Gene: Cul4a

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Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
decreased spleen weight Cul4atm1b(EUCOMM)Hmgu HOM   Early adult 5.94×10-05
decreased circulating chloride level Cul4atm1b(EUCOMM)Hmgu HOM Early adult 8.28×10-08
increased fasting circulating glucose level Cul4atm1b(EUCOMM)Hmgu HOM Early adult 1.81×10-06
abnormal testis morphology Cul4atm1b(EUCOMM)Hmgu HOM Early adult 0.00
enhanced cued conditioning behavior Cul4atm1b(EUCOMM)Hmgu HOM Early adult 9.79×10-09
increased circulating potassium level Cul4atm1b(EUCOMM)Hmgu HOM Early adult 4.48×10-05
male infertility Cul4atm1b(EUCOMM)Hmgu HOM Early adult 0.00
small testis Cul4atm1b(EUCOMM)Hmgu HOM Early adult 0.00
decreased mean platelet volume Cul4atm1b(EUCOMM)Hmgu HOM Early adult 4.95×10-05

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Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (4/530)  (2/2)  Section images
Aorta 2 No  (1/517)  (2/2)  Section images
Blood 2 No N/A
Bone 2 No  (2/2)  Section images
Bone marrow 2 No N/A
Brain 2 No  (4/526)  (2/2)  Section images
Brainstem 2 No  (2/532)  (2/2)  Section images
Brown adipose tissue 2 No  (2/2)  Section images
Cartilage tissue 2 No  (1/538)  (2/2)  Section images
Cecum 2 No  (11/334)  (2/2)  Section images
Cerebellum 2 No  (3/537)  (2/2)  Section images
Cerebral cortex 2 No  (2/535)  (2/2)  Section images
Chest bone 2 No  (2/2)  Section images
Colon 2 No  (11/114)  (2/2)  Section images
Cranium 2 No  (2/2)  Section images
Diaphragm 2 No  (1/2)  Section images
Duodenum 2 No  (1/115)  (2/2)  Section images
Epididymis 2 No  (17/124) N/A
Esophagus 2 No  (6/377)  (2/2)  Section images
Eye 2 No  (2/2)  Section images
Gall bladder 2 No  (2/2)  Section images
Gonadal fat pad 2 No N/A
Harderian gland 2 No  (2/2)  Section images
Heart 2 No  (2/539)  (2/2)  Section images
Hindlimb 2 No  (2/2)  Section images
Hippocampus 2 No  (3/533)  (2/2)  Section images
Hypothalamus 2 No  (2/525)  (2/2)  Section images
Ileum 2 No  (13/115)  (2/2)  Section images
Jejunum 2 No  (4/109)  (2/2)  Section images
Kidney 2 No  (18/525)  (2/2)  Section images
Large intestine 2 No  (9/523)  (2/2)  Section images
Liver 2 No  (2/2)  Section images
Lower urinary tract 2 No  (1/528)  (2/2)  Section images
Lung 2 No  (1/530)  (2/2)  Section images
Lymph node 2 No  (1/531)  Section images
Main olfactory bulb 2 No N/A
Mammary gland 2 No  (1/2)  Section images
Mesenteric adipose tissue 2 No N/A
Mesenteric lymph node 2 No N/A
Midbrain 2 No N/A
Olfactory lobe 2 No  (2/508)  (2/2)  Section images
Oral epithelium 2 No  (2/2)  Section images
Ovary 2 No  (1/530)  (1/2)  Section images
Oviduct 2 No  (1/2)  Section images
Pancreas 2 No  (5/528)  (2/2)  Section images
Parathyroid gland 2 No  (1/509)  (2/2)  Section images
Parotid gland 2 No N/A
Penis 2 No  (1/2)  Section images
Peripheral nervous system 2 No  (2/532)  (2/2)  Section images
Peyer's patch 2 No  (1/2)  Section images
Pituitary gland 2 No  (2/2)  Section images
Prostate gland 2 No  (9/526)  (1/2)  Section images
Quadriceps 2 No  (2/2)  Section images
Sciatic nerve 2 No N/A
Skeletal muscle 2 No  (2/2)  Section images
Skin 2 No  (1/539)  (2/2)  Section images
Small intestine 2 No  (8/524)  (2/2)  Section images
Spinal cord 2 No  (2/527)  (2/2)  Section images
Spleen 2 No  (3/536)  (2/2)  Section images
Stomach 2 No  (12/526)  (2/2)  Section images
Stomach pyloric region 2 No N/A
Striatum 2 No  (2/521)  (2/2)  Section images
Sublingual gland 2 No N/A
Submandibular gland 2 No  (1/107)  (2/2)  Section images
Testis 2 No  (6/532)  (1/2)  Section images
Thalamus 2 No N/A
Thymus 2 No  (1/521)  Section images
Thyroid gland 2 No  (15/530)  (2/2)  Section images
Tongue 2 No  (5/117)  (2/2)  Section images
Trachea 2 No  (3/523)  (2/2)  Section images
Trigeminal V nerve 2 No N/A
Urinary bladder 2 No  (2/2)  Section images
Uterus 2 No  (1/2)  Section images
Vagina 2 No  (1/2)  Section images
Vas deferens 2 No  (12/344) N/A
Vascular system 2 No  (2/2)  Section images
Vesicular gland 2 No N/A
White adipose tissue 2 No  (2/2)  Section images
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2  (6/507) Image Only N/A
Central nervous system ganglion 2  (1/72) Image Only N/A
Cranium 2  (1/63) Image Only N/A
Ear 2  (1/507) Image Only N/A
Embryo 2  (1/508)  (2/2) N/A
External ear 2  (1/73) Image Only N/A
Eye 2  (1/507) Image Only N/A
Footplate 2  (1/507) Image Only N/A
Forearm 2  (1/304) Image Only N/A
Forebrain 2  (1/507) Image Only N/A
Forelimb 2  (1/507) Image Only N/A
Handplate 2  (1/507) Image Only N/A
Head 2  (5/507) Image Only N/A
Heart 2  (1/507) Image Only N/A
Hindbrain 2  (6/507) Image Only N/A
Hindlimb 2  (1/507) Image Only N/A
Humerus pre-cartilage condensation 2  (1/63) Image Only N/A
Inner ear 2  (1/63) Image Only N/A
Liver 2  (1/502) Image Only N/A
Lower leg 2  (1/304) Image Only N/A
Lung 2  (1/502) Image Only N/A
Mandibular process 2  (1/507) Image Only N/A
Maxillary process 2  (1/507) Image Only N/A
Midbrain 2  (1/507) Image Only N/A
Nose 2  (1/77) Image Only N/A
Oral cavity 2  (1/502) Image Only N/A
Radius-ulna pre cartilage condensation 2  (1/63) Image Only N/A
Skeleton 2  (1/77) Image Only N/A
Skin 2  (1/507) Image Only N/A
Spinal cord 2  (1/71) Image Only N/A
Tail 2  (1/507) Image Only N/A
Tail somite group 2  (1/507) Image Only N/A
Upper arm 2  (1/304) Image Only N/A
Upper leg 2  (1/304) Image Only N/A
Vibrissa 2  (1/73) Image Only N/A

 Associated Images

Adult LacZ: LacZ Images Section
122 Images
X-ray: XRay Images Whole Body Dorso Ventral
34 Images
Embryo LacZ: LacZ images wholemount
8 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
17 Images
X-ray: XRay Images Hind Leg and Hip
34 Images
X-ray: XRay Images Forepaw
17 Images
X-ray: XRay Images Skull Lateral Orientation
17 Images
X-ray: XRay Images Whole Body Lateral Orientation
17 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Cul4atm1b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre) Mice
Cul4atm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells

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