Mtmr14 | myotubularin related protein 14

GeneMGI:1916075Synonyms: 1110061O04Rik

Physiological systems

20 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Homeostasis/metabolism Behavior/neurological

18 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Viability data
Body weight measurements
Embryo imaging data
Gene metrics:5Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased startle reflex4 supporting datasetsMtmr14tm1a(KOMP)WtsihomozygoteEarly adult5.67x10-6 
increased circulating aspartate transaminase level1 supporting datasetMtmr14tm1a(KOMP)WtsihomozygoteEarly adult5.47x10-5 
increased lactate dehydrogenase level1 supporting datasetMtmr14tm1a(KOMP)WtsihomozygoteEarly adult3.37x10-5 
increased circulating amylase level1 supporting datasetMtmr14tm1a(KOMP)WtsihomozygoteEarly adult8.02x10-5 
increased circulating alanine transaminase level1 supporting datasetMtmr14tm1a(KOMP)WtsihomozygoteEarly adult6.76x10-9 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Mtmr14tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Mtmr14tm1e(KOMP)WtsiTargeted, non-conditional alleleES Cell

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