The IMPC applies a panel of phenotyping screens to characterise single-gene knockout mice by comparison to wild types. Click on the different tabs to visualise significant phenotypes identified by the IMPC, as well as all data that was measured.
|Phenotype||System||Allele||Zyg||Sex||Life Stage||P Value|
|hyperalgesia||Cnrip1em1(IMPC)Mbp||HOM||Early adult||9.41×10-05 *|
|decreased exploration in new environment||Cnrip1em1(IMPC)Mbp||HOM||Early adult||9.22×10-07|
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
The table below shows human diseases predicted to be associated to Cnrip1 by phenotypic similarity.
|Complex Regional Pain Syndrome||
|Anterior Cutaneous Nerve Entrapment Syndrome||
|Mitochondrial Dna Depletion Syndrome 1 (Mngie Type)||
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|MGI Allele||Allele Type||Produced|
|Cnrip1tm41844(L1L2_Bact_P)||KO first allele (reporter-tagged insertion with conditional potential)||Targeting vectors|
|Cnrip1em1(IMPC)Mbp||Exon Deletion||Mice, Tissue|
|Cnrip1tm41844(L1L2_gt2)||KO first allele (reporter-tagged insertion with conditional potential)||Targeting vectors|