Gene: Bclaf1

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Name
BCL2-associated transcription factor 1
MGI ID
MGI:1917580
Synonyms
2700025J07Rik 2810454G14Rik 2610102K23Rik 5730534O06Rik
Viability
Embryo viewer
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
preweaning lethality, complete penetrance Bclaf1tm1b(EUCOMM)Wtsi HOM   Early adult 0.00
abnormal lens morphology Bclaf1tm1b(EUCOMM)Wtsi HET Early adult 1.36×10-05
cyanosis Bclaf1tm1b(EUCOMM)Wtsi HOM E18.5 0.00
decreased grip strength Bclaf1tm1b(EUCOMM)Wtsi HET   Early adult 7.61×10-05

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Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (4/583) N/A
Aorta 2 No  (1/583) N/A
Brain 2 No  (4/583) N/A
Brainstem 2 No  (2/583) N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No  (1/583) N/A
Cerebellum 2 No  (3/583) N/A
Cerebral cortex 2 No  (2/583) N/A
Epididymis 2 No  (18/132) N/A
Esophagus 2 No  (7/407) N/A
Eye 2 No N/A
Heart 2 No  (2/583) N/A
Hippocampus 2 No  (3/583) N/A
Hypothalamus 2 No  (2/583) N/A
Kidney 2 No  (21/583)  (2/2)  Section images
Large intestine 2 No  (10/583) N/A
Liver 2 No N/A
Lower urinary tract 2 No  (1/583) N/A
Lung 2 No  (2/583) N/A
Lymph node 2 No  (1/583) N/A
Mammary gland 2 No N/A
Midbrain 2 No N/A
Olfactory lobe 2 No  (2/583) N/A
Ovary 2 No  (1/583)  (1/2)  Section images
Oviduct 2 No N/A
Pancreas 2 No  (5/583) N/A
Peripheral nervous system 2 No  (2/583) N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No  (1/583) N/A
Prostate gland 2 No  (12/583) N/A
Skeletal muscle 2 No N/A
Skin 2 No  (1/583) N/A
Small intestine 2 No  (9/583) N/A
Spinal cord 2 No  (3/583) N/A
Spleen 2 No  (3/583) N/A
Stomach 2 No  (13/583) N/A
Striatum 2 No  (3/583) N/A
Submandibular gland 2 No  (2/130)  (2/2)  Section images
Testis 2 No  (6/583)  (1/2)  Section images
Thalamus 2 No N/A
Thymus 2 No  (1/583) N/A
Thyroid gland 2 No  (17/583) N/A
Trachea 2 No  (3/583)  (1/2)  Section images
Urinary bladder 2 No N/A
Uterus 2 No  Section images
Vascular system 2 No N/A
Vesicular gland 2 No N/A
White adipose tissue 2 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
2  (6/505) N/A
1  (1/60) N/A
2  (1/505) N/A
2  (1/506) N/A
2  (1/505) N/A
2  (1/505) N/A
2  (1/505) N/A
2  (1/505) N/A
1  (1/61) N/A
2  (1/505) N/A
2  (5/505) N/A
2  (1/505) N/A
2  (6/505) N/A
2  (1/505) N/A
2  (1/503) N/A
2  (1/503) N/A
2  (1/505) N/A
2  (1/505) N/A
2  (1/505) N/A
1  (1/75) N/A
2  (1/503) N/A
2  (1/505) N/A
1  (1/72) N/A
2  (1/505) N/A
2  (1/505) N/A

 Associated Images

X-ray: XRay Images Whole Body Lateral Orientation
11 Images
X-ray: XRay Images Skull Lateral Orientation
11 Images
Original Image
Adult LacZ: LacZ Images Section
6 Images
X-ray: XRay Images Forepaw
11 Images
X-ray: XRay Images Whole Body Dorso Ventral
11 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
11 Images
Combined SHIRPA and Dysmorphology
1 Images
Gross Morphology Embryo E18.5
4 Images
Sleep Wake: Wake state (bmp file)
2 Images
Auditory Brain Stem Response: Click-evoked + 6 to 30kHz tone waveforms (pdf format)
6 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Bclaf1tm1b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre) Mice
Bclaf1tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells

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