Gene: Myo1h

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Phenotype System Allele Zyg Sex Life Stage P Value
abnormal embryo size Myo1htm1b(KOMP)Wtsi HOM E18.5 0.00
preweaning lethality, complete penetrance Myo1htm1b(KOMP)Wtsi HOM   Early adult 0.00
abnormal motor coordination/balance Myo1htm1b(KOMP)Wtsi HET Early adult 3.08×10-11
embryonic growth retardation Myo1htm1b(KOMP)Wtsi HOM E18.5 0.00

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Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (4/584) N/A
Aorta 2 No  (1/584) N/A
Brain 2 No  (4/584)  (2/2)  Section images
Brainstem 2 No  (2/584)  (2/2)  Section images
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No  (1/584) N/A
Cerebellum 2 No  (3/584) N/A
Cerebral cortex 2 No  (2/584) N/A
Epididymis 2 No  (17/133) N/A
Esophagus 2 No  (7/408) N/A
Eye 2 No N/A
Heart 2 No  (2/584) N/A
Hippocampus 2 No  (3/584) N/A
Hypothalamus 2 No  (2/584) N/A
Kidney 2 No  (21/584)  (2/2)  Section images
Large intestine 2 No  (10/584) N/A
Liver 2 No N/A
Lower urinary tract 2 No  (1/584) N/A
Lung 2 No  (2/584)  (2/2)  Section images
Lymph node 2 No  (1/584) N/A
Mammary gland 2 No N/A
Midbrain 2 No  (2/2)  Section images
Olfactory lobe 2 No  (2/584) N/A
Ovary 2 No  (1/584)  (1/2)  Section images
Oviduct 2 No N/A
Pancreas 2 No  (5/584) N/A
Peripheral nervous system 2 No  (2/584)  (2/2)  Section images
Peyer's patch 2 No N/A
Pituitary gland 2 No  (1/584) N/A
Prostate gland 2 No  (12/584) N/A
Skeletal muscle 2 No N/A
Skin 2 No  (1/584) N/A
Small intestine 2 No  (9/584) N/A
Spinal cord 2 No  (3/584) N/A
Spleen 2 No  (3/584) N/A
Stomach 2 No  (12/584) N/A
Striatum 2 No  (3/584) N/A
Submandibular gland 2 No  (2/131)  (1/2)  Section images
Testis 2 No  (6/584)  (1/2)  Section images
Thalamus 2 No N/A
Thymus 2 No  (1/584) N/A
Thyroid gland 2 No  (16/584)  (2/2)  Section images
Trachea 2 No  (3/584)  (2/2)  Section images
Urinary bladder 2 No N/A
Uterus 2 No N/A
Vascular system 2 No N/A
Vesicular gland 2 No N/A
White adipose tissue 2 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2  (6/507)  (1/3) N/A
Dorsal root ganglion 1  (1/59) N/A
Ear 2  (1/507) N/A
Embryo 2  (1/508)  (1/3)  Wholemount images
Eye 2  (1/507) N/A
Footplate 2  (1/507) N/A
Forebrain 2  (1/507) N/A
Forelimb 2  (1/507) N/A
Fronto-nasal process 1  (1/60) N/A
Handplate 2  (1/507) N/A
Head 2  (5/507)  (1/3) N/A
Heart 2  (1/507) N/A
Hindbrain 2  (6/507)  (1/3) N/A
Hindlimb 2  (1/507) N/A
Liver 2  (1/502) N/A
Lung 2  (1/502) N/A
Mandibular process 2  (1/507) N/A
Maxillary process 2  (1/507) N/A
Midbrain 2  (1/507) N/A
Nose 1  (1/77) N/A
Oral cavity 2  (1/502) N/A
Skin 2  (1/507) N/A
Spinal cord 1  (1/71) N/A
Tail 2  (1/507) N/A
Tail somite group 2  (1/507) N/A

 Associated Images

X-ray: XRay Images Skull Dorso Ventral Orientation
10 Images
Original Image
Adult LacZ: LacZ Images Section
11 Images
X-ray: XRay Images Whole Body Lateral Orientation
10 Images
Embryo LacZ: LacZ images wholemount
8 Images
Eye Morphology: Images Ophthalmoscopy
10 Images
X-ray: XRay Images Whole Body Dorso Ventral
10 Images
X-ray: XRay Images Skull Lateral Orientation
10 Images
X-ray: XRay Images Forepaw
10 Images
Sleep Wake: Wake state (bmp file)
5 Images
Eye Morphology: Images Slit Lamp
1 Images
Auditory Brain Stem Response: Click-evoked + 6 to 30kHz tone waveforms (pdf format)
8 Images
Electroretinography 2: Rod and cone PDF
4 Images

 Disease Models

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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Myo1htm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Myo1htm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre) Mice

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