Not currently registered for phenotyping at IMPC
Phenotyping is currently not planned for a knockout strain of this gene.
Gene Summary
IMPC Data Collections
- No Body Weight Data
- No Embryo Imaging Data
- No Viability Data
Phenotyping is currently not planned for a knockout strain of this gene.
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
The table below lists publications which used either products generated by the IMPC or data produced by the phenotyping efforts of the IMPC. These publications have also been associated to Kansl2.
There are 3 publications which use IMPC produced mice or data.
Title | Journal | IMPC Allele | PubMed ID |
---|---|---|---|
Neural metabolic imbalance induced by MOF dysfunction triggers pericyte activation and breakdown of vasculature. | Nature cell biology (June 2020) | Kansl2tm1c(EUCOMM)Wtsi Kansl2tm1a(EUCOMM)Wtsi | 32541879 |
Temporal expression of MOF acetyltransferase primes transcription factor networks for erythroid fate. | Science advances (May 2020) | Kansl2tm1a(EUCOMM)Wtsi | PMC7314555 |
Evolutionary conserved NSL complex/BRD4 axis controls transcription activation via histone acetylation. | Nature communications (May 2020) | Kansl2tm1a(EUCOMM)Wtsi | PMC7206058 |
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MGI Allele | Allele Type | Produced |
---|---|---|
Kansl2tm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | Targeting vectors, ES Cells |
Kansl2tm1e(EUCOMM)Wtsi | Targeted, non-conditional allele | ES Cells |
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