Bbx | bobby sox HMG box containing
Physiological systems
20 / 24 physiological systems tested
5 Significantly impacted by the knock-out
Adipose tissue Growth/size/body region Behavior/neurological Skeleton Craniofacial
15 No significant impact
4 Not tested
Data collections
Gene metrics:7Significant phenotypes
0Associated diseases
Expression examined in:45Adult tissues
0Embryo tissues
decreased body length | 1 supporting dataset | Bbxtm1a(EUCOMM)Wtsi | homozygote | Early adult | 5.69x10-13 | ||
increased total body fat amount | 1 supporting dataset | Bbxtm1a(EUCOMM)Wtsi | homozygote | Early adult | 2.08x10-5 | ||
decreased body weight | 4 supporting datasets | Bbxtm1a(EUCOMM)Wtsi | homozygote | Early adult | 6.27x10-7 | ||
abnormal cranium morphology | 1 supporting dataset | Bbxtm1a(EUCOMM)Wtsi | homozygote | Early adult | 4.34x10-6 | ||
decreased lean body mass | 1 supporting dataset | Bbxtm1a(EUCOMM)Wtsi | homozygote | Early adult | 1.06x10-6 | ||
abnormal tooth morphology | 1 supporting dataset | Bbxtm1a(EUCOMM)Wtsi | homozygote | Early adult | 2.37x10-6 | ||
increased thermal nociceptive threshold | 1 supporting dataset | Bbxtm1a(EUCOMM)Wtsi | homozygote | Early adult | 2.07x10-10 |
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adrenal gland | heterozygote | n/a | 0% (0/2) | 0.7% (4/570) |
aorta | heterozygote | n/a | n/a | 0.19% (1/533) |
blood vessel | heterozygote | n/a | 0% (0/2) | 0% (0/173) |
bone | heterozygote | n/a | 0% (0/2) | 0% (0/394) |
brain | heterozygote | n/a | 100% (2/2) | 0.86% (5/579) |
brainstem | heterozygote | n/a | n/a | 0.41% (2/490) |
brown adipose tissue | heterozygote | n/a | 0% (0/2) | 0% (0/588) |
cartilage tissue | heterozygote | n/a | 100% (2/2) | 0.22% (1/454) |
cerebellum | heterozygote | n/a | n/a | 0.56% (3/532) |
cerebral cortex | heterozygote | n/a | n/a | 0.41% (2/491) |
This gene doesn't have any significant Histopathology hits. Click here to see the raw data
External links
No external links available for Bbx.
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Bbxtm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
Bbxtm1e(EUCOMM)Wtsi | Targeted, non-conditional allele | | ES Cell |