IMPC Data Collections
- Body Weight Measurements
- No Embryo Imaging Data
- Viability Data
The IMPC applies a panel of phenotyping screens to characterise single-gene knockout mice by comparison to wild types. Click on the different tabs to visualise significant phenotypes identified by the IMPC, as well as all data that was measured.
Images submitted by IMPC centres for a selection of procedures. Each set of images is available to view in our image comparator.
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
The table below shows human diseases predicted to be associated to Oscp1 by phenotypic similarity.
|Erythrocytosis, Familial, 7||
||Increased hematocrit, Polycythemia||OMIM:617981|
|Erythrocytosis, Familial, 3||
||Increased hematocrit, Increased red blood cell mass, Increased hemoglobin||OMIM:609820|
|Erythrocytosis, Familial, 6||
||Increased hematocrit, Increased hemoglobin, Polycythemia||OMIM:617980|
|Erythrocytosis, Familial, 8||
||Increased hematocrit, Splenomegaly, Increased hemoglobin, Polycythemia||OMIM:222800|
|Erythrocytosis, Familial, 5||
||Increased hematocrit, Increased hemoglobin, Polycythemia||OMIM:617907|
|Erythrocytosis, Familial, 4||
||Increased hematocrit, Increased hemoglobin, Polycythemia||OMIM:611783|
|Anemia, Sideroblastic, 5||
||Anemia, Reduced hematocrit, Hypochromic microcytic anemia, Thrombocytopenia, Neutropenia||OMIM:619523|
||Increased red blood cell mass, Increased hematocrit, Thrombocytosis, Leukocytosis, Thrombocytopen...||OMIM:263300|
|Erythrocytosis, Familial, 1||
||Increased hematocrit, Increased red blood cell mass, Increased hemoglobin, Splenomegaly||OMIM:133100|
|Anemia, Congenital Dyserythropoietic, Type Iv||
||Anemia, Reduced hematocrit, Hemolytic anemia, Circulating nucleated red blood cells, Erythroid hy...||OMIM:613673|
|Erythrocytosis, Familial, 2||
||Increased hematocrit, Increased red blood cell mass, Increased hemoglobin||OMIM:263400|
||Increased hematocrit, Polycythemia||ORPHA:284227|
||Anemia, Abnormal hemoglobin, Microcytic anemia||ORPHA:231237|
|Dyserythropoiesis, Congenital, With Ultrastructurally Normal Erythroblast Heterochromatin||
||Anisocytosis, Anemia of inadequate production, Oval macrocytosis, Poikilocytosis||OMIM:603529|
||Increased mean corpuscular hemoglobin concentration, Increased red blood cell count, Increased he...||ORPHA:90041|
|Duodenal Neuroendocrine Tumor||
||Increased hematocrit, Iron deficiency anemia, Insulinoma, Elevated circulating growth hormone con...||ORPHA:100076|
|Acute Interstitial Pneumonia||
|Tubulointerstitial Nephritis And Uveitis Syndrome||
||Normocytic anemia, Reduced hematocrit, Normochromic anemia||ORPHA:91500|
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|MGI Allele||Allele Type||Produced|
|Oscp1tm1b(EUCOMM)Hmgu||Reporter-tagged deletion allele (with selection cassette)||Mice|
|Oscp1tm1a(EUCOMM)Hmgu||KO first allele (reporter-tagged insertion with conditional potential)||Mice, Targeting vectors, ES Cells|
|Oscp1tm1e(EUCOMM)Hmgu||Targeted, non-conditional allele||ES Cells|
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