Gene Summary
IMPC Data Collections
- Body Weight Measurements
- No Embryo Imaging Data
- Viability Data
The IMPC applies a panel of phenotyping screens to characterise single-gene knockout mice by comparison to wild types. Click on the different tabs to visualise significant phenotypes identified by the IMPC, as well as all data that was measured.
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
The table below shows human diseases associated to Cfap410 by orthology or direct annotation.
Disease | Similarity of phenotypes |
Matching phenotypes | Source |
---|---|---|---|
Cone Rod Dystrophy | ORPHA:1872 | ||
Retinal Dystrophy With Or Without Macular Staphyloma | OMIM:617547 | ||
Amyotrophic Lateral Sclerosis | ORPHA:803 | ||
Spondylometaphyseal Dysplasia, Axial | OMIM:602271 |
The table below shows human diseases predicted to be associated to Cfap410 by phenotypic similarity.
Disease | Similarity of phenotypes |
Matching phenotypes | Source |
---|---|---|---|
Cone Rod Dystrophy | ORPHA:1872 | ||
Retinal Dystrophy With Or Without Macular Staphyloma | OMIM:617547 | ||
Amyotrophic Lateral Sclerosis | ORPHA:803 | ||
Spondylometaphyseal Dysplasia, Axial | OMIM:602271 |
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MGI Allele | Allele Type | Produced |
---|---|---|
Cfap410tm2a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | Targeting vectors, ES Cells |
Cfap410tm1b(EUCOMM)Wtsi | Reporter-tagged deletion allele (with selection cassette) | Mice |
Cfap410tm40868(L1L2_gt0) | KO first allele (reporter-tagged insertion with conditional potential) | Targeting vectors |
Cfap410tm1e(EUCOMM)Wtsi | Targeted, non-conditional allele | ES Cells |
Cfap410tm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | Mice, Targeting vectors, ES Cells |
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