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Gene: Slc38a4 MGI:1916604

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Registered for phenotyping at IMPC

Phenotyping is planned for a knockout strain of this gene but data is not currently available.

Gene Summary

Name:
solute carrier family 38, member 4
Synonyms:
1110012E16Rik,  SNAT4,  1700012A18Rik,  Ata3

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IMPC Data Collections

  • No Body Weight Data
  • No Embryo Imaging Data
  • No Viability Data

IMPC Phenotype Summary

Significant
Not Significant
Not tested

View all our phenotype data below

Phenotypes

The IMPC applies a panel of phenotyping screens to characterise single-gene knockout mice by comparison to wild types. Click on the different tabs to visualise significant phenotypes identified by the IMPC, as well as all data that was measured.

lacZ Expression

Expression data not available

Associated Images

Images submitted by IMPC centres for a selection of procedures. Each set of images is available to view in our image comparator.

Phenotype associated images not available

Human diseases caused by Slc38a4 mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.

No human diseases associated to this gene by orthology or annotation.

The table below shows human diseases predicted to be associated to Slc38a4 by phenotypic similarity.

Disease Similarity of
phenotypes		 Matching phenotypes Source
Placental Insufficiency
Abnormal placenta morphology, Abnormal umbilical cord blood vessel morphology, Small for gestatio... ORPHA:439167
Growth Delay Due To Insulin-Like Growth Factor Type 1 Deficiency
Small for gestational age, Truncal obesity, Severe intrauterine growth retardation, Small placent... ORPHA:73272
Histidinemia
Histidinuria, Hyperhistidinemia ORPHA:2157
Silver-Russell Syndrome Due To A Point Mutation
Intrauterine growth retardation, Small for gestational age, Small placenta, Oligohydramnios ORPHA:397590
Histidinemia
Histidinuria, Hyperhistidinemia OMIM:235800
Kagami-Ogata Syndrome Due To Maternal 14Q32.2 Hypermethylation
Small for gestational age, Polyhydramnios, Large for gestational age, Large placenta, Umbilical h... ORPHA:254534
Immunodeficiency, Developmental Delay, And Hypohomocysteinemia
Decreased serum creatinine, Intrauterine growth retardation, Failure to thrive OMIM:617744
Fetal Akinesia Deformation Sequence 1
Decreased fetal movement, Premature birth, Nonimmune hydrops fetalis, Polyhydramnios, Fetal akine... OMIM:208150
Hereditary Arterial And Articular Multiple Calcification Syndrome
Decreased serum creatinine ORPHA:289601
Neu-Laxova Syndrome 1
Decreased fetal movement, Spina bifida, Polyhydramnios, Fetal akinesia sequence, Stillbirth, Shor... OMIM:256520
Restrictive Dermopathy
Decreased fetal movement, Premature birth, Premature delivery because of cervical insufficiency o... ORPHA:1662
Nephrogenic Syndrome Of Inappropriate Antidiuresis
Decreased serum creatinine OMIM:300539
Kagami-Ogata Syndrome Due To Maternal 14Q32.2 Microdeletion
Umbilical hernia, Large placenta, Polyhydramnios, Intrauterine growth retardation ORPHA:254528
Trichohepatoenteric Syndrome 1
Small for gestational age, Polyhydramnios, Large placenta, Abnormalities of placenta or umbilical... OMIM:222470
Mosaic Trisomy 16
Small for gestational age, Premature birth, Large placenta, Single umbilical artery, Intrauterine... ORPHA:1708
Kagami-Ogata Syndrome
Large placenta, Premature birth, Polyhydramnios, Large for gestational age ORPHA:254519
Greenberg Dysplasia
Nonimmune hydrops fetalis, Polyhydramnios, Echogenic fetal bowel, Large placenta, Increased nucha... OMIM:215140
Restrictive Dermopathy 1
Spontaneous chorioamniotic separation, Decreased fetal movement, Premature birth, Polyhydramnios,... OMIM:275210
Meckel Syndrome, Type 1
Occipital encephalocele, Breech presentation, Large placenta, Anencephaly, Single umbilical arter... OMIM:249000
Beckwith-Wiedemann Syndrome
Premature birth, Polyhydramnios, Large for gestational age, Large placenta, Subchorionic septal c... ORPHA:116
Kagami-Ogata Syndrome Due To Paternal Uniparental Disomy Of Chromosome 14
Premature birth, Polyhydramnios, Large for gestational age, Large placenta, Spinal dysraphism, In... ORPHA:96334

Histopathology

Summary table of phenotypes displayed during the Histopathology procedure which are considered significant. Full histopathology data table, including submitted images, can be accessed by clicking any row in this table.

There is no histopathology data for Slc38a4

IMPC related publications

The table below lists publications which used either products generated by the IMPC or data produced by the phenotyping efforts of the IMPC. These publications have also been associated to Slc38a4.

No publications found that use IMPC mice or data for Slc38a4.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.

MGI Allele Allele Type Produced
Slc38a4tm1e(EUCOMM)Wtsi Targeted, non-conditional allele ES Cells
Slc38a4tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Slc38a4tm1e(EUCOMM)Hmgu Targeted, non-conditional allele ES Cells
Slc38a4tm83351(L1L2_Pgk_P) KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors

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