Srsf6 | serine and arginine-rich splicing factor 6

GeneMGI:1915246Synonyms: Sfrs6, 1210001E11Rik

Physiological systems

20 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Embryo Growth/size/body region Behavior/neurological Mortality/aging

16 No significant impact

4 Not tested

Gene metrics:4Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

preweaning lethality, incomplete penetrance1 supporting datasetSrsf6em1(IMPC)JhomozygoteEarly adultN/A * 
increased grip strength1 supporting datasetSrsf6em1(IMPC)JheterozygoteEarly adult8.6x10-5 
abnormal embryo size1 supporting datasetSrsf6em1(IMPC)JhomozygoteE18.5N/A * 
abnormal vocalization1 supporting datasetSrsf6em1(IMPC)JheterozygoteEarly adult1.46x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* Does not have a P-value assigned because it was manually marked as significant.
Download data as:  

lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Srsf6em1(IMPC)JExon Deletionmouse
Srsf6tm1(KOMP)WtsiReporter-tagged deletion allele (with selection cassette)targeting vector
es cell
Srsf6tm437563(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector
Srsf6tm437563(L1L2_GT1_LF2A_LacZ_BetactP_neo)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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