Nt5dc2 | 5'-nucleotidase domain containing 2

GeneMGI:1917271Synonyms: 2510015F01Rik

Physiological systems

17 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Homeostasis/metabolism Integument Limbs/digits/tail Behavior/neurological

13 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:8Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

impaired righting response1 supporting datasetNt5dc2em1(IMPC)JhomozygoteLate adult4.44x10-6 
increased blood urea nitrogen level1 supporting datasetNt5dc2em1(IMPC)JhomozygoteEarly adult3.91x10-6 
increased circulating creatinine level1 supporting datasetNt5dc2em1(IMPC)JhomozygoteEarly adult1.39x10-11 
abnormal digit morphology1 supporting datasetNt5dc2em1(IMPC)JhomozygoteLate adult2.49x10-5 
decreased grip strength1 supporting datasetNt5dc2em1(IMPC)JhomozygoteEarly adult4.97x10-5 
limb grasping1 supporting datasetNt5dc2em1(IMPC)JhomozygoteLate adult1.61x10-6 
abnormal coat/ hair morphology1 supporting datasetNt5dc2em1(IMPC)JhomozygoteLate adult1.39x10-5 
abnormal autopod morphology1 supporting datasetNt5dc2em1(IMPC)JhomozygoteLate adult2.49x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
Download data as:  










* Does not have a P-value assigned because it was manually marked as significant.
Download data as:  

lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Nt5dc2em1(IMPC)JExon Deletionmouse
Nt5dc2tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)es cell
Nt5dc2tm1(KOMP)WtsiReporter-tagged deletion allele (with selection cassette)targeting vector
es cell

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