Stt3b | STT3, subunit of the oligosaccharyltransferase complex, homolog B (S. cerevisiae)
Physiological systems
18 / 24 physiological systems tested
6 Significantly impacted by the knock-out
Homeostasis/metabolism Embryo Growth/size/body region Hematopoietic system Behavior/neurological Mortality/aging
12 No significant impact
6 Not tested
Data collections
Gene metrics:9Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
decreased locomotor activity | 1 supporting dataset | Stt3bem1(IMPC)J | heterozygote | Early adult | 2.17x10-7 | ||
embryonic lethality prior to tooth bud stage | 1 supporting dataset | Stt3bem1(IMPC)J | homozygote | E12.5 | N/A * | ||
embryonic growth retardation | 1 supporting dataset | Stt3bem1(IMPC)J | homozygote | E9.5 | N/A * | ||
decreased exploration in new environment | 1 supporting dataset | Stt3bem1(IMPC)J | heterozygote | Early adult | 6.12x10-5 | ||
decreased mean corpuscular hemoglobin | 1 supporting dataset | Stt3bem1(IMPC)J | heterozygote | Early adult | 4.82x10-9 | ||
increased circulating cholesterol level | 1 supporting dataset | Stt3bem1(IMPC)J | heterozygote | Early adult | 5.06x10-5 | ||
increased circulating alanine transaminase level | 1 supporting dataset | Stt3bem1(IMPC)J | heterozygote | Early adult | 3.56x10-6 | ||
preweaning lethality, complete penetrance | 1 supporting dataset | Stt3bem1(IMPC)J | homozygote | Early adult | N/A * | ||
increased circulating bilirubin level | 1 supporting dataset | Stt3bem1(IMPC)J | heterozygote | Early adult | 4.33x10-12 |
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External links
No external links available for Stt3b.
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Stt3bem1(IMPC)J | Exon Deletion | | mouse |
Stt3btm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector es cell |
Stt3btm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | es cell |