Gene: Rnls

Name
renalase, FAD-dependent amine oxidase
MGI ID
MGI:1915045
Synonyms
6530404N21Rik
Viability
Homozygous - Viable
Other links
Significant phenotypes (0) All measurements (337) Expression & images (0) Disease models (0) Order (2)
View data by physiological system
Significant
Not Significant
Not tested

Filtered by: all phenotypes

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Allele Center Procedure / Parameter Zygosity Mutants Statistical
Method
P Value Status
Rnlstm1b(EUCOMM)Wtsi HMGU Combined SHIRPA and Dysmorphology / Forelimb digit - size HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnlstm1b(EUCOMM)Wtsi HMGU Combined SHIRPA and Dysmorphology / Tail - thickness HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnlstm1b(EUCOMM)Wtsi HMGU Clinical Chemistry / Alanine aminotransferase HOM 10f:10m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.610 Success
Rnlstm1b(EUCOMM)Wtsi HMGU Combined SHIRPA and Dysmorphology / Coat - hair distribution - back HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnlstm1b(EUCOMM)Wtsi HMGU Echo / LVPWd HOM 10f:6m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0905 Success
Rnlstm1b(EUCOMM)Wtsi HMGU Clinical Chemistry / Lipase HOM 10f:10m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.938 Success
Rnlstm1b(EUCOMM)Wtsi HMGU Eye Morphology / Bulging eye HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnlstm1b(EUCOMM)Wtsi HMGU Combined SHIRPA and Dysmorphology / Forelimb nail - shape HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnlstm1b(EUCOMM)Wtsi HMGU Electrocardiogram (ECG) / RR HOM 10f:6m Mixed Model framework, linear mixed-effects model, equation withWeight 0.452 Success
Rnlstm1b(EUCOMM)Wtsi HMGU Combined SHIRPA and Dysmorphology / Skin texture - whole body HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnlstm1b(EUCOMM)Wtsi HMGU Combined SHIRPA and Dysmorphology / Trunk curl HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnlstm1b(EUCOMM)Wtsi HMGU Clinical Chemistry / Creatinine HOM 10f:10m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0172 Success
Rnlstm1b(EUCOMM)Wtsi HMGU Eye Morphology / Iris/Pupil HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnlstm1b(EUCOMM)Wtsi HMGU X-ray / Number of thoracic vertebrae HOM 5f:5m Not processed 1.00 FAILED - No variability in dependent variable 'IMPC_XRY_014_001'.
Rnlstm1b(EUCOMM)Wtsi HMGU Hematology / Mean cell hemoglobin concentration HOM 10f:10m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.679 Success
Rnlstm1b(EUCOMM)Wtsi HMGU X-ray / Radius HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnlstm1b(EUCOMM)Wtsi HMGU Eye Morphology / Corneal deposits HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnlstm1b(EUCOMM)Wtsi HMGU Indirect Calorimetry / Total food intake HOM 10f:10m Mixed Model framework, linear mixed-effects model, equation withWeight 0.285 Success
Rnlstm1b(EUCOMM)Wtsi HMGU X-ray / Fibula HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnlstm1b(EUCOMM)Wtsi HMGU Open Field / Percentage center time HOM 10f:10m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.273 Success
Rnlstm1b(EUCOMM)Wtsi HMGU Hematology / Mean platelet volume HOM 10f:10m Mixed Model framework, linear mixed-effects model, equation withWeight 0.610 Success
Rnlstm1b(EUCOMM)Wtsi HMGU Auditory Brain Stem Response / 6kHz-evoked ABR Threshold HOM 4f:4m 0.236 Success
Rnlstm1b(EUCOMM)Wtsi HMGU X-ray / Shape of vertebrae HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnlstm1b(EUCOMM)Wtsi HMGU X-ray / Brachydactyly HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnlstm1b(EUCOMM)Wtsi HMGU Combined SHIRPA and Dysmorphology / Vibrissae - presence HOM 10f:10m Fisher Exact Test framework 1.00 Success
Rnlstm1b(EUCOMM)Wtsi HMGU Gross Pathology and Tissue Collection / Thyroid HOM f:m Supplied as data Success
Rnlstm1b(EUCOMM)Wtsi HMGU Gross Pathology and Tissue Collection / Thyroid HOM f:m Supplied as data Success
Rnlstm1b(EUCOMM)Wtsi HMGU Gross Pathology and Tissue Collection / Thyroid HOM f:m Supplied as data Success
Rnlstm1b(EUCOMM)Wtsi HMGU Gross Pathology and Tissue Collection / Thyroid HOM f:m Supplied as data Success
Rnlstm1b(EUCOMM)Wtsi HMGU Combined SHIRPA and Dysmorphology / Lower teeth appearance HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnlstm1b(EUCOMM)Wtsi HMGU X-ray / Scapulae HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnlstm1b(EUCOMM)Wtsi HMGU Combined SHIRPA and Dysmorphology / Skin texture - back paws HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnlstm1b(EUCOMM)Wtsi HMGU Combined SHIRPA and Dysmorphology / Forelimbs - shape HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnlstm1b(EUCOMM)Wtsi HMGU Open Field / Periphery distance travelled HOM 10f:10m Mixed Model framework, linear mixed-effects model, equation withWeight 0.529 Success
Rnlstm1b(EUCOMM)Wtsi HMGU Eye Morphology / Retina (combined) HOM 10f:10m Not processed Success
Rnlstm1b(EUCOMM)Wtsi HMGU X-ray / Zygomatic bone HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnlstm1b(EUCOMM)Wtsi HMGU Gross Pathology and Tissue Collection / Spleen HOM f:m Supplied as data Success
Rnlstm1b(EUCOMM)Wtsi HMGU Gross Pathology and Tissue Collection / Spleen HOM f:m Supplied as data Success
Rnlstm1b(EUCOMM)Wtsi HMGU Gross Pathology and Tissue Collection / Spleen HOM f:m Supplied as data Success
Rnlstm1b(EUCOMM)Wtsi HMGU Gross Pathology and Tissue Collection / Spleen HOM f:m Supplied as data Success
Rnlstm1b(EUCOMM)Wtsi HMGU Clinical Chemistry / Calcium HOM 10f:10m Mixed Model framework, linear mixed-effects model, equation withWeight 0.150 Success
Rnlstm1b(EUCOMM)Wtsi HMGU Echo / HR HOM 10f:6m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0480 Success
Rnlstm1b(EUCOMM)Wtsi HMGU X-ray / Shape of ribs HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnlstm1b(EUCOMM)Wtsi HMGU Gross Pathology and Tissue Collection / Epididymis HOM f:m Supplied as data Success
Rnlstm1b(EUCOMM)Wtsi HMGU Gross Pathology and Tissue Collection / Epididymis HOM f:m Supplied as data Success
Rnlstm1b(EUCOMM)Wtsi HMGU Combined SHIRPA and Dysmorphology / Contact righting HOM 10f:10m Fisher Exact Test framework 1.00 Success
Rnlstm1b(EUCOMM)Wtsi HMGU Hematology / Hematocrit HOM 10f:10m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0282 Success
Rnlstm1b(EUCOMM)Wtsi HMGU Combined SHIRPA and Dysmorphology / Hindlimb nail - number HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnlstm1b(EUCOMM)Wtsi HMGU Combined SHIRPA and Dysmorphology / Skin color - ear HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnlstm1b(EUCOMM)Wtsi HMGU Gross Pathology and Tissue Collection / Esophagus HOM f:m Supplied as data Success
Rnlstm1b(EUCOMM)Wtsi HMGU Gross Pathology and Tissue Collection / Esophagus HOM f:m Supplied as data Success
Rnlstm1b(EUCOMM)Wtsi HMGU Gross Pathology and Tissue Collection / Esophagus HOM f:m Supplied as data Success
Rnlstm1b(EUCOMM)Wtsi HMGU Gross Pathology and Tissue Collection / Esophagus HOM f:m Supplied as data Success
Rnlstm1b(EUCOMM)Wtsi HMGU Grip Strength / Forelimb and hindlimb grip strength normalised against body weight HOM 10f:10m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.527 Success
Rnlstm1b(EUCOMM)Wtsi HMGU Combined SHIRPA and Dysmorphology / Coat - hair texture / appearance - head HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnlstm1b(EUCOMM)Wtsi HMGU Intraperitoneal glucose tolerance test (IPGTT) / Area under glucose response curve HOM 10f:10m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.993 Success
Rnlstm1b(EUCOMM)Wtsi HMGU Combined SHIRPA and Dysmorphology / Coat - color - abdomen HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnlstm1b(EUCOMM)Wtsi HMGU Eye Morphology / Pupil Dilation HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnlstm1b(EUCOMM)Wtsi HMGU Body Composition (DEXA lean/fat) / Fat mass HOM 10f:10m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.00783 Success
Rnlstm1b(EUCOMM)Wtsi HMGU Clinical Chemistry / Potassium HOM 10f:10m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0690 Success
Rnlstm1b(EUCOMM)Wtsi HMGU Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI3 HOM 10f:10m Mixed Model framework, linear mixed-effects model, equation withWeight 0.997 Success
Rnlstm1b(EUCOMM)Wtsi HMGU Auditory Brain Stem Response / 30kHz-evoked ABR Threshold HOM 4f:4m 0.280 Success
Rnlstm1b(EUCOMM)Wtsi HMGU Clinical Chemistry / Phosphorus HOM 10f:10m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.720 Success
Rnlstm1b(EUCOMM)Wtsi HMGU Combined SHIRPA and Dysmorphology / Hindpaw - shape HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnlstm1b(EUCOMM)Wtsi HMGU Combined SHIRPA and Dysmorphology / Tremor HOM 10f:10m Fisher Exact Test framework 1.00 Success
Rnlstm1b(EUCOMM)Wtsi HMGU Viability Primary Screen / Outcome HOM 27f:29m Supplied as data Success
Rnlstm1b(EUCOMM)Wtsi HMGU Combined SHIRPA and Dysmorphology / Genitalia - morphology HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnlstm1b(EUCOMM)Wtsi HMGU Gross Pathology and Tissue Collection / Brain HOM f:m Supplied as data Success
Rnlstm1b(EUCOMM)Wtsi HMGU Gross Pathology and Tissue Collection / Brain HOM f:m Supplied as data Success
Rnlstm1b(EUCOMM)Wtsi HMGU Gross Pathology and Tissue Collection / Brain HOM f:m Supplied as data Success
Rnlstm1b(EUCOMM)Wtsi HMGU Gross Pathology and Tissue Collection / Brain HOM f:m Supplied as data Success
Rnlstm1b(EUCOMM)Wtsi HMGU Gross Pathology and Tissue Collection / Lymph node HOM f:m Supplied as data Success
Rnlstm1b(EUCOMM)Wtsi HMGU Gross Pathology and Tissue Collection / Lymph node HOM f:m Supplied as data Success
Rnlstm1b(EUCOMM)Wtsi HMGU Gross Pathology and Tissue Collection / Lymph node HOM f:m Supplied as data Success
Rnlstm1b(EUCOMM)Wtsi HMGU Gross Pathology and Tissue Collection / Lymph node HOM f:m Supplied as data Success
Rnlstm1b(EUCOMM)Wtsi HMGU Combined SHIRPA and Dysmorphology / Head morphology HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnlstm1b(EUCOMM)Wtsi HMGU Indirect Calorimetry / Respiratory Exchange Ratio HOM 10f:10m Mixed Model framework, linear mixed-effects model, equation withWeight 0.231 Success
Rnlstm1b(EUCOMM)Wtsi HMGU Combined SHIRPA and Dysmorphology / Upper teeth appearance HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnlstm1b(EUCOMM)Wtsi HMGU Open Field / Center distance travelled HOM 10f:10m Mixed Model framework, linear mixed-effects model, equation withWeight 0.584 Success
Rnlstm1b(EUCOMM)Wtsi HMGU Auditory Brain Stem Response / 18kHz-evoked ABR Threshold HOM 4f:4m 1.00 Success
Rnlstm1b(EUCOMM)Wtsi HMGU Eye Morphology / Corneal vascularization HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnlstm1b(EUCOMM)Wtsi HMGU Eye Morphology / Retinal Blood Vessels Pattern HOM 10f:10m Fisher Exact Test framework 0.00477 Success
Rnlstm1b(EUCOMM)Wtsi HMGU Clinical Chemistry / Triglycerides HOM 10f:10m Mixed Model framework, linear mixed-effects model, equation withWeight 0.589 Success
Rnlstm1b(EUCOMM)Wtsi HMGU Eye Morphology / Right total retinal thickness HOM 9f:10m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.983 Success
Rnlstm1b(EUCOMM)Wtsi HMGU X-ray / Clavicle HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnlstm1b(EUCOMM)Wtsi HMGU Hematology / Platelet count HOM 10f:10m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.919 Success
Rnlstm1b(EUCOMM)Wtsi HMGU Combined SHIRPA and Dysmorphology / Activity (body position) HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnlstm1b(EUCOMM)Wtsi HMGU Gross Pathology and Tissue Collection / Liver HOM f:m Supplied as data Success
Rnlstm1b(EUCOMM)Wtsi HMGU Gross Pathology and Tissue Collection / Liver HOM f:m Supplied as data Success
Rnlstm1b(EUCOMM)Wtsi HMGU Gross Pathology and Tissue Collection / Liver HOM f:m Supplied as data Success
Rnlstm1b(EUCOMM)Wtsi HMGU Gross Pathology and Tissue Collection / Liver HOM f:m Supplied as data Success
Rnlstm1b(EUCOMM)Wtsi HMGU Combined SHIRPA and Dysmorphology / Hindlimb digit - size HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnlstm1b(EUCOMM)Wtsi HMGU X-ray / Digit integrity HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnlstm1b(EUCOMM)Wtsi HMGU Gross Pathology and Tissue Collection / Thymus HOM f:m Supplied as data Success
Rnlstm1b(EUCOMM)Wtsi HMGU Gross Pathology and Tissue Collection / Thymus HOM f:m Supplied as data Success
Rnlstm1b(EUCOMM)Wtsi HMGU Gross Pathology and Tissue Collection / Thymus HOM f:m Supplied as data Success
Rnlstm1b(EUCOMM)Wtsi HMGU Gross Pathology and Tissue Collection / Thymus HOM f:m Supplied as data Success
Rnlstm1b(EUCOMM)Wtsi HMGU Combined SHIRPA and Dysmorphology / Skin texture - snout HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnlstm1b(EUCOMM)Wtsi HMGU Clinical Chemistry / Total protein HOM 10f:10m Mixed Model framework, linear mixed-effects model, equation withWeight 0.800 Success
Rnlstm1b(EUCOMM)Wtsi HMGU Echo / Respiration Rate HOM 9f:6m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0208 Success
Rnlstm1b(EUCOMM)Wtsi HMGU Eye Morphology / Pupil Position HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnlstm1b(EUCOMM)Wtsi HMGU Body Composition (DEXA lean/fat) / Fat/Body weight HOM 10f:10m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.198 Success
Rnlstm1b(EUCOMM)Wtsi HMGU Combined SHIRPA and Dysmorphology / Hindlimbs - position HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnlstm1b(EUCOMM)Wtsi HMGU X-ray / Number of cervical vertebrae HOM 5f:5m Not processed 1.00 FAILED - No variability in dependent variable 'IMPC_XRY_013_001'.
Rnlstm1b(EUCOMM)Wtsi HMGU Open Field / Latency to center entry HOM 10f:10m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0632 Success
Rnlstm1b(EUCOMM)Wtsi HMGU Eye Morphology / Eyelid closure HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnlstm1b(EUCOMM)Wtsi HMGU Combined SHIRPA and Dysmorphology / Forelimbs - size HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnlstm1b(EUCOMM)Wtsi HMGU Echo / LVIDd HOM 10f:6m Mixed Model framework, linear mixed-effects model, equation withWeight 0.420 Success
Rnlstm1b(EUCOMM)Wtsi HMGU X-ray / Fusion of vertebrae HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnlstm1b(EUCOMM)Wtsi HMGU Gross Pathology and Tissue Collection / Mammary gland HOM f:m Supplied as data Success
Rnlstm1b(EUCOMM)Wtsi HMGU Gross Pathology and Tissue Collection / Mammary gland HOM f:m Supplied as data Success
Rnlstm1b(EUCOMM)Wtsi HMGU X-ray / Tibia HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnlstm1b(EUCOMM)Wtsi HMGU Combined SHIRPA and Dysmorphology / Tail - morphology HOM 10f:10m Fisher Exact Test framework 1.00 Success
Rnlstm1b(EUCOMM)Wtsi HMGU Combined SHIRPA and Dysmorphology / Coat - color pattern - abdomen HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnlstm1b(EUCOMM)Wtsi HMGU Eye Morphology / Iris transilumination HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnlstm1b(EUCOMM)Wtsi HMGU Clinical Chemistry / Aspartate aminotransferase HOM 10f:10m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.827 Success
Rnlstm1b(EUCOMM)Wtsi HMGU Combined SHIRPA and Dysmorphology / Hindlimb nail - length HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnlstm1b(EUCOMM)Wtsi HMGU Combined SHIRPA and Dysmorphology / Vocalization HOM 10f:10m Fisher Exact Test framework 0.472 Success
Rnlstm1b(EUCOMM)Wtsi HMGU Grip Strength / Forelimb and hindlimb grip strength measurement mean HOM 10f:10m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.00250 Success
Rnlstm1b(EUCOMM)Wtsi HMGU Hematology / Hemoglobin HOM 10f:10m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0320 Success
Rnlstm1b(EUCOMM)Wtsi HMGU Open Field / Whole arena resting time HOM 10f:10m Mixed Model framework, linear mixed-effects model, equation withWeight 0.495 Success
Rnlstm1b(EUCOMM)Wtsi HMGU X-ray / Syndactylism HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnlstm1b(EUCOMM)Wtsi HMGU Eye Morphology / Vitreous HOM 10f:10m Fisher Exact Test framework 0.109 Success
Rnlstm1b(EUCOMM)Wtsi HMGU Combined SHIRPA and Dysmorphology / Teeth presence HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnlstm1b(EUCOMM)Wtsi HMGU Eye Morphology / Lens HOM 10f:10m Fisher Exact Test framework 1.00 Success
Rnlstm1b(EUCOMM)Wtsi HMGU Electrocardiogram (ECG) / QTc HOM 10f:6m Mixed Model framework, linear mixed-effects model, equation withWeight 0.353 Success
Rnlstm1b(EUCOMM)Wtsi HMGU Grip Strength / Forelimb grip strength normalised against body weight HOM 10f:10m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.460 Success
Rnlstm1b(EUCOMM)Wtsi HMGU Combined SHIRPA and Dysmorphology / Head size HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnlstm1b(EUCOMM)Wtsi HMGU Eye Morphology / Optic Disc HOM 10f:10m Fisher Exact Test framework 0.130 Success
Rnlstm1b(EUCOMM)Wtsi HMGU Combined SHIRPA and Dysmorphology / Coat - color pattern - back HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnlstm1b(EUCOMM)Wtsi HMGU Open Field / Center average speed HOM 10f:10m Mixed Model framework, linear mixed-effects model, equation withWeight 0.170 Success
Rnlstm1b(EUCOMM)Wtsi HMGU Eye Morphology / Narrow eye opening HOM 10f:10m Fisher Exact Test framework 0.0645 Success
Rnlstm1b(EUCOMM)Wtsi HMGU Clinical Chemistry / Sodium HOM 10f:10m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.890 Success
Rnlstm1b(EUCOMM)Wtsi HMGU Heart Weight / Heart weight HOM 5f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.164 Success
Rnlstm1b(EUCOMM)Wtsi HMGU Heart Weight / Heart weight HOM 5f:2m Not processed 1.00 FAILED - Not enough data points in dependent variable 'IMPC_HWT_008_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Rnlstm1b(EUCOMM)Wtsi HMGU Combined SHIRPA and Dysmorphology / Forepaw - shape HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnlstm1b(EUCOMM)Wtsi HMGU Body Composition (DEXA lean/fat) / Bone Mineral Content (excluding skull) HOM 10f:10m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.00346 Success
Rnlstm1b(EUCOMM)Wtsi HMGU Gross Pathology and Tissue Collection / Prostate HOM f:m Supplied as data Success
Rnlstm1b(EUCOMM)Wtsi HMGU Gross Pathology and Tissue Collection / Prostate HOM f:m Supplied as data Success
Rnlstm1b(EUCOMM)Wtsi HMGU Combined SHIRPA and Dysmorphology / Skin color - snout HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnlstm1b(EUCOMM)Wtsi HMGU Gross Pathology and Tissue Collection / Skin HOM f:m Supplied as data Success
Rnlstm1b(EUCOMM)Wtsi HMGU Gross Pathology and Tissue Collection / Skin HOM f:m Supplied as data Success
Rnlstm1b(EUCOMM)Wtsi HMGU Gross Pathology and Tissue Collection / Skin HOM f:m Supplied as data Success
Rnlstm1b(EUCOMM)Wtsi HMGU Gross Pathology and Tissue Collection / Skin HOM f:m Supplied as data Success
Rnlstm1b(EUCOMM)Wtsi HMGU Combined SHIRPA and Dysmorphology / Coat - hair texture / appearance - back HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnlstm1b(EUCOMM)Wtsi HMGU Gross Pathology and Tissue Collection / Lung HOM f:m Supplied as data Success
Rnlstm1b(EUCOMM)Wtsi HMGU Gross Pathology and Tissue Collection / Lung HOM f:m Supplied as data Success
Rnlstm1b(EUCOMM)Wtsi HMGU Gross Pathology and Tissue Collection / Lung HOM f:m Supplied as data Success
Rnlstm1b(EUCOMM)Wtsi HMGU Gross Pathology and Tissue Collection / Lung HOM f:m Supplied as data Success
Rnlstm1b(EUCOMM)Wtsi HMGU Clinical Chemistry / HDL-cholesterol HOM 10f:10m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0918 Success
Rnlstm1b(EUCOMM)Wtsi HMGU Eye Morphology / Persistence of hyaloid vascular system HOM 10f:10m Fisher Exact Test framework 0.0421 Success
Rnlstm1b(EUCOMM)Wtsi HMGU Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI2 HOM 10f:10m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.990 Success
Rnlstm1b(EUCOMM)Wtsi HMGU Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - S HOM 10f:10m Mixed Model framework, linear mixed-effects model, equation withWeight 0.353 Success
Rnlstm1b(EUCOMM)Wtsi HMGU Eye Morphology / Pupil Shape HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnlstm1b(EUCOMM)Wtsi HMGU Electrocardiogram (ECG) / QTc Dispersion HOM 10f:6m Mixed Model framework, generalized least squares, equation withoutWeight 0.418 Success
Rnlstm1b(EUCOMM)Wtsi HMGU Open Field / Periphery average speed HOM 10f:10m Mixed Model framework, linear mixed-effects model, equation withWeight 0.636 Success
Rnlstm1b(EUCOMM)Wtsi HMGU X-ray / Processes on vertebrae HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnlstm1b(EUCOMM)Wtsi HMGU Eye Morphology / Eye HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnlstm1b(EUCOMM)Wtsi HMGU X-ray / Maxilla/Pre-maxilla HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnlstm1b(EUCOMM)Wtsi HMGU Gross Pathology and Tissue Collection / Pancreas HOM f:m Supplied as data Success
Rnlstm1b(EUCOMM)Wtsi HMGU Gross Pathology and Tissue Collection / Pancreas HOM f:m Supplied as data Success
Rnlstm1b(EUCOMM)Wtsi HMGU Gross Pathology and Tissue Collection / Pancreas HOM f:m Supplied as data Success
Rnlstm1b(EUCOMM)Wtsi HMGU Gross Pathology and Tissue Collection / Pancreas HOM f:m Supplied as data Success
Rnlstm1b(EUCOMM)Wtsi HMGU Echo / Stroke Volume HOM 10f:6m Mixed Model framework, linear mixed-effects model, equation withWeight 0.691 Success
Rnlstm1b(EUCOMM)Wtsi HMGU Combined SHIRPA and Dysmorphology / Mouth morphology HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnlstm1b(EUCOMM)Wtsi HMGU Combined SHIRPA and Dysmorphology / Head bobbing HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnlstm1b(EUCOMM)Wtsi HMGU Heart Weight / Tibia length HOM 5f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0354 Success
Rnlstm1b(EUCOMM)Wtsi HMGU Heart Weight / Tibia length HOM 5f:2m Not processed 1.00 FAILED - Not enough data points in dependent variable 'IMPC_HWT_002_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Rnlstm1b(EUCOMM)Wtsi HMGU Gross Pathology and Tissue Collection / Spinal cord HOM f:m Supplied as data Success
Rnlstm1b(EUCOMM)Wtsi HMGU Gross Pathology and Tissue Collection / Spinal cord HOM f:m Supplied as data Success
Rnlstm1b(EUCOMM)Wtsi HMGU Gross Pathology and Tissue Collection / Spinal cord HOM f:m Supplied as data Success
Rnlstm1b(EUCOMM)Wtsi HMGU Gross Pathology and Tissue Collection / Spinal cord HOM f:m Supplied as data Success
Rnlstm1b(EUCOMM)Wtsi HMGU Body Composition (DEXA lean/fat) / Lean/Body weight HOM 10f:10m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.415 Success
Rnlstm1b(EUCOMM)Wtsi HMGU X-ray / Number of ribs right HOM 5f:5m Not processed 1.00 FAILED - No variability in dependent variable 'IMPC_XRY_008_001'.
Rnlstm1b(EUCOMM)Wtsi HMGU Combined SHIRPA and Dysmorphology / Skin texture - ear HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnlstm1b(EUCOMM)Wtsi HMGU Open Field / Distance travelled - total HOM 10f:10m Mixed Model framework, linear mixed-effects model, equation withWeight 0.704 Success
Rnlstm1b(EUCOMM)Wtsi HMGU Combined SHIRPA and Dysmorphology / Snout size HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnlstm1b(EUCOMM)Wtsi HMGU Electrocardiogram (ECG) / PR HOM 10f:6m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0189 Success
Rnlstm1b(EUCOMM)Wtsi HMGU Clinical Chemistry / Alpha-amylase HOM 10f:10m Mixed Model framework, linear mixed-effects model, equation withWeight 0.443 Success
Rnlstm1b(EUCOMM)Wtsi HMGU Auditory Brain Stem Response / Click-evoked ABR threshold HOM 4f:4m 0.540 Success
Rnlstm1b(EUCOMM)Wtsi HMGU Eye Morphology / Synechia HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnlstm1b(EUCOMM)Wtsi HMGU Clinical Chemistry / Iron HOM 10f:10m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.328 Success
Rnlstm1b(EUCOMM)Wtsi HMGU Auditory Brain Stem Response / 24kHz-evoked ABR Threshold HOM 4f:4m 1.00 Success
Rnlstm1b(EUCOMM)Wtsi HMGU Clinical Chemistry / Total cholesterol HOM 10f:10m Mixed Model framework, linear mixed-effects model, equation withWeight 0.177 Success
Rnlstm1b(EUCOMM)Wtsi HMGU Combined SHIRPA and Dysmorphology / Genitalia - size HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnlstm1b(EUCOMM)Wtsi HMGU Open Field / Periphery permanence time HOM 10f:10m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.272 Success
Rnlstm1b(EUCOMM)Wtsi HMGU Clinical Chemistry / Albumin HOM 10f:10m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.868 Success
Rnlstm1b(EUCOMM)Wtsi HMGU Combined SHIRPA and Dysmorphology / Forelimb nail - length HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnlstm1b(EUCOMM)Wtsi HMGU Electrocardiogram (ECG) / HR HOM 10f:6m Mixed Model framework, linear mixed-effects model, equation withWeight 0.415 Success
Rnlstm1b(EUCOMM)Wtsi HMGU Intraperitoneal glucose tolerance test (IPGTT) / Initial response to glucose challenge HOM 10f:10m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.697 Success
Rnlstm1b(EUCOMM)Wtsi HMGU Combined SHIRPA and Dysmorphology / Aggression HOM 10f:10m Fisher Exact Test framework 1.00 Success
Rnlstm1b(EUCOMM)Wtsi HMGU Open Field / Number of center entries HOM 10f:10m Mixed Model framework, linear mixed-effects model, equation withWeight 0.409 Success
Rnlstm1b(EUCOMM)Wtsi HMGU X-ray / Pelvis HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnlstm1b(EUCOMM)Wtsi HMGU Gross Pathology and Tissue Collection / Adrenal gland HOM f:m Supplied as data Success
Rnlstm1b(EUCOMM)Wtsi HMGU Gross Pathology and Tissue Collection / Adrenal gland HOM f:m Supplied as data Success
Rnlstm1b(EUCOMM)Wtsi HMGU Gross Pathology and Tissue Collection / Adrenal gland HOM f:m Supplied as data Success
Rnlstm1b(EUCOMM)Wtsi HMGU Gross Pathology and Tissue Collection / Adrenal gland HOM f:m Supplied as data Success
Rnlstm1b(EUCOMM)Wtsi HMGU Grip Strength / Forelimb grip strength measurement mean HOM 10f:10m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.00678 Success
Rnlstm1b(EUCOMM)Wtsi HMGU Combined SHIRPA and Dysmorphology / Hindlimbs - shape HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnlstm1b(EUCOMM)Wtsi HMGU Combined SHIRPA and Dysmorphology / Startle response HOM 10f:10m Fisher Exact Test framework 1.00 Success
Rnlstm1b(EUCOMM)Wtsi HMGU Gross Pathology and Tissue Collection / Urinary bladder HOM f:m Supplied as data Success
Rnlstm1b(EUCOMM)Wtsi HMGU Gross Pathology and Tissue Collection / Urinary bladder HOM f:m Supplied as data Success
Rnlstm1b(EUCOMM)Wtsi HMGU Gross Pathology and Tissue Collection / Urinary bladder HOM f:m Supplied as data Success
Rnlstm1b(EUCOMM)Wtsi HMGU Gross Pathology and Tissue Collection / Urinary bladder HOM f:m Supplied as data Success
Rnlstm1b(EUCOMM)Wtsi HMGU Eye Morphology / Eyelid morphology HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnlstm1b(EUCOMM)Wtsi HMGU Echo / LVPWs HOM 10f:6m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.107 Success
Rnlstm1b(EUCOMM)Wtsi HMGU Combined SHIRPA and Dysmorphology / Forelimb digit - shape HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnlstm1b(EUCOMM)Wtsi HMGU Gross Pathology and Tissue Collection / Gall bladder HOM f:m Supplied as data Success
Rnlstm1b(EUCOMM)Wtsi HMGU Gross Pathology and Tissue Collection / Gall bladder HOM f:m Supplied as data Success
Rnlstm1b(EUCOMM)Wtsi HMGU Gross Pathology and Tissue Collection / Gall bladder HOM f:m Supplied as data Success
Rnlstm1b(EUCOMM)Wtsi HMGU Gross Pathology and Tissue Collection / Gall bladder HOM f:m Supplied as data Success
Rnlstm1b(EUCOMM)Wtsi HMGU Hematology / Mean cell volume HOM 10f:10m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0706 Success
Rnlstm1b(EUCOMM)Wtsi HMGU Combined SHIRPA and Dysmorphology / Coat - color - back HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnlstm1b(EUCOMM)Wtsi HMGU X-ray / Femur HOM 5f:5m Fisher Exact Test framework 1.00 Success
Rnlstm1b(EUCOMM)Wtsi HMGU Eye Morphology / Cornea HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnlstm1b(EUCOMM)Wtsi HMGU Open Field / Center permanence time HOM 10f:10m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.273 Success
Rnlstm1b(EUCOMM)Wtsi HMGU Auditory Brain Stem Response / 12kHz-evoked ABR Threshold HOM 4f:4m 1.00 Success
Rnlstm1b(EUCOMM)Wtsi HMGU Combined SHIRPA and Dysmorphology / Hindpaw - size HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnlstm1b(EUCOMM)Wtsi HMGU Body Composition (DEXA lean/fat) / Bone Mineral Density (excluding skull) HOM 10f:10m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.00378 Success
Rnlstm1b(EUCOMM)Wtsi HMGU Echo / Ejection Fraction HOM 10f:6m Mixed Model framework, linear mixed-effects model, equation withWeight 0.704 Success
Rnlstm1b(EUCOMM)Wtsi HMGU Combined SHIRPA and Dysmorphology / Upper lip morphology HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnlstm1b(EUCOMM)Wtsi HMGU Hematology / Red blood cell count HOM 10f:10m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0568 Success
Rnlstm1b(EUCOMM)Wtsi HMGU Combined SHIRPA and Dysmorphology / Locomotor activity HOM 10f:10m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.813 Success
Rnlstm1b(EUCOMM)Wtsi HMGU Gross Pathology and Tissue Collection / Skeletal muscle HOM f:m Supplied as data Success
Rnlstm1b(EUCOMM)Wtsi HMGU Gross Pathology and Tissue Collection / Skeletal muscle HOM f:m Supplied as data Success
Rnlstm1b(EUCOMM)Wtsi HMGU Gross Pathology and Tissue Collection / Skeletal muscle HOM f:m Supplied as data Success
Rnlstm1b(EUCOMM)Wtsi HMGU Gross Pathology and Tissue Collection / Skeletal muscle HOM f:m Supplied as data Success
Rnlstm1b(EUCOMM)Wtsi HMGU Combined SHIRPA and Dysmorphology / Skin texture - tail HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnlstm1b(EUCOMM)Wtsi HMGU Combined SHIRPA and Dysmorphology / Vibrissae - appearance HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnlstm1b(EUCOMM)Wtsi HMGU Eye Morphology / Iris Pigmentation HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnlstm1b(EUCOMM)Wtsi HMGU Eye Morphology / Retinal Blood Vessels HOM 10f:10m Fisher Exact Test framework 0.00477 Success
Rnlstm1b(EUCOMM)Wtsi HMGU Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI1 HOM 10f:10m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.639 Success
Rnlstm1b(EUCOMM)Wtsi HMGU X-ray / Mandibles HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnlstm1b(EUCOMM)Wtsi HMGU Gross Pathology and Tissue Collection / Seminal vesicle HOM f:m Supplied as data Success
Rnlstm1b(EUCOMM)Wtsi HMGU Gross Pathology and Tissue Collection / Seminal vesicle HOM f:m Supplied as data Success
Rnlstm1b(EUCOMM)Wtsi HMGU X-ray / Humerus HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnlstm1b(EUCOMM)Wtsi HMGU Combined SHIRPA and Dysmorphology / Skin color - back paws HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnlstm1b(EUCOMM)Wtsi HMGU Gross Pathology and Tissue Collection / Large intestine HOM f:m Supplied as data Success
Rnlstm1b(EUCOMM)Wtsi HMGU Gross Pathology and Tissue Collection / Large intestine HOM f:m Supplied as data Success
Rnlstm1b(EUCOMM)Wtsi HMGU Gross Pathology and Tissue Collection / Large intestine HOM f:m Supplied as data Success
Rnlstm1b(EUCOMM)Wtsi HMGU Gross Pathology and Tissue Collection / Large intestine HOM f:m Supplied as data Success
Rnlstm1b(EUCOMM)Wtsi HMGU Combined SHIRPA and Dysmorphology / Limb grasp HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnlstm1b(EUCOMM)Wtsi HMGU Combined SHIRPA and Dysmorphology / Skin color - whole body HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnlstm1b(EUCOMM)Wtsi HMGU X-ray / Number of digits HOM 5f:5m 1.00 Success
Rnlstm1b(EUCOMM)Wtsi HMGU Combined SHIRPA and Dysmorphology / Coat - hair distribution - abdomen HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnlstm1b(EUCOMM)Wtsi HMGU Clinical Chemistry / Urea (Blood Urea Nitrogen - BUN) HOM 10f:10m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0882 Success
Rnlstm1b(EUCOMM)Wtsi HMGU Combined SHIRPA and Dysmorphology / Coat - color pattern - head HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnlstm1b(EUCOMM)Wtsi HMGU Open Field / Periphery resting time HOM 10f:10m Mixed Model framework, linear mixed-effects model, equation withWeight 0.372 Success
Rnlstm1b(EUCOMM)Wtsi HMGU Combined SHIRPA and Dysmorphology / Genitalia - presence HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnlstm1b(EUCOMM)Wtsi HMGU X-ray / Number of lumbar vertebrae HOM 5f:5m 1.00 Success
Rnlstm1b(EUCOMM)Wtsi HMGU Combined SHIRPA and Dysmorphology / Hindlimb nail - shape HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnlstm1b(EUCOMM)Wtsi HMGU X-ray / Ulna HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnlstm1b(EUCOMM)Wtsi HMGU Combined SHIRPA and Dysmorphology / Coat - hair distribution - head HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnlstm1b(EUCOMM)Wtsi HMGU Gross Pathology and Tissue Collection / Uterus HOM f:m Supplied as data Success
Rnlstm1b(EUCOMM)Wtsi HMGU Gross Pathology and Tissue Collection / Uterus HOM f:m Supplied as data Success
Rnlstm1b(EUCOMM)Wtsi HMGU Eye Morphology / Corneal Sclerization HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnlstm1b(EUCOMM)Wtsi HMGU Clinical Chemistry / Alkaline phosphatase HOM 10f:10m Mixed Model framework, linear mixed-effects model, equation withWeight 0.712 Success
Rnlstm1b(EUCOMM)Wtsi HMGU Combined SHIRPA and Dysmorphology / Hindlimb digit - number HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnlstm1b(EUCOMM)Wtsi HMGU Gross Pathology and Tissue Collection / Stomach HOM f:m Supplied as data Success
Rnlstm1b(EUCOMM)Wtsi HMGU Gross Pathology and Tissue Collection / Stomach HOM f:m Supplied as data Success
Rnlstm1b(EUCOMM)Wtsi HMGU Gross Pathology and Tissue Collection / Stomach HOM f:m Supplied as data Success
Rnlstm1b(EUCOMM)Wtsi HMGU Gross Pathology and Tissue Collection / Stomach HOM f:m Supplied as data Success
Rnlstm1b(EUCOMM)Wtsi HMGU Combined SHIRPA and Dysmorphology / Tail - length HOM 10f:10m Fisher Exact Test framework 1.00 Success
Rnlstm1b(EUCOMM)Wtsi HMGU X-ray / Number of caudal vertebrae HOM 5f:5m Not processed 1.00 FAILED - No variability in dependent variable 'IMPC_XRY_017_001'.
Rnlstm1b(EUCOMM)Wtsi HMGU Eye Morphology / Eye Hemorrhage or Blood Presence HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnlstm1b(EUCOMM)Wtsi HMGU Open Field / Number of rears - total HOM 10f:10m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.934 Success
Rnlstm1b(EUCOMM)Wtsi HMGU Combined SHIRPA and Dysmorphology / Unexpected behaviors HOM 10f:10m Fisher Exact Test framework 1.00 Success
Rnlstm1b(EUCOMM)Wtsi HMGU X-ray / Teeth HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnlstm1b(EUCOMM)Wtsi HMGU Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - Global HOM 10f:10m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.810 Success
Rnlstm1b(EUCOMM)Wtsi HMGU X-ray / Number of ribs left HOM 5f:5m Not processed 1.00 FAILED - No variability in dependent variable 'IMPC_XRY_009_001'.
Rnlstm1b(EUCOMM)Wtsi HMGU Combined SHIRPA and Dysmorphology / Hindlimbs - size HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnlstm1b(EUCOMM)Wtsi HMGU Combined SHIRPA and Dysmorphology / Skin texture - front paws HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnlstm1b(EUCOMM)Wtsi HMGU Body Composition (DEXA lean/fat) / Bone Area HOM 10f:10m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0753 Success
Rnlstm1b(EUCOMM)Wtsi HMGU Eye Morphology / Fusion between cornea and lens HOM 10f:10m Fisher Exact Test framework 1.00 Success
Rnlstm1b(EUCOMM)Wtsi HMGU Clinical Chemistry / UIBC (unsaturated iron binding capacity) HOM 10f:10m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0139 Success
Rnlstm1b(EUCOMM)Wtsi HMGU Combined SHIRPA and Dysmorphology / Coat - color - head HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnlstm1b(EUCOMM)Wtsi HMGU Hematology / Mean corpuscular hemoglobin HOM 10f:10m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.344 Success
Rnlstm1b(EUCOMM)Wtsi HMGU Echo / Cardiac Output HOM 10f:6m Mixed Model framework, linear mixed-effects model, equation withWeight 0.496 Success
Rnlstm1b(EUCOMM)Wtsi HMGU Echo / LVIDs HOM 10f:6m Mixed Model framework, linear mixed-effects model, equation withWeight 0.861 Success
Rnlstm1b(EUCOMM)Wtsi HMGU Combined SHIRPA and Dysmorphology / Hindlimb digit - shape HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnlstm1b(EUCOMM)Wtsi HMGU Intraperitoneal glucose tolerance test (IPGTT) / Fasted blood glucose concentration HOM 10f:10m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.372 Success
Rnlstm1b(EUCOMM)Wtsi HMGU Combined SHIRPA and Dysmorphology / Forepaw - size HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnlstm1b(EUCOMM)Wtsi HMGU Gross Pathology and Tissue Collection / Heart HOM f:m Supplied as data Success
Rnlstm1b(EUCOMM)Wtsi HMGU Gross Pathology and Tissue Collection / Heart HOM f:m Supplied as data Success
Rnlstm1b(EUCOMM)Wtsi HMGU Gross Pathology and Tissue Collection / Heart HOM f:m Supplied as data Success
Rnlstm1b(EUCOMM)Wtsi HMGU Gross Pathology and Tissue Collection / Heart HOM f:m Supplied as data Success
Rnlstm1b(EUCOMM)Wtsi HMGU Clinical Chemistry / Total bilirubin HOM 10f:10m Mixed Model framework, linear mixed-effects model, equation withWeight 0.710 Success
Rnlstm1b(EUCOMM)Wtsi HMGU Combined SHIRPA and Dysmorphology / Forelimbs - position HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnlstm1b(EUCOMM)Wtsi HMGU X-ray / Fusion of ribs HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnlstm1b(EUCOMM)Wtsi HMGU Body Composition (DEXA lean/fat) / BMC/Body weight HOM 10f:10m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.959 Success
Rnlstm1b(EUCOMM)Wtsi HMGU Combined SHIRPA and Dysmorphology / Lower lip morphology HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnlstm1b(EUCOMM)Wtsi HMGU Gross Pathology and Tissue Collection / Trachea HOM f:m Supplied as data Success
Rnlstm1b(EUCOMM)Wtsi HMGU Gross Pathology and Tissue Collection / Trachea HOM f:m Supplied as data Success
Rnlstm1b(EUCOMM)Wtsi HMGU Gross Pathology and Tissue Collection / Trachea HOM f:m Supplied as data Success
Rnlstm1b(EUCOMM)Wtsi HMGU Gross Pathology and Tissue Collection / Trachea HOM f:m Supplied as data Success
Rnlstm1b(EUCOMM)Wtsi HMGU Combined SHIRPA and Dysmorphology / Skin color - front paws HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnlstm1b(EUCOMM)Wtsi HMGU Gross Pathology and Tissue Collection / Testes HOM f:m Supplied as data Success
Rnlstm1b(EUCOMM)Wtsi HMGU Gross Pathology and Tissue Collection / Testes HOM f:m Supplied as data Success
Rnlstm1b(EUCOMM)Wtsi HMGU Combined SHIRPA and Dysmorphology / Coat - hair texture / appearance - abdomen HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnlstm1b(EUCOMM)Wtsi HMGU Open Field / Center resting time HOM 10f:10m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.861 Success
Rnlstm1b(EUCOMM)Wtsi HMGU Clinical Chemistry / Glucose HOM 10f:10m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.554 Success
Rnlstm1b(EUCOMM)Wtsi HMGU Eye Morphology / Retinal Blood Vessels Structure HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnlstm1b(EUCOMM)Wtsi HMGU Eye Morphology / Left total retinal thickness HOM 9f:10m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.381 Success
Rnlstm1b(EUCOMM)Wtsi HMGU X-ray / Joints HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnlstm1b(EUCOMM)Wtsi HMGU X-ray / Skull shape HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnlstm1b(EUCOMM)Wtsi HMGU Echo / Fractional Shortening HOM 10f:6m Mixed Model framework, linear mixed-effects model, equation withWeight 0.758 Success
Rnlstm1b(EUCOMM)Wtsi HMGU Combined SHIRPA and Dysmorphology / Forelimb nail - number HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnlstm1b(EUCOMM)Wtsi HMGU Combined SHIRPA and Dysmorphology / Gait HOM 10f:10m Fisher Exact Test framework 1.00 Success
Rnlstm1b(EUCOMM)Wtsi HMGU Gross Pathology and Tissue Collection / Kidney HOM f:m Supplied as data Success
Rnlstm1b(EUCOMM)Wtsi HMGU Gross Pathology and Tissue Collection / Kidney HOM f:m Supplied as data Success
Rnlstm1b(EUCOMM)Wtsi HMGU Gross Pathology and Tissue Collection / Kidney HOM f:m Supplied as data Success
Rnlstm1b(EUCOMM)Wtsi HMGU Gross Pathology and Tissue Collection / Kidney HOM f:m Supplied as data Success
Rnlstm1b(EUCOMM)Wtsi HMGU Hematology / Red blood cell distribution width HOM 10f:10m Mixed Model framework, linear mixed-effects model, equation withWeight 0.160 Success
Rnlstm1b(EUCOMM)Wtsi HMGU Electrocardiogram (ECG) / QRS HOM 10f:6m Mixed Model framework, linear mixed-effects model, equation withWeight 0.650 Success
Rnlstm1b(EUCOMM)Wtsi HMGU Combined SHIRPA and Dysmorphology / Ears HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnlstm1b(EUCOMM)Wtsi HMGU Gross Pathology and Tissue Collection / Small intestine HOM f:m Supplied as data Success
Rnlstm1b(EUCOMM)Wtsi HMGU Gross Pathology and Tissue Collection / Small intestine HOM f:m Supplied as data Success
Rnlstm1b(EUCOMM)Wtsi HMGU Gross Pathology and Tissue Collection / Small intestine HOM f:m Supplied as data Success
Rnlstm1b(EUCOMM)Wtsi HMGU Gross Pathology and Tissue Collection / Small intestine HOM f:m Supplied as data Success
Rnlstm1b(EUCOMM)Wtsi HMGU Combined SHIRPA and Dysmorphology / Forelimb digit - number HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnlstm1b(EUCOMM)Wtsi HMGU Combined SHIRPA and Dysmorphology / Tail - presence HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnlstm1b(EUCOMM)Wtsi HMGU Clinical Chemistry / Chloride HOM 10f:10m Mixed Model framework, linear mixed-effects model, equation withWeight 0.805 Success
Rnlstm1b(EUCOMM)Wtsi HMGU Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI4 HOM 10f:10m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.952 Success
Rnlstm1b(EUCOMM)Wtsi HMGU Body Composition (DEXA lean/fat) / Lean mass HOM 10f:10m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0300 Success
Rnlstm1b(EUCOMM)Wtsi HMGU Eye Morphology / Pupil Light Response HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnlstm1b(EUCOMM)Wtsi HMGU Open Field / Whole arena average speed HOM 10f:10m Mixed Model framework, linear mixed-effects model, equation withWeight 0.621 Success
Rnlstm1b(EUCOMM)Wtsi HMGU Eye Morphology / Corneal opacity HOM 10f:10m Fisher Exact Test framework 1.00 Success
Rnlstm1b(EUCOMM)Wtsi HMGU X-ray / Number of pelvic vertebrae HOM 5f:5m Not processed 1.00 FAILED - No variability in dependent variable 'IMPC_XRY_016_001'.
Rnlstm1b(EUCOMM)Wtsi HMGU Gross Pathology and Tissue Collection / Ovary HOM f:m Supplied as data Success
Rnlstm1b(EUCOMM)Wtsi HMGU Gross Pathology and Tissue Collection / Ovary HOM f:m Supplied as data Success
Rnlstm1b(EUCOMM)Wtsi HMGU Echo / Aortic diameter (Dao) HOM 10f:6m Mixed Model framework, linear mixed-effects model, equation withWeight 0.583 Success
Rnlstm1b(EUCOMM)Wtsi HMGU Gross Pathology and Tissue Collection / Eye with optic nerve HOM f:m Supplied as data Success
Rnlstm1b(EUCOMM)Wtsi HMGU Gross Pathology and Tissue Collection / Eye with optic nerve HOM f:m Supplied as data Success
Rnlstm1b(EUCOMM)Wtsi HMGU Gross Pathology and Tissue Collection / Eye with optic nerve HOM f:m Supplied as data Success
Rnlstm1b(EUCOMM)Wtsi HMGU Gross Pathology and Tissue Collection / Eye with optic nerve HOM f:m Supplied as data Success
Rnlstm1b(EUCOMM)Wtsi HMGU Hematology / White blood cell count HOM 10f:10m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.952 Success
Rnlstm1b(EUCOMM)Wtsi HMGU Combined SHIRPA and Dysmorphology / Skin color - tail HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK

 Expression

Expression data not available

 Associated Images

X-ray: XRay Images Dorso Ventral
10 Images
X-ray: XRay Images Lateral Orientation
10 Images

 Disease Models

No associations by disease annotation and gene orthology found.
Please visit the desktop version to see this section

 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Rnlstm1b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre) Mice
Rnlstm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells

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