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Gene: Ndufs3

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Name
NADH:ubiquinone oxidoreductase core subunit S3
MGI ID
MGI:1915599
Synonyms
0610010M09Rik
Viability
No data available
Embryo viewer
N/A
Other links
MGI   Ensembl  
Significant phenotypes (11) Measurements chart (298) All data table (755)
Expression & images (45) Disease models (0) Histopathology (1) Order (2)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
decreased erythrocyte cell number Ndufs3tm1a(EUCOMM)Wtsi HET Early adult 1.74×10-09
decreased circulating LDL cholesterol level Ndufs3tm1a(EUCOMM)Wtsi HET Early adult 8.55×10-07
increased circulating phosphate level Ndufs3tm1a(EUCOMM)Wtsi HET Early adult 7.38×10-05
increased heart weight Ndufs3tm1a(EUCOMM)Wtsi HET Early adult 2.83×10-14
decreased circulating cholesterol level Ndufs3tm1a(EUCOMM)Wtsi HET Early adult 5.29×10-11
increased lean body mass Ndufs3tm1a(EUCOMM)Wtsi HET Early adult 1.60×10-06
decreased total body fat amount Ndufs3tm1a(EUCOMM)Wtsi HET Early adult 3.61×10-08
decreased circulating serum albumin level Ndufs3tm1a(EUCOMM)Wtsi HET Early adult 8.10×10-06
increased circulating calcium level Ndufs3tm1a(EUCOMM)Wtsi HET Early adult 5.74×10-05
increased bone mineral content Ndufs3tm1a(EUCOMM)Wtsi HET Early adult 1.96×10-06
decreased circulating alanine transaminase level Ndufs3tm1a(EUCOMM)Wtsi HET Early adult 2.33×10-05

Download data as:  TSV  XLS

Select physiological systems to view:
Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (4/583)  (2/2) N/A
Aorta 2 No  (1/583) N/A
Blood vessel 2 No  (2/2) N/A
Bone 2 No N/A
Brain 2 No  (4/583)  (2/2) N/A
Brainstem 2 No  (2/583) N/A
Brown adipose tissue 2 No  (2/2) N/A
Cartilage tissue 2 No  (1/583)  (2/2) N/A
Cerebellum 2 No  (3/583) N/A
Cerebral cortex 2 No  (2/583) N/A
Eye 2 No  (2/2) N/A
Gall bladder 2 No  (2/2) N/A
Heart 2 No  (2/583)  (2/2) N/A
Hippocampus 2 No  (3/583) N/A
Hypothalamus 2 No  (2/583) N/A
Kidney 2 No  (21/583)  (2/2) N/A
Large intestine 2 No  (10/583)  (2/2) N/A
Liver 2 No  (2/2) N/A
Lower urinary tract 2 No  (1/583)  (2/2) N/A
Lung 2 No  (2/583)  (2/2) N/A
Lymph node 2 No  (1/583)  (2/2) N/A
Mammary gland 2 No  (1/2) N/A
Esophagus 2 No  (2/2) N/A
Olfactory lobe 2 No  (2/583) N/A
Ovary 2 No  (1/583)  (1/2) N/A
Oviduct 2 No  (1/2) N/A
Pancreas 2 No  (5/583)  (2/2) N/A
Parathyroid gland 2 No  (1/563)  (2/2) N/A
Peripheral nervous system 2 No  (2/583)  (2/2) N/A
Peyer's patch 2 No  (1/176)  (2/2) N/A
Pituitary gland 2 No  (1/583)  (2/2) N/A
Prostate gland 2 No  (12/583)  (1/2) N/A
Skeletal muscle tissue 2 No  (2/2) N/A
Skin 2 No  (1/583)  (2/2) N/A
Small intestine 2 No  (9/583)  (2/2) N/A
Spinal cord 2 No  (3/583)  (2/2) N/A
Spleen 2 No  (3/583)  (2/2) N/A
Stomach 2 No  (13/583)  (2/2) N/A
Striatum 2 No  (3/583) N/A
Testis 2 No  (6/583)  (1/2) N/A
Thymus 2 No  (1/583)  (2/2) N/A
Thyroid gland 2 No  (17/583)  (2/2) N/A
Trachea 2 No  (3/583)  (2/2) N/A
Uterus 2 No  (1/2) N/A
White adipose tissue 2 No N/A
LacZ Wholemount Images
LacZ Section Images
LacZ Section Images
Ndufs3tm1a(EUCOMM)Wtsi
thymus, WT, Female, WTSI
Ndufs3tm1a(EUCOMM)Wtsi
heart, HET, Female, WTSI
Ndufs3tm1a(EUCOMM)Wtsi
blood vessel, HET, Female, WTSI
Ndufs3tm1a(EUCOMM)Wtsi
gall bladder, liver, HET, Female, WTSI
Ndufs3tm1a(EUCOMM)Wtsi
lung, HET, Female, WTSI

View all 30 images

Ndufs3tm1a(EUCOMM)Wtsi
thymus, WT, Female, WTSI
Ndufs3tm1a(EUCOMM)Wtsi
heart, HET, Female, WTSI
Ndufs3tm1a(EUCOMM)Wtsi
gall bladder, liver, HET, Female, WTSI
Ndufs3tm1a(EUCOMM)Wtsi
lung, HET, Female, WTSI
Ndufs3tm1a(EUCOMM)Wtsi
thymus, HET, Female, WTSI

View all 17 images

Ndufs3tm1a(EUCOMM)Wtsi
thymus, WT, Female, WTSI
Ndufs3tm1a(EUCOMM)Wtsi
thymus, HET, Female, WTSI
Ndufs3tm1a(EUCOMM)Wtsi
spleen, HET, Female, WTSI
Ndufs3tm1a(EUCOMM)Wtsi
peyer's patch, HET, Female, WTSI
Ndufs3tm1a(EUCOMM)Wtsi
lymph node, HET, Female, WTSI
Ndufs3tm1a(EUCOMM)Wtsi
gall bladder, liver, HET, Female, WTSI
Ndufs3tm1a(EUCOMM)Wtsi
large intestine, HET, Female, WTSI
Ndufs3tm1a(EUCOMM)Wtsi
peyer's patch, HET, Female, WTSI
Ndufs3tm1a(EUCOMM)Wtsi
oesophagus, HET, Female, WTSI
Ndufs3tm1a(EUCOMM)Wtsi
peripheral nervous system, pituitary gland, HET, Female, WTSI
Ndufs3tm1a(EUCOMM)Wtsi
brain, HET, Male, WTSI
Ndufs3tm1a(EUCOMM)Wtsi
brain, HET, Male, WTSI
Ndufs3tm1a(EUCOMM)Wtsi
spinal cord, HET, Female, WTSI
Ndufs3tm1a(EUCOMM)Wtsi
skin, HET, Female, WTSI
Ndufs3tm1a(EUCOMM)Wtsi
skin, HET, Female, WTSI
Ndufs3tm1a(EUCOMM)Wtsi
inguinal fat pad, mammary gland, white adipose tissue, HET, Female, WTSI
Ndufs3tm1a(EUCOMM)Wtsi
skeletal muscle tissue, cartilage tissue, bone, HET, Female, WTSI
Ndufs3tm1a(EUCOMM)Wtsi
inguinal fat pad, mammary gland, white adipose tissue, HET, Female, WTSI
Ndufs3tm1a(EUCOMM)Wtsi
brown adipose tissue, HET, Female, WTSI
Ndufs3tm1a(EUCOMM)Wtsi
urinary bladder, lower urinary tract, HET, Female, WTSI
Ndufs3tm1a(EUCOMM)Wtsi
kidney, HET, Male, WTSI
Ndufs3tm1a(EUCOMM)Wtsi
lower urinary tract, HET, Male, WTSI
Ndufs3tm1a(EUCOMM)Wtsi
inguinal fat pad, mammary gland, white adipose tissue, HET, Female, WTSI
Ndufs3tm1a(EUCOMM)Wtsi
brown adipose tissue, HET, Female, WTSI
Ndufs3tm1a(EUCOMM)Wtsi
heart, HET, Female, WTSI
Ndufs3tm1a(EUCOMM)Wtsi
blood vessel, HET, Female, WTSI
Ndufs3tm1a(EUCOMM)Wtsi
trachea, thyroid gland, parathyroid gland, HET, Female, WTSI
Ndufs3tm1a(EUCOMM)Wtsi
adrenal gland, HET, Male, WTSI
Ndufs3tm1a(EUCOMM)Wtsi
testis, HET, Male, WTSI
Ndufs3tm1a(EUCOMM)Wtsi
uterus, HET, Female, WTSI
Ndufs3tm1a(EUCOMM)Wtsi
lung, HET, Female, WTSI
Ndufs3tm1a(EUCOMM)Wtsi
trachea, thyroid gland, parathyroid gland, HET, Female, WTSI
Ndufs3tm1a(EUCOMM)Wtsi
inguinal fat pad, mammary gland, white adipose tissue, HET, Female, WTSI
Ndufs3tm1a(EUCOMM)Wtsi
skeletal muscle tissue, cartilage tissue, bone, HET, Female, WTSI
Ndufs3tm1a(EUCOMM)Wtsi
eye, HET, Female, WTSI
No Embryo expression data was found for this gene.

 Associated Images

Legacy Phenotype Associated Images
Ndufs3tm1a(EUCOMM)Wtsi
body, WT, Female, WTSI
Ndufs3tm1a(EUCOMM)Wtsi
head, WT, Female, WTSI
Ndufs3tm1a(EUCOMM)Wtsi
head, WT, Female, WTSI
Ndufs3tm1a(EUCOMM)Wtsi
head, WT, Female, WTSI
Ndufs3tm1a(EUCOMM)Wtsi
forearm, WT, Female, WTSI

View all 92 images

Ndufs3tm1a(EUCOMM)Wtsi
back skin, HET, Female, WTSI
Ndufs3tm1a(EUCOMM)Wtsi
back skin, HET, Female, WTSI
Ndufs3tm1a(EUCOMM)Wtsi
back skin, HET, Female, WTSI

 Disease Models

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 Histopathology

Phenotype Allele Zygosity Sex Life Stage
Heart - hypertrophy Ndufs3tm1a(EUCOMM)Wtsi HET Early adult

 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Ndufs3tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Targeting vectors, ES Cells
Ndufs3tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells

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