Gene: Fbxo7

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Name
F-box protein 7
MGI ID
MGI:1917004
Synonyms
2410015K21Rik A230052G17Rik
Viability
Embryo viewer
N/A
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
decreased hemoglobin content Fbxo7tm1a(EUCOMM)Wtsi HOM Early adult 6.38×10-15
decreased leukocyte cell number Fbxo7tm1a(EUCOMM)Wtsi HOM Early adult 1.90×10-06
thrombocytosis Fbxo7tm1a(EUCOMM)Wtsi HOM Early adult 1.01×10-09
increased circulating bilirubin level Fbxo7tm1a(EUCOMM)Wtsi HOM Early adult 1.02×10-09
increased mean corpuscular hemoglobin Fbxo7tm1a(EUCOMM)Wtsi HOM Early adult 2.86×10-07
decreased circulating fructosamine level Fbxo7tm1a(EUCOMM)Wtsi HOM Early adult 1.68×10-06
increased lean body mass Fbxo7tm1a(EUCOMM)Wtsi HOM Early adult 9.60×10-06
increased red blood cell distribution width Fbxo7tm1a(EUCOMM)Wtsi HOM Early adult 2.93×10-16
decreased erythrocyte cell number Fbxo7tm1a(EUCOMM)Wtsi HOM Early adult 3.41×10-19
decreased circulating iron level Fbxo7tm1a(EUCOMM)Wtsi HOM Early adult 2.40×10-34
increased mean platelet volume Fbxo7tm1a(EUCOMM)Wtsi HOM Early adult 1.24×10-11
decreased total body fat amount Fbxo7tm1a(EUCOMM)Wtsi HOM Early adult 6.19×10-05
decreased hematocrit Fbxo7tm1a(EUCOMM)Wtsi HOM Early adult 1.81×10-14
decreased circulating alanine transaminase level Fbxo7tm1a(EUCOMM)Wtsi HOM Early adult 1.56×10-05

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 Expression

Expression data not available

 Associated Images

X-ray: XRay Images Whole Body Dorso Ventral
15 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
14 Images
X-ray: XRay Images Whole Body Lateral Orientation
12 Images
Histopathology
37 Images
X-ray: XRay Images Forepaw
14 Images
X-ray: XRay Images Skull Lateral Orientation
13 Images
Legacy Phenotype Associated Images

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 Disease Models

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 Histopathology

Phenotype Allele Zygosity Sex Life Stage
Testes - process of degenerative change Fbxo7tm1a(EUCOMM)Wtsi HOM Early adult
Spleen - hyperplasia Fbxo7tm1a(EUCOMM)Wtsi HOM Early adult
Thymus - hypoplasia Fbxo7tm1a(EUCOMM)Wtsi HOM Early adult
Liver - hyperplasia Fbxo7tm1a(EUCOMM)Wtsi HOM Early adult
Eye with optic nerve - atrophy Fbxo7tm1a(EUCOMM)Wtsi HOM Early adult
Spleen - MPATH diagnostic term extramedullary hemopoiesis Fbxo7tm1a(EUCOMM)Wtsi HOM Early adult
Bone marrow - hyperplasia Fbxo7tm1a(EUCOMM)Wtsi HOM Early adult
Liver - MPATH diagnostic term extramedullary hemopoiesis Fbxo7tm1a(EUCOMM)Wtsi HOM Early adult

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MGI Allele Allele Type Produced
Fbxo7tm1b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre) Mice
Fbxo7tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Fbxo7tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells
Fbxo7tm1c(EUCOMM)Wtsi Wild type floxed exon (post-Flp) Mice

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