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Gene: Slc25a32 MGI:1917156

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Not currently registered for phenotyping at IMPC

Phenotyping is currently not planned for a knockout strain of this gene.

Gene Summary

Name:
solute carrier family 25, member 32
Synonyms:
2610043O12Rik,  Mftc

Order Alleles

IMPC Data Collections

  • No Body Weight Data
  • No Embryo Imaging Data
  • No Viability Data

IMPC Phenotype Summary

Significant
Not Significant
Not tested

View all our phenotype data below

Phenotypes

The IMPC applies a panel of phenotyping screens to characterise single-gene knockout mice by comparison to wild types. Click on the different tabs to visualise significant phenotypes identified by the IMPC, as well as all data that was measured.

lacZ Expression

Expression data not available

Associated Images

Images submitted by IMPC centres for a selection of procedures. Each set of images is available to view in our image comparator.

Phenotype associated images not available

Human diseases caused by Slc25a32 mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.

The table below shows human diseases associated to Slc25a32 by orthology or direct annotation.

Disease Similarity of
phenotypes		 Matching phenotypes Source
Exercise Intolerance, Riboflavin-Responsive
OMIM:616839

The table below shows human diseases predicted to be associated to Slc25a32 by phenotypic similarity.

Disease Similarity of
phenotypes		 Matching phenotypes Source
Muscular Dystrophy-Dystroglycanopathy (Congenital With Brain And Eye Anomalies), Type A, 10
Neural tube defect OMIM:615041
Neural Tube Defects, Folate-Sensitive
Spinal dysraphism OMIM:601634
Spina Bifida-Hypospadias Syndrome
Spina bifida, Spinal dysraphism ORPHA:3176
Myelopathy, Htlv-1-Associated
Myelopathy OMIM:159580
Anencephaly 1
Anencephaly, Spina bifida OMIM:206500
Ossification Of The Posterior Longitudinal Ligament Of Spine
Myelopathy OMIM:602475
Hemihyperplasia, Isolated
Myelomeningocele OMIM:235000
Frontal Encephalocele
Encephalocele, Hydrocephalus, Spina bifida ORPHA:1931
Ophthalmoplegia, External, And Myopia
Spina bifida OMIM:311000
Joubert Syndrome 15
Exencephaly OMIM:614464
Congenital Herpes Simplex Virus Infection
Hydranencephaly ORPHA:293
Acalvaria
Hydrocephalus, Holoprosencephaly, Spina bifida ORPHA:945
Neural Tube Defects, Susceptibility To
Spina bifida occulta, Hydrocephalus, Myelomeningocele, Anencephaly OMIM:182940
Isolated Anencephaly/Exencephaly
Anencephaly ORPHA:1048
Fryns Microphthalmia Syndrome
Neural tube defect OMIM:600776
Dysraphism-Cleft Lip/Palate-Limb Reduction Defects Syndrome
Anencephaly, Spina bifida ORPHA:2476
Isolated Hemihyperplasia
Myelomeningocele ORPHA:2128
Congenital Vertical Talus
Myelomeningocele ORPHA:178382
Camptodactyly With Muscular Hypoplasia, Skeletal Dysplasia, And Abnormal Palmar Creases
Spina bifida OMIM:211960
Subependymal Nodular Heterotopia
Occipital encephalocele, Myelomeningocele, Meningocele, Nasofrontal encephalocele ORPHA:101030
Aplasia Cutis Congenita
Spinal dysraphism ORPHA:1114
Wildervanck Syndrome
Meningocele ORPHA:3456
Schisis Association
Encephalocele, Anencephaly, Spina bifida ORPHA:63862
Craniorachischisis
Cervical spina bifida, Myelomeningocele, Anencephaly, Sirenomelia, Spinal dysraphism ORPHA:63260
Nevus Comedonicus Syndrome
Spina bifida occulta, Spina bifida ORPHA:64754
Humero-Radial Synostosis
Meningocele ORPHA:3265
Caudal Duplication
Myelomeningocele, Spina bifida ORPHA:1756
Thoraco-Abdominal Enteric Duplication
Meningocele ORPHA:1759
Chiari Malformation Type Ii
Cervical myelopathy, Myelomeningocele, Hydrocephalus, Spina bifida OMIM:207950
Diaphanospondylodysostosis
Myelomeningocele ORPHA:66637
Acropectorovertebral Dysplasia
Spina bifida ORPHA:957
Muscle-Eye-Brain Disease
Hydrocephalus, Meningocele, Holoprosencephaly ORPHA:588
Meckel Syndrome, Type 2
Encephalocele, Meningocele, Anencephaly OMIM:603194
Meckel Syndrome, Type 4
Encephalocele, Hydrocephalus, Meningocele, Anencephaly OMIM:611134
Blepharocheilodontic Syndrome 1
Neural tube defect OMIM:119580
Aminopterin/Methotrexate Embryofetopathy
Encephalocele, Hydrocephalus, Meningocele, Anencephaly, Spinal dysraphism, Holoprosencephaly ORPHA:1908
Sirenomelia
Spina bifida, Sirenomelia ORPHA:3169
Isolated Posterior Meningocele
Hydrocephalus, Lipomyelomeningocele, Meningocele, Neural tube defect, Occipital meningocele ORPHA:268810
Enlarged Parietal Foramina
Occipital encephalocele, Myelomeningocele ORPHA:60015
Isolated Klippel-Feil Syndrome
Spina bifida ORPHA:2345
Anophthalmia Plus Syndrome
Spina bifida ORPHA:1104
Cleft Lip/Palate-Deafness-Sacral Lipoma Syndrome
Meningocele ORPHA:2003
Hypertelorism-Hypospadias-Polysyndactyly Syndrome
Encephalocele, Exencephaly ORPHA:2211
Histidinemia
Histidinuria, Hyperhistidinemia OMIM:235800
Sacral Defect With Anterior Meningocele
Myeloschisis, Myelomeningocele, Meningocele, Hydrocephalus, Dermal sinus tract OMIM:600145
Aprosencephaly Syndrome
Aprosencephaly, Anencephaly OMIM:207770
Czeizel-Losonci Syndrome
Myelomeningocele, Spina bifida occulta, Hydrocephalus, Spina bifida ORPHA:2437
Alg3-Cdg
Neural tube defect ORPHA:79321
Tyrosinosis
Hypertyrosinemia OMIM:276800
Camptodactyly Syndrome, Guadalajara Type 1
Spina bifida ORPHA:1327
Neurocutaneous Melanocytosis
Meningocele ORPHA:2481
Waardenburg Syndrome Type 1
Meningocele, Spina bifida ORPHA:894
Triploidy
Hydrocephalus, Meningocele, Holoprosencephaly ORPHA:3376
Iniencephaly
Encephalocele, Spina bifida, Hydrocephalus, Myelomeningocele, Anencephaly, Spinal dysraphism, Hol... ORPHA:63259
Amish Lethal Microcephaly
Spina bifida ORPHA:99742
Hepatic Fibrosis-Renal Cysts-Intellectual Disability Syndrome
Meningocele ORPHA:2031
Fountain Syndrome
Spina bifida occulta, Spina bifida ORPHA:3219
Cerebrocostomandibular Syndrome
Hydranencephaly, Myelomeningocele, Meningocele, Spina bifida ORPHA:1393
Lung Agenesis-Heart Defect-Thumb Anomalies Syndrome
Spina bifida ORPHA:1120
Joubert Syndrome 14
Encephalocele, Hydrocephalus, Meningocele OMIM:614424
Autosomal Recessive Spondylocostal Dysostosis
Umbilical hernia, Meningocele, Spina bifida occulta ORPHA:2311
Lumbar Syndrome
Myelomeningocele, Spina bifida ORPHA:83628
Acromelic Frontonasal Dysplasia
Encephalocele, Meningocele ORPHA:1827
Pelvis-Shoulder Dysplasia
Hydranencephaly, Hydrocephalus, Spina bifida ORPHA:2839
Neu-Laxova Syndrome 2
Spina bifida OMIM:616038
Lateral Meningocele Syndrome
Umbilical hernia, Meningocele ORPHA:2789
Waardenburg Syndrome, Type 1
Myelomeningocele, Spina bifida OMIM:193500
Lateral Meningocele Syndrome
Umbilical hernia, Hydrocephalus, Meningocele OMIM:130720
Phakomatosis Pigmentokeratotica
Spina bifida ORPHA:2874
Cloacal Exstrophy
Myelomeningocele, Spina bifida ORPHA:93929
Chromosome 17P13.1 Deletion Syndrome
Umbilical hernia, Hydrocephalus, Spina bifida OMIM:613776
Vacterl With Hydrocephalus
Aqueductal stenosis, Hydrocephalus, Spina bifida ORPHA:3412
Curry-Jones Syndrome
Occipital meningocele, Lipomyelomeningocele OMIM:601707
Trisomy 20P
Umbilical hernia, Spina bifida ORPHA:261318
Pagod Syndrome
Encephalocele, Meningocele, Spina bifida ORPHA:991
Short-Rib Thoracic Dysplasia 14 With Polydactyly
Occipital meningocele, Hydrocephalus, Anencephaly OMIM:616546
Limb Body Wall Complex
Encephalocele, Spina bifida, Myelomeningocele, Hydrocephalus, Anencephaly, Short umbilical cord, ... ORPHA:2369
Nail-Patella Syndrome
Spina bifida OMIM:161200
Trisomy 18
Anencephaly, Holoprosencephaly, Spina bifida ORPHA:3380
Lathosterolosis
Meningocele ORPHA:46059
Autosomal Dominant Palmoplantar Keratoderma And Congenital Alopecia
Meningocele ORPHA:1010
Joubert Syndrome With Jeune Asphyxiating Thoracic Dystrophy
Occipital encephalocele, Meningocele ORPHA:397715
Mosaic Trisomy 9
Spina bifida ORPHA:99776
Fibular Hemimelia
Spina bifida ORPHA:93323
Neu-Laxova Syndrome
Spina bifida ORPHA:2671
Neurofibromatosis, Type I
Aqueductal stenosis, Hydrocephalus, Spina bifida OMIM:162200
Basal Cell Nevus Syndrome 1
Hydrocephalus, Spina bifida OMIM:109400
Phocomelia, Schinzel Type
Meningocele ORPHA:2879
Focal Dermal Hypoplasia
Umbilical hernia, Spina bifida ORPHA:2092
Hallermann-Streiff Syndrome
Spina bifida OMIM:234100
Split Cord Malformation
Cervical spina bifida, Myelomeningocele, Lipomyelomeningocele, Meningocele, Hydrocephalus ORPHA:573278
Holoprosencephaly 7
Alobar holoprosencephaly, Hydrocephalus, Lobar holoprosencephaly, Holoprosencephaly, Occipital me... OMIM:610828
Orofaciodigital Syndrome Vi
Occipital meningocele OMIM:277170
Neu-Laxova Syndrome 1
Spina bifida, Stillbirth, Neonatal death, Small placenta, Short umbilical cord, Hydranencephaly OMIM:256520
Aicardi Syndrome
Spina bifida OMIM:304050
Intellectual Disability-Cardiac Anomalies-Short Stature-Joint Laxity Syndrome
Spina bifida ORPHA:508498
Neurodevelopmental Disorder With Dysmorphic Facies And Thin Corpus Callosum
Spina bifida OMIM:619480
Jacobsen Syndrome
Spina bifida ORPHA:2308
Knobloch Syndrome 1
Occipital meningocele, Occipital encephalocele, Spina bifida occulta OMIM:267750
22Q11.2 Deletion Syndrome
Spina bifida, Hydrocephalus, Meningocele, Occipital myelomeningocele, Umbilical hernia ORPHA:567
Campomelic Dysplasia
Hydrocephalus, Spina bifida, Spinal dysraphism OMIM:114290
Arima Syndrome
Occipital meningocele OMIM:243910
Thrombocytopenia-Absent Radius Syndrome
Spina bifida OMIM:274000
Koolen-De Vries Syndrome Due To A Point Mutation
Hydrocephalus, Spina bifida ORPHA:363965
17Q21.31 Microdeletion Syndrome
Hydrocephalus, Spina bifida ORPHA:363958
Fanconi Anemia
Umbilical hernia, Hydrocephalus, Spina bifida ORPHA:84
Semilobar Holoprosencephaly
Neural tube defect, Hydrocephalus ORPHA:220386
Alobar Holoprosencephaly
Neural tube defect, Hydrocephalus ORPHA:93925
Midline Interhemispheric Variant Of Holoprosencephaly
Neural tube defect, Hydrocephalus ORPHA:93926
Lobar Holoprosencephaly
Neural tube defect, Hydrocephalus ORPHA:93924
Vater/Vacterl Association
Occipital encephalocele, Spina bifida, Patent urachus OMIM:192350
Marfan Syndrome
Meningocele ORPHA:558
Schinzel-Giedion Syndrome
Umbilical hernia, Neural tube defect ORPHA:798
Rubinstein-Taybi Syndrome 1
Spina bifida occulta, Spina bifida OMIM:180849
Exstrophy-Epispadias Complex
Hydrocephalus, Spina bifida ORPHA:322
Otopalatodigital Syndrome, Type Ii
Umbilical hernia, Hydrocephalus, Stillbirth, Spina bifida OMIM:304120
Ulna And Fibula, Absence Of, With Severe Limb Deficiency
Occipital meningocele OMIM:276820
Exercise Intolerance, Riboflavin-Responsive
OMIM:616839

Histopathology

Summary table of phenotypes displayed during the Histopathology procedure which are considered significant. Full histopathology data table, including submitted images, can be accessed by clicking any row in this table.

There is no histopathology data for Slc25a32

IMPC related publications

The table below lists publications which used either products generated by the IMPC or data produced by the phenotyping efforts of the IMPC. These publications have also been associated to Slc25a32.

No publications found that use IMPC mice or data for Slc25a32.

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MGI Allele Allele Type Produced
Slc25a32tm270498(L1L2_Bact_P) KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors

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