Gene Summary

double PHD fingers 3
2810403B03Rik,  Gm18872,  CERD4,  cer-d4

IMPC Data Collections

IMPC Phenotype Summary

Not Significant
Not tested


The IMPC applies a panel of phenotyping screens to characterise single-gene knockout mice by comparison to wild types. Click on the different tabs to visualise significant phenotypes identified by the IMPC, as well as all data that was measured.

Phenotype System Allele Zyg Sex Life Stage P Value
decreased grip strength Dpf3em1(IMPC)J HOM Early adult 6.25×10-05
decreased bone mineral content Dpf3em1(IMPC)J HOM Early adult 1.06×10-10
decreased circulating calcium level Dpf3em1(IMPC)J HOM Early adult 1.61×10-05
decreased locomotor activity Dpf3em1(IMPC)J HOM Early adult 7.85×10-07
decreased prepulse inhibition Dpf3em1(IMPC)J HOM Early adult 2.72×10-07

Download data as:  TSV  XLS

Select physiological systems to view:
Viewing: all phenotypes
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Viewing: all phenotypes

lacZ Expression

Expression data not available

Associated Images

Images submitted by IMPC centres for a selection of procedures. Each set of images is available to view in our image comparator.


XRay Images Forepaw

12 Images

Electrocardiogram (ECG)

Waveform Image

16 Images


XRay Images Whole Body Dorso Ventral

12 Images


XRay Images Skull Lateral Orientation

12 Images


XRay Images Whole Body Lateral Orientation

12 Images


XRay Images Skull Dorso Ventral Orientation

12 Images

Electroretinography 3

Fundus file

4 Images

Auditory Brain Stem Response

Click-evoked + 6 to 30kHz tone waveforms (pdf format)

8 Images

Human diseases caused by Dpf3 mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.

No human diseases associated to this gene by orthology or annotation.

The table below shows human diseases predicted to be associated to Dpf3 by phenotypic similarity.

Disease Similarity of
Matching phenotypes Source
Hypoparathyroidism, Familial Isolated, 2
Hypocalcemia, Hyperphosphatemia, Hypocalcemic seizures OMIM:618883
Hypocalcemia, Autosomal Dominant 2
Hypocalcemia OMIM:615361
22q11 deletion syndrome (Velocardiofacial / DiGeorge syndrome)
Hypocalcemia DECIPHER:16
Myopathy, Tubular Aggregate, 2
Hypocalcemia, Elevated circulating creatine kinase concentration, Falls OMIM:615883
Hypomagnesemia 1, Intestinal
Hypomagnesemia, Hypocalcemia OMIM:602014
Pseudohypoparathyroidism Type 2
Hypocalcemic tetany, Hypocalcemia, Hyperphosphatemia, Hypocalcemic seizures ORPHA:94090
Vitamin D-Dependent Rickets, Type 3
Osteopenia, Hypophosphatemia, Hypocalcemia OMIM:619073
Pseudohypoparathyroidism, Type Ii
Hypocalcemia, Hyperphosphatemia OMIM:203330
Familial Isolated Hypoparathyroidism Due To Agenesis Of Parathyroid Gland
Hypomagnesemia, Hypocalcemia, Hyperphosphatemia, Hypocalcemic seizures ORPHA:2239
Progressive Familial Intrahepatic Cholestasis
Hypocalcemia, Reduced bone mineral density ORPHA:172
Autosomal Recessive Kenny-Caffey Syndrome
Cortical thickening of long bone diaphyses, Hypocalcemia, Hypocalcemic tetany, Calvarial osteoscl... ORPHA:93324
Hypocalcemic Vitamin D-Resistant Rickets
Bone cyst, Hypophosphatemia, Hypocalcemia, Osteomalacia, Abnormal bone structure, Gait disturbanc... ORPHA:93160
Renal Tubular Acidosis, Distal, 1
Elevated circulating creatinine concentration, Hypokalemia, Osteomalacia, Hypocalcemia OMIM:179800
Hypoparathyroidism, Familial Isolated, 1
Hypocalcemia, Hyperphosphatemia, Hypocalcemic seizures OMIM:146200
Cholestasis, Progressive Familial Intrahepatic, 7, With Or Without Hearing Loss
Hypocalcemia, Elevated circulating gamma-aminobutyric acid concentration OMIM:619658
Autosomal Dominant Hypophosphatemic Rickets
Hypophosphatemia, Osteomalacia, Rickets, Hypocalcemia ORPHA:89937
Pseudohypoparathyroidism, Type Ib
Hypocalcemia, Hyperphosphatemia OMIM:603233
Hyperparathyroidism 4
Osteopenia, Hypercalcemia OMIM:617343
Ulna Metaphyseal Dysplasia Syndrome
Hypercalcemia OMIM:191420
Autoimmune Hypoparathyroidism
Hypocalcemia, Increased bone mineral density, Hypocalcemic tetany, Hyperphosphatemia, Hypocalcemi... ORPHA:36913
Blue Diaper Syndrome
Hypercalcemia, Abnormal circulating tryptophan concentration OMIM:211000
Hypocalcemia, Autosomal Dominant 1
Hypomagnesemia, Hypokalemia, Hypocalcemia, Increased circulating renin level, Hyperphosphatemia OMIM:601198
Pseudohypoparathyroidism Type 1B
Hypocalcemia, Diaphyseal sclerosis, Increased bone mineral density, Hypocalcemic tetany, Hyperpho... ORPHA:94089
Lipodystrophy, Congenital Generalized, Type 3
Hypertriglyceridemia, Hypocalcemia, Hypercholesterolemia OMIM:612526
Hypercalcemia ORPHA:55881
Alpha-Heavy Chain Disease
Hypocalcemia ORPHA:100025
Hypocalcemic Vitamin D-Dependent Rickets
Delayed epiphyseal ossification, Sparse bone trabeculae, Hypophosphatemia, Hypocalcemia, Osteomal... ORPHA:289157
2P21 Microdeletion Syndrome
Hypocalcemia ORPHA:163693
Genetic Recurrent Myoglobinuria
Hypocalcemia, Difficulty walking, Hyperphosphatemia, Fatigable weakness of swallowing muscles, Hi... ORPHA:99845
Kenny-Caffey Syndrome, Type 1
Calvarial osteosclerosis, Hypomagnesemia, Hypocalcemia, Decreased skull ossification OMIM:244460
Brain Abnormalities, Neurodegeneration, And Dysosteosclerosis
Osteopetrosis, Ataxia, Hypocalcemia OMIM:618476
Refractory Celiac Disease
Hypomagnesemia, Hypophosphatemia, Hypocalcemia, Hypoproteinemia, Osteoporosis, Hypoalbuminemia ORPHA:398063
Hyperparathyroidism 1
Hypercalcemia OMIM:145000
Nephropathy-Deafness-Hyperparathyroidism Syndrome
Bone cyst, Hypercalcemia ORPHA:2668
Hypoparathyroidism-Retardation-Dysmorphism Syndrome
Patchy osteosclerosis, Hypocalcemia, Hyperphosphatemia, Hypocalcemic seizures OMIM:241410
Familial Isolated Hyperparathyroidism
Hypophosphatemia, Osteopenia, Generalized osteoporosis, Hypercalcemia, Infantile hypercalcemia ORPHA:99879
Albers-Sch├Ânberg Osteopetrosis
Generalized osteosclerosis, Hypocalcemia ORPHA:53
Oncogenic Osteomalacia
Gait disturbance, Hypophosphatemia, Fibrous dysplasia of the bones, Hypocalcemia ORPHA:352540
Tumoral Calcinosis, Hyperphosphatemic, Familial, 3
Osteopenia, Metacarpal periosteal thickening, Hyperphosphatemia, Hypercalcemia, Calvarial osteosc... OMIM:617994
Osteopetrosis, Autosomal Recessive 1
Hypocalcemia, Increased bone mineral density, Craniosynostosis, Osteopetrosis, Calvarial osteoscl... OMIM:259700
Timothy Syndrome
Hypocalcemia OMIM:601005
Oculocerebrodental Syndrome
Hypocalcemia, Hypercalcemia ORPHA:557003
Ring Chromosome 10 Syndrome
Hypocalcemia ORPHA:1438
Hypotonia-Cystinuria Syndrome
Hypocalcemia OMIM:606407
Familial Isolated Hypoparathyroidism
Hypocalcemia ORPHA:2238
Parathyroid Carcinoma
Hypercalcemia OMIM:608266
Polyposis, Skin Pigmentation, Alopecia, And Fingernail Changes
Hypomagnesemia, Hypokalemia, Hypocalcemia OMIM:175500
Autosomal Dominant Hypocalcemia
Hypomagnesemia, Hypocalcemia, Reduced bone mineral density, Fatigable weakness, Hyperphosphatemia ORPHA:428
Hypercalcemia, Infantile, 2
Hypophosphatemia, Hypercalcemia OMIM:616963
Hypokalemia, Hypocalcemia, Abnormal blood ion concentration, Hyponatremia, Lethargy ORPHA:173
Intrauterine Growth Retardation, Metaphyseal Dysplasia, Adrenal Hypoplasia Congenita, And Genital Anomalies
Osteopenia, Hypercalcemia, Craniosynostosis OMIM:614732
Hypervitaminosis A, Susceptibility To
Hypercalcemia OMIM:240150
Colchicine Poisoning
Hypomagnesemia, Hypophosphatemia, Hypokalemia, Hypocalcemia, Abnormal blood ion concentration, Hy... ORPHA:31824
Very Long Chain Acyl-Coa Dehydrogenase Deficiency
Hypocalcemia, Hypoproteinemia, Hyperammonemia, Elevated circulating creatine kinase concentration... ORPHA:26793
Gracile Bone Dysplasia
Hypocalcemia, Decreased skull ossification OMIM:602361
Kenny-Caffey Syndrome, Type 2
Hypocalcemia, Increased bone mineral density, Hyperphosphatemia, Transient hypophosphatemia, Thic... OMIM:127000
Granulomatous Slack Skin
Hypercalcemia ORPHA:33111
Sanjad-Sakati Syndrome
Patchy osteosclerosis, Hypocalcemia, Hyperphosphatemia ORPHA:2323
Pseudohypoparathyroidism Type 1A
Hypocalcemia, Increased bone mineral density, Reduced bone mineral density, Ectopic ossification,... ORPHA:79443
X-Linked Agammaglobulinemia
Hypocalcemia ORPHA:47
Mitochondrial Trifunctional Protein Deficiency
Lethargy, Hypocalcemia, Tip-toe gait ORPHA:746
Pseudohypoparathyroidism Type 1C
Hypocalcemia, Increased bone mineral density, Ectopic ossification, Hypocalcemic tetany, Hyperpho... ORPHA:79444
Celiac Disease, Susceptibility To, 1
Ataxia, Hypocalcemia, Osteoporosis, Rickets OMIM:212750
Dahlberg-Borer-Newcomer Syndrome
Hypocalcemia ORPHA:1563
Osteopetrosis, Autosomal Recessive 5
Hypocalcemia, Increased bone mineral density, Decreased osteoclast count, Hyperbilirubinemia, Ost... OMIM:259720
Congenital Disorder Of Glycosylation, Type Ig
Hypocalcemia OMIM:607143
Diarrhea 10, Protein-Losing Enteropathy Type
Hypomagnesemia, Hypocalcemia, Hypertriglyceridemia, Hypoalbuminemia, Hyponatremia OMIM:618183
Oculoskeletodental Syndrome
Hypocalcemia, Hypercalcemia OMIM:618440
Primary Intestinal Lymphangiectasia
Hypomagnesemia, Hypocalcemia, Hypoalbuminemia, Hypoproteinemia ORPHA:90362
Hypophosphatemic Rickets And Hyperparathyroidism
Hypophosphatemic rickets, Hypophosphatemia, Hypercalcemia, Rickets OMIM:612089
Pseudohypoparathyroidism, Type Ia
Hypocalcemic tetany, Hyperphosphatemia, Osteoporosis, Subcutaneous ossification OMIM:103580
Hypercalcemia, Infantile, 1
Infantile hypercalcemia, Lethargy OMIM:143880
Hypercalcemia, Craniosynostosis ORPHA:436
Pseudohypoparathyroidism, Type Ic
Hypocalcemic tetany, Hyperphosphatemia, Osteoporosis OMIM:612462
Neuroleptic Malignant Syndrome
Hypomagnesemia, Hypocalcemia, Elevated circulating creatine kinase concentration, Hypernatremia, ... ORPHA:94093
Infantile Myofibromatosis
Bone cyst, Osteolysis, Hypercalcemia ORPHA:2591
Blue Diaper Syndrome
Hyperphosphatemia, Hypercalcemia ORPHA:94086
Small Cell Carcinoma Of The Bladder
Hypercalcemia ORPHA:284400
Diffuse Neonatal Hemangiomatosis
Hypercalcemia ORPHA:2123
Mullerian Derivatives, Persistence Of, With Lymphangiectasia And Postaxial Polydactyly
Hypocalcemia, Hypoproteinemia OMIM:235255
Juvenile Nephropathic Cystinosis
Hypophosphatemia, Hypokalemia, Hypocalcemia, Hypocalcemic tetany, Elevated circulating creatinine... ORPHA:411634
Hyperparathyroidism, Neonatal Self-Limited Primary, With Hypercalciuria
Hypercalcemia OMIM:239199
Vitamin D Hydroxylation-Deficient Rickets, Type 1A
Delayed epiphyseal ossification, Sparse bone trabeculae, Hypophosphatemia, Thin bony cortex, Diff... OMIM:264700
Hypophosphatasia, Infantile
Craniosynostosis, Elevated plasma pyrophosphate, Decreased calvarial ossification, Hypercalcemia,... OMIM:241500
Fibrous Dysplasia Of Bone
Hypophosphatemia, Fibrous dysplasia of the bones, Osteomalacia, Antalgic gait, Thin bony cortex, ... ORPHA:249
Bacterial Toxic-Shock Syndrome
Elevated circulating creatinine concentration, Hypoalbuminemia, Elevated circulating creatine kin... ORPHA:36234
Double Outlet Right Ventricle
Hypocalcemia ORPHA:3426
Ethylene Glycol Poisoning
Ataxia, Hypocalcemia, Hyperkalemia ORPHA:31826
Visceral Steatosis, Congenital
Hypocalcemia, Lethargy OMIM:228100
Metaphyseal Chondrodysplasia, Jansen Type
Osteopenia, Hypophosphatemia, Waddling gait, Hypercalcemia OMIM:156400
Paget Disease Of Bone 2, Early-Onset
Osteosclerosis of the ulna, Sclerosis of skull base, Osteolysis, Hypercalcemia OMIM:602080
Rhabdoid Tumor
Hypercalcemia ORPHA:69077
Familial Hypocalciuric Hypercalcemia
Renal hypophosphatemia, Osteomalacia, Hypercalcemia, Hypermagnesemia, Infantile hypercalcemia, Hy... ORPHA:405
Immune Dysregulation-Polyendocrinopathy-Enteropathy-X-Linked Syndrome
Hypomagnesemia, Hypocalcemia, Decreased prealbumin level, Abnormal blood ion concentration, Hypoa... ORPHA:37042
Vitamin D-Dependent Rickets, Type 2A
Delayed epiphyseal ossification, Sparse bone trabeculae, Hypophosphatemia, Thin bony cortex, Diff... OMIM:277440
Kidney Tubulopathy-Dilated Cardiomyopathy Syndrome
Hypomagnesemia, Hypocalcemia, Hypocalcemic tetany ORPHA:73224
Cartilage-Hair Hypoplasia
Hypocalcemia, Abnormal bone ossification, Abnormally ossified vertebrae ORPHA:175
M├╝llerian Derivatives-Lymphangiectasia-Polydactyly Syndrome
Hypocalcemia, Hypoproteinemia ORPHA:1655
Hypocalciuric Hypercalcemia, Familial, Type Iii
Hypophosphatemia, Osteomalacia, Hypercalcemia, Hypermagnesemia OMIM:600740
Exercise-Induced Malignant Hyperthermia
Ataxia, Hypocalcemia, Elevated circulating creatine kinase concentration, Hyperphosphatemia, Hype... ORPHA:466650
Uremic Pruritus
Increased blood urea nitrogen, Hypercalcemia, Hypermagnesemia, Renal hypophosphatemia ORPHA:94059
Autosomal Recessive Malignant Osteopetrosis
Hypophosphatemia, Hypocalcemia, Reduced bone mineral density, Osteopetrosis, Craniosynostosis ORPHA:667
Rajab Interstitial Lung Disease With Brain Calcifications 1
Hypocalcemia, Reduced bone mineral density, Osteopenia, Thin bony cortex, Unconjugated hyperbilir... OMIM:613658
Hypocalciuric Hypercalcemia, Familial, Type I
Hypercalcemia, Hypermagnesemia OMIM:145980
Pearson Syndrome
Ataxia, Hypophosphatemia, Hypomagnesemia, Hypokalemia, Hypocalcemia, Hyperalaninemia ORPHA:699
Hyperparathyroidism 2 With Jaw Tumors
Hypercalcemia OMIM:145001
Non-Functioning Paraganglioma
Hypercalcemia ORPHA:94080
Glycogen Storage Disease Due To Lactate Dehydrogenase M-Subunit Deficiency
Elevated creatine kinase after exercise, Hypercalcemia ORPHA:284426
Igg4-Related Thyroid Disease
Hypocalcemia ORPHA:64744
Thymic Neuroendocrine Tumor
Osteopenia, Hypercalcemia ORPHA:97289
Hypocalciuric Hypercalcemia, Familial, Type Ii
Hypercalcemia, Hypermagnesemia OMIM:145981
Autosomal Dominant Kenny-Caffey Syndrome
Cortical thickening of long bone diaphyses, Hypocalcemic tetany, Hyperphosphatemia, Calvarial ost... ORPHA:93325
Glucose-Galactose Malabsorption
Hypercalcemia, Hypernatremia ORPHA:35710
Late-Onset Isolated Acth Deficiency
Generalized bone demineralization, Hyponatremia, Hyperuricemia, Hypercalcemia, Lethargy ORPHA:199299
Osteopetrosis With Renal Tubular Acidosis
Osteopetrosis, Elevated circulating creatine kinase concentration, Hypocalcemia ORPHA:2785
Cranioectodermal Dysplasia 1
Sagittal craniosynostosis, Hypocalcemia, Osteoporosis OMIM:218330
Paternal Uniparental Disomy Of Chromosome 1
Increased blood urea nitrogen, Hypercalcemia, Craniosynostosis ORPHA:251004
Hypoparathyroidism-Sensorineural Deafness-Renal Disease Syndrome
Hypocalcemia, Hypocalcemic seizures ORPHA:2237
Craniofacioskeletal Syndrome
Hypocalcemia OMIM:300712
X-Linked Intellectual Disability-Craniofacioskeletal Syndrome
Hypocalcemia, Hyperbilirubinemia ORPHA:163979
Velocardiofacial Syndrome
Hypocalcemia OMIM:192430
Gitelman Syndrome
Hypocalcemia, Hypomagnesemia, Hypokalemia, Hypermagnesemia ORPHA:358
Infection-Related Hemolytic Uremic Syndrome
Hypocalcemia, Hyperkalemia, Hyponatremia ORPHA:544482
Pheochromocytoma--Islet Cell Tumor Syndrome
Hypercalcemia OMIM:171420
Hennekam Syndrome
Hypocalcemia, Craniosynostosis ORPHA:2136
22Q11.2 Deletion Syndrome
Multiple suture craniosynostosis, Hypocalcemia ORPHA:567
Hyperparathyroidism, Neonatal Severe
Calcinosis, Hypophosphatemia, Hypercalcemia OMIM:239200
Hypophosphatemic Rickets
Hypophosphatemia, Fibrous dysplasia of the bones, Osteomalacia, Patchy variation in bone mineral ... ORPHA:437
Osteoporosis, Hypercalcemia ORPHA:98292
Micrognathia-Recurrent Infections-Behavioral Abnormalities-Mild Intellectual Disability Syndrome
Gait ataxia, Hypercalcemia ORPHA:476126
Acrodysostosis With Multiple Hormone Resistance
Hypocalcemia, Hyperphosphatemia ORPHA:280651
Liver Disease, Severe Congenital
Increased circulating ferritin concentration, Hypocalcemia, Hyperbilirubinemia, Hypoproteinemia, ... OMIM:619991
Bartter Syndrome, Type 1, Antenatal
Hypomagnesemia, Hypokalemia, Osteopenia, Increased circulating renin level, Hypercalcemia, Increa... OMIM:601678
Multiple Myeloma
Osteopenia, Elevated circulating creatinine concentration, Hypercalcemia, Hyperproteinemia ORPHA:29073
Intellectual Disability-Seizures-Hypophosphatasia-Ophthalmic-Skeletal Anomalies Syndrome
Hypertriglyceridemia, Osteopenia, Hypercalcemia, Craniosynostosis ORPHA:369837
Sporadic Pheochromocytoma/Secreting Paraganglioma
Hypercalcemia ORPHA:276621
Acute Adrenal Insufficiency
Increased circulating renin level, Hyponatremia, Hyperuricemia, Hypercalcemia, Hyperkalemia ORPHA:95409
Neurodevelopmental Disorder With Hypotonia And Dysmorphic Facies
Broad-based gait, Hypomagnesemia, Hypocalcemia, Tip-toe gait, Falls OMIM:619503
Hyperparathyroidism-Jaw Tumor Syndrome
Infantile hypercalcemia, Hypophosphatemia, Osteoporosis, Hypercalcemia ORPHA:99880
Parathyroid Carcinoma
Infantile hypercalcemia, Hypophosphatemia, Osteoporosis, Hypercalcemia ORPHA:143
Addison Disease
Increased circulating renin level, Generalized bone demineralization, Hyponatremia, Hyperuricemia... ORPHA:85138
Monosomy 13Q34
Infantile hypercalcemia ORPHA:96168
Osteopetrosis, Autosomal Recessive 7
Osteopetrosis, Hypocalcemic seizures, Abnormal trabecular bone morphology OMIM:612301
Thymic Aplasia
Hypocalcemic tetany ORPHA:83471
Hypercalcemia OMIM:171300
Hereditary Pheochromocytoma-Paraganglioma
Hypercalcemia ORPHA:29072
Hepatocellular Carcinoma
Hypokalemia, Hyperbilirubinemia, Hypoalbuminemia, Hypercalcemia, Hyponatremia ORPHA:88673
Digeorge Syndrome
Hypocalcemia OMIM:188400
Charge Syndrome
Hypocalcemia OMIM:214800
Multiple Endocrine Neoplasia, Type I
Hypercalcemia OMIM:131100
Hypokalemia, Hypercalcemia ORPHA:97282
Multiple Endocrine Neoplasia Type 1
Osteolysis, Hypercalcemia, Lethargy, Reduced bone mineral density ORPHA:652
Johanson-Blizzard Syndrome
Increased VLDL cholesterol concentration, Hypocalcemia OMIM:243800
Hypercalcemia ORPHA:97278
Williams Syndrome
Gait imbalance, Ataxia, Increased bone mineral density, Dysmetria, Abnormal circulating lipid con... ORPHA:904
Hypercalcemia ORPHA:97283
Zollinger-Ellison Syndrome
Hypercalcemia ORPHA:913
Hypercalcemia ORPHA:97261
Multiple Endocrine Neoplasia Type 2
Hypercalcemia ORPHA:653
Hypercalcemia ORPHA:97280
Multiple Endocrine Neoplasia Type 4
Hypercalcemia ORPHA:276152
Williams-Beuren Syndrome
Gait imbalance, Osteopenia, Osteoporosis, Hypercalcemia OMIM:194050
Bone cyst, Hypercalcemia ORPHA:797
Sotos Syndrome
Hypercalcemia, Craniosynostosis ORPHA:821


Summary table of phenotypes displayed during the Histopathology procedure which are considered significant. Full histopathology data table, including submitted images, can be accessed by clicking any row in this table.

There is no histopathology data for Dpf3

IMPC related publications

The table below lists publications which used either products generated by the IMPC or data produced by the phenotyping efforts of the IMPC. These publications have also been associated to Dpf3.

No publications found that use IMPC mice or data for Dpf3.

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MGI Allele Allele Type Produced
Dpf3tm1e(EUCOMM)Wtsi Targeted, non-conditional allele ES Cells
Dpf3em1(IMPC)J Exon Deletion Mice
Dpf3tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells
Dpf3tm1e(EUCOMM)Hmgu Targeted, non-conditional allele ES Cells
Dpf3tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells

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