Gene: Retreg3

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Name
reticulophagy regulator family member 3
MGI ID
MGI:1915248
Synonyms
1300010M03Rik Fam134c 4933404C01Rik
Embryo viewer
N/A
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
decreased bone mineral content Retreg3tm2b(EUCOMM)Wtsi HOM Early adult 6.21×10-08
increased red blood cell distribution width Retreg3tm2b(EUCOMM)Wtsi HOM Early adult 6.27×10-05
abnormal retina morphology Retreg3tm2a(EUCOMM)Wtsi HOM Early adult 5.34×10-06
abnormal eye morphology Retreg3tm2a(EUCOMM)Wtsi HOM Early adult 9.43×10-06
decreased body weight Retreg3tm2a(EUCOMM)Wtsi HOM Early adult 1.70×10-05
decreased prepulse inhibition Retreg3tm2b(EUCOMM)Wtsi HOM Early adult 4.09×10-09
decreased total body fat amount Retreg3tm2b(EUCOMM)Wtsi HOM Early adult 3.01×10-08
abnormal retinal pigmentation Retreg3tm2a(EUCOMM)Wtsi HOM Early adult 5.34×10-06
increased circulating amylase level Retreg3tm2b(EUCOMM)Wtsi HOM Early adult 3.96×10-08
increased blood urea nitrogen level Retreg3tm2b(EUCOMM)Wtsi HOM Early adult 6.99×10-05
abnormal bone structure Retreg3tm2b(EUCOMM)Wtsi HOM Early adult 1.40×10-07
increased lean body mass Retreg3tm2b(EUCOMM)Wtsi HOM Early adult 4.43×10-07
decreased circulating glucose level Retreg3tm2b(EUCOMM)Wtsi HOM Early adult 7.94×10-06
decreased hemoglobin content Retreg3tm2a(EUCOMM)Wtsi HOM Early adult 5.93×10-05

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 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 4 No  (2/584) N/A
Aorta 4 No N/A
Blood vessel 2 No N/A
Bone 4 No N/A
Brain 4 No N/A
Brainstem 4 No N/A
Brown adipose tissue 4 No N/A
Cartilage tissue 4 No N/A
Cerebellum 4 No N/A
Cerebral cortex 4 No N/A
Esophagus 2 No  (7/415) N/A
Eye 4 No N/A
Gall bladder 4 No N/A
Heart 4 No N/A
Hippocampus 4 No N/A
Hypothalamus 4 No N/A
Kidney 4 No  (18/584) N/A
Large intestine 4 No  (10/584) N/A
Liver 4 No N/A
Lower urinary tract 4 No N/A
Lung 4 No N/A
Lymph node 4 No N/A
Mammary gland 4 No N/A
Esophagus 2 No N/A
Olfactory lobe 4 No N/A
Oral epithelium 2 No N/A
Ovary 4 No  (1/584) N/A
Oviduct 4 No N/A
Pancreas 4 No  (5/584) N/A
Parathyroid gland 4 No N/A
Peripheral nervous system 4 No N/A
Peyer's patch 2 No N/A
Peyer's patch 2 No N/A
Pituitary gland 4 No N/A
Prostate gland 4 No  (12/584) N/A
Skeletal muscle 2 No N/A
Skeletal muscle tissue 2 No N/A
Skin 4 No N/A
Small intestine 4 No  (9/584) N/A
Spinal cord 4 No N/A
Spleen 4 No  (2/584) N/A
Stomach 4 No  (12/584) N/A
Striatum 4 No N/A
Testis 4 No  (2/584) N/A
Thymus 4 No N/A
Thyroid gland 4 No  (15/584) N/A
Trachea 4 No N/A
Uterus 4 No N/A
Vascular system 2 No N/A
White adipose tissue 4 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 1  (6/504) N/A
Ear 1  (1/504) N/A
Embryo 1  (1/505) N/A
Eye 1  (1/504) N/A
Foot 1  (1/504) N/A
Forebrain 1  (1/504) N/A
Forelimb 1  (1/504) N/A
Hand 1  (1/503) N/A
Head 1  (5/504) N/A
Heart 1  (1/504) N/A
Hindbrain 1  (6/504) N/A
Hindlimb 1  (1/503) N/A
Liver 1  (1/504) N/A
Lung 1  (1/500) N/A
Mandibular process 1  (1/504) N/A
Maxillary process 1  (1/504) N/A
Midbrain 1  (1/504) N/A
Oral cavity 1  (1/504) N/A
Skin 1  (1/504) N/A
Tail 1  (1/504) N/A
Tail somite 1  (1/504) N/A

 Associated Images

X-ray: XRay Images Whole Body Dorso Ventral
10 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
10 Images
X-ray: XRay Images Whole Body Lateral Orientation
10 Images
Echo: M-Mode Images
64 Images
Auditory Brain Stem Response: Click-evoked + 6 to 30kHz tone waveforms (pdf format)
4 Images
Embryo LacZ: LacZ images wholemount
8 Images
X-ray: XRay Images Skull Lateral Orientation
2 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Retreg3tm2a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Retreg3tm2b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre) Mice
Retreg3tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells
Retreg3tm3a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells
Retreg3tm95(pL1L2_GT2_DelLacZ_bsd) Targeting vectors

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