Gene: Gnpda2

Name
glucosamine-6-phosphate deaminase 2
MGI ID
MGI:1915230
Synonyms
4921523I18Rik 4933412A11Rik Gnp2
Viability
Homozygous - Viable
Other links
Significant phenotypes (0) All measurements (195) Expression & images (73) Disease models (0) Order (4)
View data by physiological system
Significant
Not Significant
Not tested

Filtered by: all phenotypes

Mouseover the data points for more information. Click and drag to zoom the chart. Click on the legends to disable/enable data.

Allele Center Procedure / Parameter Zygosity Mutants Statistical
Method
P Value Status
Gnpda2tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Tail - thickness HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Gnpda2tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Forelimb digit - size HOM 8f:7m Fisher Exact Test framework 1.00 Success
Gnpda2tm1.1(KOMP)Vlcg UC Davis Clinical Chemistry / Alanine aminotransferase HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.352 Success
Gnpda2tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Coat - hair distribution - back HOM 8f:7m Fisher Exact Test framework 1.00 Success
Gnpda2tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Forelimb nail - shape HOM 8f:7m Fisher Exact Test framework 1.00 Success
Gnpda2tm1.1(KOMP)Vlcg UC Davis Hematology / Monocyte differential count HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.139 Success
Gnpda2tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Head bobbing HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Gnpda2tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Skin texture - whole body HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Gnpda2tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Trunk curl HOM 8f:7m Fisher Exact Test framework 1.00 Success
Gnpda2tm1.1(KOMP)Vlcg UC Davis Clinical Chemistry / Creatinine HOM 6f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0119 Success
Gnpda2tm1.1(KOMP)Vlcg UC Davis Body Composition (DEXA lean/fat) / Lean/Body weight HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0514 Success
Gnpda2tm1.1(KOMP)Vlcg UC Davis X-ray / Number of thoracic vertebrae HOM 5f:5m Not processed 1.00 FAILED - No variability in dependent variable 'IMPC_XRY_014_001'.
Gnpda2tm1.1(KOMP)Vlcg UC Davis X-ray / Number of ribs right HOM 5f:5m Not processed 1.00 FAILED - No variability in dependent variable 'IMPC_XRY_008_001'.
Gnpda2tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Skin texture - ear HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Gnpda2tm1.1(KOMP)Vlcg UC Davis Hematology / Mean cell hemoglobin concentration HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.381 Success
Gnpda2tm1.1(KOMP)Vlcg UC Davis Open Field / Distance travelled - total HOM 0f:5m Mixed Model framework, generalized least squares, equation withoutWeight 0.00400 Success
Gnpda2tm1.1(KOMP)Vlcg UC Davis Open Field / Distance travelled - total HOM 8f:2m Not processed 1.00 FAILED - Not enough data points in dependent variable 'IMPC_OFD_020_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Gnpda2tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Snout size HOM 8f:7m Fisher Exact Test framework 0.0724 Success
Gnpda2tm1.1(KOMP)Vlcg UC Davis Auditory Brain Stem Response / Click-evoked ABR threshold HOM 2f:2m 0.616 Success
Gnpda2tm1.1(KOMP)Vlcg UC Davis Auditory Brain Stem Response / 24kHz-evoked ABR Threshold HOM 2f:2m 1.00 Success
Gnpda2tm1.1(KOMP)Vlcg UC Davis Clinical Chemistry / Total cholesterol HOM 6f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.962 Success
Gnpda2tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Genitalia - size HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Gnpda2tm1.1(KOMP)Vlcg UC Davis Open Field / Periphery permanence time HOM 0f:5m Mixed Model framework, generalized least squares, equation withWeight 0.997 Success
Gnpda2tm1.1(KOMP)Vlcg UC Davis Open Field / Periphery permanence time HOM 8f:2m Not processed 1.00 FAILED - Not enough data points in dependent variable 'IMPC_OFD_012_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Gnpda2tm1.1(KOMP)Vlcg UC Davis X-ray / Radius HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Gnpda2tm1.1(KOMP)Vlcg UC Davis Clinical Chemistry / Albumin HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.316 Success
Gnpda2tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Forelimb nail - length HOM 8f:7m Fisher Exact Test framework 1.00 Success
Gnpda2tm1.1(KOMP)Vlcg UC Davis Intraperitoneal glucose tolerance test (IPGTT) / Initial response to glucose challenge HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.142 Success
Gnpda2tm1.1(KOMP)Vlcg UC Davis X-ray / Fibula HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Gnpda2tm1.1(KOMP)Vlcg UC Davis Hematology / Eosinophil differential count HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.00222 Success
Gnpda2tm1.1(KOMP)Vlcg UC Davis Hematology / Mean platelet volume HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.283 Success
Gnpda2tm1.1(KOMP)Vlcg UC Davis Open Field / Percentage center time HOM 0f:5m Mixed Model framework, generalized least squares, equation withWeight 0.997 Success
Gnpda2tm1.1(KOMP)Vlcg UC Davis Open Field / Percentage center time HOM 8f:2m Not processed 1.00 FAILED - Not enough data points in dependent variable 'IMPC_OFD_022_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Gnpda2tm1.1(KOMP)Vlcg UC Davis Auditory Brain Stem Response / 6kHz-evoked ABR Threshold HOM 2f:2m 1.00 Success
Gnpda2tm1.1(KOMP)Vlcg UC Davis X-ray / Shape of vertebrae HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Gnpda2tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Aggression HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Gnpda2tm1.1(KOMP)Vlcg UC Davis Body Composition (DEXA lean/fat) / Body length HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0108 Success
Gnpda2tm1.1(KOMP)Vlcg UC Davis X-ray / Brachydactyly HOM 5f:5m Fisher Exact Test framework 1.00 Success
Gnpda2tm1.1(KOMP)Vlcg UC Davis X-ray / Pelvis HOM 5f:5m Fisher Exact Test framework 1.00 Success
Gnpda2tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Vibrissae - presence HOM 8f:7m Fisher Exact Test framework 1.00 Success
Gnpda2tm1.1(KOMP)Vlcg UC Davis Grip Strength / Forelimb grip strength measurement mean HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.993 Success
Gnpda2tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Startle response HOM 8f:7m Fisher Exact Test framework 1.00 Success
Gnpda2tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Hindlimbs - shape HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Gnpda2tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Lower teeth appearance HOM 8f:7m Fisher Exact Test framework 1.00 Success
Gnpda2tm1.1(KOMP)Vlcg UC Davis X-ray / Scapulae HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Gnpda2tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Skin texture - back paws HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Gnpda2tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Forelimbs - shape HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Gnpda2tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Forelimb digit - shape HOM 8f:7m Fisher Exact Test framework 1.00 Success
Gnpda2tm1.1(KOMP)Vlcg UC Davis Hematology / Mean cell volume HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.239 Success
Gnpda2tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Coat - color - back HOM 8f:7m Fisher Exact Test framework 1.00 Success
Gnpda2tm1.1(KOMP)Vlcg UC Davis Open Field / Periphery distance travelled HOM 0f:5m Mixed Model framework, generalized least squares, equation withoutWeight 0.000149 Success
Gnpda2tm1.1(KOMP)Vlcg UC Davis Open Field / Periphery distance travelled HOM 8f:2m Not processed 1.00 FAILED - Not enough data points in dependent variable 'IMPC_OFD_010_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Gnpda2tm1.1(KOMP)Vlcg UC Davis X-ray / Femur HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Gnpda2tm1.1(KOMP)Vlcg UC Davis Open Field / Center permanence time HOM 0f:5m Mixed Model framework, generalized least squares, equation withWeight 0.997 Success
Gnpda2tm1.1(KOMP)Vlcg UC Davis Open Field / Center permanence time HOM 8f:2m Not processed 1.00 FAILED - Not enough data points in dependent variable 'IMPC_OFD_016_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Gnpda2tm1.1(KOMP)Vlcg UC Davis Auditory Brain Stem Response / 12kHz-evoked ABR Threshold HOM 2f:2m 1.00 Success
Gnpda2tm1.1(KOMP)Vlcg UC Davis X-ray / Zygomatic bone HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Gnpda2tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Hindpaw - size HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Gnpda2tm1.1(KOMP)Vlcg UC Davis Hematology / Basophil cell count HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0241 Success
Gnpda2tm1.1(KOMP)Vlcg UC Davis Clinical Chemistry / Calcium HOM 6f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.918 Success
Gnpda2tm1.1(KOMP)Vlcg UC Davis Body Composition (DEXA lean/fat) / Bone Mineral Density (excluding skull) HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0479 Success
Gnpda2tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Upper lip morphology HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Gnpda2tm1.1(KOMP)Vlcg UC Davis Hematology / Red blood cell count HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0441 Success
Gnpda2tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Locomotor activity HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.449 Success
Gnpda2tm1.1(KOMP)Vlcg UC Davis X-ray / Shape of ribs HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Gnpda2tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Contact righting HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Gnpda2tm1.1(KOMP)Vlcg UC Davis Hematology / Hematocrit HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.531 Success
Gnpda2tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Hindlimb nail - number HOM 8f:7m Fisher Exact Test framework 1.00 Success
Gnpda2tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Skin color - ear HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Gnpda2tm1.1(KOMP)Vlcg UC Davis Grip Strength / Forelimb and hindlimb grip strength normalised against body weight HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.520 Success
Gnpda2tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Coat - hair texture / appearance - head HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Gnpda2tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Skin texture - tail HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Gnpda2tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Vibrissae - appearance HOM 8f:7m Fisher Exact Test framework 1.00 Success
Gnpda2tm1.1(KOMP)Vlcg UC Davis Intraperitoneal glucose tolerance test (IPGTT) / Area under glucose response curve HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.458 Success
Gnpda2tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Coat - color - abdomen HOM 8f:7m Fisher Exact Test framework 1.00 Success
Gnpda2tm1.1(KOMP)Vlcg UC Davis Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI1 HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.434 Success
Gnpda2tm1.1(KOMP)Vlcg UC Davis Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI3 HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0209 Success
Gnpda2tm1.1(KOMP)Vlcg UC Davis Body Composition (DEXA lean/fat) / Fat mass HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.128 Success
Gnpda2tm1.1(KOMP)Vlcg UC Davis Auditory Brain Stem Response / 30kHz-evoked ABR Threshold HOM 2f:2m 1.00 Success
Gnpda2tm1.1(KOMP)Vlcg UC Davis Clinical Chemistry / Phosphorus HOM 6f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.732 Success
Gnpda2tm1.1(KOMP)Vlcg UC Davis X-ray / Mandibles HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Gnpda2tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Hindpaw - shape HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Gnpda2tm1.1(KOMP)Vlcg UC Davis Hematology / Neutrophil cell count HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.925 Success
Gnpda2tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Tremor HOM 8f:7m Fisher Exact Test framework 1.00 Success
Gnpda2tm1.1(KOMP)Vlcg UC Davis Viability Primary Screen / Outcome HOM 67f:68m Supplied as data Success
Gnpda2tm1.1(KOMP)Vlcg UC Davis X-ray / Humerus HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Gnpda2tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Genitalia - morphology HOM 8f:7m Fisher Exact Test framework 1.00 Success
Gnpda2tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Skin color - back paws HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Gnpda2tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Limb grasp HOM 8f:7m Fisher Exact Test framework 0.0290 Success
Gnpda2tm1.1(KOMP)Vlcg UC Davis Hematology / Lymphocyte cell count HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.224 Success
Gnpda2tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Head morphology HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Gnpda2tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Skin color - whole body HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Gnpda2tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Upper teeth appearance HOM 8f:7m Fisher Exact Test framework 1.00 Success
Gnpda2tm1.1(KOMP)Vlcg UC Davis Open Field / Center distance travelled HOM 0f:5m Mixed Model framework, generalized least squares, equation withWeight 0.604 Success
Gnpda2tm1.1(KOMP)Vlcg UC Davis Open Field / Center distance travelled HOM 8f:2m Not processed 1.00 FAILED - Not enough data points in dependent variable 'IMPC_OFD_014_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Gnpda2tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Coat - hair distribution - abdomen HOM 8f:7m Fisher Exact Test framework 0.0936 Success
Gnpda2tm1.1(KOMP)Vlcg UC Davis Auditory Brain Stem Response / 18kHz-evoked ABR Threshold HOM 2f:2m 1.00 Success
Gnpda2tm1.1(KOMP)Vlcg UC Davis X-ray / Number of digits HOM 5f:5m Not processed 1.00 FAILED - No variability in dependent variable 'IMPC_XRY_028_001'.
Gnpda2tm1.1(KOMP)Vlcg UC Davis Clinical Chemistry / Triglycerides HOM 6f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.266 Success
Gnpda2tm1.1(KOMP)Vlcg UC Davis Clinical Chemistry / Urea (Blood Urea Nitrogen - BUN) HOM 6f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.000308 Success
Gnpda2tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Coat - color pattern - head HOM 8f:7m Fisher Exact Test framework 1.00 Success
Gnpda2tm1.1(KOMP)Vlcg UC Davis X-ray / Clavicle HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Gnpda2tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Genitalia - presence HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Gnpda2tm1.1(KOMP)Vlcg UC Davis X-ray / Number of lumbar vertebrae HOM 5f:5m Not processed 1.00 FAILED - No variability in dependent variable 'IMPC_XRY_015_001'.
Gnpda2tm1.1(KOMP)Vlcg UC Davis Hematology / Platelet count HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.918 Success
Gnpda2tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Activity (body position) HOM 8f:7m Fisher Exact Test framework 1.00 Success
Gnpda2tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Hindlimb nail - shape HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Gnpda2tm1.1(KOMP)Vlcg UC Davis X-ray / Ulna HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Gnpda2tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Coat - hair distribution - head HOM 8f:7m Fisher Exact Test framework 1.00 Success
Gnpda2tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Hindlimb digit - size HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Gnpda2tm1.1(KOMP)Vlcg UC Davis Clinical Chemistry / Alkaline phosphatase HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.000721 Success
Gnpda2tm1.1(KOMP)Vlcg UC Davis X-ray / Digit integrity HOM 5f:5m Fisher Exact Test framework 1.00 Success
Gnpda2tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Hindlimb digit - number HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Gnpda2tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Tail - length HOM 8f:7m Fisher Exact Test framework 1.00 Success
Gnpda2tm1.1(KOMP)Vlcg UC Davis Hematology / Monocyte cell count HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.821 Success
Gnpda2tm1.1(KOMP)Vlcg UC Davis Open Field / Number of rears - total HOM 0f:5m Mixed Model framework, generalized least squares, equation withoutWeight 0.255 Success
Gnpda2tm1.1(KOMP)Vlcg UC Davis Open Field / Number of rears - total HOM 8f:2m Not processed 1.00 FAILED - Not enough data points in dependent variable 'IMPC_OFD_021_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Gnpda2tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Unexpected behaviors HOM 8f:7m Fisher Exact Test framework 1.00 Success
Gnpda2tm1.1(KOMP)Vlcg UC Davis X-ray / Teeth HOM 5f:5m Fisher Exact Test framework 1.00 Success
Gnpda2tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Skin texture - snout HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Gnpda2tm1.1(KOMP)Vlcg UC Davis Clinical Chemistry / Total protein HOM 6f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.735 Success
Gnpda2tm1.1(KOMP)Vlcg UC Davis X-ray / Number of ribs left HOM 5f:5m Not processed 1.00 FAILED - No variability in dependent variable 'IMPC_XRY_009_001'.
Gnpda2tm1.1(KOMP)Vlcg UC Davis Body Composition (DEXA lean/fat) / Fat/Body weight HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0869 Success
Gnpda2tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Hindlimbs - position HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Gnpda2tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Hindlimbs - size HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Gnpda2tm1.1(KOMP)Vlcg UC Davis X-ray / Number of cervical vertebrae HOM 5f:5m Not processed 1.00 FAILED - No variability in dependent variable 'IMPC_XRY_013_001'.
Gnpda2tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Skin texture - front paws HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Gnpda2tm1.1(KOMP)Vlcg UC Davis Body Composition (DEXA lean/fat) / Bone Area HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.250 Success
Gnpda2tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Coat - color - head HOM 8f:7m Fisher Exact Test framework 1.00 Success
Gnpda2tm1.1(KOMP)Vlcg UC Davis Hematology / Mean corpuscular hemoglobin HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.191 Success
Gnpda2tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Forelimbs - size HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Gnpda2tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Hindlimb digit - shape HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Gnpda2tm1.1(KOMP)Vlcg UC Davis X-ray / Fusion of vertebrae HOM 5f:5m Fisher Exact Test framework 0.161 Success
Gnpda2tm1.1(KOMP)Vlcg UC Davis Intraperitoneal glucose tolerance test (IPGTT) / Fasted blood glucose concentration HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.230 Success
Gnpda2tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Forepaw - size HOM 8f:7m Fisher Exact Test framework 1.00 Success
Gnpda2tm1.1(KOMP)Vlcg UC Davis X-ray / Tibia HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Gnpda2tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Tail - morphology HOM 8f:7m Fisher Exact Test framework 1.00 Success
Gnpda2tm1.1(KOMP)Vlcg UC Davis Clinical Chemistry / Total bilirubin HOM 6f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.00413 Success
Gnpda2tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Coat - color pattern - abdomen HOM 8f:7m Fisher Exact Test framework 1.00 Success
Gnpda2tm1.1(KOMP)Vlcg UC Davis Clinical Chemistry / Aspartate aminotransferase HOM 6f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.329 Success
Gnpda2tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Forelimbs - position HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Gnpda2tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Hindlimb nail - length HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Gnpda2tm1.1(KOMP)Vlcg UC Davis X-ray / Fusion of ribs HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Gnpda2tm1.1(KOMP)Vlcg UC Davis Hematology / Eosinophil cell count HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0328 Success
Gnpda2tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Vocalization HOM 8f:7m Fisher Exact Test framework 0.261 Success
Gnpda2tm1.1(KOMP)Vlcg UC Davis Body Composition (DEXA lean/fat) / BMC/Body weight HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.976 Success
Gnpda2tm1.1(KOMP)Vlcg UC Davis Grip Strength / Forelimb and hindlimb grip strength measurement mean HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.711 Success
Gnpda2tm1.1(KOMP)Vlcg UC Davis Hematology / Hemoglobin HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.753 Success
Gnpda2tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Lower lip morphology HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Gnpda2tm1.1(KOMP)Vlcg UC Davis Hematology / Basophil differential count HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.000154 Success
Gnpda2tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Skin color - front paws HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Gnpda2tm1.1(KOMP)Vlcg UC Davis Open Field / Whole arena resting time HOM 0f:5m Mixed Model framework, generalized least squares, equation withoutWeight 0.000242 Success
Gnpda2tm1.1(KOMP)Vlcg UC Davis Open Field / Whole arena resting time HOM 8f:2m Not processed 1.00 FAILED - Not enough data points in dependent variable 'IMPC_OFD_007_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Gnpda2tm1.1(KOMP)Vlcg UC Davis X-ray / Syndactylism HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Gnpda2tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Coat - hair texture / appearance - abdomen HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Gnpda2tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Teeth presence HOM 8f:7m Fisher Exact Test framework 1.00 Success
Gnpda2tm1.1(KOMP)Vlcg UC Davis Grip Strength / Forelimb grip strength normalised against body weight HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.110 Success
Gnpda2tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Head size HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Gnpda2tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Coat - color pattern - back HOM 8f:7m Fisher Exact Test framework 1.00 Success
Gnpda2tm1.1(KOMP)Vlcg UC Davis Clinical Chemistry / Glucose HOM 6f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.682 Success
Gnpda2tm1.1(KOMP)Vlcg UC Davis Open Field / Center average speed HOM 0f:5m Mixed Model framework, generalized least squares, equation withoutWeight 0.776 Success
Gnpda2tm1.1(KOMP)Vlcg UC Davis Open Field / Center average speed HOM 8f:2m Not processed 1.00 FAILED - Not enough data points in dependent variable 'IMPC_OFD_017_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Gnpda2tm1.1(KOMP)Vlcg UC Davis Fertility of Homozygous Knock-out Mice / Gross Findings Female HOM f:m Supplied as data Success
Gnpda2tm1.1(KOMP)Vlcg UC Davis X-ray / Joints HOM 5f:5m Fisher Exact Test framework 1.00 Success
Gnpda2tm1.1(KOMP)Vlcg UC Davis Heart Weight / Heart weight HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.176 Success
Gnpda2tm1.1(KOMP)Vlcg UC Davis X-ray / Skull shape HOM 5f:5m Fisher Exact Test framework 1.00 Success
Gnpda2tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Forepaw - shape HOM 8f:7m Fisher Exact Test framework 1.00 Success
Gnpda2tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Forelimb nail - number HOM 8f:7m Fisher Exact Test framework 1.00 Success
Gnpda2tm1.1(KOMP)Vlcg UC Davis Body Composition (DEXA lean/fat) / Bone Mineral Content (excluding skull) HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.00402 Success
Gnpda2tm1.1(KOMP)Vlcg UC Davis Hematology / Neutrophil differential count HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.186 Success
Gnpda2tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Gait HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Gnpda2tm1.1(KOMP)Vlcg UC Davis Hematology / Red blood cell distribution width HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.159 Success
Gnpda2tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Ears HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Gnpda2tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Skin color - snout HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Gnpda2tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Coat - hair texture / appearance - back HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Gnpda2tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Forelimb digit - number HOM 8f:7m Fisher Exact Test framework 1.00 Success
Gnpda2tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Tail - presence HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Gnpda2tm1.1(KOMP)Vlcg UC Davis Clinical Chemistry / HDL-cholesterol HOM 1f:5m Not processed 1.00 FAILED - Not enough data points in dependent variable 'IMPC_CBC_016_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Gnpda2tm1.1(KOMP)Vlcg UC Davis Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI2 HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0314 Success
Gnpda2tm1.1(KOMP)Vlcg UC Davis Insulin Blood Level / Insulin HOM 7f:7m Mixed Model framework, generalized least squares, equation withoutWeight 0.790 Success
Gnpda2tm1.1(KOMP)Vlcg UC Davis Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - S HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.412 Success
Gnpda2tm1.1(KOMP)Vlcg UC Davis Open Field / Periphery average speed HOM 0f:5m Mixed Model framework, generalized least squares, equation withoutWeight 0.00432 Success
Gnpda2tm1.1(KOMP)Vlcg UC Davis Open Field / Periphery average speed HOM 8f:2m Not processed 1.00 FAILED - Not enough data points in dependent variable 'IMPC_OFD_013_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Gnpda2tm1.1(KOMP)Vlcg UC Davis Fertility of Homozygous Knock-out Mice / Gross Findings Male HOM f:m Supplied as data Success
Gnpda2tm1.1(KOMP)Vlcg UC Davis X-ray / Processes on vertebrae HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Gnpda2tm1.1(KOMP)Vlcg UC Davis X-ray / Tibia length HOM 5f:5m Mixed Model framework, generalized least squares, equation withWeight 0.269 Success
Gnpda2tm1.1(KOMP)Vlcg UC Davis Body Composition (DEXA lean/fat) / Lean mass HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.634 Success
Gnpda2tm1.1(KOMP)Vlcg UC Davis Open Field / Whole arena average speed HOM 0f:5m Mixed Model framework, generalized least squares, equation withoutWeight 0.00400 Success
Gnpda2tm1.1(KOMP)Vlcg UC Davis Open Field / Whole arena average speed HOM 8f:2m Not processed 1.00 FAILED - Not enough data points in dependent variable 'IMPC_OFD_009_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Gnpda2tm1.1(KOMP)Vlcg UC Davis X-ray / Maxilla/Pre-maxilla HOM 5f:5m Fisher Exact Test framework 1.00 Success
Gnpda2tm1.1(KOMP)Vlcg UC Davis X-ray / Number of pelvic vertebrae HOM 5f:5m Not processed 1.00 FAILED - No variability in dependent variable 'IMPC_XRY_016_001'.
Gnpda2tm1.1(KOMP)Vlcg UC Davis Hematology / Lymphocyte differential count HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.00824 Success
Gnpda2tm1.1(KOMP)Vlcg UC Davis Hematology / White blood cell count HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.506 Success
Gnpda2tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Skin color - tail HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Gnpda2tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Mouth morphology HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 4 No  (2/584)  (3/4) N/A
Aorta 4 No  (1/4) N/A
Blood 4 No N/A
Bone marrow 4 No N/A
Brain 4 No  (2/4) N/A
Brainstem 4 No N/A
Brown adipose tissue 4 No N/A
Cartilage tissue 4 No N/A
Cecum 4 No  (12/383)  (3/4) N/A
Cerebellum 4 No  (4/4) N/A
Cerebral cortex 4 No N/A
Chest bone 4 No N/A
Colon 4 No  (12/127)  (3/4) N/A
Diaphragm 4 No N/A
Duodenum 4 No  (2/127)  (1/4) N/A
Epididymis 4 No  (18/134)  (2/4) N/A
Esophagus 4 No  (7/415)  (2/4) N/A
Eye 4 No  (2/4) N/A
Gall bladder 4 No N/A
Gonadal fat pad 4 No N/A
Harderian gland 4 No  (1/4) N/A
Heart 4 No N/A
Hindlimb 4 No N/A
Hippocampus 4 No N/A
Hypothalamus 4 No N/A
Ileum 4 No  (14/127)  (3/4) N/A
Jejunum 4 No  (6/127)  (2/4) N/A
Kidney 4 No  (18/584)  (4/4) N/A
Large intestine 4 No  (10/584) N/A
Liver 4 No N/A
Lower urinary tract 4 No N/A
Lung 4 No  (3/4) N/A
Lymph node 4 No N/A
Mammary gland 4 No N/A
Mesenteric adipose tissue 4 No N/A
Mesenteric lymph node 4 No N/A
Midbrain 4 No  (4/4) N/A
Olfactory lobe 4 No  (4/4) N/A
Ovary 4 No  (1/584)  (2/4) N/A
Oviduct 4 No  (2/4) N/A
Pancreas 4 No  (5/584)  (1/4) N/A
Parathyroid gland 4 No  (3/4) N/A
Parotid gland 4 No  (1/4) N/A
Penis 4 No  (1/4) N/A
Peripheral nervous system 4 No N/A
Peyer's patch 4 No N/A
Pituitary gland 4 No  (3/4) N/A
Prostate gland 4 No  (12/584) N/A
Quadriceps 4 No  (1/4) N/A
Sciatic nerve 4 No  (1/4) N/A
Skeletal muscle 4 No N/A
Skin 4 No  (3/4) N/A
Small intestine 4 No  (9/584) N/A
Spinal cord 4 No  (4/4) N/A
Spleen 4 No  (2/584)  (1/4) N/A
Stomach 4 No  (12/584)  (3/4) N/A
Stomach pyloric region 4 No N/A
Striatum 4 No N/A
Sublingual gland 4 No  (2/4) N/A
Submandibular gland 4 No  (2/132) N/A
Testis 4 No  (2/584)  (2/4) N/A
Thymus 4 No  (4/4) N/A
Thyroid gland 4 No  (15/584)  (2/4) N/A
Tongue 4 No  (5/127)  (1/4) N/A
Trachea 4 No  (4/4) N/A
Trigeminal V nerve 4 No  (2/4) N/A
Urinary bladder 4 No  (3/4) N/A
Uterus 4 No  (1/4) N/A
Vagina 4 No  (1/4) N/A
Vas deferens 4 No  (15/388)  (2/4) N/A
Vascular system 4 No N/A
Vesicular gland 4 No  (1/4) N/A
White adipose tissue 4 No N/A
No Embryo expression data was found for this gene.

 Associated Images

X-ray: XRay Images Dorso Ventral
40 Images
X-ray: XRay Images Lateral Orientation
20 Images

 Disease Models

No associations by disease annotation and gene orthology found.
Please visit the desktop version to see this section

 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Gnpda2tm1.1(KOMP)Vlcg Reporter-tagged deletion allele (post Cre, with no selection cassette) Mice, Tissue
Gnpda2tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Mice, Targeting vectors, ES Cells
Gnpda2tm1(KOMP)Wtsi Reporter-tagged deletion allele (with selection cassette) Targeting vectors, ES Cells
Gnpda2tm455746(L1L2_GT1_LF2A_LacZ_BetactP_neo) Targeting vectors

The IMPC Newsletter

Get highlights of the most important data releases, news and events, delivered straight to your email inbox

Subscribe to newsletter