Gene: Chn1

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Name
chimerin 1
MGI ID
MGI:1915674
Synonyms
alpha1 chimaerin 0710001E19Rik 2900046J01Rik alpha2 chimaerin ARHGAP2 1700112L09Rik 0610007I19Rik
Embryo Screen
N/A
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
increased circulating alkaline phosphatase level Chn1tm1.1(KOMP)Vlcg HOM postnatal 8.72×10-07
increased erythrocyte cell number Chn1em1(IMPC)J HET postnatal 1.72×10-06
decreased circulating glucose level Chn1em1(IMPC)J HET postnatal 6.60×10-12
decreased bone mineral density Chn1em1(IMPC)J HET postnatal 1.47×10-06
abnormal behavior Chn1tm1.1(KOMP)Vlcg HOM postnatal 4.63×10-05
preweaning lethality, incomplete penetrance Chn1em1(IMPC)J HOM n/a 0.00
decreased total body fat amount Chn1tm1.1(KOMP)Vlcg HOM postnatal 1.04×10-11
increased hematocrit Chn1tm1.1(KOMP)Vlcg HOM postnatal 7.94×10-07
increased circulating sodium level Chn1tm1.1(KOMP)Vlcg HOM postnatal 7.23×10-05
decreased circulating iron level Chn1em1(IMPC)J HET postnatal 5.17×10-07
hypoactivity Chn1tm1.1(KOMP)Vlcg HOM postnatal 7.61×10-10
decreased circulating insulin level Chn1tm1.1(KOMP)Vlcg HOM postnatal 7.39×10-05
impaired righting response Chn1tm1.1(KOMP)Vlcg HOM postnatal 1.12×10-16
increased mean corpuscular hemoglobin Chn1tm1.1(KOMP)Vlcg HOM postnatal 8.52×10-10
decreased bone mineral content Chn1em1(IMPC)J HET postnatal 1.95×10-07
increased lean body mass Chn1tm1.1(KOMP)Vlcg HOM postnatal 8.80×10-08
increased circulating sodium level Chn1em1(IMPC)J HET postnatal 3.90×10-06
decreased circulating free fatty acid level Chn1tm1.1(KOMP)Vlcg HOM postnatal 2.29×10-09
decreased circulating glucose level Chn1tm1.1(KOMP)Vlcg HOM postnatal 1.60×10-06

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 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584)  (1/2) N/A
Aorta 2 No N/A
Bone 2 No  (2/2) N/A
Bone marrow 2 No  (2/2) N/A
Brain 2 No  (2/2) N/A
Brainstem 2 No  (2/2) N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No  (1/2) N/A
Cerebellum 2 No  (1/2) N/A
Cerebral cortex 2 No  (2/2) N/A
Epididymis 2 No  (18/134) N/A
Esophagus 2 No  (7/415)  (1/2) N/A
Eye 2 No  (1/2) N/A
Heart 2 No  (1/2) N/A
Hippocampus 2 No  (1/2) N/A
Hypothalamus 2 No  (1/2) N/A
Kidney 2 No  (18/584)  (2/2) N/A
Large intestine 2 No  (10/584)  (1/2) N/A
Liver 2 No N/A
Lower urinary tract 2 No N/A
Lung 2 No  (1/2) N/A
Lymph node 2 No N/A
Mammary gland 2 No N/A
Midbrain 2 No  (2/2) N/A
Olfactory lobe 2 No  (1/2) N/A
Ovary 2 No  (1/584)  (1/2) N/A
Oviduct 2 No  (1/2) N/A
Pancreas 2 No  (5/584)  (1/2) N/A
Peripheral nervous system 2 No N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No  (1/2) N/A
Prostate gland 2 No  (12/584) N/A
Skeletal muscle 2 No N/A
Skin 2 No  (1/2) N/A
Small intestine 2 No  (9/584)  (1/2) N/A
Spinal cord 2 No  (2/2) N/A
Spleen 2 No  (2/584)  (1/2) N/A
Stomach 2 No  (12/584)  (1/2) N/A
Striatum 2 No  (1/2) N/A
Submandibular gland 2 No  (2/132)  (1/2) N/A
Testis 2 No  (2/584)  (1/2) N/A
Thalamus 2 No  (1/2) N/A
Thymus 2 No  (1/2) N/A
Thyroid gland 2 No  (15/584)  (1/2) N/A
Trachea 2 No  (2/2) N/A
Urinary bladder 2 No N/A
Uterus 2 No  (1/2) N/A
Vascular system 2 No  (1/2) N/A
Vesicular gland 2 No N/A
White adipose tissue 2 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2  (6/485) N/A
Dorsal root ganglion 1  (1/47) N/A
Ear 2  (1/485) N/A
Embryo 2  (1/485)  (2/3)  Wholemount images
Eye 2  (1/485) N/A
Foot 2  (1/485)  (2/3) N/A
Forebrain 2  (1/485) N/A
Forelimb 2  (1/485)  (1/3) N/A
Fronto-nasal process 1  (1/48) N/A
Hand 2  (1/485)  (2/3) N/A
Head 2  (5/485)  (2/3) N/A
Heart 2  (1/485) N/A
Hindbrain 2  (6/485) N/A
Hindlimb 2  (1/485)  (1/3) N/A
Liver 2  (1/485) N/A
Lung 2  (1/485) N/A
Mandibular process 2  (1/485) N/A
Maxillary process 2  (1/485) N/A
Midbrain 2  (1/485) N/A
Nose 1  (1/51) N/A
Oral cavity 2  (1/485) N/A
Skin 2  (1/485) N/A
Spinal cord 1  (1/50) N/A
Tail 2  (1/485) N/A
Tail somite 2  (1/485) N/A

 Associated Images

Sleep Wake: Wake state (bmp file)
18 Images
X-ray: XRay Images Dorso Ventral
21 Images
X-ray: XRay Images Skull Lateral Orientation
21 Images
Combined SHIRPA and Dysmorphology
8 Images
X-ray: XRay Images Lateral Orientation
21 Images
X-ray: XRay Images Forepaw
21 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
21 Images
Embryo LacZ: LacZ images wholemount
12 Images

 Disease Models

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 Order Mouse and ES Cells

MGI Allele Allele Type Produced
Chn1tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Mice, Targeting vectors, ES Cells
Chn1tm1.1(KOMP)Vlcg Reporter-tagged deletion allele (post Cre, with no selection cassette) Mice
Chn1em1(IMPC)J Exon Deletion Mice

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