Fisher Exact Test framework 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / CD4+ T helper cells - % of CD4+ HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Grip Strength / Forelimb and hindlimb grip strength normalised against body weight HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.712 Success
Medagtm2b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Macrophages - % of CD45+ HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Intraperitoneal glucose tolerance test (IPGTT) / Area under glucose response curve HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.849 Success
Medagtm2b(KOMP)Wtsi WTSI Spleen Immunophenotyping / CD4+ T helper cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / CD4+ alpha beta T cell percentage HOM 7f:7m 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Tail length HOM 7f:7m Fisher Exact Test framework 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / KLRG1+ CD4+ NKT cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Clinical Chemistry / Potassium HOM 7f:6m Mixed Model framework, linear mixed-effects model, equation withWeight 0.121 Success
Medagtm2b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Total CD4- NKT cells - % of NKT cells HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Bone marrow immunophenotyping / Myeloid cells - % of CD45+ HOM 6f:6m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Auditory Brain Stem Response / 30kHz-evoked ABR Threshold HOM 4f:0m 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Spleen Immunophenotyping / KLRG1+ CD4+ T helper cells - % of CD4+ T helper cells HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Total CD8+ T cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Clinical Chemistry / Phosphorus HOM 7f:6m Mixed Model framework, linear mixed-effects model, equation withWeight 0.990 Success
Medagtm2b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Germinal centre B cells - % of B2 cells HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Viability Primary Screen / Outcome HOM 61f:75m Supplied as data Success
Medagtm2b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / KLRG1+ CD4- NKT cells - % of CD4- NKT cells HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Plasmacytoid DC - % of DC HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Head bobbing/circling HOM 7f:7m Fisher Exact Test framework 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Forepaw nail colour HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Medagtm2b(KOMP)Wtsi WTSI Indirect Calorimetry / Respiratory Exchange Ratio HOM 0f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0652 Success
Medagtm2b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Digit coat/hair colour pattern HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Medagtm2b(KOMP)Wtsi WTSI Spleen Immunophenotyping / B1a cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Resting CD8+ T cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Eye Morphology / Corneal vascularization HOM 7f:7m Fisher Exact Test framework 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Eye Morphology / Retinal Blood Vessels Pattern HOM 7f:7m Fisher Exact Test framework 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Clinical Chemistry / Triglycerides HOM 7f:6m Mixed Model framework, linear mixed-effects model, equation withWeight 0.739 Success
Medagtm2b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Head size HOM 7f:7m Fisher Exact Test framework 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Hematology / Platelet count HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.548 Success
Medagtm2b(KOMP)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / CD4+ CD44+ CD62L- alpha beta effector T cell percentage HOM 7f:7m 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / External genitalia HOM 7f:7m Fisher Exact Test framework 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Resting gd T cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Resting CD4+ T helper cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Hindlimb morphology HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Medagtm2b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Follicular B cells - % of B2 cells HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Spleen Immunophenotyping / KLRG1+ CD4- NKT cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Transfer arousal HOM 7f:7m Fisher Exact Test framework 0.215 Success
Medagtm2b(KOMP)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / CD8+ KLRG1+ alpha beta T cell number HOM 7f:7m 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / Gamma delta T cell number HOM 7f:7m 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Eye Morphology / Pupil Position HOM 7f:7m Fisher Exact Test framework 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Limb skin colour HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Medagtm2b(KOMP)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / CD8+ CD44+ CD62L- alpha beta effector T cell percentage HOM 7f:7m 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Ear epidermis immunophenotyping / Average volume of LC HOM 2f:2m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Spleen Immunophenotyping / KLRG1+ CD8+ T cells - % of CD8+ HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI X-ray / Scoliosis HOM 7f:7m Fisher Exact Test framework 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Incisor colour HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Medagtm2b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Plasmacytoid DC - % of CD45+ HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / Neutrophil percentage HOM 7f:7m 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Early germinal centre B cells - % of CD45+ HOM 0f:0m Manual Success
Medagtm2b(KOMP)Wtsi WTSI X-ray / Fusion of vertebrae HOM 7f:7m Fisher Exact Test framework 0.0635 Success
Medagtm2b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Conventional DC (cDC) - % of CD45+ HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI X-ray / Tibia HOM 7f:7m Fisher Exact Test framework 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / CD5+ gd T cells - % of gd T cells HOM 0f:0m Manual Success
Medagtm2b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Head skin appearance HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Medagtm2b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Resting Treg cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Grip Strength / Forelimb and hindlimb grip strength measurement mean HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.793 Success
Medagtm2b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Paw footpad skin appearance HOM 7f:7m Fisher Exact Test framework 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Resting CD4+ NKT cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / CD8+ alpha beta T cell percentage HOM 7f:7m 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Total CD4+ T cells - % of ab T cells HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Digit coat/hair appearance HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Medagtm2b(KOMP)Wtsi WTSI Eye Morphology / Lens HOM 7f:7m Fisher Exact Test framework 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Resting gd T cells - % of gd T cells HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Grip Strength / Forelimb grip strength normalised against body weight HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.624 Success
Medagtm2b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Effector CD4+ T helper cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Spleen Immunophenotyping / CD11b-high cDC - % of CD45+ HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Tail morphology HOM 7f:7m Fisher Exact Test framework 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / KLRG1+ mature NK cell percentage HOM 7f:7m 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Resting CD4+ T helper cells - % of CD4+ T helper cells HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Clinical Chemistry / Sodium HOM 7f:6m Mixed Model framework, linear mixed-effects model, equation withWeight 0.189 Success
Medagtm2b(KOMP)Wtsi WTSI Femoral Microradiography / Femur Length HOM 2f:0m Not processed 1.00 FAILED - Not enough mutant or control data
Medagtm2b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Ventral coat/hair colour HOM 7f:7m Fisher Exact Test framework 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Total B cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Germinal centre B cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Body Composition (DEXA lean/fat) / Bone Mineral Content (excluding skull) HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0183 Success
Medagtm2b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Ly6C+ NKT cells - % of NKT cells HOM 0f:0m Manual Success
Medagtm2b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Corneal touch reflex HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Medagtm2b(KOMP)Wtsi WTSI Spleen Immunophenotyping / CD11b-low cDC - % of CD45+ HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Contact righting reflex HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Medagtm2b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Forepaw nail morphology HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Medagtm2b(KOMP)Wtsi WTSI Clinical Chemistry / HDL-cholesterol HOM 7f:6m Mixed Model framework, linear mixed-effects model, equation withWeight 0.456 Success
Medagtm2b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Effector CD8+ T cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Eye Morphology / Persistence of hyaloid vascular system HOM 7f:7m Fisher Exact Test framework 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Effector NK cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Vertebra Compression / Vertebra Yield Load HOM 2f:0m Not processed 1.00 FAILED - Not enough mutant or control data
Medagtm2b(KOMP)Wtsi WTSI Bone marrow immunophenotyping / Granulocytes - % of CD45+ HOM 6f:6m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI X-ray / Maxilla/Pre-maxilla HOM 7f:7m Fisher Exact Test framework 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Mature NK cells - % of NK cellls HOM 0f:0m Manual Success
Medagtm2b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Gait (inc. ataxia) HOM 7f:7m Fisher Exact Test framework 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Effector CD4- NKT cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Tail coat/hair appearance HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Medagtm2b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Naive CD8+ T cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Resting NK cells - % of NK cells HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI X-ray / Caudal processes HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Medagtm2b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Ventral skin appearance HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Medagtm2b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Hindlimb HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Medagtm2b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Total B2 cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Head morphology HOM 7f:7m Fisher Exact Test framework 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Dorsal coat/hair colour HOM 7f:7m Fisher Exact Test framework 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI X-ray / Number of ribs right HOM 7f:7m 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Resting CD4+ NKT cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Total DC - % of CD45+ HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / CD4+ CD25+ alpha beta regulatory T cell percentage HOM 7f:7m 0.345 Success
Medagtm2b(KOMP)Wtsi WTSI Clinical Chemistry / Alpha-amylase HOM 7f:6m Mixed Model framework, linear mixed-effects model, equation withWeight 0.613 Success
Medagtm2b(KOMP)Wtsi WTSI Spleen Immunophenotyping / KLRG1+ gd T cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Clinical Chemistry / Iron HOM 7f:6m Mixed Model framework, linear mixed-effects model, equation withWeight 0.232 Success
Medagtm2b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Resting Treg cells - % of Treg HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Resting CD4- NKT cells - % of CD4- NKT cells HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / KLRG1+ CD4+ T helper cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Transitional 1 B cells - % of B2 cells HOM 0f:0m Manual Success
Medagtm2b(KOMP)Wtsi WTSI Clinical Chemistry / Magnesium HOM 7f:6m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0106 Success
Medagtm2b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Convulsions HOM 7f:7m Fisher Exact Test framework 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Plasmacytoid DC - % of CD45+ HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Forepaw digit size HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Medagtm2b(KOMP)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / Monocyte number HOM 7f:7m 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Effector CD4+ T helper cells - % of CD4+ T helper cells HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Salmonella Challenge / Pre-Day 14 Death HOM 4f:0m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Medagtm2b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Hindpaw digit fusion HOM 7f:7m Fisher Exact Test framework 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Effector Treg cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Ear epidermis immunophenotyping / Average branch length of LC HOM 2f:2m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Spleen Immunophenotyping / CD103+ CD11b-low cDC - % of CD45+ HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Effector NK cells - % of NK cells HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Tail HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Medagtm2b(KOMP)Wtsi WTSI Grip Strength / Forelimb grip strength measurement mean HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.903 Success
Medagtm2b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Resting Treg cells - % of Treg HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Ventral coat/hair appearance HOM 7f:7m Fisher Exact Test framework 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Three-point Bend / Energy Dissipated Prior to Fracture HOM 2f:0m Not processed 1.00 FAILED - Not enough mutant or control data
Medagtm2b(KOMP)Wtsi WTSI DSS Histology / Pre-Day 10 Death HOM 2f:2m - 1.00 FAILED - Not enough mutant or control data
Medagtm2b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Limb coat/hair appearance HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Medagtm2b(KOMP)Wtsi WTSI X-ray / Femur HOM 7f:7m Fisher Exact Test framework 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / Eosinophil number HOM 7f:7m 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Pinna HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Medagtm2b(KOMP)Wtsi WTSI Eye Morphology / Cornea HOM 7f:7m Fisher Exact Test framework 0.467 Success
Medagtm2b(KOMP)Wtsi WTSI Clinical Chemistry / Free fatty acids HOM 7f:6m Mixed Model framework, linear mixed-effects model, equation withWeight 0.525 Success
Medagtm2b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Resting CD4+ T helper cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Germinal centre B cells - % of B2 cells HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Effector CD4+ T helper cells - % of CD4+ T helper cells HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Resting CD4+ NKT cells - % of CD4+ NKT cells HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Auditory Brain Stem Response / 12kHz-evoked ABR Threshold HOM 4f:0m 0.446 Success
Medagtm2b(KOMP)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / Eosinophil percentage HOM 7f:7m 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Resting CD8+ T cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Bone marrow immunophenotyping / Immature B cells (Hardy fraction E) - % of B220+ HOM 6f:6m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Body Composition (DEXA lean/fat) / Bone Mineral Density (excluding skull) HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0462 Success
Medagtm2b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Follicular B cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Pinna position HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Medagtm2b(KOMP)Wtsi WTSI Hematology / Red blood cell count HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.244 Success
Medagtm2b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Paw coat/hair colour HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Medagtm2b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Hindpaw digit count HOM 7f:7m Fisher Exact Test framework 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Resting gd T cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Eye Morphology / Iris Pigmentation HOM 7f:7m Fisher Exact Test framework 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Mature NK cells - % of lymphocytes HOM 0f:0m Manual Success
Medagtm2b(KOMP)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / CD4+ KLRG1+ alpha beta T cell percentage HOM 7f:7m 0.0509 Success
Medagtm2b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Paw footpad skin colour HOM 7f:7m Fisher Exact Test framework 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / CD11b-high cDC - % of cDC HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Granulocytes - % of CD45+ HOM 0f:0m Manual Success
Medagtm2b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Startle response HOM 7f:7m Fisher Exact Test framework 0.00185 Success
Medagtm2b(KOMP)Wtsi WTSI X-ray / Thoracic processes HOM 7f:7m Fisher Exact Test framework 0.386 Success
Medagtm2b(KOMP)Wtsi WTSI X-ray / Humerus HOM 7f:7m Fisher Exact Test framework 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Effector CD8+ T cells - % of CD8+ HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Effector CD4+ NKT cells - % of CD4+ NKT cells HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / NK cell number HOM 7f:7m 0.316 Success
Medagtm2b(KOMP)Wtsi WTSI Bone marrow immunophenotyping / Total B cells - % of CD45+ HOM 6f:6m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Clinical Chemistry / Urea (Blood Urea Nitrogen - BUN) HOM 7f:6m Mixed Model framework, linear mixed-effects model, equation withWeight 0.395 Success
Medagtm2b(KOMP)Wtsi WTSI Spleen Immunophenotyping / CD5+ gd T cells - % of gd T cells HOM 0f:0m Manual Success
Medagtm2b(KOMP)Wtsi WTSI X-ray / Number of lumbar vertebrae HOM 7f:7m 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI X-ray / Lordosis HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Medagtm2b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Ventral skin colour HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Medagtm2b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Eosinophils - % of CD45+ HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Effector CD4+ NKT cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Memory B cells - % of B2 cells HOM 0f:0m Manual Success
Medagtm2b(KOMP)Wtsi WTSI X-ray / Ulna HOM 7f:7m Fisher Exact Test framework 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI X-ray / Sacral processes HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Medagtm2b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Resting CD4- NKT cells - % of CD4- NKT cells HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Tail coat/hair length HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Medagtm2b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Effector Treg cells - % of Treg HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / KLRG1+ CD8+ T cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Forepaw digit count HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Medagtm2b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Total DC - % of CD45+ HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / External genitalia size HOM 7f:7m Fisher Exact Test framework 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Digit coat/hair presence HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Medagtm2b(KOMP)Wtsi WTSI X-ray / Number of caudal vertebrae HOM 7f:7m 0.103 Success
Medagtm2b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / KLRG1+ NK cells - % of NK cells HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / NK cell percentage HOM 7f:7m 0.0548 Success
Medagtm2b(KOMP)Wtsi WTSI X-ray / Number of ribs left HOM 7f:7m 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Memory B cells - % of CD45+ HOM 0f:0m Manual Success
Medagtm2b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Hindpaw nail colour HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Medagtm2b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Ventral coat/hair length HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Medagtm2b(KOMP)Wtsi WTSI Body Composition (DEXA lean/fat) / Bone Area HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.249 Success
Medagtm2b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Total NK cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Total CD4+ T cells - % of ab T cells HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Transitional 2 B cells - % of B2 cells HOM 0f:0m Manual Success
Medagtm2b(KOMP)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / IgD+ mature B cell number HOM 7f:7m 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Ear epidermis immunophenotyping / Average roundness of LC HOM 2f:2m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Total CD4- NKT cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Hindpaw digit morphology HOM 7f:7m Fisher Exact Test framework 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Resting CD4+ T helper cells - % of CD4+ T helper cells HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Tail skin colour HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Medagtm2b(KOMP)Wtsi WTSI Bone marrow immunophenotyping / Mature B cells (Hardy fraction F) - % of B220+ HOM 6f:6m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Dorsal coat/hair presence HOM 7f:7m Fisher Exact Test framework 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Paw coat/hair presence HOM 7f:7m Fisher Exact Test framework 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Pinna morphology HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Medagtm2b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Hindpaw digit size HOM 7f:7m Fisher Exact Test framework 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Transitional 2 B cells - % of CD45+ HOM 0f:0m Manual Success
Medagtm2b(KOMP)Wtsi WTSI Bone marrow immunophenotyping / Mature B cells (Hardy fraction F) - % of CD45+ HOM 6f:6m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / CD8+ KLRG1+ alpha beta T cell percentage HOM 7f:7m 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Spleen Immunophenotyping / KLRG1+ CD4+ T helper cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Clinical Chemistry / Glucose HOM 7f:6m Mixed Model framework, linear mixed-effects model, equation withWeight 0.570 Success
Medagtm2b(KOMP)Wtsi WTSI Spleen Immunophenotyping / KLRG1+ CD4+ NKT cells - % of CD4+ NKT cells HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Effector CD8+ T cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Fertility of Homozygous Knock-out Mice / Gross Findings Female HOM f:m Supplied as data Success
Medagtm2b(KOMP)Wtsi WTSI Bone marrow immunophenotyping / Pre-pro B cells (Hardy fraction A) - % of CD45+ HOM 6f:6m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI X-ray / Skull shape HOM 7f:7m Fisher Exact Test framework 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Total CD8+ T cells - % of ab T cells HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Forelimb HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Medagtm2b(KOMP)Wtsi WTSI Ear epidermis immunophenotyping / Langerhans cell (LC) count HOM 2f:2m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Digit coat/hair colour HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Medagtm2b(KOMP)Wtsi WTSI Clinical Chemistry / Chloride HOM 7f:6m Mixed Model framework, linear mixed-effects model, equation withWeight 0.313 Success
Medagtm2b(KOMP)Wtsi WTSI Insulin Blood Level / Insulin HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.355 Success
Medagtm2b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Ly6C+ mature NK cells - % of lymphocytes HOM 0f:0m Manual Success
Medagtm2b(KOMP)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / CD4+ CD25+ alpha beta regulatory T cell number HOM 7f:7m 0.327 Success
Medagtm2b(KOMP)Wtsi WTSI Body Composition (DEXA lean/fat) / Lean mass HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.245 Success
Medagtm2b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Effector CD4- NKT cells - % of CD4- NKT cells HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Eye Morphology / Pupil Light Response HOM 7f:7m Fisher Exact Test framework 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Eye Morphology / Corneal opacity HOM 7f:7m Fisher Exact Test framework 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / CD11b-low cDC - % of cDC HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Monocytes - % of CD45+ HOM 0f:0m Manual Success
Medagtm2b(KOMP)Wtsi WTSI X-ray / Number of pelvic vertebrae HOM 7f:7m 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI X-ray / Shape of ribcage HOM 7f:7m Fisher Exact Test framework 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Tremor HOM 7f:7m Fisher Exact Test framework 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Hematology / White blood cell count HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.000620 Success
Medagtm2b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Total CD4+ NKT cells - % of NKT cells HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Marginal zone B cells - % of B2 cells HOM 0f:0m Manual Success
Medagtm2b(KOMP)Wtsi WTSI Clinical Chemistry / Alanine aminotransferase HOM 7f:6m Mixed Model framework, linear mixed-effects model, equation withWeight 0.403 Success
Medagtm2b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Eosinophils - % of CD45+ HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Spleen Immunophenotyping / KLRG1+ NK cells - % of NK cells HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Plasma cells - % of CD45+ HOM 0f:0m Manual Success
Medagtm2b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Naive CD8+ T cells - % of CD8+ HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Clinical Chemistry / Creatinine HOM 7f:6m Mixed Model framework, linear mixed-effects model, equation withWeight 0.495 Success
Medagtm2b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Dorsal coat/hair appearance HOM 7f:7m Fisher Exact Test framework 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Marginal zone precursor B cells - % of CD45+ HOM 0f:0m Manual Success
Medagtm2b(KOMP)Wtsi WTSI X-ray / Number of thoracic vertebrae HOM 7f:7m 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Limb coat/hair colour HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Medagtm2b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / KLRG1+ CD4+ T helper cells - % of CD4+ T helper cells HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Spleen Immunophenotyping / KLRG1+ CD4- NKT cells - % of CD4- NKT cells HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Trabecular Bone MicroCT / Trabecular Thickness (mm) HOM 2f:0m Not processed 1.00 FAILED - Not enough mutant or control data
Medagtm2b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / B1a cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Memory B cells - % of CD45+ HOM 0f:0m Manual Success
Medagtm2b(KOMP)Wtsi WTSI X-ray / Radius HOM 7f:7m Fisher Exact Test framework 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Tail coat/hair colour HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Medagtm2b(KOMP)Wtsi WTSI Hematology / Mean platelet volume HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0821 Success
Medagtm2b(KOMP)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / NKT cell percentage HOM 7f:7m 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI X-ray / Brachydactyly HOM 7f:7m Fisher Exact Test framework 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Resting gd T cells - % of gd T cells HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Total gd T cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Tail skin appearance HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Medagtm2b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Hindpaw nail morphology HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Medagtm2b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Total CD4- NKT cells - % of NKT cells HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI X-ray / Scapulae HOM 7f:7m Fisher Exact Test framework 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / Alpha beta T cell number HOM 7f:7m 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Head coat/hair presence HOM 7f:7m Fisher Exact Test framework 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Spleen Immunophenotyping / CD4+ T helper cells - % of CD4+ HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Forepaw digit fusion HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Medagtm2b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Naive CD8+ T cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Plasma cells - % of B2 cells HOM 0f:0m Manual Success
Medagtm2b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Immature NK cells - % of lymphocytes HOM 0f:0m Manual Success
Medagtm2b(KOMP)Wtsi WTSI Eye Morphology / Retina (combined) HOM 7f:7m Not processed Success
Medagtm2b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Resting Treg cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Pinna size HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Medagtm2b(KOMP)Wtsi WTSI X-ray / Polysyndactylism HOM 7f:7m Fisher Exact Test framework 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Hematology / Hematocrit HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.163 Success
Medagtm2b(KOMP)Wtsi WTSI Antigen Specific Immunoglobulin Assay / TetC specific total IgG HOM 4f:0m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.492 Success
Medagtm2b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Memory B cells - % of B2 cells HOM 0f:0m Manual Success
Medagtm2b(KOMP)Wtsi WTSI Bone marrow immunophenotyping / Immature B cells (Hardy fraction E) - % of CD45+ HOM 6f:6m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Vibrissae shape HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Medagtm2b(KOMP)Wtsi WTSI Clinical Chemistry / Creatine kinase HOM 7f:6m Mixed Model framework, linear mixed-effects model, equation withWeight 0.962 Success
Medagtm2b(KOMP)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / Ly6Clow monocyte number HOM 7f:7m 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / CD4+ CD44+ CD62L- alpha beta effector T cell number HOM 7f:7m 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Total Treg cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Spleen Immunophenotyping / CD103+ CD11b-low cDC - % of CD11b-low cDC HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Eye Morphology / Pupil Dilation HOM 7f:7m Fisher Exact Test framework 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Bone marrow immunophenotyping / Pro-B cells (Hardy fraction C) - % of B220+ HOM 0f:0m Manual Success
Medagtm2b(KOMP)Wtsi WTSI Body Composition (DEXA lean/fat) / Fat mass HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.296 Success
Medagtm2b(KOMP)Wtsi WTSI Spleen Immunophenotyping / KLRG1+ CD4+ NKT cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / KLRG1+ mature NK cell number HOM 7f:7m 0.313 Success
Medagtm2b(KOMP)Wtsi WTSI Three-point Bend / Stiffness HOM 2f:0m Not processed 1.00 FAILED - Not enough mutant or control data
Medagtm2b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / KLRG1+ CD4- NKT cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Paw coat/hair appearance HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Medagtm2b(KOMP)Wtsi WTSI Clinical Chemistry / Thyroxine HOM 7f:6m Mixed Model framework, linear mixed-effects model, equation withWeight 0.307 Success
Medagtm2b(KOMP)Wtsi WTSI Spleen Immunophenotyping / KLRG1+ Treg cells - % of Treg HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Total Treg cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Transitional 1 B cells - % of CD45+ HOM 0f:0m Manual Success
Medagtm2b(KOMP)Wtsi WTSI Indirect Calorimetry / Total water intake HOM 0f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0653 Success
Medagtm2b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Forelimb size HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Medagtm2b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Dorsal skin colour HOM 7f:7m Fisher Exact Test framework 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Tail elevation HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Medagtm2b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Effector NK cells - % of NK cells HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Auditory Brain Stem Response / 18kHz-evoked ABR Threshold HOM 4f:0m 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Hindpaw morphology HOM 7f:7m Fisher Exact Test framework 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Total CD4- NKT cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / CD103+ CD11b-low cDC - % of CD11b-low cDC HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / B cell percentage HOM 7f:7m 0.0535 Success
Medagtm2b(KOMP)Wtsi WTSI X-ray / Clavicle HOM 7f:7m Fisher Exact Test framework 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Marginal zone B cells - % of CD45+ HOM 0f:0m Manual Success
Medagtm2b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Total Treg cells - % of CD4+ HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Trabecular Bone MicroCT / Trabecular Spacing (mm) HOM 2f:0m Not processed 1.00 FAILED - Not enough mutant or control data
Medagtm2b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Effector CD4- NKT cells - % of CD4- NKT cells HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Tail coat/hair colour pattern HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Medagtm2b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Late germinal centre B cells - % of GC cells HOM 0f:0m Manual Success
Medagtm2b(KOMP)Wtsi WTSI X-ray / Digit integrity HOM 7f:7m Fisher Exact Test framework 0.0475 Success
Medagtm2b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Resting CD4- NKT cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Marginal zone precursor B cells - % of B2 cells HOM 0f:0m Manual Success
Medagtm2b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Total CD4+ NKT cells - % of NKT cells HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Hindpaw nail length HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Medagtm2b(KOMP)Wtsi WTSI Clinical Chemistry / Total protein HOM 7f:6m Mixed Model framework, linear mixed-effects model, equation withWeight 0.689 Success
Medagtm2b(KOMP)Wtsi WTSI Body Composition (DEXA lean/fat) / Fat/Body weight HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.173 Success
Medagtm2b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Dorsal coat/hair colour pattern HOM 7f:7m Fisher Exact Test framework 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Effector gd T cells - % of gd T cells HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI X-ray / Number of cervical vertebrae HOM 7f:7m 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Total B2 cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Eye Morphology / Eyelid closure HOM 7f:7m Fisher Exact Test framework 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Head coat/hair colour HOM 7f:7m Fisher Exact Test framework 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Three-point Bend / Fracture Load HOM 2f:0m Not processed 1.00 FAILED - Not enough mutant or control data
Medagtm2b(KOMP)Wtsi WTSI Spleen Immunophenotyping / KLRG1+ CD8+ T cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / Ly6Chigh monocyte number HOM 7f:7m 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Limb coat/hair colour pattern HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Medagtm2b(KOMP)Wtsi WTSI Bone marrow immunophenotyping / Pre-B cells (Hardy fraction D) - % of CD45+ HOM 6f:6m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / Gamma delta T cell percentage HOM 7f:7m 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Clinical Chemistry / Aspartate aminotransferase HOM 7f:6m Mixed Model framework, linear mixed-effects model, equation withWeight 0.962 Success
Medagtm2b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Effector Treg cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Late germinal centre B cells - % of CD45+ HOM 0f:0m Manual Success
Medagtm2b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Forepaw digit morphology HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Medagtm2b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Resting NK cells - % of NK cells HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / CD5+ gd T cells - % of CD45+ HOM 0f:0m Manual Success
Medagtm2b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Ly6C+ immature NK cells - % of lymphocytes HOM 0f:0m Manual Success
Medagtm2b(KOMP)Wtsi WTSI Hematology / Hemoglobin HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.141 Success
Medagtm2b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Plasma cells - % of B2 cells HOM 0f:0m Manual Success
Medagtm2b(KOMP)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / Total T cell number HOM 7f:7m 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI X-ray / Syndactylism HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Medagtm2b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Ly6C+ NKT cells - % of lymphocytes HOM 0f:0m Manual Success
Medagtm2b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Total ab T cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Effector gd cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Forelimb morphology HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Medagtm2b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / CD103+ CD11b-low cDC - % of CD45+ HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Eye Morphology / Optic Disc HOM 7f:7m Fisher Exact Test framework 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Eye Morphology / Narrow eye opening HOM 7f:7m Fisher Exact Test framework 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Spleen Immunophenotyping / CD11b-low cDC - % of cDC HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Clinical Chemistry / Glycerol HOM 7f:6m Mixed Model framework, linear mixed-effects model, equation withWeight 0.350 Success
Medagtm2b(KOMP)Wtsi WTSI Heart Weight / Heart weight HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.530 Success
Medagtm2b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Vibrissae size HOM 7f:7m Fisher Exact Test framework 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Bone marrow immunophenotyping / Pre-B cells (Hardy fraction D) - % of B220+ HOM 6f:6m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Resting CD4+ NKT cells - % of CD4+ NKT cells HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Dorsal skin appearance HOM 7f:7m Fisher Exact Test framework 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Vibrissae colour HOM 7f:7m Fisher Exact Test framework 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / CD4+ KLRG1+ alpha beta T cell number HOM 7f:7m 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / IgD+ mature B cell percentage HOM 7f:7m 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Hindpaw footpad size HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Medagtm2b(KOMP)Wtsi WTSI Eye Morphology / Pupil Shape HOM 7f:7m Fisher Exact Test framework 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Fertility of Homozygous Knock-out Mice / Gross Findings Male HOM f:m Supplied as data Success
Medagtm2b(KOMP)Wtsi WTSI X-ray / Cervical processes HOM 7f:7m Fisher Exact Test framework 0.215 Success
Medagtm2b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Effector NK cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Total CD8+ T cells - % of ab T cells HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Effector CD4+ NKT cells - % of CD4+ NKT cells HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Total NK cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Monocytes - % of CD45+ HOM 0f:0m Manual Success
Medagtm2b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Resting CD8+ T cells - % of CD8+ HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Paw coat/hair colour pattern HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Medagtm2b(KOMP)Wtsi WTSI Three-point Bend / Yield Load HOM 2f:0m Not processed 1.00 FAILED - Not enough mutant or control data
Medagtm2b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Hindpaw nail count HOM 7f:7m Fisher Exact Test framework 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Cortical Bone MicroCT / Cortical Thickness HOM 2f:0m Not processed 1.00 FAILED - Not enough mutant or control data
Medagtm2b(KOMP)Wtsi WTSI Body Composition (DEXA lean/fat) / Lean/Body weight HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.261 Success
Medagtm2b(KOMP)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / CD8+ alpha beta T cell number HOM 7f:7m 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Bone marrow immunophenotyping / Plasma cells - % of CD45+ HOM 0f:0m Manual Success
Medagtm2b(KOMP)Wtsi WTSI Auditory Brain Stem Response / Click-evoked ABR threshold HOM 4f:0m 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Eye Morphology / Synechia HOM 7f:7m Fisher Exact Test framework 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Resting NK cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Auditory Brain Stem Response / 24kHz-evoked ABR Threshold HOM 4f:0m 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Clinical Chemistry / Total cholesterol HOM 7f:6m Mixed Model framework, linear mixed-effects model, equation withWeight 0.259 Success
Medagtm2b(KOMP)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / Monocyte percentage HOM 7f:7m 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Hindpaw HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Medagtm2b(KOMP)Wtsi WTSI Clinical Chemistry / Albumin HOM 7f:6m Mixed Model framework, linear mixed-effects model, equation withWeight 0.266 Success
Medagtm2b(KOMP)Wtsi WTSI Intraperitoneal glucose tolerance test (IPGTT) / Initial response to glucose challenge HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.390 Success
Medagtm2b(KOMP)Wtsi WTSI Antigen Specific Immunoglobulin Assay / TetC specific IgG1 HOM 4f:0m Mixed Model framework, generalized least squares, equation withoutWeight 0.0275 Success
Medagtm2b(KOMP)Wtsi WTSI X-ray / Transitional vertebrae HOM 7f:7m Fisher Exact Test framework 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Early germinal centre B cells - % of CD45+ HOM 0f:0m Manual Success
Medagtm2b(KOMP)Wtsi WTSI X-ray / Pelvis HOM 7f:7m Fisher Exact Test framework 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Late germinal centre B cells - % of CD45+ HOM 0f:0m Manual Success
Medagtm2b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Pinna rotation HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Medagtm2b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Total ab T cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Eye Morphology / Eyelid morphology HOM 7f:7m Fisher Exact Test framework 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI X-ray / Shape of spine HOM 7f:7m Fisher Exact Test framework 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Hematology / Mean cell volume HOM 7f:7m Not processed 1.00 FAILED - Insufficient variability in dependent variable 'IMPC_HEM_005_001' for MM/TF framework. Fisher Exact Test can be better way to do the analysis.
Medagtm2b(KOMP)Wtsi WTSI Bone marrow immunophenotyping / Pro-B cells (Hardy fraction C) - % of CD45+ HOM 0f:0m Manual Success
Medagtm2b(KOMP)Wtsi WTSI Vertebra Compression / Vertebra Max Load HOM 2f:0m Not processed 1.00 FAILED - Not enough mutant or control data
Medagtm2b(KOMP)Wtsi WTSI Femoral Microradiography / Femoral Bone Mineral Content HOM 2f:0m Not processed 1.00 FAILED - Not enough mutant or control data
Medagtm2b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / CD11b-low cDC - % of CD45+ HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Effector CD8+ T cells - % of CD8+ HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Spleen Immunophenotyping / CD11b-high cDC - % of cDC HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Total NKT cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Pinna skin colour HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Medagtm2b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / KLRG1+ gd T cells - % of gd T cells HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Positional passivity HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Medagtm2b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Head coat/hair colour pattern HOM 7f:7m Fisher Exact Test framework 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Forepaw nail length HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Medagtm2b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Forepaw HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Medagtm2b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Digit coat/hair length HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Medagtm2b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Macrophages - % of CD45+ HOM 1f:1m Manual 1.00 Not processed - Data analysis pending
Medagtm2b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Total CD4+ T cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Eye Morphology / Retinal Blood Vessels HOM 7f:7m Fisher Exact Test framework 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Resting CD4- NKT cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Trabecular Bone MicroCT / Trabecular Number (mm-1) HOM 2f:0m Not processed 1.00 FAILED - Not enough mutant or control data
Medagtm2b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Early germinal centre B cells - % of GC cells HOM 0f:0m Manual Success
Medagtm2b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Total gd T cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Total CD8+ T cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / KLRG1+ CD4+ NKT cells - % of CD4+ NKT cells HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Vibrissae HOM 7f:7m Fisher Exact Test framework 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI X-ray / Mandibles HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Medagtm2b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Pinna touch reflex HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Medagtm2b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Ventral coat/hair presence HOM 7f:7m Fisher Exact Test framework 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Ly6C+ immature NK cells - % of immature NK cells HOM 0f:0m Manual Success
Medagtm2b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Effector Treg cells - % of Treg HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Mouth morphology HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Medagtm2b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Granulocytes - % of CD45+ HOM 0f:0m Manual Success
Medagtm2b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Effector CD4+ NKT cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI X-ray / Number of digits HOM 7f:7m 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Anti-nuclear antibody assay / ANA score HOM 0f:3m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Anti-nuclear antibody assay / ANA score HOM 4f:0m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / Total T cell percentage HOM 7f:7m 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Resting NK cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / KLRG1+ CD8+ T cells - % of CD8+ HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / Ly6Chigh monocyte percentage HOM 7f:7m 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Limb coat/hair presence HOM 7f:7m Fisher Exact Test framework 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI DSS Histology / Average histology score HOM 2f:2m Not processed 1.00 FAILED - Not enough mutant or control data
Medagtm2b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Incisors HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Medagtm2b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / KLRG1+ NK cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Bone marrow immunophenotyping / Pro-B cells (Hardy fraction B) - % of CD45+ HOM 0f:0m Manual Success
Medagtm2b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Hindpaw size HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Medagtm2b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Plasma cells - % of CD45+ HOM 0f:0m Manual Success
Medagtm2b(KOMP)Wtsi WTSI Vertebral Microradiography / Vertebral Bone Mineral Content HOM 2f:0m Not processed 1.00 FAILED - Not enough mutant or control data
Medagtm2b(KOMP)Wtsi WTSI Clinical Chemistry / Fructosamine HOM 7f:6m Mixed Model framework, linear mixed-effects model, equation withWeight 0.969 Success
Medagtm2b(KOMP)Wtsi WTSI Anti-nuclear antibody assay / ANA classification HOM 0f:3m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Anti-nuclear antibody assay / ANA classification HOM 4f:0m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Clinical Chemistry / Alkaline phosphatase HOM 7f:6m Mixed Model framework, linear mixed-effects model, equation withWeight 0.862 Success
Medagtm2b(KOMP)Wtsi WTSI Eye Morphology / Eye Hemorrhage or Blood Presence HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Medagtm2b(KOMP)Wtsi WTSI X-ray / Teeth HOM 7f:7m Fisher Exact Test framework 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Paw coat/hair length HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Medagtm2b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Immature NK cells - % of NK cells HOM 0f:0m Manual Success
Medagtm2b(KOMP)Wtsi WTSI Cortical Bone MicroCT / Internal Diameter HOM 2f:0m Not processed 1.00 FAILED - Not enough mutant or control data
Medagtm2b(KOMP)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / CD4+ alpha beta T cell number HOM 7f:7m 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / CD4+ T helper cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Total NKT cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Antigen Specific Immunoglobulin Assay / TetC specific IgG2 HOM 4f:0m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.00253 Success
Medagtm2b(KOMP)Wtsi WTSI Eye Morphology / Fusion between cornea and lens HOM 7f:7m Fisher Exact Test framework 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Hematology / Mean corpuscular hemoglobin HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.627 Success
Medagtm2b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Tail coat/hair presence HOM 7f:7m Fisher Exact Test framework 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Total CD4+ T cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Forepaw size HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Medagtm2b(KOMP)Wtsi WTSI Spleen Immunophenotyping / KLRG1+ NK cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Intraperitoneal glucose tolerance test (IPGTT) / Fasted blood glucose concentration HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.218 Success
Medagtm2b(KOMP)Wtsi WTSI Clinical Chemistry / Total bilirubin HOM 7f:6m Mixed Model framework, linear mixed-effects model, equation withWeight 0.774 Success
Medagtm2b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Limb grasping HOM 7f:7m Fisher Exact Test framework 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Conventional DC (cDC) - % of DC HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Bone marrow immunophenotyping / T cells - % of CD45+ HOM 6f:6m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI X-ray / Fusion of ribs HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Medagtm2b(KOMP)Wtsi WTSI Body Composition (DEXA lean/fat) / BMC/Body weight HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0426 Success
Medagtm2b(KOMP)Wtsi WTSI Spleen Immunophenotyping / KLRG1+ gd T cells - % of gd T cells HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Head coat/hair appearance HOM 7f:7m Fisher Exact Test framework 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Forepaw nail count HOM 7f:7m Fisher Exact Test framework 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / Neutrophil number HOM 7f:7m 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Vertebra Compression / Vertebra Stiffness HOM 2f:0m Not processed 1.00 FAILED - Not enough mutant or control data
Medagtm2b(KOMP)Wtsi WTSI Eye Morphology / Retinal Blood Vessels Structure HOM 7f:7m Fisher Exact Test framework 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / CD11b-high cDC - % of CD45+ HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Germinal centre B cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / CD8+ CD44+ CD62L- alpha beta effector T cell number HOM 7f:7m 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI X-ray / Joints HOM 7f:7m Fisher Exact Test framework 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Resting CD8+ T cells - % of CD8+ HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / KLRG1+ Treg cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Pinna skin appearance HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Medagtm2b(KOMP)Wtsi WTSI X-ray / Fusion of processes HOM 7f:7m Fisher Exact Test framework 0.268 Success
Medagtm2b(KOMP)Wtsi WTSI Hematology / Red blood cell distribution width HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.000255 Success
Medagtm2b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Snout size HOM 7f:7m Fisher Exact Test framework 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Total CD4+ NKT cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / Alpha beta T cell percentage HOM 7f:7m 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Ear epidermis immunophenotyping / Average no of branches on LC HOM 2f:2m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Spleen Immunophenotyping / CD5+ gd T cells - % of CD45+ HOM 0f:0m Manual Success
Medagtm2b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Effector CD4- NKT cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Bone marrow immunophenotyping / Pro-B cells (Hardy fraction B) - % of B220+ HOM 0f:0m Manual Success
Medagtm2b(KOMP)Wtsi WTSI Three-point Bend / Max Load HOM 2f:0m Not processed 1.00 FAILED - Not enough mutant or control data
Medagtm2b(KOMP)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Total T cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Spleen Immunophenotyping / Total Treg cells - % of CD4+ HOM 4f:4m Manual 1.00 Success
Medagtm2b(KOMP)Wtsi WTSI Combined SHIRPA and Dysmorphology / Dorsal coat/hair length HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Medagtm2b(KOMP)Wtsi WTSI Trabecular Bone MicroCT / Bone Volume/Tissue Volume (%) HOM 2f:0m Not processed 1.00 FAILED - Not enough mutant or control data

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584) N/A
Aorta 2 No N/A
Blood vessel 2 No N/A
Bone 2 No N/A
Brain 2 No  (2/2) N/A
Brainstem 2 No  (2/2) N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No  (2/2) N/A
Cerebellum 2 No  (2/2) N/A
Cerebral cortex 2 No  (2/2) N/A
Eye 2 No N/A
Gall bladder 2 No N/A
Heart 2 No N/A
Hippocampus 2 No  (2/2) N/A
Hypothalamus 2 No  (2/2) N/A
Kidney 2 No  (18/584) N/A
Large intestine 2 No  (10/584) N/A
Liver 2 No N/A
Lower urinary tract 2 No N/A
Lung 2 No  (1/2) N/A
Lymph node 2 No N/A
Mammary gland 2 No N/A
Esophagus 2 No  (1/2) N/A
Olfactory lobe 2 No  (2/2) N/A
Ovary 2 No  (1/584) N/A
Oviduct 2 No N/A
Pancreas 2 No  (5/584) N/A
Parathyroid gland 2 No N/A
Peripheral nervous system 2 No  (2/2) N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No  (1/2) N/A
Prostate gland 2 No  (12/584) N/A
Skeletal muscle tissue 2 No N/A
Skin 2 No  (1/2) N/A
Small intestine 2 No  (9/584) N/A
Spinal cord 2 No  (2/2) N/A
Spleen 2 No  (2/584) N/A
Stomach 2 No  (12/584)  (1/2) N/A
Striatum 2 No N/A
Testis 2 No  (2/584) N/A
Thymus 2 No N/A
Thyroid gland 2 No  (15/584) N/A
Trachea 2 No  (1/2) N/A
Uterus 2 No N/A
White adipose tissue 2 No N/A
No Embryo expression data was found for this gene.

 Associated Images

X-ray: XRay Images Forepaw
14 Images
X-ray: XRay Images Lateral Orientation
28 Images
X-ray: XRay Images Dorso Ventral
43 Images
X-ray: XRay Images Skull Lateral Orientation
14 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
15 Images
Anti-nuclear antibody assay
7 Images
DSS Histology
8 Images

 Disease Models

No associations by disease annotation and gene orthology found.
Please visit the desktop version to see this section

 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Medagtm2a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Medagtm2b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre) Mice
Medagtm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells
Medagtm45160(L1L2_gt2) Targeting vectors

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