Gene: A1cf

Name
APOBEC1 complementation factor
MGI ID
MGI:1917115
Synonyms
1810073H04Rik apobec-1 complementation factor ACF
Viability
Homozygous - Viable
Other links
View data by physiological system
Significant
Not Significant
Not tested

Filtered by: all phenotypes

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Allele Center Procedure / Parameter Zygosity Mutants Statistical
Method
P Value Status
A1cftm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Forelimb digit - size HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
A1cftm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Tail - thickness HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
A1cftm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Coat - hair distribution - back HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
A1cftm1b(EUCOMM)Hmgu JAX Eye Morphology / Bulging eye HOM 8f:8m Fisher Exact Test framework 1.00 Success
A1cftm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Forelimb nail - shape HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
A1cftm1b(EUCOMM)Hmgu JAX Electrocardiogram (ECG) / RR HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.598 Success
A1cftm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Skin texture - whole body HOM 8f:8m Fisher Exact Test framework 1.00 Success
A1cftm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Trunk curl HOM 8f:8m Fisher Exact Test framework 1.00 Success
A1cftm1b(EUCOMM)Hmgu JAX Eye Morphology / Iris/Pupil HOM 8f:8m Fisher Exact Test framework 1.00 Success
A1cftm1b(EUCOMM)Hmgu JAX Eye Morphology / Corneal deposits HOM 8f:8m Fisher Exact Test framework 1.00 Success
A1cftm1b(EUCOMM)Hmgu JAX Auditory Brain Stem Response / 6kHz-evoked ABR Threshold HOM 0f:3m 0.0933 Success
A1cftm1b(EUCOMM)Hmgu JAX Auditory Brain Stem Response / 6kHz-evoked ABR Threshold HOM 3f:0m 1.00 Success
A1cftm1b(EUCOMM)Hmgu JAX Body Composition (DEXA lean/fat) / Body length HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.620 Success
A1cftm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Vibrissae - presence HOM 8f:8m Fisher Exact Test framework 1.00 Success
A1cftm1b(EUCOMM)Hmgu JAX Gross Pathology and Tissue Collection / Thyroid HOM f:m Supplied as data Success
A1cftm1b(EUCOMM)Hmgu JAX Gross Pathology and Tissue Collection / Thyroid HOM f:m Supplied as data Success
A1cftm1b(EUCOMM)Hmgu JAX Gross Pathology and Tissue Collection / Thyroid HOM f:m Supplied as data Success
A1cftm1b(EUCOMM)Hmgu JAX Gross Pathology and Tissue Collection / Thyroid HOM f:m Supplied as data Success
A1cftm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Lower teeth appearance HOM 8f:8m Fisher Exact Test framework 1.00 Success
A1cftm1b(EUCOMM)Hmgu JAX Eye Morphology / Lens Opacity HOM 8f:8m Fisher Exact Test framework 1.00 Success
A1cftm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Skin texture - back paws HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
A1cftm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Forelimbs - shape HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
A1cftm1b(EUCOMM)Hmgu JAX Light-Dark Test / Dark side time spent HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0483 Success
A1cftm1b(EUCOMM)Hmgu JAX Sleep Wake / Sleep light phase percent HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0164 Success
A1cftm1b(EUCOMM)Hmgu JAX Eye Morphology / Retina (combined) HOM 8f:8m Not processed Success
A1cftm1b(EUCOMM)Hmgu JAX Gross Pathology and Tissue Collection / Spleen HOM f:m Supplied as data Success
A1cftm1b(EUCOMM)Hmgu JAX Gross Pathology and Tissue Collection / Spleen HOM f:m Supplied as data Success
A1cftm1b(EUCOMM)Hmgu JAX Gross Pathology and Tissue Collection / Spleen HOM f:m Supplied as data Success
A1cftm1b(EUCOMM)Hmgu JAX Gross Pathology and Tissue Collection / Spleen HOM f:m Supplied as data Success
A1cftm1b(EUCOMM)Hmgu JAX Tail Suspension / Latency to immobility HOM 7f:5m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.354 Success
A1cftm1b(EUCOMM)Hmgu JAX Tail Suspension / Latency to immobility HOM 1f:3m Not processed 1.00 FAILED - Not enough mutant or control data
A1cftm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Contact righting HOM 8f:8m Fisher Exact Test framework 1.00 Success
A1cftm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Skin color - ear HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
A1cftm1b(EUCOMM)Hmgu JAX Gross Pathology and Tissue Collection / Esophagus HOM f:m Supplied as data Success
A1cftm1b(EUCOMM)Hmgu JAX Gross Pathology and Tissue Collection / Esophagus HOM f:m Supplied as data Success
A1cftm1b(EUCOMM)Hmgu JAX Gross Pathology and Tissue Collection / Esophagus HOM f:m Supplied as data Success
A1cftm1b(EUCOMM)Hmgu JAX Gross Pathology and Tissue Collection / Esophagus HOM f:m Supplied as data Success
A1cftm1b(EUCOMM)Hmgu JAX Grip Strength / Forelimb and hindlimb grip strength normalised against body weight HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.807 Success
A1cftm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Hindlimb nail - number HOM 8f:8m Fisher Exact Test framework 1.00 Success
A1cftm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Coat - hair texture / appearance - head HOM 8f:8m Fisher Exact Test framework 1.00 Success
A1cftm1b(EUCOMM)Hmgu JAX Intraperitoneal glucose tolerance test (IPGTT) / Area under glucose response curve HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.000285 Success
A1cftm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Coat - color - abdomen HOM 8f:8m Fisher Exact Test framework 1.00 Success
A1cftm1b(EUCOMM)Hmgu JAX Rotarod / Learning slope HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.607 Success
A1cftm1b(EUCOMM)Hmgu JAX Eye Morphology / Pupil Dilation HOM 8f:8m Fisher Exact Test framework 1.00 Success
A1cftm1b(EUCOMM)Hmgu JAX Body Composition (DEXA lean/fat) / Fat mass HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.00139 Success
A1cftm1b(EUCOMM)Hmgu JAX Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI3 HOM 5f:0m Mixed Model framework, linear mixed-effects model, equation withWeight 0.922 Success
A1cftm1b(EUCOMM)Hmgu JAX Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI3 HOM 3f:8m Not processed 1.00 FAILED - Not enough data points in dependent variable 'IMPC_ACS_035_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
A1cftm1b(EUCOMM)Hmgu JAX Auditory Brain Stem Response / 30kHz-evoked ABR Threshold HOM 0f:3m 0.138 Success
A1cftm1b(EUCOMM)Hmgu JAX Auditory Brain Stem Response / 30kHz-evoked ABR Threshold HOM 3f:0m 1.00 Success
A1cftm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Hindpaw - shape HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
A1cftm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Tremor HOM 8f:8m Fisher Exact Test framework 1.00 Success
A1cftm1b(EUCOMM)Hmgu JAX Viability Primary Screen / Outcome HOM 22f:35m Supplied as data Success
A1cftm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Genitalia - morphology HOM 8f:8m Fisher Exact Test framework 1.00 Success
A1cftm1b(EUCOMM)Hmgu JAX Gross Pathology and Tissue Collection / Brain HOM f:m Supplied as data Success
A1cftm1b(EUCOMM)Hmgu JAX Gross Pathology and Tissue Collection / Brain HOM f:m Supplied as data Success
A1cftm1b(EUCOMM)Hmgu JAX Gross Pathology and Tissue Collection / Brain HOM f:m Supplied as data Success
A1cftm1b(EUCOMM)Hmgu JAX Gross Pathology and Tissue Collection / Brain HOM f:m Supplied as data Success
A1cftm1b(EUCOMM)Hmgu JAX Gross Pathology and Tissue Collection / Lymph node HOM f:m Supplied as data Success
A1cftm1b(EUCOMM)Hmgu JAX Gross Pathology and Tissue Collection / Lymph node HOM f:m Supplied as data Success
A1cftm1b(EUCOMM)Hmgu JAX Gross Pathology and Tissue Collection / Lymph node HOM f:m Supplied as data Success
A1cftm1b(EUCOMM)Hmgu JAX Gross Pathology and Tissue Collection / Lymph node HOM f:m Supplied as data Success
A1cftm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Head morphology HOM 8f:8m Fisher Exact Test framework 1.00 Success
A1cftm1b(EUCOMM)Hmgu JAX Sleep Wake / Light sleep bout lengths mean HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0841 Success
A1cftm1b(EUCOMM)Hmgu JAX Electrocardiogram (ECG) / ST HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.913 Success
A1cftm1b(EUCOMM)Hmgu JAX Electroretinography 2 / Rod b-wave amplitude HOM 2f:2m Not processed 1.00 FAILED - Not enough mutant or control data
A1cftm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Upper teeth appearance HOM 8f:8m Fisher Exact Test framework 1.00 Success
A1cftm1b(EUCOMM)Hmgu JAX Auditory Brain Stem Response / 18kHz-evoked ABR Threshold HOM 0f:3m 1.00 Success
A1cftm1b(EUCOMM)Hmgu JAX Auditory Brain Stem Response / 18kHz-evoked ABR Threshold HOM 3f:0m 1.00 Success
A1cftm1b(EUCOMM)Hmgu JAX Light-Dark Test / Percent time in dark HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0547 Success
A1cftm1b(EUCOMM)Hmgu JAX Eye Morphology / Corneal vascularization HOM 8f:8m Fisher Exact Test framework 1.00 Success
A1cftm1b(EUCOMM)Hmgu JAX Eye Morphology / Retinal Blood Vessels Pattern HOM 8f:8m Fisher Exact Test framework 1.00 Success
A1cftm1b(EUCOMM)Hmgu JAX Electroconvulsive Threshold Testing / mA threshold inducing clonic seizure HOM 7f:5m Mixed Model framework, linear mixed-effects model, equation withWeight 0.776 Success
A1cftm1b(EUCOMM)Hmgu JAX Electroconvulsive Threshold Testing / mA threshold inducing clonic seizure HOM 1f:3m Not processed 1.00 FAILED - Not enough mutant or control data
A1cftm1b(EUCOMM)Hmgu JAX Sleep Wake / Light sleep bout lengths standard deviation HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0288 Success
A1cftm1b(EUCOMM)Hmgu JAX Electrocardiogram (ECG) / PQ HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.113 Success
A1cftm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Activity (body position) HOM 8f:8m Fisher Exact Test framework 1.00 Success
A1cftm1b(EUCOMM)Hmgu JAX Gross Pathology and Tissue Collection / Liver HOM f:m Supplied as data Success
A1cftm1b(EUCOMM)Hmgu JAX Gross Pathology and Tissue Collection / Liver HOM f:m Supplied as data Success
A1cftm1b(EUCOMM)Hmgu JAX Gross Pathology and Tissue Collection / Liver HOM f:m Supplied as data Success
A1cftm1b(EUCOMM)Hmgu JAX Gross Pathology and Tissue Collection / Liver HOM f:m Supplied as data Success
A1cftm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Hindlimb digit - size HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
A1cftm1b(EUCOMM)Hmgu JAX Gross Pathology and Tissue Collection / Thymus HOM f:m Supplied as data Success
A1cftm1b(EUCOMM)Hmgu JAX Gross Pathology and Tissue Collection / Thymus HOM f:m Supplied as data Success
A1cftm1b(EUCOMM)Hmgu JAX Gross Pathology and Tissue Collection / Thymus HOM f:m Supplied as data Success
A1cftm1b(EUCOMM)Hmgu JAX Gross Pathology and Tissue Collection / Thymus HOM f:m Supplied as data Success
A1cftm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Skin texture - snout HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
A1cftm1b(EUCOMM)Hmgu JAX Eye Morphology / Pupil Position HOM 8f:8m Fisher Exact Test framework 1.00 Success
A1cftm1b(EUCOMM)Hmgu JAX Body Composition (DEXA lean/fat) / Fat/Body weight HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0370 Success
A1cftm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Hindlimbs - position HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
A1cftm1b(EUCOMM)Hmgu JAX Eye Morphology / Eyelid closure HOM 8f:8m Fisher Exact Test framework 1.00 Success
A1cftm1b(EUCOMM)Hmgu JAX Light-Dark Test / Time mobile light side HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.00726 Success
A1cftm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Forelimbs - size HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
A1cftm1b(EUCOMM)Hmgu JAX Sleep Wake / Breath rate during sleep standard deviation HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.543 Success
A1cftm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Tail - morphology HOM 8f:8m Fisher Exact Test framework 1.00 Success
A1cftm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Coat - color pattern - abdomen HOM 8f:8m Fisher Exact Test framework 1.00 Success
A1cftm1b(EUCOMM)Hmgu JAX Eye Morphology / Iris transilumination HOM 8f:8m Fisher Exact Test framework 1.00 Success
A1cftm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Hindlimb nail - length HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
A1cftm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Vocalization HOM 8f:8m Fisher Exact Test framework 1.00 Success
A1cftm1b(EUCOMM)Hmgu JAX Tail Suspension / Time immobile HOM 7f:5m Mixed Model framework, generalized least squares, equation withoutWeight 0.724 Success
A1cftm1b(EUCOMM)Hmgu JAX Tail Suspension / Time immobile HOM 1f:3m Not processed 1.00 FAILED - Not enough mutant or control data
A1cftm1b(EUCOMM)Hmgu JAX Grip Strength / Forelimb and hindlimb grip strength measurement mean HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.881 Success
A1cftm1b(EUCOMM)Hmgu JAX Electroretinography 2 / Rod b-wave amplitude-left HOM 2f:2m Not processed 1.00 FAILED - Not enough mutant or control data
A1cftm1b(EUCOMM)Hmgu JAX Eye Morphology / Vitreous HOM 8f:8m Fisher Exact Test framework 1.00 Success
A1cftm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Teeth presence HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
A1cftm1b(EUCOMM)Hmgu JAX Eye Morphology / Lens HOM 8f:8m Fisher Exact Test framework 0.0339 Success
A1cftm1b(EUCOMM)Hmgu JAX Electrocardiogram (ECG) / QTc HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.881 Success
A1cftm1b(EUCOMM)Hmgu JAX Grip Strength / Forelimb grip strength normalised against body weight HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.00270 Success
A1cftm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Head size HOM 8f:8m Fisher Exact Test framework 1.00 Success
A1cftm1b(EUCOMM)Hmgu JAX Eye Morphology / Optic Disc HOM 8f:8m Fisher Exact Test framework 1.00 Success
A1cftm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Coat - color pattern - back HOM 8f:8m Fisher Exact Test framework 1.00 Success
A1cftm1b(EUCOMM)Hmgu JAX Eye Morphology / Narrow eye opening HOM 8f:8m Fisher Exact Test framework 0.110 Success
A1cftm1b(EUCOMM)Hmgu JAX Sleep Wake / Sleep dark phase percent HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.511 Success
A1cftm1b(EUCOMM)Hmgu JAX Heart Weight / Heart weight HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0452 Success
A1cftm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Forepaw - shape HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
A1cftm1b(EUCOMM)Hmgu JAX Body Composition (DEXA lean/fat) / Bone Mineral Content (excluding skull) HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.111 Success
A1cftm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Skin color - snout HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
A1cftm1b(EUCOMM)Hmgu JAX Gross Pathology and Tissue Collection / Skin HOM f:m Supplied as data Success
A1cftm1b(EUCOMM)Hmgu JAX Gross Pathology and Tissue Collection / Skin HOM f:m Supplied as data Success
A1cftm1b(EUCOMM)Hmgu JAX Gross Pathology and Tissue Collection / Skin HOM f:m Supplied as data Success
A1cftm1b(EUCOMM)Hmgu JAX Gross Pathology and Tissue Collection / Skin HOM f:m Supplied as data Success
A1cftm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Coat - hair texture / appearance - back HOM 8f:8m Fisher Exact Test framework 1.00 Success
A1cftm1b(EUCOMM)Hmgu JAX Gross Pathology and Tissue Collection / Lung HOM f:m Supplied as data Success
A1cftm1b(EUCOMM)Hmgu JAX Gross Pathology and Tissue Collection / Lung HOM f:m Supplied as data Success
A1cftm1b(EUCOMM)Hmgu JAX Gross Pathology and Tissue Collection / Lung HOM f:m Supplied as data Success
A1cftm1b(EUCOMM)Hmgu JAX Gross Pathology and Tissue Collection / Lung HOM f:m Supplied as data Success
A1cftm1b(EUCOMM)Hmgu JAX Eye Morphology / Persistence of hyaloid vascular system HOM 8f:8m Fisher Exact Test framework 0.0381 Success
A1cftm1b(EUCOMM)Hmgu JAX Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI2 HOM 5f:0m Mixed Model framework, linear mixed-effects model, equation withWeight 0.389 Success
A1cftm1b(EUCOMM)Hmgu JAX Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI2 HOM 3f:8m Not processed 1.00 FAILED - Not enough data points in dependent variable 'IMPC_ACS_034_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
A1cftm1b(EUCOMM)Hmgu JAX Eye Morphology / Pupil Shape HOM 8f:8m Fisher Exact Test framework 0.237 Success
A1cftm1b(EUCOMM)Hmgu JAX Light-Dark Test / Latency to first transition into dark HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.668 Success
A1cftm1b(EUCOMM)Hmgu JAX Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - S HOM 5f:0m Mixed Model framework, linear mixed-effects model, equation withWeight 0.980 Success
A1cftm1b(EUCOMM)Hmgu JAX Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - S HOM 3f:8m Not processed 1.00 FAILED - Not enough data points in dependent variable 'IMPC_ACS_006_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
A1cftm1b(EUCOMM)Hmgu JAX Electrocardiogram (ECG) / QTc Dispersion HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.913 Success
A1cftm1b(EUCOMM)Hmgu JAX Fertility of Homozygous Knock-out Mice / Gross Findings Male HOM f:m Supplied as data Success
A1cftm1b(EUCOMM)Hmgu JAX Eye Morphology / Eye HOM 8f:8m Fisher Exact Test framework 1.00 Success
A1cftm1b(EUCOMM)Hmgu JAX Sleep Wake / Dark sleep bout lengths standard deviation HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.181 Success
A1cftm1b(EUCOMM)Hmgu JAX Gross Pathology and Tissue Collection / Pancreas HOM f:m Supplied as data Success
A1cftm1b(EUCOMM)Hmgu JAX Gross Pathology and Tissue Collection / Pancreas HOM f:m Supplied as data Success
A1cftm1b(EUCOMM)Hmgu JAX Gross Pathology and Tissue Collection / Pancreas HOM f:m Supplied as data Success
A1cftm1b(EUCOMM)Hmgu JAX Gross Pathology and Tissue Collection / Pancreas HOM f:m Supplied as data Success
A1cftm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Mouth morphology HOM 8f:8m Fisher Exact Test framework 1.00 Success
A1cftm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Head bobbing HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
A1cftm1b(EUCOMM)Hmgu JAX Light-Dark Test / Percent time in light HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0547 Success
A1cftm1b(EUCOMM)Hmgu JAX Gross Pathology and Tissue Collection / Spinal cord HOM f:m Supplied as data Success
A1cftm1b(EUCOMM)Hmgu JAX Gross Pathology and Tissue Collection / Spinal cord HOM f:m Supplied as data Success
A1cftm1b(EUCOMM)Hmgu JAX Gross Pathology and Tissue Collection / Spinal cord HOM f:m Supplied as data Success
A1cftm1b(EUCOMM)Hmgu JAX Gross Pathology and Tissue Collection / Spinal cord HOM f:m Supplied as data Success
A1cftm1b(EUCOMM)Hmgu JAX Body Composition (DEXA lean/fat) / Lean/Body weight HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.00456 Success
A1cftm1b(EUCOMM)Hmgu JAX Electrocardiogram (ECG) / rMSSD HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0139 Success
A1cftm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Skin texture - ear HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
A1cftm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Snout size HOM 8f:8m Fisher Exact Test framework 1.00 Success
A1cftm1b(EUCOMM)Hmgu JAX Sleep Wake / Dark sleep bout lengths mean HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.00332 Success
A1cftm1b(EUCOMM)Hmgu JAX Electrocardiogram (ECG) / PR HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0603 Success
A1cftm1b(EUCOMM)Hmgu JAX Eye Morphology / Synechia HOM 8f:8m Fisher Exact Test framework 1.00 Success
A1cftm1b(EUCOMM)Hmgu JAX Auditory Brain Stem Response / 24kHz-evoked ABR Threshold HOM 3f:0m 1.00 Success
A1cftm1b(EUCOMM)Hmgu JAX Auditory Brain Stem Response / 24kHz-evoked ABR Threshold HOM 0f:3m 1.00 Success
A1cftm1b(EUCOMM)Hmgu JAX Light-Dark Test / Light side time spent HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0483 Success
A1cftm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Genitalia - size HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
A1cftm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Forelimb nail - length HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
A1cftm1b(EUCOMM)Hmgu JAX Intraperitoneal glucose tolerance test (IPGTT) / Initial response to glucose challenge HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0473 Success
A1cftm1b(EUCOMM)Hmgu JAX Electrocardiogram (ECG) / HR HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.554 Success
A1cftm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Aggression HOM 8f:8m Fisher Exact Test framework 1.00 Success
A1cftm1b(EUCOMM)Hmgu JAX Electroretinography 2 / Rod b-wave amplitude-right HOM 2f:2m Not processed 1.00 FAILED - Not enough mutant or control data
A1cftm1b(EUCOMM)Hmgu JAX Gross Pathology and Tissue Collection / Adrenal gland HOM f:m Supplied as data Success
A1cftm1b(EUCOMM)Hmgu JAX Gross Pathology and Tissue Collection / Adrenal gland HOM f:m Supplied as data Success
A1cftm1b(EUCOMM)Hmgu JAX Gross Pathology and Tissue Collection / Adrenal gland HOM f:m Supplied as data Success
A1cftm1b(EUCOMM)Hmgu JAX Gross Pathology and Tissue Collection / Adrenal gland HOM f:m Supplied as data Success
A1cftm1b(EUCOMM)Hmgu JAX Grip Strength / Forelimb grip strength measurement mean HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.000838 Success
A1cftm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Hindlimbs - shape HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
A1cftm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Startle response HOM 8f:8m Fisher Exact Test framework 1.00 Success
A1cftm1b(EUCOMM)Hmgu JAX Gross Pathology and Tissue Collection / Urinary bladder HOM f:m Supplied as data Success
A1cftm1b(EUCOMM)Hmgu JAX Gross Pathology and Tissue Collection / Urinary bladder HOM f:m Supplied as data Success
A1cftm1b(EUCOMM)Hmgu JAX Gross Pathology and Tissue Collection / Urinary bladder HOM f:m Supplied as data Success
A1cftm1b(EUCOMM)Hmgu JAX Gross Pathology and Tissue Collection / Urinary bladder HOM f:m Supplied as data Success
A1cftm1b(EUCOMM)Hmgu JAX Eye Morphology / Eyelid morphology HOM 8f:8m Fisher Exact Test framework 1.00 Success
A1cftm1b(EUCOMM)Hmgu JAX Gross Pathology and Tissue Collection / Gall bladder HOM f:m Supplied as data Success
A1cftm1b(EUCOMM)Hmgu JAX Gross Pathology and Tissue Collection / Gall bladder HOM f:m Supplied as data Success
A1cftm1b(EUCOMM)Hmgu JAX Gross Pathology and Tissue Collection / Gall bladder HOM f:m Supplied as data Success
A1cftm1b(EUCOMM)Hmgu JAX Gross Pathology and Tissue Collection / Gall bladder HOM f:m Supplied as data Success
A1cftm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Coat - color - back HOM 8f:8m Fisher Exact Test framework 1.00 Success
A1cftm1b(EUCOMM)Hmgu JAX Sleep Wake / Sleep daily percent HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.370 Success
A1cftm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Forelimb digit - shape HOM 8f:8m Fisher Exact Test framework 1.00 Success
A1cftm1b(EUCOMM)Hmgu JAX Eye Morphology / Cornea HOM 8f:8m Fisher Exact Test framework 1.00 Success
A1cftm1b(EUCOMM)Hmgu JAX Auditory Brain Stem Response / 12kHz-evoked ABR Threshold HOM 0f:3m 1.00 Success
A1cftm1b(EUCOMM)Hmgu JAX Auditory Brain Stem Response / 12kHz-evoked ABR Threshold HOM 3f:0m 1.00 Success
A1cftm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Hindpaw - size HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
A1cftm1b(EUCOMM)Hmgu JAX Body Composition (DEXA lean/fat) / Bone Mineral Density (excluding skull) HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0499 Success
A1cftm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Upper lip morphology HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
A1cftm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Locomotor activity HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.471 Success
A1cftm1b(EUCOMM)Hmgu JAX Light-Dark Test / Fecal boli HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.290 Success
A1cftm1b(EUCOMM)Hmgu JAX Gross Pathology and Tissue Collection / Skeletal muscle HOM f:m Supplied as data Success
A1cftm1b(EUCOMM)Hmgu JAX Gross Pathology and Tissue Collection / Skeletal muscle HOM f:m Supplied as data Success
A1cftm1b(EUCOMM)Hmgu JAX Gross Pathology and Tissue Collection / Skeletal muscle HOM f:m Supplied as data Success
A1cftm1b(EUCOMM)Hmgu JAX Gross Pathology and Tissue Collection / Skeletal muscle HOM f:m Supplied as data Success
A1cftm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Skin texture - tail HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
A1cftm1b(EUCOMM)Hmgu JAX Eye Morphology / Iris Pigmentation HOM 8f:8m Fisher Exact Test framework 1.00 Success
A1cftm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Vibrissae - appearance HOM 8f:8m Fisher Exact Test framework 1.00 Success
A1cftm1b(EUCOMM)Hmgu JAX Sleep Wake / Breath rate during sleep mean HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0369 Success
A1cftm1b(EUCOMM)Hmgu JAX Electrocardiogram (ECG) / HRV HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.607 Success
A1cftm1b(EUCOMM)Hmgu JAX Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI1 HOM 5f:0m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.462 Success
A1cftm1b(EUCOMM)Hmgu JAX Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI1 HOM 3f:8m Not processed 1.00 FAILED - Not enough data points in dependent variable 'IMPC_ACS_033_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
A1cftm1b(EUCOMM)Hmgu JAX Eye Morphology / Retinal Blood Vessels HOM 8f:8m Fisher Exact Test framework 1.00 Success
A1cftm1b(EUCOMM)Hmgu JAX Sleep Wake / Sleep bout lengths mean HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0848 Success
A1cftm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Skin color - back paws HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
A1cftm1b(EUCOMM)Hmgu JAX Electroretinography 2 / Rod a-wave amplitude-right HOM 2f:2m Not processed 1.00 FAILED - Not enough mutant or control data
A1cftm1b(EUCOMM)Hmgu JAX Gross Pathology and Tissue Collection / Large intestine HOM f:m Supplied as data Success
A1cftm1b(EUCOMM)Hmgu JAX Gross Pathology and Tissue Collection / Large intestine HOM f:m Supplied as data Success
A1cftm1b(EUCOMM)Hmgu JAX Gross Pathology and Tissue Collection / Large intestine HOM f:m Supplied as data Success
A1cftm1b(EUCOMM)Hmgu JAX Gross Pathology and Tissue Collection / Large intestine HOM f:m Supplied as data Success
A1cftm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Limb grasp HOM 8f:8m Fisher Exact Test framework 1.00 Success
A1cftm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Skin color - whole body HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
A1cftm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Coat - hair distribution - abdomen HOM 8f:8m Fisher Exact Test framework 1.00 Success
A1cftm1b(EUCOMM)Hmgu JAX Rotarod / Average duration HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.615 Success
A1cftm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Coat - color pattern - head HOM 8f:8m Fisher Exact Test framework 1.00 Success
A1cftm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Genitalia - presence HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
A1cftm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Coat - hair distribution - head HOM 8f:8m Fisher Exact Test framework 1.00 Success
A1cftm1b(EUCOMM)Hmgu JAX Light-Dark Test / Side changes HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.582 Success
A1cftm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Hindlimb digit - number HOM 8f:8m Fisher Exact Test framework 1.00 Success
A1cftm1b(EUCOMM)Hmgu JAX Eye Morphology / Corneal Sclerization HOM 8f:8m Fisher Exact Test framework 1.00 Success
A1cftm1b(EUCOMM)Hmgu JAX Gross Pathology and Tissue Collection / Stomach HOM f:m Supplied as data Success
A1cftm1b(EUCOMM)Hmgu JAX Gross Pathology and Tissue Collection / Stomach HOM f:m Supplied as data Success
A1cftm1b(EUCOMM)Hmgu JAX Gross Pathology and Tissue Collection / Stomach HOM f:m Supplied as data Success
A1cftm1b(EUCOMM)Hmgu JAX Gross Pathology and Tissue Collection / Stomach HOM f:m Supplied as data Success
A1cftm1b(EUCOMM)Hmgu JAX Hole-board Exploration / Total holepokes HOM 8f:4m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0196 Success
A1cftm1b(EUCOMM)Hmgu JAX Electroretinography 2 / Cone b-wave amplitude HOM 2f:2m Not processed 1.00 FAILED - Not enough mutant or control data
A1cftm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Tail - length HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
A1cftm1b(EUCOMM)Hmgu JAX Eye Morphology / Eye Hemorrhage or Blood Presence HOM 8f:8m Fisher Exact Test framework 1.00 Success
A1cftm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Hindlimb nail - shape HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
A1cftm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Unexpected behaviors HOM 8f:8m Fisher Exact Test framework 1.00 Success
A1cftm1b(EUCOMM)Hmgu JAX Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - Global HOM 1f:3m Not processed 1.00 FAILED - Not enough mutant measurements (1f/3m)
A1cftm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Hindlimbs - size HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
A1cftm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Skin texture - front paws HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
A1cftm1b(EUCOMM)Hmgu JAX Body Composition (DEXA lean/fat) / Bone Area HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.224 Success
A1cftm1b(EUCOMM)Hmgu JAX Eye Morphology / Fusion between cornea and lens HOM 8f:8m Fisher Exact Test framework 1.00 Success
A1cftm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Coat - color - head HOM 8f:8m Fisher Exact Test framework 1.00 Success
A1cftm1b(EUCOMM)Hmgu JAX Electroretinography 2 / Rod b-wave implicit time HOM 2f:2m Not processed 1.00 FAILED - Not enough mutant or control data
A1cftm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Hindlimb digit - shape HOM 8f:8m Fisher Exact Test framework 1.00 Success
A1cftm1b(EUCOMM)Hmgu JAX Intraperitoneal glucose tolerance test (IPGTT) / Fasted blood glucose concentration HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0105 Success
A1cftm1b(EUCOMM)Hmgu JAX Gross Pathology and Tissue Collection / Heart HOM f:m Supplied as data Success
A1cftm1b(EUCOMM)Hmgu JAX Gross Pathology and Tissue Collection / Heart HOM f:m Supplied as data Success
A1cftm1b(EUCOMM)Hmgu JAX Gross Pathology and Tissue Collection / Heart HOM f:m Supplied as data Success
A1cftm1b(EUCOMM)Hmgu JAX Gross Pathology and Tissue Collection / Heart HOM f:m Supplied as data Success
A1cftm1b(EUCOMM)Hmgu JAX Electrocardiogram (ECG) / CV HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.714 Success
A1cftm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Forelimbs - position HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
A1cftm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Forepaw - size HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
A1cftm1b(EUCOMM)Hmgu JAX Electroretinography 2 / Cone b-wave amplitude-left HOM 2f:2m Not processed 1.00 FAILED - Not enough mutant or control data
A1cftm1b(EUCOMM)Hmgu JAX Body Composition (DEXA lean/fat) / BMC/Body weight HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.00495 Success
A1cftm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Lower lip morphology HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
A1cftm1b(EUCOMM)Hmgu JAX Gross Pathology and Tissue Collection / Trachea HOM f:m Supplied as data Success
A1cftm1b(EUCOMM)Hmgu JAX Gross Pathology and Tissue Collection / Trachea HOM f:m Supplied as data Success
A1cftm1b(EUCOMM)Hmgu JAX Gross Pathology and Tissue Collection / Trachea HOM f:m Supplied as data Success
A1cftm1b(EUCOMM)Hmgu JAX Gross Pathology and Tissue Collection / Trachea HOM f:m Supplied as data Success
A1cftm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Skin color - front paws HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
A1cftm1b(EUCOMM)Hmgu JAX Electroretinography 2 / Cone b-wave amplitude-right HOM 2f:2m Not processed 1.00 FAILED - Not enough mutant or control data
A1cftm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Coat - hair texture / appearance - abdomen HOM 8f:8m Fisher Exact Test framework 1.00 Success
A1cftm1b(EUCOMM)Hmgu JAX Sleep Wake / Peak wake with respect to dark onset median HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.118 Success
A1cftm1b(EUCOMM)Hmgu JAX Light-Dark Test / Time mobile dark side HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.638 Success
A1cftm1b(EUCOMM)Hmgu JAX Eye Morphology / Retinal Blood Vessels Structure HOM 8f:8m Fisher Exact Test framework 1.00 Success
A1cftm1b(EUCOMM)Hmgu JAX Fertility of Homozygous Knock-out Mice / Gross Findings Female HOM f:m Supplied as data Success
A1cftm1b(EUCOMM)Hmgu JAX Tail Suspension / Climbing HOM 1f:3m - 1.00 FAILED - Not enough mutant or control data
A1cftm1b(EUCOMM)Hmgu JAX Tail Suspension / Climbing HOM 7f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
A1cftm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Forelimb nail - number HOM 8f:8m Fisher Exact Test framework 1.00 Success
A1cftm1b(EUCOMM)Hmgu JAX Electroretinography 2 / Rod a-wave implicit time HOM 2f:2m Not processed 1.00 FAILED - Not enough mutant or control data
A1cftm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Gait HOM 8f:8m Fisher Exact Test framework 1.00 Success
A1cftm1b(EUCOMM)Hmgu JAX Gross Pathology and Tissue Collection / Kidney HOM f:m Supplied as data Success
A1cftm1b(EUCOMM)Hmgu JAX Gross Pathology and Tissue Collection / Kidney HOM f:m Supplied as data Success
A1cftm1b(EUCOMM)Hmgu JAX Gross Pathology and Tissue Collection / Kidney HOM f:m Supplied as data Success
A1cftm1b(EUCOMM)Hmgu JAX Gross Pathology and Tissue Collection / Kidney HOM f:m Supplied as data Success
A1cftm1b(EUCOMM)Hmgu JAX Electrocardiogram (ECG) / QRS HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.567 Success
A1cftm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Ears HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
A1cftm1b(EUCOMM)Hmgu JAX Gross Pathology and Tissue Collection / Small intestine HOM f:m Supplied as data Success
A1cftm1b(EUCOMM)Hmgu JAX Gross Pathology and Tissue Collection / Small intestine HOM f:m Supplied as data Success
A1cftm1b(EUCOMM)Hmgu JAX Gross Pathology and Tissue Collection / Small intestine HOM f:m Supplied as data Success
A1cftm1b(EUCOMM)Hmgu JAX Gross Pathology and Tissue Collection / Small intestine HOM f:m Supplied as data Success
A1cftm1b(EUCOMM)Hmgu JAX Electroretinography 2 / Rod a-wave amplitude HOM 2f:2m Not processed 1.00 FAILED - Not enough mutant or control data
A1cftm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Tail - presence HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
A1cftm1b(EUCOMM)Hmgu JAX Insulin Blood Level / Insulin HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.657 Success
A1cftm1b(EUCOMM)Hmgu JAX Rotarod / Learning difference HOM 8f:8m Mixed Model framework, generalized least squares, equation withoutWeight 0.370 Success
A1cftm1b(EUCOMM)Hmgu JAX Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI4 HOM 1f:3m Not processed 1.00 FAILED - Not enough mutant measurements (1f/3m)
A1cftm1b(EUCOMM)Hmgu JAX Body Composition (DEXA lean/fat) / Lean mass HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.861 Success
A1cftm1b(EUCOMM)Hmgu JAX Eye Morphology / Pupil Light Response HOM 8f:8m Fisher Exact Test framework 1.00 Success
A1cftm1b(EUCOMM)Hmgu JAX Eye Morphology / Corneal opacity HOM 8f:8m Fisher Exact Test framework 1.00 Success
A1cftm1b(EUCOMM)Hmgu JAX Sleep Wake / Sleep bout lengths standard deviation HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0293 Success
A1cftm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Forelimb digit - number HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
A1cftm1b(EUCOMM)Hmgu JAX Electroretinography 2 / Rod a-wave amplitude-left HOM 2f:2m Not processed 1.00 FAILED - Not enough mutant or control data
A1cftm1b(EUCOMM)Hmgu JAX Gross Pathology and Tissue Collection / Eye with optic nerve HOM f:m Supplied as data Success
A1cftm1b(EUCOMM)Hmgu JAX Gross Pathology and Tissue Collection / Eye with optic nerve HOM f:m Supplied as data Success
A1cftm1b(EUCOMM)Hmgu JAX Gross Pathology and Tissue Collection / Eye with optic nerve HOM f:m Supplied as data Success
A1cftm1b(EUCOMM)Hmgu JAX Gross Pathology and Tissue Collection / Eye with optic nerve HOM f:m Supplied as data Success
A1cftm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Skin color - tail HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584) N/A
Aorta 2 No N/A
Brain 2 No  (2/2) N/A
Brainstem 2 No  (2/2) N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No N/A
Cerebellum 2 No  (2/2) N/A
Cerebral cortex 2 No N/A
Epididymis 2 No  (18/134) N/A
Esophagus 2 No  (7/415) N/A
Eye 2 No N/A
Heart 2 No N/A
Hippocampus 2 No N/A
Hypothalamus 2 No N/A
Kidney 2 No  (18/584)  (2/2) N/A
Large intestine 2 No  (10/584)  (2/2) N/A
Liver 2 No  (2/2) N/A
Lower urinary tract 2 No N/A
Lung 2 No N/A
Lymph node 2 No N/A
Mammary gland 2 No N/A
Midbrain 2 No N/A
Olfactory lobe 2 No N/A
Ovary 2 No  (1/584)  (1/2) N/A
Oviduct 2 No N/A
Pancreas 2 No  (5/584)  (2/2) N/A
Peripheral nervous system 2 No N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No N/A
Prostate gland 2 No  (12/584) N/A
Skeletal muscle 2 No N/A
Skin 2 No N/A
Small intestine 2 No  (9/584)  (2/2) N/A
Spinal cord 2 No N/A
Spleen 2 No  (2/584) N/A
Stomach 2 No  (12/584) N/A
Striatum 2 No N/A
Submandibular gland 2 No  (2/132)  (1/2) N/A
Testis 2 No  (2/584)  (1/2) N/A
Thalamus 2 No N/A
Thymus 2 No N/A
Thyroid gland 2 No  (15/584) N/A
Trachea 2 No N/A
Urinary bladder 2 No N/A
Uterus 2 No N/A
Vascular system 2 No N/A
Vesicular gland 2 No N/A
White adipose tissue 2 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2  (6/485) N/A
Dorsal root ganglion 2  (1/47) N/A
Ear 2  (1/485) N/A
Embryo 2  (1/485)  (2/3)  Wholemount images
Eye 2  (1/485) N/A
Foot 2  (1/485) N/A
Forebrain 2  (1/485) N/A
Forelimb 2  (1/485) N/A
Fronto-nasal process 2  (1/48) N/A
Hand 2  (1/485) N/A
Head 2  (5/485) N/A
Heart 2  (1/485) N/A
Hindbrain 2  (6/485) N/A
Hindlimb 2  (1/485) N/A
Liver 2  (1/485)  (2/3) N/A
Lung 2  (1/485) N/A
Mandibular process 2  (1/485) N/A
Maxillary process 2  (1/485) N/A
Midbrain 2  (1/485) N/A
Nose 2  (1/51) N/A
Oral cavity 2  (1/485) N/A
Skin 2  (1/485) N/A
Spinal cord 2  (1/50) N/A
Tail 2  (1/485) N/A
Tail somite 2  (1/485) N/A

 Associated Images

X-ray: XRay Images Dorso Ventral
10 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
10 Images
X-ray: XRay Images Lateral Orientation
10 Images
X-ray: XRay Images Skull Lateral Orientation
10 Images
X-ray: XRay Images Forepaw
10 Images
Sleep Wake: Wake state (bmp file)
16 Images
Embryo LacZ: LacZ images wholemount
12 Images
Electroretinography 2: Rod and cone PDF
4 Images
Combined SHIRPA and Dysmorphology
2 Images

 Disease Models

No associations by disease annotation and gene orthology found.
Please visit the desktop version to see this section

 Order Mouse and ES Cells

MGI Allele Allele Type Availability
A1cftm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
A1cftm1b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre) Mice

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