Sympk | symplekin

GeneMGI:1915438Synonyms: 4632415H16Rik, 1500016F02Rik

Physiological systems

20 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Homeostasis/metabolism Behavior/neurological Mortality/aging

17 No significant impact

4 Not tested

Data collections

Viability data
Body weight measurements
Embryo imaging data
Gene metrics:3Significant phenotypes
0Associated diseases
Expression examined in:45Adult tissues
0Embryo tissues

Phenotypes

increased circulating chloride level1 supporting datasetSympktm1a(EUCOMM)WtsiheterozygoteEarly adult1.65x10-5 
abnormal behavior3 supporting datasetsSympktm1a(EUCOMM)WtsiheterozygoteEarly adult2.94x10-5 
preweaning lethality, complete penetrance1 supporting datasetSympktm1a(EUCOMM)WtsihomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Sympktm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse

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