Genes Phenotypes

Gene: Plekhm2

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Name
pleckstrin homology domain containing, family M (with RUN domain) member 2
MGI ID
MGI:1916832
Synonyms
2310034J19Rik
Viability
N/A
Embryo viewer
N/A
Other links
MGI   Ensembl  
Significant phenotypes (4) Measurements chart (259) All data table (433)
Expression & images (45) Disease models (0) Order (3)
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
decreased body weight Plekhm2tm1a(EUCOMM)Wtsi HOM Early adult 3.73×10-06
decreased hemoglobin content Plekhm2tm1a(EUCOMM)Wtsi HOM Early adult 3.23×10-07
increased leukocyte cell number Plekhm2tm1a(EUCOMM)Wtsi HOM Early adult 1.58×10-06
decreased hematocrit Plekhm2tm1a(EUCOMM)Wtsi HOM Early adult 2.84×10-06

Download data as:  TSV  XLS

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Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584)  (2/2) N/A
Aorta 2 No N/A
Blood vessel 2 No  (2/2) N/A
Bone 2 No  (2/2) N/A
Brain 2 No  (2/2) N/A
Brainstem 2 No N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No  (2/2) N/A
Cerebellum 2 No N/A
Cerebral cortex 2 No N/A
Eye 2 No  (2/2) N/A
Gall bladder 2 No  (2/2) N/A
Heart 2 No  (2/2) N/A
Hippocampus 2 No N/A
Hypothalamus 2 No N/A
Kidney 2 No  (18/584)  (2/2) N/A
Large intestine 2 No  (10/584)  (2/2) N/A
Liver 2 No N/A
Lower urinary tract 2 No  (2/2) N/A
Lung 2 No  (2/2) N/A
Lymph node 2 No  (2/2) N/A
Mammary gland 2 No  (2/2) N/A
Esophagus 2 No  (2/2) N/A
Olfactory lobe 2 No N/A
Ovary 2 No  (1/584)  (1/2) N/A
Oviduct 2 No  (1/2) N/A
Pancreas 2 No  (5/584)  (2/2) N/A
Parathyroid gland 2 No  (2/2) N/A
Peripheral nervous system 2 No  (2/2) N/A
Peyer's patch 2 No  (1/2) N/A
Pituitary gland 2 No  (1/2) N/A
Prostate gland 2 No  (12/584)  (1/2) N/A
Skeletal muscle tissue 2 No  (2/2) N/A
Skin 2 No  (2/2) N/A
Small intestine 2 No  (9/584)  (2/2) N/A
Spinal cord 2 No  (2/2) N/A
Spleen 2 No  (2/584)  (2/2) N/A
Stomach 2 No  (12/584)  (2/2) N/A
Striatum 2 No N/A
Testis 2 No  (2/584)  (1/2) N/A
Thymus 2 No  (2/2) N/A
Thyroid gland 2 No  (15/584)  (2/2) N/A
Trachea 2 No  (2/2) N/A
Uterus 2 No  (1/2) N/A
White adipose tissue 2 No  (1/2) N/A
LacZ Wholemount Images
LacZ Section Images
LacZ Section Images
Plekhm2tm1a(EUCOMM)Wtsi
testis, HET, Male, WTSI
Plekhm2tm1a(EUCOMM)Wtsi
lymph node, HET, Female, WTSI
Plekhm2tm1a(EUCOMM)Wtsi
thymus, HET, Female, WTSI
Plekhm2tm1a(EUCOMM)Wtsi
kidney, HET, Female, WTSI
Plekhm2tm1a(EUCOMM)Wtsi
brain, HET, Female, WTSI

View all 27 images

Plekhm2tm1a(EUCOMM)Wtsi
testis, HET, Male, WTSI
Plekhm2tm1a(EUCOMM)Wtsi
thymus, HET, Female, WTSI
Plekhm2tm1a(EUCOMM)Wtsi
kidney, HET, Female, WTSI
Plekhm2tm1a(EUCOMM)Wtsi
small intestine, peyer's patch, HET, Female, WTSI
Plekhm2tm1a(EUCOMM)Wtsi
spleen, HET, Female, WTSI

View all 17 images

Plekhm2tm1a(EUCOMM)Wtsi
small intestine, peyer's patch, HET, Female, WTSI
Plekhm2tm1a(EUCOMM)Wtsi
oesophagus, HET, Female, WTSI
Plekhm2tm1a(EUCOMM)Wtsi
large intestine, HET, Female, WTSI
Plekhm2tm1a(EUCOMM)Wtsi
gall bladder, HET, Female, WTSI
Plekhm2tm1a(EUCOMM)Wtsi
lymph node, HET, Female, WTSI
Plekhm2tm1a(EUCOMM)Wtsi
thymus, HET, Female, WTSI
Plekhm2tm1a(EUCOMM)Wtsi
small intestine, peyer's patch, HET, Female, WTSI
Plekhm2tm1a(EUCOMM)Wtsi
spleen, HET, Female, WTSI
Plekhm2tm1a(EUCOMM)Wtsi
brain, HET, Female, WTSI
Plekhm2tm1a(EUCOMM)Wtsi
brain, HET, Female, WTSI
Plekhm2tm1a(EUCOMM)Wtsi
peripheral nervous system, pituitary gland, HET, Female, WTSI
Plekhm2tm1a(EUCOMM)Wtsi
spinal cord, HET, Male, WTSI
Plekhm2tm1a(EUCOMM)Wtsi
mammary gland, white adipose tissue, HET, Female, WTSI
Plekhm2tm1a(EUCOMM)Wtsi
skeletal muscle tissue, blood vessel, cartilage tissue, bone, HET, Female, WTSI
Plekhm2tm1a(EUCOMM)Wtsi
skeletal muscle tissue, cartilage tissue, bone, HET, Female, WTSI
Plekhm2tm1a(EUCOMM)Wtsi
kidney, HET, Female, WTSI
Plekhm2tm1a(EUCOMM)Wtsi
urinary bladder, lower urinary tract, HET, Female, WTSI
Plekhm2tm1a(EUCOMM)Wtsi
lower urinary tract, urinary bladder, HET, Male, WTSI
Plekhm2tm1a(EUCOMM)Wtsi
heart, HET, Female, WTSI
Plekhm2tm1a(EUCOMM)Wtsi
skeletal muscle tissue, blood vessel, cartilage tissue, bone, HET, Female, WTSI
Plekhm2tm1a(EUCOMM)Wtsi
thyroid gland, trachea, parathyroid gland, HET, Female, WTSI
Plekhm2tm1a(EUCOMM)Wtsi
adrenal gland, HET, Female, WTSI
Plekhm2tm1a(EUCOMM)Wtsi
skin, HET, Female, WTSI
Plekhm2tm1a(EUCOMM)Wtsi
mammary gland, white adipose tissue, HET, Female, WTSI
Plekhm2tm1a(EUCOMM)Wtsi
skeletal muscle tissue, blood vessel, cartilage tissue, bone, HET, Female, WTSI
Plekhm2tm1a(EUCOMM)Wtsi
skeletal muscle tissue, cartilage tissue, bone, HET, Female, WTSI
Plekhm2tm1a(EUCOMM)Wtsi
testis, HET, Male, WTSI
Plekhm2tm1a(EUCOMM)Wtsi
uterus, oviduct, ovary, HET, Female, WTSI
Plekhm2tm1a(EUCOMM)Wtsi
thyroid gland, trachea, parathyroid gland, HET, Female, WTSI
Plekhm2tm1a(EUCOMM)Wtsi
lung, HET, Female, WTSI
Plekhm2tm1a(EUCOMM)Wtsi
mammary gland, white adipose tissue, HET, Female, WTSI
Plekhm2tm1a(EUCOMM)Wtsi
mammary gland, white adipose tissue, HET, Female, WTSI
Plekhm2tm1a(EUCOMM)Wtsi
eye, HET, Female, WTSI
No Embryo expression data was found for this gene.

 Associated Images

Legacy Phenotype Associated Images
Plekhm2tm1a(EUCOMM)Wtsi
head, HOM, Female, WTSI
Plekhm2tm1a(EUCOMM)Wtsi
forearm, HOM, Female, WTSI
Plekhm2tm1a(EUCOMM)Wtsi
body, HOM, Female, WTSI
Plekhm2tm1a(EUCOMM)Wtsi
head, HOM, Female, WTSI
Plekhm2tm1a(EUCOMM)Wtsi
forearm, HOM, Female, WTSI

View all 132 images

Plekhm2tm1a(EUCOMM)Wtsi
back skin, HOM, Female, WTSI
Plekhm2tm1a(EUCOMM)Wtsi
back skin, HOM, Female, WTSI

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Plekhm2tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Plekhm2tm44411(L1L2_gt1_Del_LacZ) Targeting vectors
Plekhm2tm44411(pL1L2_frt15_BetactinBSD_frt14_neo_Rox) Targeting vectors

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