Not currently registered for phenotyping at IMPC

Phenotyping is currently not planned for a knockout strain of this gene.

Gene Summary

Name:
inositol polyphosphate multikinase
Synonyms:
2410017C19Rik

IMPC Data Collections

  • No Body Weight Data
  • No Embryo Imaging Data
  • No Viability Data

IMPC Phenotype Summary

Significant
Not Significant
Not tested

Phenotypes

The IMPC applies a panel of phenotyping screens to characterise single-gene knockout mice by comparison to wild types. Click on the different tabs to visualise significant phenotypes identified by the IMPC, as well as all data that was measured.

lacZ Expression

Expression data not available

Associated Images

Images submitted by IMPC centres for a selection of procedures. Each set of images is available to view in our image comparator.

Phenotype associated images not available

Human diseases caused by Ipmk mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.

No human diseases associated to this gene by orthology or annotation.

The table below shows human diseases predicted to be associated to Ipmk by phenotypic similarity.

Disease Similarity of
phenotypes
Matching phenotypes Source
Spina Bifida-Hypospadias Syndrome
Spinal dysraphism, Spina bifida ORPHA:3176
Neural Tube Defects, Folate-Sensitive
Spinal dysraphism OMIM:601634
Neural Tube Defects, X-Linked
Spina bifida, Anencephaly OMIM:301410
Anencephaly 1
Anencephaly, Spina bifida OMIM:206500
Frontal Encephalocele
Spina bifida, Encephalocele, Hydrocephalus ORPHA:1931
Acalvaria
Holoprosencephaly, Spina bifida, Hydrocephalus ORPHA:945
Ophthalmoplegia, External, And Myopia
Spina bifida OMIM:311000
Dysraphism-Cleft Lip/Palate-Limb Reduction Defects Syndrome
Anencephaly, Spina bifida ORPHA:2476
Camptodactyly With Muscular Hypoplasia, Skeletal Dysplasia, And Abnormal Palmar Creases
Spina bifida OMIM:211960
Fryns Microphthalmia Syndrome
Neural tube defect OMIM:600776
Craniorachischisis
Myelomeningocele, Cervical spina bifida, Anencephaly, Sirenomelia, Spinal dysraphism ORPHA:63260
Nevus Comedonicus Syndrome
Spina bifida occulta, Spina bifida ORPHA:64754
Schisis Association
Anencephaly, Spina bifida, Encephalocele ORPHA:63862
Chiari Malformation Type Ii
Myelomeningocele, Spina bifida, Cervical myelopathy, Hydrocephalus OMIM:207950
Caudal Duplication
Spina bifida, Myelomeningocele ORPHA:1756
Acropectorovertebral Dysplasia
Spina bifida ORPHA:957
Male Pseudohermaphroditism/Mental Retardation Syndrome, Verloes Type
Postnatal growth retardation, Cervical spina bifida, Growth delay OMIM:600122
Sirenomelia
Spina bifida, Sirenomelia ORPHA:3169
Blepharocheilodontic Syndrome 1
Neural tube defect OMIM:119580
Camptodactyly Syndrome, Guadalajara Type 1
Short stature, Spina bifida, Intrauterine growth retardation ORPHA:1327
Isolated Klippel-Feil Syndrome
Spina bifida ORPHA:2345
Anophthalmia Plus Syndrome
Spina bifida ORPHA:1104
Amish Lethal Microcephaly
Spina bifida ORPHA:99742
Cerebrocostomandibular Syndrome
Myelomeningocele, Intrauterine growth retardation, Hydranencephaly, Short stature, Spina bifida, ... ORPHA:1393
Czeizel-Losonci Syndrome
Spina bifida occulta, Spina bifida, Myelomeningocele, Hydrocephalus ORPHA:2437
Iniencephaly
Myelomeningocele, Rhizomelia, Anencephaly, Spinal dysraphism, Spina bifida, Hydrocephalus, Holopr... ORPHA:63259
Fountain Syndrome
Short stature, Spina bifida, Spina bifida occulta ORPHA:3219
Pelvis-Shoulder Dysplasia
Hydranencephaly, Short stature, Mesomelic/rhizomelic limb shortening, Spina bifida, Hydrocephalus... ORPHA:2839
Waardenburg Syndrome Type 1
Spina bifida, Meningocele ORPHA:894
Posterior Meningocele
Occipital meningocele, Lipomyelomeningocele, Neural tube defect, Hydrocephalus, Meningocele ORPHA:268810
Lung Agenesis-Heart Defect-Thumb Anomalies Syndrome
Spina bifida ORPHA:1120
Vacterl With Hydrocephalus
Intrauterine growth retardation, Spina bifida, Hydrocephalus, Aqueductal stenosis, Arrhinencephaly ORPHA:3412
Lumbar Syndrome
Spina bifida, Myelomeningocele ORPHA:83628
Trisomy 18
Intrauterine growth retardation, Anencephaly, Growth delay, Short stature, Spina bifida, Holopros... ORPHA:3380
Trisomy 20P
Umbilical hernia, Spina bifida ORPHA:261318
Mosaic Trisomy 9
Spina bifida, Intrauterine growth retardation ORPHA:99776
Waardenburg Syndrome, Type 1
Spina bifida, Myelomeningocele OMIM:193500
Pagod Syndrome
Short stature, Spina bifida, Meningocele, Encephalocele ORPHA:991
Neu-Laxova Syndrome
Spina bifida, Intrauterine growth retardation ORPHA:2671
Nail-Patella Syndrome
Short stature, Spina bifida OMIM:161200
Limb Body Wall Complex
Short umbilical cord, Myelomeningocele, Anencephaly, Spina bifida, Hydrocephalus, Spina bifida oc... ORPHA:2369
Cloacal Exstrophy
Spina bifida, Myelomeningocele ORPHA:93929
Neurofibromatosis, Type I
Short stature, Spina bifida, Aqueductal stenosis, Hydrocephalus OMIM:162200
Fibular Hemimelia
Spina bifida ORPHA:93323
Basal Cell Nevus Syndrome
Spina bifida, Hydrocephalus OMIM:109400
Neu-Laxova Syndrome 1
Short umbilical cord, Intrauterine growth retardation, Hydranencephaly, Spina bifida, Small place... OMIM:256520
Focal Dermal Hypoplasia
Umbilical hernia, Spina bifida ORPHA:2092
Hallermann-Streiff Syndrome
Proportionate short stature, Spina bifida OMIM:234100
Jacobsen Syndrome
Short stature, Growth delay, Spina bifida, Intrauterine growth retardation ORPHA:2308
22Q11.2 Deletion Syndrome
Occipital myelomeningocele, Intrauterine growth retardation, Short stature, Spina bifida, Hydroce... ORPHA:567
Thrombocytopenia-Absent Radius Syndrome
Short stature, Spina bifida OMIM:274000
Fanconi Anemia
Intrauterine growth retardation, Growth delay, Short stature, Spina bifida, Hydrocephalus, Umbili... ORPHA:84
Campomelic Dysplasia
Neonatal short-limb short stature, Spinal dysraphism, Spina bifida, Hydrocephalus, Disproportiona... OMIM:114290
Aicardi Syndrome
Postnatal growth retardation, Spina bifida OMIM:304050
Intellectual Disability-Cardiac Anomalies-Short Stature-Joint Laxity Syndrome
Short stature, Spina bifida ORPHA:508498
Vater/Vacterl Association
Intrauterine growth retardation, Occipital encephalocele, Patent urachus, Spina bifida, Postnatal... OMIM:192350
Koolen-De Vries Syndrome Due To A Point Mutation
Postnatal growth retardation, Spina bifida, Hydrocephalus ORPHA:363965
17Q21.31 Microdeletion Syndrome
Postnatal growth retardation, Spina bifida, Hydrocephalus ORPHA:363958
Neurodevelopmental Disorder With Dysmorphic Facies And Thin Corpus Callosum
Spina bifida OMIM:619480
Exstrophy-Epispadias Complex
Spina bifida, Hydrocephalus ORPHA:322
Split Cord Malformation
Myelomeningocele, Cervical spina bifida, Lipomyelomeningocele, Hydrocephalus, Meningocele ORPHA:573278

Histopathology

Summary table of phenotypes displayed during the Histopathology procedure which are considered significant. Full histopathology data table, including submitted images, can be accessed by clicking any row in this table.

There is no histopathology data for Ipmk

IMPC related publications

The table below lists publications which used either products generated by the IMPC or data produced by the phenotyping efforts of the IMPC. These publications have also been associated to Ipmk.

No publications found that use IMPC mice or data for Ipmk.

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MGI Allele Allele Type Produced
Ipmktm1e(EUCOMM)Wtsi Targeted, non-conditional allele ES Cells
Ipmktm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) ES Cells
Ipmktm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells

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