Dnaaf1 | dynein, axonemal assembly factor 1

GeneMGI:1915520Synonyms: 4930457P18Rik, Lrrc50, +1 more

Physiological systems

17 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Integument Mortality/aging Cardiovascular system

14 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:3Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal coat/ hair morphology1 supporting datasetDnaaf1em1(IMPC)JheterozygoteEarly adult1.51x10-6 
shortened PR interval1 supporting datasetDnaaf1em1(IMPC)JheterozygoteEarly adult7.3x10-5 
preweaning lethality, incomplete penetrance1 supporting datasetDnaaf1em1(IMPC)JhomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* Does not have a P-value assigned because it was manually marked as significant.
Download data as:  

lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Dnaaf1em1(IMPC)JExon Deletionmouse
Dnaaf1tm381102(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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