Gene: Alg2

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Name
asparagine-linked glycosylation 2 (alpha-1,3-mannosyltransferase)
MGI ID
MGI:1914731
Synonyms
ALPG2 CDGIi 1300013N08Rik 1110018A23Rik
Viability
Embryo viewer
N/A
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
hypoactivity Alg2tm1.1(KOMP)Vlcg HET Early adult 1.01×10-07
preweaning lethality, complete penetrance Alg2tm1.1(KOMP)Vlcg HOM   Early adult 0.00
convulsive seizures Alg2tm1.1(KOMP)Vlcg HET Early adult 1.01×10-05
embryonic lethality prior to organogenesis Alg2tm1.1(KOMP)Vlcg HOM   E9.5 0.00
increased lean body mass Alg2tm1.1(KOMP)Vlcg HET Early adult 2.36×10-06
decreased fasting circulating glucose level Alg2tm1.1(KOMP)Vlcg HET Early adult 4.21×10-08

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 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
2 No  (4/583)  (2/2)  Section images
2 No  (1/583)  (2/2)  Section images
2 No  (2/2)  Section images
2 No  (4/583)  (2/2)  Section images
2 No  (2/583)  (2/2)  Section images
2 No  (2/2)  Section images
2 No  (1/583)  (2/2)  Section images
2 No  (3/583)  (2/2)  Section images
2 No  (2/583)  (2/2)  Section images
2 No  (18/132)  (1/2)  Section images
2 No  (7/407)  (2/2)  Section images
2 No  (2/2)  Section images
2 No  (2/583)  (2/2)  Section images
2 No  (3/583)  (2/2)  Section images
2 No  (2/583)  (2/2)  Section images
2 No  (21/583)  (2/2)  Section images
2 No  (10/583)  (2/2)  Section images
2 No  (2/2)  Section images
2 No  (1/583) N/A
2 No  (2/583)  (2/2)  Section images
2 No  (1/583)  (2/2)  Section images
2 No N/A
2 No  (2/2)  Section images
2 No  (2/583)  (2/2)  Section images
2 No  (1/583)  (1/2)  Section images
2 No  (1/2)  Section images
2 No  (5/583)  (2/2)  Section images
2 No  (2/583)  (2/2)  Section images
2 No  (2/2)  Section images
2 No  (1/583)  (1/2)  Section images
2 No  (12/583) N/A
2 No  (2/2)  Section images
2 No  (1/583)  (2/2)  Section images
2 No  (9/583)  (2/2)  Section images
2 No  (3/583)  (2/2)  Section images
2 No  (3/583)  (2/2)  Section images
2 No  (13/583)  (2/2)  Section images
2 No  (3/583)  (2/2)  Section images
2 No  (2/130)  (2/2)  Section images
2 No  (6/583)  (1/2)  Section images
2 No  (2/2)  Section images
2 No  (1/583)  (2/2)  Section images
2 No  (17/583)  (2/2)  Section images
2 No  (3/583)  (2/2)  Section images
2 No  (2/2)  Section images
2 No  (1/2)  Section images
2 No  (2/2)  Section images
2 No N/A
2 No  (2/2)  Section images
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
2  (6/505)  (2/2) N/A
2  (1/60) Image Only N/A
2  (1/505)  (1/2) N/A
2  (1/506)  (2/2)  Wholemount images
2  (1/505)  (2/2) N/A
2  (1/505)  (2/2) N/A
2  (1/505)  (2/2) N/A
2  (1/505)  (2/2) N/A
2  (1/61) Image Only N/A
2  (1/505)  (2/2) N/A
2  (5/505)  (2/2) N/A
2  (1/505)  (2/2) N/A
2  (6/505)  (2/2) N/A
2  (1/505)  (2/2) N/A
2  (1/503) N/A
2  (1/503) Image Only N/A
2  (1/505)  (2/2) N/A
2  (1/505)  (2/2) N/A
2  (1/505)  (2/2) N/A
2  (1/75)  (2/2) N/A
2  (1/503) Image Only N/A
2  (1/505)  (2/2) N/A
2  (1/72)  (2/2) N/A
2  (1/505)  (2/2) N/A
2  (1/505)  (2/2) N/A

 Associated Images

Original Image
Adult LacZ: LacZ Images Section
45 Images
X-ray: XRay Images Forepaw
9 Images
Embryo LacZ: LacZ images wholemount
8 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
9 Images
X-ray: XRay Images Whole Body Dorso Ventral
9 Images
X-ray: XRay Images Skull Lateral Orientation
9 Images
Combined SHIRPA and Dysmorphology
6 Images
X-ray: XRay Images Whole Body Lateral Orientation
9 Images
Eye Morphology: Images Slit Lamp
1 Images
Electroretinography 2: Rod and cone PDF
4 Images

 Disease Models

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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Alg2tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Mice, Targeting vectors, ES Cells
Alg2tm2a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells
Alg2tm1.1(KOMP)Vlcg Reporter-tagged deletion allele (post Cre, with no selection cassette) Mice

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