Gene Summary

Name:
secretoglobin, family 3A, member 1
Synonyms:
LuLeu2,  HIN-1,  1110030K16Rik,  UGRP2

IMPC Data Collections

IMPC Phenotype Summary

Significant
Not Significant
Not tested

Phenotypes

The IMPC applies a panel of phenotyping screens to characterise single-gene knockout mice by comparison to wild types. Click on the different tabs to visualise significant phenotypes identified by the IMPC, as well as all data that was measured.

Select physiological systems to view:
Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

lacZ Expression

Expression data not available

Associated Images

Images submitted by IMPC centres for a selection of procedures. Each set of images is available to view in our image comparator.

Phenotype associated images not available

Human diseases caused by Scgb3a1 mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.

No human diseases associated to this gene by orthology or annotation.

The table below shows human diseases predicted to be associated to Scgb3a1 by phenotypic similarity.

Disease Similarity of
phenotypes
Matching phenotypes Source
Ciliary Dyskinesia With Transposition Of Ciliary Microtubules
Abnormal respiratory motile cilium morphology OMIM:215520
Spermatogenic Failure 38
Abnormal axonemal organization of respiratory motile cilia, Tapered sperm head, Abnormal sperm he... OMIM:618433
Ciliary Dyskinesia, Primary, 6
Absent/shortened outer dynein arms, Abnormal respiratory motile cilium morphology OMIM:610852
Ciliary Dyskinesia, Primary, 50
Short sperm flagella, Absent inner dynein arms, Coiled sperm flagella OMIM:620356
Ciliary Dyskinesia, Primary, 48, Without Situs Inversus
Absent central microtubular pair morphology of respiratory motile cilia OMIM:620032
Ciliary Dyskinesia, Primary, 10
Abnormal respiratory motile cilium morphology OMIM:612518
Ciliary Dyskinesia With Defective Radial Spokes
Nasal polyposis, Absent respiratory ciliary axoneme radial spokes OMIM:242670
Ciliary Dyskinesia, Primary, 13
Absent outer dynein arms, Absent inner dynein arms OMIM:613193
Familial Nasal Acilia
Abnormal respiratory motile cilium morphology ORPHA:922
Ectodermal Dysplasia, Hypohidrotic, With Hypothyroidism And Ciliary Dyskinesia
Abnormal respiratory motile cilium morphology OMIM:225050
Ciliary Dyskinesia, Primary, 34
Absent central microtubular pair morphology of respiratory motile cilia OMIM:617091
Ciliary Dyskinesia, Primary, 45
Absent inner and outer dynein arms OMIM:618801
Ciliary Dyskinesia, Primary, 17
Dynein arm defect of respiratory motile cilia OMIM:614679
Ciliary Dyskinesia, Primary, 7
Abnormal axonemal organization of respiratory motile cilia OMIM:611884
Ciliary Dyskinesia, Primary, 28
Dynein arm defect of respiratory motile cilia OMIM:615505
Ciliary Dyskinesia, Primary, 11
Abnormal central microtubular pair morphology of respiratory motile cilia OMIM:612649
Ciliary Dyskinesia, Primary, 32
Absent respiratory ciliary axoneme radial spokes OMIM:616481
Ciliary Dyskinesia, Primary, 14
Abnormal axonemal organization of respiratory motile cilia, Absent inner dynein arms OMIM:613807
Ciliary Dyskinesia, Primary, 18
Absent inner dynein arms, Absent outer dynein arms OMIM:614874
Ciliary Dyskinesia, Primary, 16
Absent outer dynein arms OMIM:614017
Ciliary Dyskinesia, Primary, 12
Abnormal central microtubular pair morphology of respiratory motile cilia OMIM:612650
Ciliary Dyskinesia, Primary, 15
Abnormal axonemal organization of respiratory motile cilia, Nasal polyposis OMIM:613808
Ciliary Dyskinesia, Primary, 9
Absent outer dynein arms OMIM:612444
Ciliary Dyskinesia, Primary, 40
Azoospermia, Absent outer dynein arms OMIM:618300
Ciliary Dyskinesia, Primary, 30
Nasal polyposis, Absent outer dynein arms OMIM:616037
Ciliary Dyskinesia, Primary, 26
Absent outer dynein arms OMIM:615500
Ciliary Dyskinesia, Primary, 38
Absent inner and outer dynein arms OMIM:618063
Ciliary Dyskinesia, Primary, 19
Nasal polyposis, Absent inner and outer dynein arms OMIM:614935
Ciliary Dyskinesia, Primary, 2
Nasal polyposis, Absent inner and outer dynein arms OMIM:606763
Ciliary Dyskinesia, Primary, 22
Nasal polyposis, Absent inner and outer dynein arms OMIM:615444
Ciliary Dyskinesia, Primary, 1
Nasal polyposis, Absent outer dynein arms OMIM:244400
Ciliary Dyskinesia, Primary, 20
Absent outer dynein arms OMIM:615067

Histopathology

Summary table of phenotypes displayed during the Histopathology procedure which are considered significant. Full histopathology data table, including submitted images, can be accessed by clicking any row in this table.

There is no histopathology data for Scgb3a1

IMPC related publications

The table below lists publications which used either products generated by the IMPC or data produced by the phenotyping efforts of the IMPC. These publications have also been associated to Scgb3a1.

No publications found that use IMPC mice or data for Scgb3a1.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.

MGI Allele Allele Type Produced
Scgb3a1em1(IMPC)Bay Exon Deletion Mice
Scgb3a1tm1(KOMP)Wtsi Reporter-tagged deletion allele (with selection cassette) Targeting vectors, ES Cells

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