Gene: Tmem100

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Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
increased leukocyte cell number Tmem100tm1e.1(KOMP)Wtsi HET postnatal 8.49×10-06
abnormal embryo size Tmem100tm1e.1(KOMP)Wtsi HET embryonic day 9.5 0.00
abnormal neural tube closure Tmem100tm1e.1(KOMP)Wtsi HET embryonic day 9.5 0.00
pale yolk sac Tmem100tm1e.1(KOMP)Wtsi HOM embryonic day 9.5 0.00
edema Tmem100tm1e.1(KOMP)Wtsi HOM embryonic day 9.5 0.00
abnormal midbrain development Tmem100tm1e.1(KOMP)Wtsi HET embryonic day 9.5 0.00
abnormal hindbrain development Tmem100tm1e.1(KOMP)Wtsi HET embryonic day 9.5 0.00
pallor Tmem100tm1e.1(KOMP)Wtsi HET embryonic day 9.5 0.00
abnormal pericardium morphology Tmem100tm1e.1(KOMP)Wtsi HOM embryonic day 9.5 0.00
abnormal embryo size Tmem100tm1e.1(KOMP)Wtsi HOM embryonic day 9.5 0.00
embryonic lethality prior to tooth bud stage Tmem100tm1e.1(KOMP)Wtsi HOM embryonic day 12.5 0.00
abnormal lung morphology Tmem100tm1e.1(KOMP)Wtsi HET postnatal 0.00
abnormal forebrain development Tmem100tm1e.1(KOMP)Wtsi HET embryonic day 9.5 0.00
abnormal embryo size Tmem100tm1e.1(KOMP)Wtsi HET embryonic day 12.5 0.00
preweaning lethality, complete penetrance Tmem100tm1e.1(KOMP)Wtsi HOM n/a 0.00

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Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584) N/A
Aorta 2 No N/A
Bone 2 No  Section images
Brain 2 No N/A
Brainstem 2 No N/A
Cartilage tissue 2 No N/A
Cerebellum 2 No N/A
Cerebral cortex 2 No N/A
Esophagus 2 No  (7/415) N/A
Eye 2 No N/A
Heart 2 No N/A
Hippocampus 2 No N/A
Hypothalamus 2 No N/A
Kidney 2 No  (18/584)  (2/2) N/A
Large intestine 2 No  (10/584)  (2/2) N/A
Liver 2 No N/A
Lower urinary tract 2 No  (1/2) N/A
Lung 2 No  (2/2)  Section images
Lymph node 2 No N/A
Mammary gland 2 No N/A
Olfactory lobe 2 No N/A
Ovary 2 No  (1/584) N/A
Oviduct 2 No  (1/2)  Section images
Pancreas 2 No  (5/584) N/A
Peripheral nervous system 2 No N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No N/A
Prostate gland 2 No  (12/584)  (1/2) N/A
Skeletal muscle 2 No N/A
Skin 2 No N/A
Small intestine 2 No  (9/584)  (1/2) N/A
Spinal cord 2 No  Section images
Spleen 2 No  (2/584) N/A
Stomach 2 No  (12/584)  (2/2) N/A
Striatum 2 No N/A
Testis 2 No  (2/584)  (1/2) N/A
Thymus 2 No N/A
Thyroid gland 2 No  (15/584)  (2/2) N/A
Tongue 2 No  (5/127)  Section images
Trachea 2 No N/A
Uterus 2 No  (1/2)  Section images
Vascular system 2 No N/A
White adipose tissue 2 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Axial skeleton 2  (1/51) N/A
Brain 2  (6/485) N/A
Central nervous system ganglion 2  (1/51) N/A
Ear 2  (1/485) N/A
Embryo 2  (1/485)  (2/2) N/A
Eye 2  (1/485) N/A
Foot 2  (1/485) N/A
Forebrain 2  (1/485) N/A
Forelimb 2  (1/485)  (2/2) N/A
Gut 2  (1/50) N/A
Hand 2  (1/485) N/A
Head 2  (5/485) N/A
Heart 2  (1/485)  (2/2) N/A
Hindbrain 2  (6/485) N/A
Hindlimb 2  (1/485) N/A
Liver 2  (1/485) N/A
Lung 2  (1/485) N/A
Mandibular process 2  (1/485) N/A
Maxillary process 2  (1/485) N/A
Midbrain 2  (1/485) N/A
Nose 2  (1/51)  (2/2) N/A
Oral cavity 2  (1/485) N/A
Skeleton 2  (1/51) N/A
Skin 2  (1/485) N/A
Spinal cord 2  (1/50) N/A
Tail 2  (1/485) N/A
Tail somite 2  (1/485) N/A
Trachea 2  (1/50)  (2/2) N/A
Urinary system 2  (1/50) N/A

 Associated Images

X-ray: XRay Images Lateral Orientation
28 Images
Combined SHIRPA and Dysmorphology
3 Images
Gross Morphology Embryo E9.5
12 Images
X-ray: XRay Images Hind Leg and Hip
14 Images
Gross Pathology and Tissue Collection
8 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
14 Images
X-ray: XRay Images Dorso Ventral
14 Images
Adult LacZ: LacZ Images Section
23 Images
Eye Morphology: Images Ophthalmoscopy
4 Images
Eye Morphology: Images Slit Lamp
1 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Tmem100tm1e(KOMP)Wtsi Targeted, non-conditional allele Mice
Tmem100tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells
Tmem100tm43147(L1L2_gt0) Targeting vectors
Tmem100tm1e.1(KOMP)Wtsi Mice, Tissue

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