Gene: Rab3gap2

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Name
RAB3 GTPase activating protein subunit 2
MGI ID
MGI:1916043
Synonyms
1110059F07Rik
View
N/A
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
decreased heart rate Rab3gap2tm1b(KOMP)Wtsi HOM postnatal 1.78×10-07
decreased body length Rab3gap2tm1b(KOMP)Wtsi HOM postnatal 1.22×10-07
increased circulating bilirubin level Rab3gap2tm1b(KOMP)Wtsi HOM postnatal 6.11×10-05
decreased bone mineral density Rab3gap2tm1b(KOMP)Wtsi HOM postnatal 1.41×10-08
narrow eye opening Rab3gap2tm1b(KOMP)Wtsi HOM postnatal 1.13×10-05
cataract Rab3gap2tm1b(KOMP)Wtsi HOM postnatal 6.94×10-05
prolonged RR interval Rab3gap2tm1b(KOMP)Wtsi HOM postnatal 2.02×10-07
persistence of hyaloid vascular system Rab3gap2tm1b(KOMP)Wtsi HOM postnatal 7.16×10-05
abnormal behavior Rab3gap2tm1b(KOMP)Wtsi HOM postnatal 1.13×10-05
decreased lean body mass Rab3gap2tm1b(KOMP)Wtsi HOM postnatal 4.47×10-06
abnormal optic disk morphology Rab3gap2tm1b(KOMP)Wtsi HOM postnatal 2.17×10-05
hyperactivity Rab3gap2tm1b(KOMP)Wtsi HOM postnatal 6.30×10-08
decreased bone mineral content Rab3gap2tm1b(KOMP)Wtsi HOM postnatal 2.19×10-06
decreased total body fat amount Rab3gap2tm1b(KOMP)Wtsi HOM postnatal 1.55×10-06

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 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584)  Section images
Aorta 2 No  (2/2)  Section images
Brain 2 No  Section images
Brainstem 2 No N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No N/A
Cerebellum 2 No N/A
Cerebral cortex 2 No N/A
Epididymis 2 No  (18/134)  (1/2)  Section images
Esophagus 2 No  (7/415)  (2/2)  Section images
Eye 2 No N/A
Heart 2 No N/A
Hippocampus 2 No N/A
Hypothalamus 2 No N/A
Kidney 2 No  (18/584)  (2/2)  Section images
Large intestine 2 No  (10/584)  (2/2)  Section images
Liver 2 No N/A
Lower urinary tract 2 No N/A
Lung 2 No N/A
Lymph node 2 No N/A
Mammary gland 2 No N/A
Midbrain 2 No N/A
Olfactory lobe 2 No N/A
Ovary 2 No  (1/584)  (1/2)  Section images
Oviduct 2 No  Section images
Pancreas 2 No  (5/584)  (2/2)  Section images
Peripheral nervous system 2 No N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No  Section images
Prostate gland 2 No  (12/584) N/A
Skeletal muscle 2 No N/A
Skin 2 No  (2/2)  Section images
Small intestine 2 No  (9/584) N/A
Spinal cord 2 No N/A
Spleen 2 No  (2/584) N/A
Stomach 2 No  (12/584)  (2/2)  Section images
Striatum 2 No N/A
Submandibular gland 2 No  (2/132)  (2/2)  Section images
Testis 2 No  (2/584)  (1/2)  Section images
Thalamus 2 No N/A
Thymus 2 No N/A
Thyroid gland 2 No  (15/584)  (2/2)  Section images
Trachea 2 No N/A
Urinary bladder 2 No  Section images
Uterus 2 No N/A
Vascular system 2 No  (2/2)  Section images
Vesicular gland 2 No N/A
White adipose tissue 2 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 1  (6/485) N/A
Dorsal root ganglion 1  (1/47) N/A
Ear 1  (1/485) N/A
Embryo 1  (1/485) N/A
Eye 1  (1/485) N/A
Foot 1  (1/485) N/A
Forebrain 1  (1/485) N/A
Forelimb 1  (1/485) N/A
Fronto-nasal process 1  (1/48) N/A
Hand 1  (1/485) N/A
Head 1  (5/485) N/A
Heart 1  (1/485) N/A
Hindbrain 1  (6/485) N/A
Hindlimb 1  (1/485) N/A
Liver 1  (1/485) N/A
Lung 1  (1/485) N/A
Mandibular process 1  (1/485) N/A
Maxillary process 1  (1/485) N/A
Midbrain 1  (1/485) N/A
Nose 1  (1/51) N/A
Oral cavity 1  (1/485) N/A
Skin 1  (1/485) N/A
Spinal cord 1  (1/50) N/A
Tail 1  (1/485) N/A
Tail somite 1  (1/485) N/A

 Associated Images

Electroretinography 2: Rod and cone PDF
2 Images
X-ray: XRay Images Skull Lateral Orientation
10 Images
X-ray: XRay Images Forepaw
10 Images
X-ray: XRay Images Lateral Orientation
10 Images
Original Image
Adult LacZ: LacZ Images Section
18 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
10 Images
X-ray: XRay Images Dorso Ventral
10 Images

 Disease Models

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 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Rab3gap2tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Rab3gap2tm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre) Mice

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