Stt3b | STT3, subunit of the oligosaccharyltransferase complex, homolog B (S. cerevisiae)

GeneMGI:1915542Synonyms: Simp, 1300006C19Rik

Physiological systems

18 / 24 physiological systems tested

6 Significantly impacted by the knock-out

 Homeostasis/metabolism Embryo Growth/size/body region Hematopoietic system Behavior/neurological Mortality/aging

12 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:9Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased locomotor activity1 supporting datasetStt3bem1(IMPC)JheterozygoteEarly adult2.17x10-7 
embryonic lethality prior to tooth bud stage1 supporting datasetStt3bem1(IMPC)JhomozygoteE12.5N/A * 
embryonic growth retardation1 supporting datasetStt3bem1(IMPC)JhomozygoteE9.5N/A * 
decreased exploration in new environment1 supporting datasetStt3bem1(IMPC)JheterozygoteEarly adult6.12x10-5 
decreased mean corpuscular hemoglobin1 supporting datasetStt3bem1(IMPC)JheterozygoteEarly adult4.82x10-9 
increased circulating cholesterol level1 supporting datasetStt3bem1(IMPC)JheterozygoteEarly adult5.06x10-5 
increased circulating alanine transaminase level1 supporting datasetStt3bem1(IMPC)JheterozygoteEarly adult3.56x10-6 
preweaning lethality, complete penetrance1 supporting datasetStt3bem1(IMPC)JhomozygoteEarly adultN/A * 
increased circulating bilirubin level1 supporting datasetStt3bem1(IMPC)JheterozygoteEarly adult4.33x10-12 
* Does not have a P-value assigned because it was manually marked as significant.
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* Does not have a P-value assigned because it was manually marked as significant.
Download data as:  

lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Stt3bem1(IMPC)JExon Deletionmouse
Stt3btm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
Stt3btm1e(EUCOMM)HmguTargeted, non-conditional allelees cell

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