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Genes Phenotypes

Gene: Ino80

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Name
INO80 complex subunit
MGI ID
MGI:1915392
Synonyms
2310079N15Rik 4632409L19Rik INO80 Inoc1
Viability
Homozygous - Lethal Homozygous - Subviable
Embryo viewer
3D Imaging
Other links
MGI   Ensembl  
Significant phenotypes (8) Measurements chart (192) All data table (736)
Expression & images (22) Disease models (0) Order (2)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
abnormal seminal vesicle morphology Ino80tm1a(EUCOMM)Hmgu HET Early adult 0.00
increased cardiac muscle contractility Ino80tm1a(EUCOMM)Hmgu HET Early adult 3.63×10-05
hypoactivity Ino80tm1a(EUCOMM)Hmgu HET Early adult 1.05×10-13
decreased exploration in new environment Ino80tm1a(EUCOMM)Hmgu HET Early adult 4.88×10-08
increased aggression Ino80tm1a(EUCOMM)Hmgu HET   Early adult 3.35×10-05
preweaning lethality, incomplete penetrance Ino80tm1b(EUCOMM)Hmgu HOM   Early adult 0.00
decreased grip strength Ino80tm1a(EUCOMM)Hmgu HET Early adult 4.20×10-05
preweaning lethality, complete penetrance Ino80tm1a(EUCOMM)Hmgu HOM   Early adult 0.00

Download data as:  TSV  XLS

Select physiological systems to view:
Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

No Adult expression data was found for this gene.
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2  (6/506)  (2/3) N/A
Ear 2  (1/506)  (2/3) N/A
Embryo 2  (1/507)  (2/3) N/A
Eye 2  (1/506)  (2/3) N/A
Foot 2  (1/506) N/A
Forebrain 2  (1/506)  (2/3) N/A
Forelimb 2  (1/506)  (2/3) N/A
Hand 2  (1/506) N/A
Head 2  (5/506)  (2/3) N/A
Heart 2  (1/506)  (2/3) N/A
Hindbrain 2  (6/506)  (2/3) N/A
Hindlimb 2  (1/506)  (2/3) N/A
Liver 2  (1/504)  (2/3) N/A
Lung 2  (1/504)  (2/3) N/A
Mandibular process 2  (1/506)  (2/3) N/A
Maxillary process 2  (1/506)  (2/3) N/A
Midbrain 2  (1/506)  (2/3) N/A
Oral cavity 2  (1/504)  (2/3) N/A
Chorioallantoic placenta 1  (7/39)  (2/2) N/A
Skin 2  (1/506)  (2/3) N/A
Tail 2  (1/506)  (2/3) N/A
Tail somite 2  (1/506)  (2/3) N/A

 Associated Images

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X-ray: XRay Images Whole Body Dorso Ventral
20 Images
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X-ray: XRay Images Whole Body Lateral Orientation
10 Images
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Echo: M-Mode Images
14 Images
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Embryo LacZ: LacZ images wholemount
2 Images
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Gross Pathology and Tissue Collection
1 Images
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Embryo LacZ: LacZ images section
1 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Ino80tm1b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre) Mice
Ino80tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells

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