Gene: Tspan18

Name
tetraspanin 18
MGI ID
MGI:1917186
Synonyms
2610042G18Rik
Viability
Homozygous - Viable
Other links
Significant phenotypes (0) All measurements (259) Expression & images (74) Disease models (0) Order (3)
View data by physiological system
Significant
Not Significant
Not tested

Filtered by: all phenotypes

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Allele Center Procedure / Parameter Zygosity Mutants Statistical
Method
P Value Status
Tspan18tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Forelimb digit - size HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tspan18tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Tail - thickness HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tspan18tm1.1(KOMP)Vlcg JAX Clinical Chemistry / Alanine aminotransferase HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.180 Success
Tspan18tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Coat - hair distribution - back HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tspan18tm1.1(KOMP)Vlcg JAX Eye Morphology / Bulging eye HOM 8f:7m Fisher Exact Test framework 1.00 Success
Tspan18tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Forelimb nail - shape HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tspan18tm1.1(KOMP)Vlcg JAX Electrocardiogram (ECG) / RR HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0234 Success
Tspan18tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Skin texture - whole body HOM 8f:7m Fisher Exact Test framework 1.00 Success
Tspan18tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Trunk curl HOM 8f:7m Fisher Exact Test framework 0.0627 Success
Tspan18tm1.1(KOMP)Vlcg JAX Eye Morphology / Iris/Pupil HOM 8f:7m Fisher Exact Test framework 0.138 Success
Tspan18tm1.1(KOMP)Vlcg JAX Plasma Chemistry / Triglycerides HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.352 Success
Tspan18tm1.1(KOMP)Vlcg JAX Hematology / Mean cell hemoglobin concentration HOM 5f:4m Mixed Model framework, generalized least squares, equation withoutWeight 0.349 Success
Tspan18tm1.1(KOMP)Vlcg JAX Hematology / Mean cell hemoglobin concentration HOM 2f:3m Not processed 1.00 FAILED - Not enough mutant or control data
Tspan18tm1.1(KOMP)Vlcg JAX Eye Morphology / Corneal deposits HOM 8f:7m Fisher Exact Test framework 1.00 Success
Tspan18tm1.1(KOMP)Vlcg JAX Open Field / Percentage center time HOM 8f:6m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0855 Success
Tspan18tm1.1(KOMP)Vlcg JAX Hematology / Mean platelet volume HOM 2f:3m Not processed 1.00 FAILED - Not enough mutant or control data
Tspan18tm1.1(KOMP)Vlcg JAX Hematology / Eosinophil differential count HOM 2f:3m Not processed 1.00 FAILED - Not enough mutant or control data
Tspan18tm1.1(KOMP)Vlcg JAX Auditory Brain Stem Response / 6kHz-evoked ABR Threshold HOM 2f:2m 1.00 Success
Tspan18tm1.1(KOMP)Vlcg JAX Auditory Brain Stem Response / 6kHz-evoked ABR Threshold HOM 2f:0m 1.00 Success
Tspan18tm1.1(KOMP)Vlcg JAX Body Composition (DEXA lean/fat) / Body length HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0104 Success
Tspan18tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Vibrissae - presence HOM 8f:7m Fisher Exact Test framework 1.00 Success
Tspan18tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Lower teeth appearance HOM 8f:7m Fisher Exact Test framework 1.00 Success
Tspan18tm1.1(KOMP)Vlcg JAX Eye Morphology / Lens Opacity HOM 8f:7m Fisher Exact Test framework 1.00 Success
Tspan18tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Skin texture - back paws HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tspan18tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Forelimbs - shape HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tspan18tm1.1(KOMP)Vlcg JAX Open Field / Periphery distance travelled HOM 8f:6m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0998 Success
Tspan18tm1.1(KOMP)Vlcg JAX Light-Dark Test / Dark side time spent HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.911 Success
Tspan18tm1.1(KOMP)Vlcg JAX Sleep Wake / Sleep light phase percent HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.315 Success
Tspan18tm1.1(KOMP)Vlcg JAX Eye Morphology / Retina (combined) HOM 8f:7m Not processed Success
Tspan18tm1.1(KOMP)Vlcg JAX Tail Suspension / Latency to immobility HOM 7f:6m Mixed Model framework, linear mixed-effects model, equation withWeight 0.370 Success
Tspan18tm1.1(KOMP)Vlcg JAX Clinical Chemistry / Calcium HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.759 Success
Tspan18tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Contact righting HOM 8f:7m Fisher Exact Test framework 1.00 Success
Tspan18tm1.1(KOMP)Vlcg JAX Hematology / Hematocrit HOM 5f:4m Mixed Model framework, generalized least squares, equation withoutWeight 0.871 Success
Tspan18tm1.1(KOMP)Vlcg JAX Hematology / Hematocrit HOM 2f:3m Not processed 1.00 FAILED - Not enough mutant or control data
Tspan18tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Skin color - ear HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tspan18tm1.1(KOMP)Vlcg JAX Grip Strength / Forelimb and hindlimb grip strength normalised against body weight HOM 4f:5m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0866 Success
Tspan18tm1.1(KOMP)Vlcg JAX Grip Strength / Forelimb and hindlimb grip strength normalised against body weight HOM 4f:2m Not processed 1.00 FAILED - Not enough data points in dependent variable 'IMPC_GRS_011_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Tspan18tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Hindlimb nail - number HOM 8f:7m Fisher Exact Test framework 1.00 Success
Tspan18tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Coat - hair texture / appearance - head HOM 8f:7m Fisher Exact Test framework 1.00 Success
Tspan18tm1.1(KOMP)Vlcg JAX Intraperitoneal glucose tolerance test (IPGTT) / Area under glucose response curve HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.683 Success
Tspan18tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Coat - color - abdomen HOM 8f:7m Fisher Exact Test framework 1.00 Success
Tspan18tm1.1(KOMP)Vlcg JAX Rotarod / Learning slope HOM 8f:5m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.266 Success
Tspan18tm1.1(KOMP)Vlcg JAX Eye Morphology / Pupil Dilation HOM 8f:7m Fisher Exact Test framework 1.00 Success
Tspan18tm1.1(KOMP)Vlcg JAX Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI3 HOM 6f:5m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.000601 Success
Tspan18tm1.1(KOMP)Vlcg JAX Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI3 HOM 0f:2m Not processed 1.00 FAILED - Not enough mutant or control data
Tspan18tm1.1(KOMP)Vlcg JAX Clinical Chemistry / Potassium HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.119 Success
Tspan18tm1.1(KOMP)Vlcg JAX Body Composition (DEXA lean/fat) / Fat mass HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.322 Success
Tspan18tm1.1(KOMP)Vlcg JAX Auditory Brain Stem Response / 30kHz-evoked ABR Threshold HOM 2f:2m 0.243 Success
Tspan18tm1.1(KOMP)Vlcg JAX Auditory Brain Stem Response / 30kHz-evoked ABR Threshold HOM 2f:0m 1.00 Success
Tspan18tm1.1(KOMP)Vlcg JAX Clinical Chemistry / Phosphorus HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.768 Success
Tspan18tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Hindpaw - shape HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tspan18tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Tremor HOM 8f:7m Fisher Exact Test framework 1.00 Success
Tspan18tm1.1(KOMP)Vlcg JAX Viability Primary Screen / Outcome HOM 81f:72m Supplied as data Success
Tspan18tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Genitalia - morphology HOM 8f:7m Fisher Exact Test framework 1.00 Success
Tspan18tm1.1(KOMP)Vlcg JAX Hematology / Large Unstained Cell (LUC) count HOM 2f:3m Not processed 1.00 FAILED - Not enough mutant or control data
Tspan18tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Head morphology HOM 8f:7m Fisher Exact Test framework 0.0486 Success
Tspan18tm1.1(KOMP)Vlcg JAX Hematology / Lymphocyte cell count HOM 2f:3m Not processed 1.00 FAILED - Not enough mutant or control data
Tspan18tm1.1(KOMP)Vlcg JAX Sleep Wake / Light sleep bout lengths mean HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.00321 Success
Tspan18tm1.1(KOMP)Vlcg JAX Electrocardiogram (ECG) / ST HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0603 Success
Tspan18tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Upper teeth appearance HOM 8f:7m Fisher Exact Test framework 1.00 Success
Tspan18tm1.1(KOMP)Vlcg JAX Open Field / Center distance travelled HOM 8f:6m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.215 Success
Tspan18tm1.1(KOMP)Vlcg JAX Auditory Brain Stem Response / 18kHz-evoked ABR Threshold HOM 2f:2m 1.00 Success
Tspan18tm1.1(KOMP)Vlcg JAX Auditory Brain Stem Response / 18kHz-evoked ABR Threshold HOM 2f:0m 1.00 Success
Tspan18tm1.1(KOMP)Vlcg JAX Light-Dark Test / Percent time in dark HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.796 Success
Tspan18tm1.1(KOMP)Vlcg JAX Eye Morphology / Corneal vascularization HOM 8f:7m Fisher Exact Test framework 1.00 Success
Tspan18tm1.1(KOMP)Vlcg JAX Sleep Wake / Activity onset with respect to dark onset median HOM 7f:5m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.977 Success
Tspan18tm1.1(KOMP)Vlcg JAX Eye Morphology / Retinal Blood Vessels Pattern HOM 8f:7m Fisher Exact Test framework 1.00 Success
Tspan18tm1.1(KOMP)Vlcg JAX Clinical Chemistry / Triglycerides HOM 7f:6m Mixed Model framework, linear mixed-effects model, equation withWeight 0.130 Success
Tspan18tm1.1(KOMP)Vlcg JAX Electroconvulsive Threshold Testing / mA threshold inducing clonic seizure HOM 8f:5m Mixed Model framework, linear mixed-effects model, equation withWeight 0.00724 Success
Tspan18tm1.1(KOMP)Vlcg JAX Electroconvulsive Threshold Testing / mA threshold inducing clonic seizure HOM 0f:2m Not processed 1.00 FAILED - Not enough mutant or control data
Tspan18tm1.1(KOMP)Vlcg JAX Sleep Wake / Light sleep bout lengths standard deviation HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0107 Success
Tspan18tm1.1(KOMP)Vlcg JAX Electrocardiogram (ECG) / PQ HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.749 Success
Tspan18tm1.1(KOMP)Vlcg JAX Hematology / Platelet count HOM 5f:4m Mixed Model framework, generalized least squares, equation withoutWeight 0.000590 Success
Tspan18tm1.1(KOMP)Vlcg JAX Hematology / Platelet count HOM 2f:3m Not processed 1.00 FAILED - Not enough mutant or control data
Tspan18tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Activity (body position) HOM 8f:7m Fisher Exact Test framework 1.00 Success
Tspan18tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Hindlimb digit - size HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tspan18tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Skin texture - snout HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tspan18tm1.1(KOMP)Vlcg JAX Clinical Chemistry / Total protein HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0885 Success
Tspan18tm1.1(KOMP)Vlcg JAX Eye Morphology / Pupil Position HOM 8f:7m Fisher Exact Test framework 0.0131 Success
Tspan18tm1.1(KOMP)Vlcg JAX Body Composition (DEXA lean/fat) / Fat/Body weight HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.234 Success
Tspan18tm1.1(KOMP)Vlcg JAX Plasma Chemistry / HDL cholesterol HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.995 Success
Tspan18tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Hindlimbs - position HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tspan18tm1.1(KOMP)Vlcg JAX Eye Morphology / Eyelid closure HOM 8f:7m Fisher Exact Test framework 1.00 Success
Tspan18tm1.1(KOMP)Vlcg JAX Light-Dark Test / Time mobile light side HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.672 Success
Tspan18tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Forelimbs - size HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tspan18tm1.1(KOMP)Vlcg JAX Sleep Wake / Breath rate during sleep standard deviation HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.00655 Success
Tspan18tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Tail - morphology HOM 8f:7m Fisher Exact Test framework 1.00 Success
Tspan18tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Coat - color pattern - abdomen HOM 8f:7m Fisher Exact Test framework 1.00 Success
Tspan18tm1.1(KOMP)Vlcg JAX Eye Morphology / Iris transilumination HOM 8f:7m Fisher Exact Test framework 1.00 Success
Tspan18tm1.1(KOMP)Vlcg JAX Clinical Chemistry / Aspartate aminotransferase HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.128 Success
Tspan18tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Hindlimb nail - length HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tspan18tm1.1(KOMP)Vlcg JAX Hematology / Eosinophil cell count HOM 2f:3m Not processed 1.00 FAILED - Not enough mutant or control data
Tspan18tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Vocalization HOM 8f:7m Fisher Exact Test framework 1.00 Success
Tspan18tm1.1(KOMP)Vlcg JAX Tail Suspension / Time immobile HOM 7f:6m Mixed Model framework, linear mixed-effects model, equation withWeight 0.502 Success
Tspan18tm1.1(KOMP)Vlcg JAX Grip Strength / Forelimb and hindlimb grip strength measurement mean HOM 4f:5m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0232 Success
Tspan18tm1.1(KOMP)Vlcg JAX Grip Strength / Forelimb and hindlimb grip strength measurement mean HOM 4f:2m Not processed 1.00 FAILED - Not enough data points in dependent variable 'IMPC_GRS_009_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Tspan18tm1.1(KOMP)Vlcg JAX Hematology / Hemoglobin HOM 5f:4m Mixed Model framework, generalized least squares, equation withoutWeight 0.560 Success
Tspan18tm1.1(KOMP)Vlcg JAX Hematology / Hemoglobin HOM 2f:3m Not processed 1.00 FAILED - Not enough mutant or control data
Tspan18tm1.1(KOMP)Vlcg JAX Open Field / Whole arena resting time HOM 8f:6m Mixed Model framework, linear mixed-effects model, equation withWeight 0.924 Success
Tspan18tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Teeth presence HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tspan18tm1.1(KOMP)Vlcg JAX Eye Morphology / Vitreous HOM 8f:7m Fisher Exact Test framework 1.00 Success
Tspan18tm1.1(KOMP)Vlcg JAX Eye Morphology / Lens HOM 8f:7m Fisher Exact Test framework 0.00113 Success
Tspan18tm1.1(KOMP)Vlcg JAX Electrocardiogram (ECG) / QTc HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0727 Success
Tspan18tm1.1(KOMP)Vlcg JAX Grip Strength / Forelimb grip strength normalised against body weight HOM 4f:5m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0997 Success
Tspan18tm1.1(KOMP)Vlcg JAX Grip Strength / Forelimb grip strength normalised against body weight HOM 4f:2m Not processed 1.00 FAILED - Not enough data points in dependent variable 'IMPC_GRS_010_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Tspan18tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Head size HOM 8f:7m Fisher Exact Test framework 1.00 Success
Tspan18tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Coat - color pattern - back HOM 8f:7m Fisher Exact Test framework 1.00 Success
Tspan18tm1.1(KOMP)Vlcg JAX Eye Morphology / Optic Disc HOM 8f:7m Fisher Exact Test framework 1.00 Success
Tspan18tm1.1(KOMP)Vlcg JAX Open Field / Center average speed HOM 8f:6m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.110 Success
Tspan18tm1.1(KOMP)Vlcg JAX Eye Morphology / Narrow eye opening HOM 8f:7m Fisher Exact Test framework 1.00 Success
Tspan18tm1.1(KOMP)Vlcg JAX Clinical Chemistry / Sodium HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0263 Success
Tspan18tm1.1(KOMP)Vlcg JAX Sleep Wake / Sleep dark phase percent HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.519 Success
Tspan18tm1.1(KOMP)Vlcg JAX Heart Weight / Heart weight HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.452 Success
Tspan18tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Forepaw - shape HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tspan18tm1.1(KOMP)Vlcg JAX Body Composition (DEXA lean/fat) / Bone Mineral Content (excluding skull) HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.303 Success
Tspan18tm1.1(KOMP)Vlcg JAX Hematology / Neutrophil differential count HOM 2f:3m Not processed 1.00 FAILED - Not enough mutant or control data
Tspan18tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Skin color - snout HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tspan18tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Coat - hair texture / appearance - back HOM 8f:7m Fisher Exact Test framework 1.00 Success
Tspan18tm1.1(KOMP)Vlcg JAX Clinical Chemistry / HDL-cholesterol HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.438 Success
Tspan18tm1.1(KOMP)Vlcg JAX Eye Morphology / Persistence of hyaloid vascular system HOM 8f:7m Fisher Exact Test framework 0.675 Success
Tspan18tm1.1(KOMP)Vlcg JAX Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI2 HOM 6f:5m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0479 Success
Tspan18tm1.1(KOMP)Vlcg JAX Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI2 HOM 0f:2m Not processed 1.00 FAILED - Not enough mutant or control data
Tspan18tm1.1(KOMP)Vlcg JAX Eye Morphology / Pupil Shape HOM 8f:7m Fisher Exact Test framework 0.0937 Success
Tspan18tm1.1(KOMP)Vlcg JAX Light-Dark Test / Latency to first transition into dark HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.834 Success
Tspan18tm1.1(KOMP)Vlcg JAX Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - S HOM 6f:5m Mixed Model framework, linear mixed-effects model, equation withWeight 0.907 Success
Tspan18tm1.1(KOMP)Vlcg JAX Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - S HOM 0f:2m Not processed 1.00 FAILED - Not enough mutant or control data
Tspan18tm1.1(KOMP)Vlcg JAX Electrocardiogram (ECG) / QTc Dispersion HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.205 Success
Tspan18tm1.1(KOMP)Vlcg JAX Open Field / Periphery average speed HOM 8f:6m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.656 Success
Tspan18tm1.1(KOMP)Vlcg JAX Fertility of Homozygous Knock-out Mice / Gross Findings Male HOM f:m Supplied as data Success
Tspan18tm1.1(KOMP)Vlcg JAX Eye Morphology / Eye HOM 8f:7m Fisher Exact Test framework 1.00 Success
Tspan18tm1.1(KOMP)Vlcg JAX Sleep Wake / Dark sleep bout lengths standard deviation HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.00247 Success
Tspan18tm1.1(KOMP)Vlcg JAX Hematology / Lymphocyte differential count HOM 2f:3m Not processed 1.00 FAILED - Not enough mutant or control data
Tspan18tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Mouth morphology HOM 8f:7m Fisher Exact Test framework 1.00 Success
Tspan18tm1.1(KOMP)Vlcg JAX Hematology / Monocyte differential count HOM 2f:3m Not processed 1.00 FAILED - Not enough mutant or control data
Tspan18tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Head bobbing HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tspan18tm1.1(KOMP)Vlcg JAX Light-Dark Test / Percent time in light HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.796 Success
Tspan18tm1.1(KOMP)Vlcg JAX Plasma Chemistry / Total cholesterol HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.992 Success
Tspan18tm1.1(KOMP)Vlcg JAX Body Composition (DEXA lean/fat) / Lean/Body weight HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.920 Success
Tspan18tm1.1(KOMP)Vlcg JAX Electrocardiogram (ECG) / rMSSD HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0621 Success
Tspan18tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Skin texture - ear HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tspan18tm1.1(KOMP)Vlcg JAX Open Field / Distance travelled - total HOM 8f:6m Mixed Model framework, linear mixed-effects model, equation withWeight 0.387 Success
Tspan18tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Snout size HOM 8f:7m Fisher Exact Test framework 1.00 Success
Tspan18tm1.1(KOMP)Vlcg JAX Sleep Wake / Dark sleep bout lengths mean HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0140 Success
Tspan18tm1.1(KOMP)Vlcg JAX Electrocardiogram (ECG) / PR HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.578 Success
Tspan18tm1.1(KOMP)Vlcg JAX Eye Morphology / Synechia HOM 8f:7m Fisher Exact Test framework 1.00 Success
Tspan18tm1.1(KOMP)Vlcg JAX Clinical Chemistry / Iron HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.168 Success
Tspan18tm1.1(KOMP)Vlcg JAX Auditory Brain Stem Response / 24kHz-evoked ABR Threshold HOM 2f:2m 0.00919 Success
Tspan18tm1.1(KOMP)Vlcg JAX Auditory Brain Stem Response / 24kHz-evoked ABR Threshold HOM 2f:0m 1.00 Success
Tspan18tm1.1(KOMP)Vlcg JAX Clinical Chemistry / Total cholesterol HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.976 Success
Tspan18tm1.1(KOMP)Vlcg JAX Light-Dark Test / Light side time spent HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.911 Success
Tspan18tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Genitalia - size HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tspan18tm1.1(KOMP)Vlcg JAX Open Field / Periphery permanence time HOM 8f:6m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0854 Success
Tspan18tm1.1(KOMP)Vlcg JAX Clinical Chemistry / Albumin HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0359 Success
Tspan18tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Forelimb nail - length HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tspan18tm1.1(KOMP)Vlcg JAX Electrocardiogram (ECG) / HR HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0165 Success
Tspan18tm1.1(KOMP)Vlcg JAX Intraperitoneal glucose tolerance test (IPGTT) / Initial response to glucose challenge HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.124 Success
Tspan18tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Aggression HOM 8f:7m Fisher Exact Test framework 1.00 Success
Tspan18tm1.1(KOMP)Vlcg JAX Grip Strength / Forelimb grip strength measurement mean HOM 4f:5m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.203 Success
Tspan18tm1.1(KOMP)Vlcg JAX Grip Strength / Forelimb grip strength measurement mean HOM 4f:2m Not processed 1.00 FAILED - Not enough data points in dependent variable 'IMPC_GRS_008_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Tspan18tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Hindlimbs - shape HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tspan18tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Startle response HOM 8f:7m Fisher Exact Test framework 1.00 Success
Tspan18tm1.1(KOMP)Vlcg JAX Eye Morphology / Eyelid morphology HOM 8f:7m Fisher Exact Test framework 1.00 Success
Tspan18tm1.1(KOMP)Vlcg JAX Hematology / Mean cell volume HOM 5f:4m Mixed Model framework, generalized least squares, equation withoutWeight 0.771 Success
Tspan18tm1.1(KOMP)Vlcg JAX Hematology / Mean cell volume HOM 2f:3m Not processed 1.00 FAILED - Not enough mutant or control data
Tspan18tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Coat - color - back HOM 8f:7m Fisher Exact Test framework 1.00 Success
Tspan18tm1.1(KOMP)Vlcg JAX Sleep Wake / Sleep daily percent HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.988 Success
Tspan18tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Forelimb digit - shape HOM 8f:7m Fisher Exact Test framework 1.00 Success
Tspan18tm1.1(KOMP)Vlcg JAX Clinical Chemistry / Free fatty acids HOM 7f:4m Mixed Model framework, linear mixed-effects model, equation withWeight 0.990 Success
Tspan18tm1.1(KOMP)Vlcg JAX Eye Morphology / Cornea HOM 8f:7m Fisher Exact Test framework 1.00 Success
Tspan18tm1.1(KOMP)Vlcg JAX Open Field / Center permanence time HOM 8f:6m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0855 Success
Tspan18tm1.1(KOMP)Vlcg JAX Auditory Brain Stem Response / 12kHz-evoked ABR Threshold HOM 2f:2m 1.00 Success
Tspan18tm1.1(KOMP)Vlcg JAX Auditory Brain Stem Response / 12kHz-evoked ABR Threshold HOM 2f:0m 1.00 Success
Tspan18tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Hindpaw - size HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tspan18tm1.1(KOMP)Vlcg JAX Hematology / Basophil cell count HOM 2f:3m Not processed 1.00 FAILED - Not enough mutant or control data
Tspan18tm1.1(KOMP)Vlcg JAX Body Composition (DEXA lean/fat) / Bone Mineral Density (excluding skull) HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.845 Success
Tspan18tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Upper lip morphology HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tspan18tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Locomotor activity HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0203 Success
Tspan18tm1.1(KOMP)Vlcg JAX Hematology / Red blood cell count HOM 5f:4m Mixed Model framework, generalized least squares, equation withoutWeight 0.988 Success
Tspan18tm1.1(KOMP)Vlcg JAX Hematology / Red blood cell count HOM 2f:3m Not processed 1.00 FAILED - Not enough mutant or control data
Tspan18tm1.1(KOMP)Vlcg JAX Light-Dark Test / Fecal boli HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.890 Success
Tspan18tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Skin texture - tail HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tspan18tm1.1(KOMP)Vlcg JAX Eye Morphology / Iris Pigmentation HOM 8f:7m Fisher Exact Test framework 1.00 Success
Tspan18tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Vibrissae - appearance HOM 8f:7m Fisher Exact Test framework 1.00 Success
Tspan18tm1.1(KOMP)Vlcg JAX Electrocardiogram (ECG) / HRV HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.171 Success
Tspan18tm1.1(KOMP)Vlcg JAX Sleep Wake / Breath rate during sleep mean HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.262 Success
Tspan18tm1.1(KOMP)Vlcg JAX Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI1 HOM 6f:5m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.392 Success
Tspan18tm1.1(KOMP)Vlcg JAX Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI1 HOM 0f:2m Not processed 1.00 FAILED - Not enough mutant or control data
Tspan18tm1.1(KOMP)Vlcg JAX Eye Morphology / Retinal Blood Vessels HOM 8f:7m Fisher Exact Test framework 1.00 Success
Tspan18tm1.1(KOMP)Vlcg JAX Sleep Wake / Sleep bout lengths mean HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0141 Success
Tspan18tm1.1(KOMP)Vlcg JAX Hematology / Neutrophil cell count HOM 2f:3m Not processed 1.00 FAILED - Not enough mutant or control data
Tspan18tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Skin color - back paws HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tspan18tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Limb grasp HOM 8f:7m Fisher Exact Test framework 0.165 Success
Tspan18tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Skin color - whole body HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tspan18tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Coat - hair distribution - abdomen HOM 8f:7m Fisher Exact Test framework 1.00 Success
Tspan18tm1.1(KOMP)Vlcg JAX Rotarod / Average duration HOM 8f:5m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0641 Success
Tspan18tm1.1(KOMP)Vlcg JAX Plasma Chemistry / Glucose HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.000255 Success
Tspan18tm1.1(KOMP)Vlcg JAX Clinical Chemistry / Urea (Blood Urea Nitrogen - BUN) HOM 7f:5m Mixed Model framework, linear mixed-effects model, equation withWeight 0.286 Success
Tspan18tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Coat - color pattern - head HOM 8f:7m Fisher Exact Test framework 1.00 Success
Tspan18tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Genitalia - presence HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tspan18tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Coat - hair distribution - head HOM 8f:7m Fisher Exact Test framework 1.00 Success
Tspan18tm1.1(KOMP)Vlcg JAX Light-Dark Test / Side changes HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.234 Success
Tspan18tm1.1(KOMP)Vlcg JAX Eye Morphology / Corneal Sclerization HOM 8f:7m Fisher Exact Test framework 1.00 Success
Tspan18tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Hindlimb digit - number HOM 8f:7m Fisher Exact Test framework 1.00 Success
Tspan18tm1.1(KOMP)Vlcg JAX Clinical Chemistry / Alkaline phosphatase HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.866 Success
Tspan18tm1.1(KOMP)Vlcg JAX Hole-board Exploration / Total holepokes HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.00934 Success
Tspan18tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Tail - length HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tspan18tm1.1(KOMP)Vlcg JAX Eye Morphology / Eye Hemorrhage or Blood Presence HOM 8f:7m Fisher Exact Test framework 1.00 Success
Tspan18tm1.1(KOMP)Vlcg JAX Hematology / Monocyte cell count HOM 2f:3m Not processed 1.00 FAILED - Not enough mutant or control data
Tspan18tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Hindlimb nail - shape HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tspan18tm1.1(KOMP)Vlcg JAX Open Field / Number of rears - total HOM 8f:6m Mixed Model framework, linear mixed-effects model, equation withWeight 0.000324 Success
Tspan18tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Unexpected behaviors HOM 8f:7m Fisher Exact Test framework 1.00 Success
Tspan18tm1.1(KOMP)Vlcg JAX Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - Global HOM 0f:2m Not processed 1.00 FAILED - Not enough mutant or control data
Tspan18tm1.1(KOMP)Vlcg JAX Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - Global HOM 2f:3m Not processed 1.00 FAILED - Not enough mutant measurements (2f/3m)
Tspan18tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Hindlimbs - size HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tspan18tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Skin texture - front paws HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tspan18tm1.1(KOMP)Vlcg JAX Body Composition (DEXA lean/fat) / Bone Area HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.117 Success
Tspan18tm1.1(KOMP)Vlcg JAX Eye Morphology / Fusion between cornea and lens HOM 8f:7m Fisher Exact Test framework 1.00 Success
Tspan18tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Coat - color - head HOM 8f:7m Fisher Exact Test framework 1.00 Success
Tspan18tm1.1(KOMP)Vlcg JAX Hematology / Mean corpuscular hemoglobin HOM 5f:4m Mixed Model framework, generalized least squares, equation withoutWeight 0.000122 Success
Tspan18tm1.1(KOMP)Vlcg JAX Hematology / Mean corpuscular hemoglobin HOM 2f:3m Not processed 1.00 FAILED - Not enough mutant or control data
Tspan18tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Hindlimb digit - shape HOM 8f:7m Fisher Exact Test framework 0.0438 Success
Tspan18tm1.1(KOMP)Vlcg JAX Intraperitoneal glucose tolerance test (IPGTT) / Fasted blood glucose concentration HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.000360 Success
Tspan18tm1.1(KOMP)Vlcg JAX Hematology / Large Unstained Cell (LUC) differential count HOM 2f:3m Not processed 1.00 FAILED - Not enough mutant or control data
Tspan18tm1.1(KOMP)Vlcg JAX Clinical Chemistry / Total bilirubin HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.254 Success
Tspan18tm1.1(KOMP)Vlcg JAX Electrocardiogram (ECG) / CV HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.150 Success
Tspan18tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Forelimbs - position HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tspan18tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Forepaw - size HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tspan18tm1.1(KOMP)Vlcg JAX Body Composition (DEXA lean/fat) / BMC/Body weight HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.729 Success
Tspan18tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Lower lip morphology HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tspan18tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Skin color - front paws HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tspan18tm1.1(KOMP)Vlcg JAX Hematology / Basophil differential count HOM 2f:3m Not processed 1.00 FAILED - Not enough mutant or control data
Tspan18tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Coat - hair texture / appearance - abdomen HOM 8f:7m Fisher Exact Test framework 1.00 Success
Tspan18tm1.1(KOMP)Vlcg JAX Sleep Wake / Peak wake with respect to dark onset median HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.591 Success
Tspan18tm1.1(KOMP)Vlcg JAX Clinical Chemistry / Glucose HOM 6f:4m Mixed Model framework, linear mixed-effects model, equation withWeight 0.548 Success
Tspan18tm1.1(KOMP)Vlcg JAX Light-Dark Test / Time mobile dark side HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.735 Success
Tspan18tm1.1(KOMP)Vlcg JAX Eye Morphology / Retinal Blood Vessels Structure HOM 8f:7m Fisher Exact Test framework 0.0318 Success
Tspan18tm1.1(KOMP)Vlcg JAX Fertility of Homozygous Knock-out Mice / Gross Findings Female HOM f:m Supplied as data Success
Tspan18tm1.1(KOMP)Vlcg JAX Tail Suspension / Climbing HOM 7f:6m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tspan18tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Forelimb nail - number HOM 8f:7m Fisher Exact Test framework 1.00 Success
Tspan18tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Gait HOM 8f:7m Fisher Exact Test framework 1.00 Success
Tspan18tm1.1(KOMP)Vlcg JAX Electrocardiogram (ECG) / QRS HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.626 Success
Tspan18tm1.1(KOMP)Vlcg JAX Hematology / Red blood cell distribution width HOM 2f:3m Not processed 1.00 FAILED - Not enough mutant or control data
Tspan18tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Ears HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tspan18tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Tail - presence HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tspan18tm1.1(KOMP)Vlcg JAX Clinical Chemistry / Chloride HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.229 Success
Tspan18tm1.1(KOMP)Vlcg JAX Insulin Blood Level / Insulin HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.287 Success
Tspan18tm1.1(KOMP)Vlcg JAX Plasma Chemistry / Free fatty acids HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.241 Success
Tspan18tm1.1(KOMP)Vlcg JAX Rotarod / Learning difference HOM 8f:5m Mixed Model framework, generalized least squares, equation withoutWeight 0.300 Success
Tspan18tm1.1(KOMP)Vlcg JAX Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI4 HOM 0f:2m Not processed 1.00 FAILED - Not enough mutant or control data
Tspan18tm1.1(KOMP)Vlcg JAX Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI4 HOM 2f:3m Not processed 1.00 FAILED - Not enough mutant measurements (2f/3m)
Tspan18tm1.1(KOMP)Vlcg JAX Body Composition (DEXA lean/fat) / Lean mass HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.215 Success
Tspan18tm1.1(KOMP)Vlcg JAX Eye Morphology / Pupil Light Response HOM 8f:7m Fisher Exact Test framework 1.00 Success
Tspan18tm1.1(KOMP)Vlcg JAX Open Field / Whole arena average speed HOM 8f:6m Mixed Model framework, linear mixed-effects model, equation withWeight 0.387 Success
Tspan18tm1.1(KOMP)Vlcg JAX Eye Morphology / Corneal opacity HOM 8f:7m Fisher Exact Test framework 1.00 Success
Tspan18tm1.1(KOMP)Vlcg JAX Sleep Wake / Sleep bout lengths standard deviation HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.00577 Success
Tspan18tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Forelimb digit - number HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tspan18tm1.1(KOMP)Vlcg JAX Hematology / White blood cell count HOM 5f:4m Mixed Model framework, generalized least squares, equation withoutWeight 0.360 Success
Tspan18tm1.1(KOMP)Vlcg JAX Hematology / White blood cell count HOM 2f:3m Not processed 1.00 FAILED - Not enough mutant or control data
Tspan18tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Skin color - tail HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584)  (2/2) N/A
Aorta 2 No  (2/2) N/A
Bone marrow 2 No  (2/2) N/A
Brain 2 No  (2/2) N/A
Brainstem 2 No  (2/2) N/A
Brown adipose tissue 2 No  (2/2) N/A
Cartilage tissue 2 No  (2/2) N/A
Cerebellum 2 No N/A
Cerebral cortex 2 No  (1/2) N/A
Epididymis 2 No  (18/134)  (1/2) N/A
Esophagus 2 No  (7/415)  (2/2) N/A
Eye 2 No  (2/2) N/A
Heart 2 No  (2/2) N/A
Hippocampus 2 No  (2/2) N/A
Hypothalamus 2 No  (2/2) N/A
Kidney 2 No  (18/584)  (2/2) N/A
Large intestine 2 No  (10/584)  (2/2) N/A
Liver 2 No  (2/2) N/A
Lower urinary tract 2 No N/A
Lung 2 No  (2/2) N/A
Lymph node 2 No  (2/2) N/A
Mammary gland 2 No  (1/2) N/A
Midbrain 2 No  (2/2) N/A
Olfactory lobe 2 No  (1/2) N/A
Ovary 2 No  (1/584)  (1/2) N/A
Oviduct 2 No  (1/2) N/A
Pancreas 2 No  (5/584)  (2/2) N/A
Peripheral nervous system 2 No  (2/2) N/A
Peyer's patch 2 No  (2/2) N/A
Pituitary gland 2 No  (1/2) N/A
Prostate gland 2 No  (12/584) N/A
Skeletal muscle 2 No N/A
Skin 2 No  (2/2) N/A
Small intestine 2 No  (9/584)  (2/2) N/A
Spinal cord 2 No  (2/2) N/A
Spleen 2 No  (2/584)  (2/2) N/A
Stomach 2 No  (12/584)  (2/2) N/A
Striatum 2 No  (2/2) N/A
Submandibular gland 2 No  (2/132)  (1/2) N/A
Testis 2 No  (2/584)  (1/2) N/A
Thalamus 2 No  (2/2) N/A
Thymus 2 No  (2/2) N/A
Thyroid gland 2 No  (15/584) N/A
Trachea 2 No  (2/2) N/A
Urinary bladder 2 No N/A
Uterus 2 No  (1/2) N/A
Vascular system 2 No N/A
Vesicular gland 2 No N/A
White adipose tissue 2 No  (2/2) N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2  (6/485)  (2/3) N/A
Dorsal root ganglion 1  (1/47)  (1/1) N/A
Ear 2  (1/485)  (1/3) N/A
Embryo 2  (1/485)  (2/3)  Wholemount images
Eye 2  (1/485)  (2/3) N/A
Foot 2  (1/485)  (1/3) N/A
Forebrain 2  (1/485)  (2/3) N/A
Forelimb 2  (1/485)  (2/3) N/A
Fronto-nasal process 1  (1/48) Image Only N/A
Hand 2  (1/485)  (1/3) N/A
Head 2  (5/485)  (2/3) N/A
Heart 2  (1/485)  (2/3) N/A
Hindbrain 2  (6/485)  (2/3) N/A
Hindlimb 2  (1/485)  (2/3) N/A
Liver 2  (1/485) Image Only N/A
Lung 2  (1/485) Image Only N/A
Mandibular process 2  (1/485)  (2/3) N/A
Maxillary process 2  (1/485)  (2/3) N/A
Midbrain 2  (1/485)  (2/3) N/A
Nose 1  (1/51)  (1/1) N/A
Oral cavity 2  (1/485)  (1/3) N/A
Skin 2  (1/485)  (2/3) N/A
Spinal cord 1  (1/50)  (1/1) N/A
Tail 2  (1/485)  (2/3) N/A
Tail somite 2  (1/485)  (2/3) N/A

 Associated Images

X-ray: XRay Images Forepaw
9 Images
X-ray: XRay Images Dorso Ventral
9 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
9 Images
Combined SHIRPA and Dysmorphology
5 Images
X-ray: XRay Images Skull Lateral Orientation
9 Images
Sleep Wake: Wake state (bmp file)
12 Images
Embryo LacZ: LacZ images wholemount
8 Images
X-ray: XRay Images Lateral Orientation
9 Images

 Disease Models

No associations by disease annotation and gene orthology found.
Please visit the desktop version to see this section

 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Tspan18tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Mice, Targeting vectors, ES Cells
Tspan18tm1.1(KOMP)Vlcg Reporter-tagged deletion allele (post Cre, with no selection cassette) Mice
Tspan18tm95245(L1L2_Bact_P) Targeting vectors

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