Gene: Ino80

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INO80 complex subunit
2310079N15Rik INO80 4632409L19Rik Inoc1
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Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
increased cardiac muscle contractility Ino80tm1a(EUCOMM)Hmgu HET Early adult 3.63×10-05
decreased grip strength Ino80tm1a(EUCOMM)Hmgu HET Early adult 4.20×10-05
prolonged QRS complex duration Ino80tm1a(EUCOMM)Hmgu HET Early adult 7.74×10-05
hypoactivity Ino80tm1a(EUCOMM)Hmgu HET Early adult 2.96×10-13
preweaning lethality, incomplete penetrance Ino80tm1b(EUCOMM)Hmgu HOM   Early adult 0.00
decreased heart rate Ino80tm1a(EUCOMM)Hmgu HET Early adult 2.44×10-07
decreased exploration in new environment Ino80tm1a(EUCOMM)Hmgu HET Early adult 3.47×10-08
abnormal vocalization Ino80tm1a(EUCOMM)Hmgu HET Early adult 1.60×10-05
abnormal seminal vesicle morphology Ino80tm1a(EUCOMM)Hmgu HET Early adult 0.00
prolonged RR interval Ino80tm1a(EUCOMM)Hmgu HET Early adult 2.08×10-06
preweaning lethality, complete penetrance Ino80tm1a(EUCOMM)Hmgu HOM   Early adult 0.00
decreased blood urea nitrogen level Ino80tm1b(EUCOMM)Hmgu HET Early adult 5.98×10-06
increased aggression Ino80tm1a(EUCOMM)Hmgu HET   Early adult 3.99×10-06

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Viewing: all phenotypes


IMPC lacZ Expression Data

No Adult expression data was found for this gene.
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2  (6/507)  (2/3) N/A
Ear 2  (1/507)  (2/3) N/A
Embryo 2  (1/508)  (2/3) N/A
Eye 2  (1/507)  (2/3) N/A
Footplate 2  (1/507) N/A
Forebrain 2  (1/507)  (2/3) N/A
Forelimb 2  (1/507)  (2/3) N/A
Handplate 2  (1/507) N/A
Head 2  (5/507)  (2/3) N/A
Heart 2  (1/507)  (2/3) N/A
Hindbrain 2  (6/507)  (2/3) N/A
Hindlimb 2  (1/507)  (2/3) N/A
Liver 2  (1/502)  (2/3) N/A
Lung 2  (1/502)  (2/3) N/A
Mandibular process 2  (1/507)  (2/3) N/A
Maxillary process 2  (1/507)  (2/3) N/A
Midbrain 2  (1/507)  (2/3) N/A
Oral cavity 2  (1/502)  (2/3) N/A
Placenta 1  (7/42)  (2/2) N/A
Skin 2  (1/507)  (2/3) N/A
Tail 2  (1/507)  (2/3) N/A
Tail somite group 2  (1/507)  (2/3) N/A

 Associated Images

Echo: M-Mode Images
14 Images
X-ray: XRay Images Whole Body Dorso Ventral
20 Images
X-ray: XRay Images Whole Body Lateral Orientation
10 Images
Embryo LacZ: LacZ images wholemount
2 Images
Gross Pathology and Tissue Collection
1 Images
Embryo LacZ: LacZ images section
1 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Ino80tm1b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre) Mice
Ino80tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells

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