Trp53inp2 | transformation related protein 53 inducible nuclear protein 2

GeneMGI:1915978Synonyms: Tp53inp2, 1110029F20Rik

Physiological systems

20 / 24 physiological systems tested

9 Significantly impacted by the knock-out

 Reproductive system Immune system Integument Endocrine/exocrine gland Growth/size/body region Nervous system Vision/eye Liver/biliary system Renal/urinary system

11 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:14Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal kidney morphology2 supporting datasetsTrp53inp2em1(IMPC)MbphomozygoteEarly adultN/A * 
cataract1 supporting datasetTrp53inp2em1(IMPC)MbphomozygoteEarly adult2.8x10-7 
abnormal testis morphology1 supporting datasetTrp53inp2em1(IMPC)MbphomozygoteEarly adultN/A * 
enlarged testis1 supporting datasetTrp53inp2em1(IMPC)MbphomozygoteEarly adultN/A * 
small kidney2 supporting datasetsTrp53inp2em1(IMPC)MbphomozygoteEarly adultN/A * 
abnormal skin morphology1 supporting datasetTrp53inp2em1(IMPC)MbphomozygoteEarly adultN/A * 
abnormal eye morphology1 supporting datasetTrp53inp2em1(IMPC)MbphomozygoteEarly adultN/A * 
abnormal lymph node morphology1 supporting datasetTrp53inp2em1(IMPC)MbphomozygoteEarly adultN/A * 
decreased prepulse inhibition3 supporting datasetsTrp53inp2em1(IMPC)MbphomozygoteEarly adult8.32x10-5 
enlarged lymph nodes1 supporting datasetTrp53inp2em1(IMPC)MbphomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Trp53inp2em1(IMPC)MbpExon Deletionmouse
Trp53inp2tm1a(KOMP)MbpKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Trp53inp2tm1e(KOMP)MbpTargeted, non-conditional alleleES Cell

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