Gene: Nadk2

Name
NAD kinase 2, mitochondrial
MGI ID
MGI:1915896
Synonyms
4933430B08Rik MNADK 1110020G09Rik Nadkd1
View
N/A
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
hyperactivity Nadk2em1(IMPC)J HET postnatal 3.55×10-07
abnormal coat/hair pigmentation Nadk2tm1b(EUCOMM)Wtsi HET postnatal 3.34×10-05
abnormal embryo turning Nadk2em1(IMPC)J HOM embryonic day 9.5 0.00
preweaning lethality, complete penetrance Nadk2em1(IMPC)J HOM n/a 0.00
improved glucose tolerance Nadk2tm1b(EUCOMM)Wtsi HET postnatal 3.23×10-06
persistence of hyaloid vascular system Nadk2em1(IMPC)J HET postnatal 1.77×10-05
abnormal behavior Nadk2em1(IMPC)J HET postnatal 3.03×10-05
preweaning lethality, complete penetrance Nadk2tm1b(EUCOMM)Wtsi HOM n/a 0.00
decreased food intake Nadk2tm1b(EUCOMM)Wtsi HET postnatal 2.47×10-08
embryonic lethality prior to tooth bud stage Nadk2em1(IMPC)J HOM embryonic day 12.5 0.00

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Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584) N/A
Aorta 2 No  (2/2) N/A
Blood vessel 2 No N/A
Bone 2 No  (2/2) N/A
Brain 2 No  (2/2) N/A
Brainstem 2 No  (2/2) N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No  (2/2) N/A
Cerebellum 2 No  (2/2) N/A
Cerebral cortex 2 No  (1/2) N/A
Eye 2 No N/A
Gall bladder 2 No  (1/2) N/A
Heart 2 No  (2/2) N/A
Hippocampus 2 No  (2/2) N/A
Hypothalamus 2 No  (2/2) N/A
Kidney 2 No  (18/584)  (2/2) N/A
Large intestine 2 No  (10/584) N/A
Liver 2 No  (2/2) N/A
Lower urinary tract 2 No  (2/2) N/A
Lung 2 No  (1/2) N/A
Lymph node 2 No N/A
Mammary gland 2 No N/A
Esophagus 2 No N/A
Olfactory lobe 2 No  (2/2) N/A
Ovary 2 No  (1/584)  (1/2) N/A
Oviduct 2 No  (1/2) N/A
Pancreas 2 No  (5/584)  (2/2) N/A
Parathyroid gland 2 No  (2/2) N/A
Peripheral nervous system 2 No  (2/2) N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No  (1/2) N/A
Prostate gland 2 No  (12/584)  (1/2) N/A
Skeletal muscle tissue 2 No N/A
Skin 2 No N/A
Small intestine 2 No  (9/584)  (2/2) N/A
Spinal cord 2 No  (2/2) N/A
Spleen 2 No  (2/584) N/A
Stomach 2 No  (12/584) N/A
Striatum 2 No  (1/2) N/A
Testis 2 No  (2/584)  (1/2) N/A
Thymus 2 No N/A
Thyroid gland 2 No  (15/584)  (1/2) N/A
Trachea 2 No  (1/2) N/A
Uterus 2 No  (1/2) N/A
White adipose tissue 2 No N/A
No Embryo expression data was found for this gene.

 Associated Images

Anti-nuclear antibody assay
6 Images
DSS Histology
8 Images
X-ray: XRay Images Lateral Orientation
32 Images
Sleep Wake: Wake state (bmp file)
6 Images
X-ray: XRay Images Forepaw
18 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
18 Images
Gross Morphology Embryo E9.5
6 Images
X-ray: XRay Images Dorso Ventral
46 Images
X-ray: XRay Images Skull Lateral Orientation
18 Images

 Disease Models

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 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Nadk2tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Nadk2tm1b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre) Mice
Nadk2em1(IMPC)J Intra-exdel deletion Mice

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