Gene: Cul4a

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Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
small testis Cul4atm1b(EUCOMM)Hmgu HOM Early adult 0.00
abnormal testis morphology Cul4atm1b(EUCOMM)Hmgu HOM Early adult 0.00
decreased mean platelet volume Cul4atm1b(EUCOMM)Hmgu HOM Early adult 1.26×10-08
increased fasting circulating glucose level Cul4atm1b(EUCOMM)Hmgu HOM Early adult 5.44×10-06
decreased circulating chloride level Cul4atm1b(EUCOMM)Hmgu HOM Early adult 2.49×10-05
male infertility Cul4atm1b(EUCOMM)Hmgu HOM Early adult 0.00

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Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584)  (2/2) N/A
Aorta 2 No  (2/2) N/A
Blood 2 No N/A
Bone 2 No  (2/2) N/A
Bone marrow 2 No N/A
Brain 2 No  (2/2) N/A
Brainstem 2 No  (2/2) N/A
Brown adipose tissue 2 No  (2/2) N/A
Cartilage tissue 2 No  (2/2) N/A
Cecum 2 No  (12/379)  (2/2) N/A
Cerebellum 2 No  (2/2) N/A
Cerebral cortex 2 No  (2/2) N/A
Chest bone 2 No  (2/2) N/A
Colon 2 No  (12/127)  (2/2) N/A
Cranium 2 No  (2/2) N/A
Diaphragm 2 No  (1/2) N/A
Duodenum 2 No  (2/127)  (2/2) N/A
Epididymis 2 No  (18/134) N/A
Esophagus 2 No  (7/415)  (2/2) N/A
Eye 2 No  (2/2) N/A
Gall bladder 2 No  (2/2) N/A
Gonadal fat pad 2 No N/A
Harderian gland 2 No  (2/2) N/A
Heart 2 No  (2/2) N/A
Hindlimb 2 No  (2/2) N/A
Hippocampus 2 No  (2/2) N/A
Hypothalamus 2 No  (2/2) N/A
Ileum 2 No  (14/127)  (2/2) N/A
Jejunum 2 No  (6/127)  (2/2) N/A
Kidney 2 No  (18/584)  (2/2) N/A
Large intestine 2 No  (10/584)  (2/2) N/A
Liver 2 No  (2/2) N/A
Lower urinary tract 2 No  (2/2) N/A
Lung 2 No  (2/2) N/A
Lymph node 2 No N/A
Main olfactory bulb 2 No N/A
Mammary gland 2 No  (1/2) N/A
Mesenteric adipose tissue 2 No N/A
Mesenteric lymph node 2 No N/A
Midbrain 2 No N/A
Olfactory lobe 2 No  (2/2) N/A
Oral epithelium 2 No  (2/2) N/A
Ovary 2 No  (1/584)  (1/2) N/A
Oviduct 2 No  (1/2) N/A
Pancreas 2 No  (5/584)  (2/2) N/A
Parathyroid gland 2 No  (2/2) N/A
Parotid gland 2 No N/A
Penis 2 No  (1/2) N/A
Peripheral nervous system 2 No  (2/2) N/A
Peyer's patch 2 No  (1/2) N/A
Pituitary gland 2 No  (2/2) N/A
Prostate gland 2 No  (12/584)  (1/2) N/A
Quadriceps 2 No  (2/2) N/A
Sciatic nerve 2 No N/A
Skeletal muscle 2 No  (2/2) N/A
Skin 2 No  (2/2) N/A
Small intestine 2 No  (9/584)  (2/2) N/A
Spinal cord 2 No  (2/2) N/A
Spleen 2 No  (2/584)  (2/2) N/A
Stomach 2 No  (12/584)  (2/2) N/A
Stomach pyloric region 2 No N/A
Striatum 2 No  (2/2) N/A
Sublingual gland 2 No N/A
Submandibular gland 2 No  (2/132)  (2/2) N/A
Testis 2 No  (2/584)  (1/2) N/A
Thalamus 2 No N/A
Thymus 2 No N/A
Thyroid gland 2 No  (15/584)  (2/2) N/A
Tongue 2 No  (5/127)  (2/2) N/A
Trachea 2 No  (2/2) N/A
Trigeminal V nerve 2 No N/A
Urinary bladder 2 No  (2/2) N/A
Uterus 2 No  (1/2) N/A
Vagina 2 No  (1/2) N/A
Vas deferens 2 No  (15/388) N/A
Vascular system 2 No  (2/2) N/A
Vesicular gland 2 No N/A
White adipose tissue 2 No  (2/2) N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2  (6/504) Image Only N/A
Central nervous system ganglion 2  (1/70) Image Only N/A
Cranium 2  (1/61) Image Only N/A
Ear 2  (1/504) Image Only N/A
Embryo 2  (1/505)  (2/2) N/A
Outer ear 2  (1/66) Image Only N/A
Eye 2  (1/504) Image Only N/A
Foot 2  (1/504) Image Only N/A
Forearm 2  (1/297) Image Only N/A
Forebrain 2  (1/504) Image Only N/A
Forelimb 2  (1/504) Image Only N/A
Hand 2  (1/503) Image Only N/A
Head 2  (5/504) Image Only N/A
Heart 2  (1/504) Image Only N/A
Hindbrain 2  (6/504) Image Only N/A
Hindlimb 2  (1/503) Image Only N/A
Humerus pre-cartilage condensation 2  (1/61) Image Only N/A
Inner ear 2  (1/61) Image Only N/A
Liver 2  (1/504) Image Only N/A
Lower leg 2  (1/297) Image Only N/A
Lung 2  (1/500) Image Only N/A
Mandibular process 2  (1/504) Image Only N/A
Maxillary process 2  (1/504) Image Only N/A
Midbrain 2  (1/504) Image Only N/A
Nose 2  (1/70) Image Only N/A
Oral cavity 2  (1/504) Image Only N/A
Radius-ulna pre-cartilage condensation 2  (1/61) Image Only N/A
Skeleton 2  (1/70) Image Only N/A
Skin 2  (1/504) Image Only N/A
Spinal cord 2  (1/69) Image Only N/A
Tail 2  (1/504) Image Only N/A
Tail somite 2  (1/504) Image Only N/A
Upper arm 2  (1/297) Image Only N/A
Upper leg 2  (1/297) Image Only N/A
Vibrissa 2  (1/66) Image Only N/A

 Associated Images

Phenotype associated images not available

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Cul4atm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Cul4atm1b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre) Mice

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