Gene Summary

Name:
endoplasmic reticulum-golgi intermediate compartment 1
Synonyms:
1200007D18Rik

IMPC Data Collections

IMPC Phenotype Summary

Significant
Not Significant
Not tested

Phenotypes

The IMPC applies a panel of phenotyping screens to characterise single-gene knockout mice by comparison to wild types. Click on the different tabs to visualise significant phenotypes identified by the IMPC, as well as all data that was measured.

Phenotype System Allele Zyg Sex Life Stage P Value
preweaning lethality, complete penetrance Ergic1em1(IMPC)J HOM   Early adult 0.00
decreased grip strength Ergic1em1(IMPC)J HET Early adult 3.44×10-05

Download data as:  TSV  XLS

Select physiological systems to view:
Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

lacZ Expression

Expression data not available

Associated Images

Images submitted by IMPC centres for a selection of procedures. Each set of images is available to view in our image comparator.

Electroretinography 3

Fundus file

15 Images

Electrocardiogram (ECG)

Waveform Image

15 Images

Auditory Brain Stem Response

Click-evoked + 6 to 30kHz tone waveforms (pdf format)

8 Images

Human diseases caused by Ergic1 mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.

The table below shows human diseases associated to Ergic1 by orthology or direct annotation.

Disease Similarity of
phenotypes
Matching phenotypes Source
Neurogenic Arthrogryposis Multiplex Congenita
ORPHA:1143
Arthrogryposis Multiplex Congenita 2, Neurogenic Type
OMIM:208100

The table below shows human diseases predicted to be associated to Ergic1 by phenotypic similarity.

Disease Similarity of
phenotypes
Matching phenotypes Source
Neurogenic Arthrogryposis Multiplex Congenita
ORPHA:1143
Arthrogryposis Multiplex Congenita 2, Neurogenic Type
OMIM:208100

Histopathology

Summary table of phenotypes displayed during the Histopathology procedure which are considered significant. Full histopathology data table, including submitted images, can be accessed by clicking any row in this table.

There is no histopathology data for Ergic1

IMPC related publications

The table below lists publications which used either products generated by the IMPC or data produced by the phenotyping efforts of the IMPC. These publications have also been associated to Ergic1.

No publications found that use IMPC mice or data for Ergic1.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.

MGI Allele Allele Type Produced
Ergic1tm2a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells
Ergic1em1(IMPC)J Exon Deletion Mice
Ergic1tm2e(KOMP)Wtsi Targeted, non-conditional allele ES Cells
Ergic1tm1e(KOMP)Wtsi Targeted, non-conditional allele ES Cells

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