Genes Phenotypes

Gene: Dhx40

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Name
DEAH (Asp-Glu-Ala-His) box polypeptide 40
MGI ID
MGI:1914737
Synonyms
2410016C14Rik ARG147 DDX40
Viability
Homozygous - Viable
Embryo viewer
N/A
Other links
MGI   Ensembl  
Significant phenotypes (10) Measurements chart (265) All data table (463)
Expression & images (49) Disease models (0) Order (3)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
abnormal cornea morphology Dhx40tm1b(KOMP)Wtsi HOM Early adult 6.40×10-05
abnormal bone mineralization Dhx40tm1(NCOM)Cmhd HOM Early adult 7.80×10-06
abnormal behavior Dhx40tm1(NCOM)Cmhd HOM Early adult 1.51×10-05
decreased bone mineral density Dhx40tm1(NCOM)Cmhd HOM Early adult 2.90×10-06
abnormal bone structure Dhx40tm1(NCOM)Cmhd HOM Early adult 6.13×10-06
decreased circulating cholesterol level Dhx40tm1(NCOM)Cmhd HOM Early adult 9.29×10-05
abnormal retinal blood vessel morphology Dhx40tm1b(KOMP)Wtsi HOM Early adult 5.25×10-06
decreased leukocyte cell number Dhx40tm1b(KOMP)Wtsi HOM Early adult 6.65×10-05
abnormal retinal vasculature morphology Dhx40tm1b(KOMP)Wtsi HOM Early adult 1.61×10-05
increased lean body mass Dhx40tm1b(KOMP)Wtsi HOM Early adult 8.49×10-05

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Viewing: all phenotypes
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Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584)  (2/2)  Wholemount images
Aorta 2 No  (2/2)  Wholemount images
Bone 2 No  (2/2)  Wholemount images
Brain 2 No  (2/2)  Wholemount images
Brainstem 2 No  (2/2)  Wholemount images
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No  (2/2)  Wholemount images
Cecum 2 No  (12/379) N/A
Cerebellum 2 No  (2/2)  Wholemount images
Cerebral cortex 2 No  (2/2)  Wholemount images
Esophagus 2 No  (7/415) N/A
Eye 2 No N/A
Gall bladder 2 No  (2/2) N/A
Heart 2 No  (2/2)  Wholemount images
Hippocampus 2 No  (2/2)  Wholemount images
Hypothalamus 2 No  (2/2)  Wholemount images
Kidney 2 No  (18/584)  (2/2)  Wholemount images
Large intestine 2 No  (10/584)  Wholemount images
Liver 2 No N/A
Lower urinary tract 2 No  (2/2) N/A
Lung 2 No  (2/2) N/A
Lymph node 2 No N/A
Mammary gland 2 No N/A
Olfactory lobe 2 No  (2/2)  Wholemount images
Oral epithelium 2 No N/A
Ovary 2 No  (1/584)  (1/2)  Wholemount images
Oviduct 2 No  (1/2)  Wholemount images
Pancreas 2 No  (5/584)  (2/2)  Wholemount images
Parathyroid gland 2 No  (2/2) N/A
Peripheral nervous system 2 No  (2/2)  Wholemount images
Peyer's patch 2 No N/A
Pituitary gland 2 No  (1/2)  Wholemount images
Prostate gland 2 No  (12/584) N/A
Skeletal muscle 2 No  (2/2)  Wholemount images
Skin 2 No N/A
Small intestine 2 No  (9/584) N/A
Spinal cord 2 No  (2/2) N/A
Spleen 2 No  (2/584) N/A
Stomach 2 No  (12/584) N/A
Striatum 2 No  (2/2)  Wholemount images
Testis 2 No  (2/584)  (1/2) N/A
Thymus 2 No N/A
Thyroid gland 2 No  (15/584) N/A
Trachea 2 No  (2/2) N/A
Trigeminal V nerve 2 No  (2/2)  Wholemount images
Uterus 2 No  (1/2)  Wholemount images
Vas deferens 2 No  (15/388) N/A
Vascular system 2 No  Wholemount images
White adipose tissue 2 No N/A
LacZ Wholemount Images
Unassigned Top Level MA (1)
cardiovascular system (1)
Heart expression
Vascular System no expression
Aorta expression
MA:0000072
MA:0002718
MA:0000062
digestive system (1)
Large Intestine ambiguous
MA:0000333
endocrine system (1)
Adrenal gland expression
MA:0000116
musculoskeletal system (1)
Cartilage tissue expression
Skeletal Muscle expression
Bone expression
MA:0000104
MA:0003148
MA:0001459
nervous system (4)
Cerebral Cortex expression
Brain expression
Striatum expression
Hippocampus expression
Hypothalamus expression
Cerebellum expression
Brainstem expression
Olfactory Lobe expression
MA:0000185
MA:0000168
MA:0000891
MA:0000191
MA:0000173
MA:0000198
MA:0000169
MA:0002413
postnatal mouse (12)
Adrenal gland expression
MA:0000116
reproductive system (1)
Ovary tissue not available
Oviduct tissue not available
Uterus tissue not available
MA:0000384
MA:0000385
MA:0000389
set of connective tissues (1)
Cartilage tissue expression
Skeletal Muscle expression
Bone expression
MA:0000104
MA:0003148
MA:0001459
trunk (7)
Adrenal gland expression
MA:0000116
urinary system (2)
Kidney expression
MA:0000368
LacZ Section Images
No Embryo expression data was found for this gene.

 Associated Images

Adult LacZ: LacZ Images Wholemount
13 Images
X-ray: XRay Images Whole Body Lateral Orientation
8 Images
X-ray: XRay Images Forepaw
8 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
8 Images
X-ray: XRay Images Skull Lateral Orientation
8 Images
X-ray: XRay Images Whole Body Dorso Ventral
8 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Dhx40tm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre) Mice, Tissue
Dhx40tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Dhx40tm1(NCOM)Cmhd Reporter-tagged deletion allele (with selection cassette) Targeting vectors, ES Cells

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