Not currently registered for phenotyping at IMPC

Phenotyping is currently not planned for a knockout strain of this gene.

Gene Summary

Name:
solute carrier family 25, member 32
Synonyms:
2610043O12Rik,  Mftc

IMPC Data Collections

  • No Body Weight Data
  • No Embryo Imaging Data
  • No Viability Data

IMPC Phenotype Summary

Significant
Not Significant
Not tested

Phenotypes

The IMPC applies a panel of phenotyping screens to characterise single-gene knockout mice by comparison to wild types. Click on the different tabs to visualise significant phenotypes identified by the IMPC, as well as all data that was measured.

lacZ Expression

Expression data not available

Associated Images

Images submitted by IMPC centres for a selection of procedures. Each set of images is available to view in our image comparator.

Phenotype associated images not available

Human diseases caused by Slc25a32 mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.

The table below shows human diseases associated to Slc25a32 by orthology or direct annotation.

Disease Similarity of
phenotypes
Matching phenotypes Source
Exercise Intolerance, Riboflavin-Responsive
OMIM:616839

The table below shows human diseases predicted to be associated to Slc25a32 by phenotypic similarity.

Disease Similarity of
phenotypes
Matching phenotypes Source
Neural Tube Defects, Folate-Sensitive
Spinal dysraphism OMIM:601634
Spina Bifida-Hypospadias Syndrome
Spina bifida, Spinal dysraphism ORPHA:3176
Neural Tube Defects, X-Linked
Spina bifida, Anencephaly OMIM:301410
Anencephaly 1
Spina bifida, Anencephaly OMIM:206500
Ophthalmoplegia, External, And Myopia
Spina bifida OMIM:311000
Fryns Microphthalmia Syndrome
Neural tube defect OMIM:600776
Acalvaria
Holoprosencephaly, Spina bifida, Hydrocephalus ORPHA:945
Frontal Encephalocele
Spina bifida, Hydrocephalus ORPHA:1931
Dysraphism-Cleft Lip/Palate-Limb Reduction Defects Syndrome
Spina bifida, Anencephaly ORPHA:2476
Aplasia Cutis Congenita
Spinal dysraphism ORPHA:1114
Hemihyperplasia, Isolated
Myelomeningocele OMIM:235000
Neural Tube Defects, Susceptibility To
Myelomeningocele, Hydrocephalus, Anencephaly, Spina bifida occulta OMIM:182940
Camptodactyly With Muscular Hypoplasia, Skeletal Dysplasia, And Abnormal Palmar Creases
Spina bifida OMIM:211960
Nevus Comedonicus Syndrome
Spina bifida, Spina bifida occulta ORPHA:64754
Craniorachischisis
Cervical spina bifida, Sirenomelia, Spinal dysraphism, Anencephaly, Myelomeningocele ORPHA:63260
Blepharocheilodontic Syndrome 1
Neural tube defect OMIM:119580
Acropectorovertebral Dysplasia
Spina bifida ORPHA:957
Caudal Duplication
Spina bifida, Myelomeningocele ORPHA:1756
Split-Hand With Obstructive Uropathy, Spina Bifida, And Diaphragmatic Defects
Myelomeningocele, Hydrocephalus, Spina bifida occulta OMIM:183802
Schisis Association
Spina bifida, Anencephaly ORPHA:63862
Chiari Malformation Type Ii
Spina bifida, Myelomeningocele, Hydrocephalus OMIM:207950
Sirenomelia
Spina bifida, Sirenomelia ORPHA:3169
Wildervanck Syndrome
Meningocele ORPHA:3456
Male Pseudohermaphroditism/Mental Retardation Syndrome, Verloes Type
Cervical spina bifida OMIM:600122
Isolated Klippel-Feil Syndrome
Spina bifida ORPHA:2345
Anophthalmia Plus Syndrome
Spina bifida ORPHA:1104
Posterior Meningocele
Neural tube defect, Meningocele, Occipital meningocele, Lipomyelomeningocele, Hydrocephalus ORPHA:268810
Amish Lethal Microcephaly
Spina bifida ORPHA:99742
Hypertelorism-Hypospadias-Polysyndactyly Syndrome
Exencephaly ORPHA:2211
Aminopterin/Methotrexate Embryofetopathy
Holoprosencephaly, Spinal dysraphism, Anencephaly, Meningocele, Hydrocephalus ORPHA:1908
Camptodactyly Syndrome, Guadalajara Type 1
Spina bifida ORPHA:1327
Czeizel-Losonci Syndrome
Spina bifida, Myelomeningocele, Hydrocephalus, Spina bifida occulta ORPHA:2437
Congenital Lipomatous Overgrowth, Vascular Malformations, And Epidermal Nevi
Spinal dysraphism OMIM:612918
Meckel Syndrome, Type 2
Meningocele, Anencephaly OMIM:603194
Waardenburg Syndrome Type 1
Meningocele, Spina bifida ORPHA:894
Fountain Syndrome
Spina bifida, Spina bifida occulta ORPHA:3219
Diabetic Embryopathy
Spinal dysraphism, Hydrocephalus ORPHA:1926
Iniencephaly
Spina bifida, Holoprosencephaly, Spinal dysraphism, Anencephaly, Myelomeningocele, Hydrocephalus ORPHA:63259
Cerebrocostomandibular Syndrome
Meningocele, Spina bifida, Hydranencephaly, Myelomeningocele ORPHA:1393
Lung Agenesis-Heart Defect-Thumb Anomalies Syndrome
Spina bifida ORPHA:1120
Lumbar Syndrome
Spina bifida, Myelomeningocele ORPHA:83628
Vertebral, Cardiac, Renal, And Limb Defects Syndrome 1
Spinal dysraphism OMIM:617660
Pelvis-Shoulder Dysplasia
Spina bifida, Hydranencephaly, Hydrocephalus ORPHA:2839
Spondyloepimetaphyseal Dysplasia With Joint Laxity, Type 2
Spinal dysraphism OMIM:603546
Vacterl With Hydrocephalus
Arrhinencephaly, Spina bifida, Hydrocephalus, Aqueductal stenosis ORPHA:3412
Waardenburg Syndrome, Type 1
Spina bifida, Myelomeningocele OMIM:193500
Cloacal Exstrophy
Spina bifida, Myelomeningocele ORPHA:93929
Trisomy 20P
Spina bifida, Umbilical hernia ORPHA:261318
Fibular Hemimelia
Spina bifida ORPHA:93323
Hallermann-Streiff Syndrome
Spina bifida OMIM:234100
Nail-Patella Syndrome
Spina bifida OMIM:161200
Mosaic Trisomy 9
Spina bifida ORPHA:99776
Trisomy 18
Holoprosencephaly, Spina bifida, Anencephaly ORPHA:3380
Pagod Syndrome
Meningocele, Spina bifida ORPHA:991
Neurofibromatosis, Type I
Spina bifida, Hydrocephalus, Aqueductal stenosis OMIM:162200
Basal Cell Nevus Syndrome
Spina bifida, Hydrocephalus OMIM:109400
Neu-Laxova Syndrome
Spina bifida ORPHA:2671
Limb Body Wall Complex
Spina bifida, Short umbilical cord, Anencephaly, Spina bifida occulta, Myelomeningocele, Hydrocep... ORPHA:2369
Focal Dermal Hypoplasia
Spina bifida, Umbilical hernia ORPHA:2092
Thrombocytopenia-Absent Radius Syndrome
Spina bifida OMIM:274000
Neu-Laxova Syndrome 1
Spina bifida, Short umbilical cord, Stillbirth, Hydranencephaly, Small placenta OMIM:256520
Aicardi Syndrome
Spina bifida OMIM:304050
Alobar Holoprosencephaly
Hydrocephalus, Neural tube defect ORPHA:93925
Midline Interhemispheric Variant Of Holoprosencephaly
Hydrocephalus, Neural tube defect ORPHA:93926
Lobar Holoprosencephaly
Hydrocephalus, Neural tube defect ORPHA:93924
Semilobar Holoprosencephaly
Hydrocephalus, Neural tube defect ORPHA:220386
Jacobsen Syndrome
Spina bifida ORPHA:2308
Intellectual Disability-Cardiac Anomalies-Short Stature-Joint Laxity Syndrome
Spina bifida ORPHA:508498
Schinzel-Giedion Syndrome
Umbilical hernia, Neural tube defect ORPHA:798
22Q11.2 Deletion Syndrome
Spina bifida, Arrhinencephaly, Umbilical hernia, Meningocele, Hydrocephalus, Occipital myelomenin... ORPHA:567
Fanconi Anemia
Spina bifida, Hydrocephalus, Umbilical hernia ORPHA:84
Koolen-De Vries Syndrome Due To A Point Mutation
Spina bifida, Hydrocephalus ORPHA:363965
17Q21.31 Microdeletion Syndrome
Spina bifida, Hydrocephalus ORPHA:363958
Exstrophy-Epispadias Complex
Spina bifida, Hydrocephalus ORPHA:322
Split Cord Malformation
Cervical spina bifida, Meningocele, Lipomyelomeningocele, Myelomeningocele, Hydrocephalus ORPHA:573278
Vater/Vacterl Association
Spina bifida, Patent urachus OMIM:192350
Exercise Intolerance, Riboflavin-Responsive
OMIM:616839

Histopathology

Summary table of phenotypes displayed during the Histopathology procedure which are considered significant. Full histopathology data table, including submitted images, can be accessed by clicking any row in this table.

There is no histopathology data for Slc25a32

IMPC related publications

The table below lists publications which used either products generated by the IMPC or data produced by the phenotyping efforts of the IMPC. These publications have also been associated to Slc25a32.

No publications found that use IMPC mice or data for Slc25a32.

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MGI Allele Allele Type Produced
Slc25a32tm270498(L1L2_Bact_P) Targeting vectors

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