Trappc2l | trafficking protein particle complex 2L

GeneMGI:1916295Synonyms: Tca17, 1810017G16Rik

Physiological systems

20 / 24 physiological systems tested

9 Significantly impacted by the knock-out

 Reproductive system Immune system Endocrine/exocrine gland Growth/size/body region Nervous system Hematopoietic system Behavior/neurological Skeleton Cardiovascular system

11 No significant impact

4 Not tested

Gene metrics:18Significant phenotypes
1Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased heart weight2 supporting datasetsTrappc2lem1(IMPC)MbphomozygoteEarly adult2.86x10-10 
abnormal bone structure1 supporting datasetTrappc2lem1(IMPC)MbphomozygoteEarly adult4.06x10-6 
decreased bone mineral content2 supporting datasetsTrappc2lem1(IMPC)MbphomozygoteEarly adult3.4x10-10 
enlarged spleen2 supporting datasetsTrappc2lem1(IMPC)MbphomozygoteEarly adultN/A * 
small testis1 supporting datasetTrappc2lem1(IMPC)MbphomozygoteEarly adultN/A * 
abnormal testis morphology1 supporting datasetTrappc2lem1(IMPC)MbphomozygoteEarly adultN/A * 
decreased prepulse inhibition2 supporting datasetsTrappc2lem1(IMPC)MbphomozygoteEarly adult1.31x10-8 
decreased body length1 supporting datasetTrappc2lem1(IMPC)MbphomozygoteEarly adult3.55x10-5 
increased mean platelet volume1 supporting datasetTrappc2lem1(IMPC)MbphomozygoteEarly adult2.28x10-5 
female infertility1 supporting datasetTrappc2lem1(IMPC)MbphomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* Does not have a P-value assigned because it was manually marked as significant.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Trappc2lem1(IMPC)MbpExon Deletionmouse
Trappc2ltm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell

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